Dengue.

Dengue virus pathogenesis: an integrated view. Clin Microbiol Rev (2009) 3.61

Economic impact of dengue illness in the Americas. Am J Trop Med Hyg (2011) 3.52

Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease. Cell Host Microbe (2010) 3.33

From vaccines to memory and back. Immunity (2010) 3.30

Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification. PLoS Pathog (2010) 3.16

Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis. Proc Natl Acad Sci U S A (2010) 2.97

Genomic epidemiology of a dengue virus epidemic in urban Singapore. J Virol (2009) 2.74

Arboviral etiologies of acute febrile illnesses in Western South America, 2000-2007. PLoS Negl Trop Dis (2010) 2.60

A prospective nested case-control study of Dengue in infants: rethinking and refining the antibody-dependent enhancement dengue hemorrhagic fever model. PLoS Med (2009) 2.59

Spatial evaluation and modeling of Dengue seroprevalence and vector density in Rio de Janeiro, Brazil. PLoS Negl Trop Dis (2009) 2.32

Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity. Sci Transl Med (2011) 2.29

Evaluation of commercially available anti-dengue virus immunoglobulin M tests. Emerg Infect Dis (2009) 2.26

The neglected arboviral infections in mainland China. PLoS Negl Trop Dis (2010) 2.24

Wolbachia induces reactive oxygen species (ROS)-dependent activation of the Toll pathway to control dengue virus in the mosquito Aedes aegypti. Proc Natl Acad Sci U S A (2011) 2.20

Liver involvement associated with dengue infection in adults in Vietnam. Am J Trop Med Hyg (2010) 2.10

Immature dengue virus: a veiled pathogen? PLoS Pathog (2010) 2.04

The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. Cell Host Microbe (2012) 2.03

Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness. PLoS Negl Trop Dis (2008) 1.99

A protective role for dengue virus-specific CD8+ T cells. J Immunol (2009) 1.98

Fever from the forest: prospects for the continued emergence of sylvatic dengue virus and its impact on public health. Nat Rev Microbiol (2011) 1.86

Development of real time PCR for detection and quantitation of Dengue Viruses. Virol J (2009) 1.83

The human antibody response to dengue virus infection. Viruses (2011) 1.79

Detection of dengue virus genome in urine by real-time reverse transcriptase PCR: a laboratory diagnostic method useful after disappearance of the genome in serum. J Clin Microbiol (2012) 1.79

Dengue structure differs at the temperatures of its human and mosquito hosts. Proc Natl Acad Sci U S A (2013) 1.75

Robust and Balanced Immune Responses to All 4 Dengue Virus Serotypes Following Administration of a Single Dose of a Live Attenuated Tetravalent Dengue Vaccine to Healthy, Flavivirus-Naive Adults. J Infect Dis (2015) 1.72

Dengue in India. Indian J Med Res (2012) 1.70

Immunity and immunopathology to viruses: what decides the outcome? Nat Rev Immunol (2010) 1.69

Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus. PLoS Pathog (2012) 1.69

Safety and immunogenicity of a recombinant live attenuated tetravalent dengue vaccine (DENVax) in flavivirus-naive healthy adults in Colombia: a randomised, placebo-controlled, phase 1 study. Lancet Infect Dis (2014) 1.67

Protective and enhancing HLA alleles, HLA-DRB1*0901 and HLA-A*24, for severe forms of dengue virus infection, dengue hemorrhagic fever and dengue shock syndrome. PLoS Negl Trop Dis (2008) 1.65

Economic impact of dengue illness and the cost-effectiveness of future vaccination programs in Singapore. PLoS Negl Trop Dis (2011) 1.63

Dengue in Thailand and Cambodia: an assessment of the degree of underrecognized disease burden based on reported cases. PLoS Negl Trop Dis (2011) 1.61

Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status. J Infect Dis (2011) 1.60

A mouse-passaged dengue virus strain with reduced affinity for heparan sulfate causes severe disease in mice by establishing increased systemic viral loads. J Virol (2008) 1.59

