Published in Dalton Trans on August 31, 2007
Phosphate binding energy and catalysis by small and large molecules. Acc Chem Res (2008) 1.30
Luminescent chiral lanthanide(III) complexes as potential molecular probes. Dalton Trans (2009) 1.15
Correlation of relaxivity with coordination number in six-, seven-, and eight-coordinate Mn(II) complexes of pendant-arm cyclen derivatives. Inorg Chem (2009) 1.14
A promising change in the selection of the circular polarization excitation used in the measurement of Eu(III) circularly polarized luminescence. J Phys Chem A (2008) 1.02
A new approach in the preparation of dendrimer-based bifunctional diethylenetriaminepentaacetic acid MR contrast agent derivatives. Bioconjug Chem (2009) 0.96
PARACEST properties of a dinuclear neodymium(III) complex bound to DNA or carbonate. Bioconjug Chem (2009) 0.89
Activation of orotidine 5'-monophosphate decarboxylase by phosphite dianion: the whole substrate is the sum of two parts. J Am Chem Soc (2005) 2.06
Formation and stability of a vinyl carbanion at the active site of orotidine 5'-monophosphate decarboxylase: pKa of the C-6 proton of enzyme-bound UMP. J Am Chem Soc (2008) 1.85
Enzymatic catalysis of proton transfer at carbon: activation of triosephosphate isomerase by phosphite dianion. Biochemistry (2007) 1.72
A role for flexible loops in enzyme catalysis. Curr Opin Struct Biol (2010) 1.62
Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. J Am Chem Soc (2007) 1.56
A substrate in pieces: allosteric activation of glycerol 3-phosphate dehydrogenase (NAD+) by phosphite dianion. Biochemistry (2008) 1.51
Dissecting the total transition state stabilization provided by amino acid side chains at orotidine 5'-monophosphate decarboxylase: a two-part substrate approach. Biochemistry (2008) 1.45
Substituent effects on carbocation stability: the pK(R) for p-quinone methide. J Am Chem Soc (2003) 1.44
Europium(III) macrocyclic complexes with alcohol pendant groups as chemical exchange saturation transfer agents. J Am Chem Soc (2006) 1.39
Hydron transfer catalyzed by triosephosphate isomerase. Products of the direct and phosphite-activated isomerization of [1-(13)C]-glycolaldehyde in D(2)O. Biochemistry (2009) 1.33
Hydron transfer catalyzed by triosephosphate isomerase. Products of isomerization of (R)-glyceraldehyde 3-phosphate in D2O. Biochemistry (2005) 1.30
Phosphate binding energy and catalysis by small and large molecules. Acc Chem Res (2008) 1.30
Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry (2009) 1.27
Hydron transfer catalyzed by triosephosphate isomerase. Products of isomerization of dihydroxyacetone phosphate in D2O. Biochemistry (2005) 1.23
Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: effect of solvent viscosity on kinetic constants. Biochemistry (2009) 1.22
Formation and stability of peptide enolates in aqueous solution. J Am Chem Soc (2002) 1.22
Specificity in transition state binding: the Pauling model revisited. Biochemistry (2013) 1.19
An examination of the relationship between active site loop size and thermodynamic activation parameters for orotidine 5'-monophosphate decarboxylase from mesophilic and thermophilic organisms. Biochemistry (2009) 1.18
Role of Lys-12 in catalysis by triosephosphate isomerase: a two-part substrate approach. Biochemistry (2010) 1.18
Activation of R235A mutant orotidine 5'-monophosphate decarboxylase by the guanidinium cation: effective molarity of the cationic side chain of Arg-235. Biochemistry (2010) 1.17
The NiCEST approach: nickel(II) paraCEST MRI contrast agents. J Am Chem Soc (2012) 1.13
Orotidine 5'-monophosphate decarboxylase: transition state stabilization from remote protein-phosphodianion interactions. Biochemistry (2012) 1.12
Formation and stability of N-heterocyclic carbenes in water: the carbon acid pKa of imidazolium cations in aqueous solution. J Am Chem Soc (2004) 1.10
OMP decarboxylase: phosphodianion binding energy is used to stabilize a vinyl carbanion intermediate. J Am Chem Soc (2011) 1.10
Kinetic and thermodynamic barriers to carbon and oxygen alkylation of phenol and phenoxide ion by the 1-(4-methoxyphenyl)ethyl carbocation. J Am Chem Soc (2003) 1.09
A PARACEST agent responsive to inner- and outer-sphere phosphate ester interactions for MRI applications. J Am Chem Soc (2009) 1.09
Iron(II) PARACEST MRI contrast agents. J Am Chem Soc (2011) 1.09