Natural strain variation and antibody neutralization of dengue serotype 3 viruses. PLoS Pathog (2010) 1.56

Factors associated with dengue shock syndrome: a systematic review and meta-analysis. PLoS Negl Trop Dis (2013) 1.55

Natural attenuation of dengue virus type-2 after a series of island outbreaks: a retrospective phylogenetic study of events in the South Pacific three decades ago. Virology (2010) 1.53

Virus identification in unknown tropical febrile illness cases using deep sequencing. PLoS Negl Trop Dis (2012) 1.52

Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion. J Virol (2009) 1.52

The early clinical features of dengue in adults: challenges for early clinical diagnosis. PLoS Negl Trop Dis (2011) 1.52

Broad antiviral activity of carbohydrate-binding agents against the four serotypes of dengue virus in monocyte-derived dendritic cells. PLoS One (2011) 1.52

Immunodominant T-cell responses to dengue virus NS3 are associated with DHF. Proc Natl Acad Sci U S A (2010) 1.49

Aedes albopictus and the reemergence of Dengue. BMC Public Health (2012) 1.48

IFI6 Inhibits Apoptosis via Mitochondrial-Dependent Pathway in Dengue Virus 2 Infected Vascular Endothelial Cells. PLoS One (2015) 1.46

OpenStructure: an integrated software framework for computational structural biology. Acta Crystallogr D Biol Crystallogr (2013) 1.46

Incidence, Characteristics and Risk Factors of Acute Kidney Injury among Dengue Patients: A Retrospective Analysis. PLoS One (2015) 1.45

Flavivirus NS4A-induced autophagy protects cells against death and enhances virus replication. J Biol Chem (2011) 1.45

Dengue virus targets the adaptor protein MITA to subvert host innate immunity. PLoS Pathog (2012) 1.44

Retracted Recent advances in DENV receptors. ScientificWorldJournal (2013) 1.43

Climate change and dengue: a critical and systematic review of quantitative modelling approaches. BMC Infect Dis (2014) 1.42

Allergies and diabetes as risk factors for dengue hemorrhagic fever: results of a case control study. PLoS Negl Trop Dis (2010) 1.41

Superior infectivity for mosquito vectors contributes to competitive displacement among strains of dengue virus. BMC Ecol (2008) 1.41

A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice. PLoS Negl Trop Dis (2010) 1.40

Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance. Proc Natl Acad Sci U S A (2011) 1.40

Dengue viruses - an overview. Infect Ecol Epidemiol (2013) 1.40

Clinical and virological factors influencing the performance of a NS1 antigen-capture assay and potential use as a marker of dengue disease severity. PLoS Negl Trop Dis (2011) 1.38

Detection of dengue virus in saliva and urine by real time RT-PCR. Virol J (2010) 1.36

Molecular epidemiology of dengue viruses in southern China from 1978 to 2006. Virol J (2011) 1.29

Cost of dengue and other febrile illnesses to households in rural Cambodia: a prospective community-based case-control study. BMC Public Health (2009) 1.27

The development of recombinant subunit envelope-based vaccines to protect against dengue virus induced disease. Vaccine (2011) 1.26

Genome-wide patterns of intrahuman dengue virus diversity reveal associations with viral phylogenetic clade and interhost diversity. J Virol (2012) 1.25

Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection. Proc Natl Acad Sci U S A (2011) 1.24

Inferring the serotype associated with dengue virus infections on the basis of pre- and postinfection neutralizing antibody titers. J Infect Dis (2010) 1.24

A brief review on dengue molecular virology, diagnosis, treatment and prevalence in Pakistan. Genet Vaccines Ther (2012) 1.21

Dynamic epidemiological models for dengue transmission: a systematic review of structural approaches. PLoS One (2012) 1.20

Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection. Cell (2015) 1.20

Therapeutic efficacy of antibodies lacking Fcγ receptor binding against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies [corrected]. PLoS Pathog (2013) 1.20

The interferon stimulator mitochondrial antiviral signaling protein facilitates cell death by disrupting the mitochondrial membrane potential and by activating caspases. J Virol (2009) 1.19