Covalent catalysis by pyridoxal: evaluation of the effect of the cofactor on the carbon acidity of glycine. J Am Chem Soc (2007) 1.05
Scrambling of oxygen-18 during the "borderline" solvolysis of 1-(3-nitrophenyl)ethyl tosylate. Org Lett (2004) 1.05
Product deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate. J Am Chem Soc (2010) 1.03
Reactions of ion-pair intermediates of solvolysis. Chem Rec (2005) 1.03
Rescue of K12G triosephosphate isomerase by ammonium cations: the reaction of an enzyme in pieces. J Am Chem Soc (2010) 1.02
Mechanism for activation of triosephosphate isomerase by phosphite dianion: the role of a ligand-driven conformational change. J Am Chem Soc (2011) 1.01
A redox-activated MRI contrast agent that switches between paramagnetic and diamagnetic states. Angew Chem Int Ed Engl (2013) 1.00
Formation and stability of the enolates of N-protonated proline methyl ester and proline zwitterion in aqueous solution: a nonenzymatic model for the first step in the racemization of proline catalyzed by proline racemase. Biochemistry (2003) 0.99
Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent. J Am Chem Soc (2012) 0.99
A simple method to determine kinetic deuterium isotope effects provides evidence that proton transfer to carbon proceeds over and not through the reaction barrier. J Am Chem Soc (2007) 0.98
Cerium(III), europium(III), and ytterbium(III) complexes with alcohol donor groups as chemical exchange saturation transfer agents for MRI. Inorg Chem (2009) 0.98
Iron(II) complexes containing octadentate tetraazamacrocycles as paraCEST magnetic resonance imaging contrast agents. Inorg Chem (2012) 0.98
Hydrogen bonding and catalysis of solvolysis of 4-methoxybenzyl fluoride. J Am Chem Soc (2002) 0.97
Mechanism for activation of triosephosphate isomerase by phosphite dianion: the role of a hydrophobic clamp. J Am Chem Soc (2012) 0.97
Glycine enolates: the effect of formation of iminium ions to simple ketones on alpha-amino carbon acidity and a comparison with pyridoxal iminium ions. J Am Chem Soc (2008) 0.96
Wildtype and engineered monomeric triosephosphate isomerase from Trypanosoma brucei: partitioning of reaction intermediates in D2O and activation by phosphite dianion. Biochemistry (2011) 0.95
Physical and kinetic analysis of the cooperative role of metal ions in catalysis of phosphodiester cleavage by a dinuclear Zn(II) complex. J Am Chem Soc (2003) 0.95
Magnitude and origin of the enhanced basicity of the catalytic glutamate of triosephosphate isomerase. J Am Chem Soc (2013) 0.94
When does an intermediate become a transition state? Degenerate isomerization without competing racemization during solvolysis of (S)-1-(3-nitrophenyl)ethyl tosylate. J Am Chem Soc (2006) 0.94
Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation. Biochemistry (2010) 0.93
Tethered dinuclear europium(III) macrocyclic catalysts for the cleavage of RNA. J Am Chem Soc (2008) 0.92
Enzyme architecture: remarkably similar transition states for triosephosphate isomerase-catalyzed reactions of the whole substrate and the substrate in pieces. J Am Chem Soc (2014) 0.92
Substituent effects on the thermodynamic stability of imines formed from glycine and aromatic aldehydes: implications for the catalytic activity of pyridoxal-5'-phosphate. J Am Chem Soc (2009) 0.92
CoCEST: cobalt(II) amide-appended paraCEST MRI contrast agents. Chem Commun (Camb) (2013) 0.92
Claisen-type addition of glycine to pyridoxal in water. J Am Chem Soc (2004) 0.92
Slow proton transfer from the hydrogen-labelled carboxylic acid side chain (Glu-165) of triosephosphate isomerase to imidazole buffer in D2O. Org Biomol Chem (2007) 0.91
Formation and stability of the 4-methoxyphenonium ion in aqueous solution. J Org Chem (2011) 0.91
Dynamics for Reactions of Ion Pairs in Aqueous Solution: Reactivity of Tosylate Anion Ion Paired with the Highly Destabilized 1-(4-Methylphenyl)-2,2,2-Trifluoroethyl Carbocation. J Phys Org Chem (2010) 0.91
Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc(II) catalyst. J Am Chem Soc (2008) 0.90
The reactivity of macrocyclic Fe(II) paraCEST MRI contrast agents towards biologically relevant anions, cations, oxygen or peroxide. J Inorg Biochem (2012) 0.90
Structural mutations that probe the interactions between the catalytic and dianion activation sites of triosephosphate isomerase. Biochemistry (2013) 0.90
Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5'-phosphate decarboxylase-catalyzed reactions. Biochemistry (2013) 0.89
PARACEST properties of a dinuclear neodymium(III) complex bound to DNA or carbonate. Bioconjug Chem (2009) 0.89
Claisen-type addition of glycine to a pyridoxal iminium ion in water. J Org Chem (2006) 0.89
Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry (2012) 0.88
Carbon acidity of the alpha-pyridinium carbon of a pyridoxamine analog. Org Biomol Chem (2005) 0.88
Enzyme architecture: deconstruction of the enzyme-activating phosphodianion interactions of orotidine 5'-monophosphate decarboxylase. J Am Chem Soc (2014) 0.87
Structure-reactivity effects on primary deuterium isotope effects on protonation of ring-substituted alpha-methoxystyrenes. J Am Chem Soc (2009) 0.87
The activating oxydianion binding domain for enzyme-catalyzed proton transfer, hydride transfer, and decarboxylation: specificity and enzyme architecture. J Am Chem Soc (2015) 0.86
Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates. Biochemistry (2013) 0.86
Cooperativity between metal ions in the cleavage of phosphate diesters and RNA by dinuclear Zn(II) catalysts. Inorg Chem (2003) 0.86
Bovine serum albumin-catalyzed deprotonation of [1-(13)C]glycolaldehyde: protein reactivity toward deprotonation of the alpha-hydroxy alpha-carbonyl carbon. Biochemistry (2010) 0.85
Comparison of divalent transition metal ion paraCEST MRI contrast agents. J Biol Inorg Chem (2013) 0.85
Spectroscopic system for direct lanthanide photoluminescence spectroscopy with nanomolar detection limits. Appl Spectrosc (2009) 0.85
Theoretical analysis of kinetic isotope effects on proton transfer reactions between substituted alpha-methoxystyrenes and substituted acetic acids. J Am Chem Soc (2009) 0.85
Substrate specificity of an active dinuclear Zn(II) catalyst for cleavage of RNA analogues and a dinucleoside. J Am Chem Soc (2006) 0.84
Enzyme architecture: the activating oxydianion binding domain for orotidine 5'-monophophate decarboxylase. J Am Chem Soc (2013) 0.84
Structure-activity studies on the cleavage of an RNA analogue by a potent dinuclear metal ion catalyst: effect of changing the metal ion. Inorg Chem (2004) 0.84
Activation of a PARACEST agent for MRI through selective outersphere interactions with phosphate diesters. Inorg Chem (2010) 0.83
Solvent deuterium isotope effects on phosphodiester cleavage catalyzed by an extraordinarily active Zn(II) complex. J Am Chem Soc (2005) 0.83
Dynamic acylhydrazone metal ion complex libraries: a mixed-ligand approach to increased selectivity in extraction. Angew Chem Int Ed Engl (2002) 0.82
A comparison of the electrophilic reactivities of Zn2+ and acetic acid as catalysts of enolization: imperatives for enzymatic catalysis of proton transfer at carbon. J Am Chem Soc (2004) 0.82
A transition state analog for phosphate diester cleavage catalyzed by a small enzyme-like metal ion complex. Bioorg Chem (2007) 0.82
Alanine-dependent reactions of 5'-deoxypyridoxal in water. Bioorg Chem (2008) 0.81
Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase. Biochemistry (2014) 0.81
Enhancement of a Lewis acid-base interaction via solvation: ammonia molecules and the benzene radical cation. J Phys Chem A (2007) 0.81
A minimalist approach to understanding the efficiency of mononuclear Zn(II) complexes as catalysts of cleavage of an RNA analog. Dalton Trans (2007) 0.81
Eu(III) complexes as anion-responsive luminescent sensors and paramagnetic chemical exchange saturation transfer agents. Inorg Chem (2011) 0.79
Binding energy and catalysis by D-xylose isomerase: kinetic, product, and X-ray crystallographic analysis of enzyme-catalyzed isomerization of (R)-glyceraldehyde. Biochemistry (2011) 0.79
Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction. J Am Chem Soc (2012) 0.79
Substituent effects on electrophilic catalysis by the carbonyl group: anatomy of the rate acceleration for PLP-catalyzed deprotonation of glycine. J Am Chem Soc (2011) 0.79
Formation and stability of mononuclear and dinuclear Eu(III) complexes and their catalytic reactivity toward cleavage of an RNA analog. Inorg Chem (2007) 0.78
Seven-coordinate Co(II), Fe(II) and six-coordinate Ni(II) amide-appended macrocyclic complexes as ParaCEST agents in biological media. Inorg Chem (2014) 0.78
Substrate specificity for catalysis of phosphodiester cleavage by a dinuclear Zn(II) complex. Chem Commun (Camb) (2003) 0.78