A transgenic sensor strain for monitoring the RNAi pathway in the yellow fever mosquito, Aedes aegypti. Insect Biochem Mol Biol (2008) 1.19

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun (2015) 1.18

A data-driven epidemiological prediction method for dengue outbreaks using local and remote sensing data. BMC Med Inform Decis Mak (2012) 1.18

New dengue virus type 1 genotype in Colombo, Sri Lanka. Emerg Infect Dis (2011) 1.17

A single amino acid in nonstructural protein NS4B confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis. J Virol (2011) 1.17

Differential targeting of viral components by CD4+ versus CD8+ T lymphocytes in dengue virus infection. J Virol (2012) 1.17

Molecular mimicry of human endothelial cell antigen by autoantibodies to nonstructural protein 1 of dengue virus. J Biol Chem (2011) 1.16

Epidemiological risk factors associated with high global frequency of inapparent dengue virus infections. Front Immunol (2014) 1.13

Recombinant dengue type 2 viruses with altered e protein domain III epitopes are efficiently neutralized by human immune sera. J Virol (2012) 1.12

Viral and epidemiological determinants of the invasion dynamics of novel dengue genotypes. PLoS Negl Trop Dis (2010) 1.12

Eventual role of asymptomatic cases of dengue for the introduction and spread of dengue viruses in non-endemic regions. Front Physiol (2012) 1.12

Validation of novel promoter sequences derived from two endogenous ubiquitin genes in transgenic Aedes aegypti. Insect Mol Biol (2010) 1.12

Dengue and chikungunya: long-distance spread and outbreaks in naïve areas. Pathog Glob Health (2014) 1.11

Rational design of a live attenuated dengue vaccine: 2'-o-methyltransferase mutants are highly attenuated and immunogenic in mice and macaques. PLoS Pathog (2013) 1.11

On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes. J Gen Virol (2009) 1.11

Assessing the potential of a candidate dengue vaccine with mathematical modeling. PLoS Negl Trop Dis (2012) 1.11

Murine visceral leishmaniasis: IgM and polyclonal B-cell activation lead to disease exacerbation. Eur J Immunol (2010) 1.11

Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage. Elife (2013) 1.10

Dengue: where are we today? Malays J Med Sci (2009) 1.10

Neurological complications of dengue fever: Experience from a tertiary center of north India. Ann Indian Acad Neurol (2011) 1.10

Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity. Proc Natl Acad Sci U S A (2015) 1.09

DC-SIGN (CD209) Promoter -336 A/G polymorphism is associated with dengue hemorrhagic fever and correlated to DC-SIGN expression and immune augmentation. PLoS Negl Trop Dis (2011) 1.09

Use of multiple data sources to estimate the economic cost of dengue illness in Malaysia. Am J Trop Med Hyg (2012) 1.08

Characteristic of dengue disease in Taiwan: 2002-2007. Am J Trop Med Hyg (2010) 1.08

Transient reticular gallbladder wall thickening in severe dengue fever: a reliable sign of plasma leakage. Pediatr Radiol (2009) 1.08

In vitro reconstitution reveals key intermediate states of trimer formation by the dengue virus membrane fusion protein. J Virol (2010) 1.07

The 2012 Madeira dengue outbreak: epidemiological determinants and future epidemic potential. PLoS Negl Trop Dis (2014) 1.07

Clinical and laboratory predictive markers for acute dengue infection. J Biomed Sci (2013) 1.06

Characterization of Dengue virus type 2: new insights on the 2010 Brazilian epidemic. PLoS One (2010) 1.06

Immunogenicity and safety of recombinant tetravalent dengue vaccine (CYD-TDV) in individuals aged 2-45 y: Phase II randomized controlled trial in Singapore. Hum Vaccin Immunother (2012) 1.06

Therapeutics for dengue: recommendations for design and conduct of early-phase clinical trials. PLoS Negl Trop Dis (2012) 1.05

Characterization of a model of lethal dengue virus 2 infection in C57BL/6 mice deficient in the alpha/beta interferon receptor. J Gen Virol (2012) 1.05