|
1
|
In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.
|
J Clin Invest
|
2009
|
1.17
|
|
2
|
Characterization of a mutagenic DNA adduct formed from 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase.
|
J Biol Chem
|
2003
|
1.10
|
|
3
|
Activation of bis-electrophiles to mutagenic conjugates by human O6-alkylguanine-DNA alkyltransferase.
|
Chem Res Toxicol
|
2004
|
1.10
|
|
4
|
2-amino-O4-benzylpteridine derivatives: potent inactivators of O6-alkylguanine-DNA alkyltransferase.
|
J Med Chem
|
2004
|
1.09
|
|
5
|
Human variants of O6-alkylguanine-DNA alkyltransferase.
|
DNA Repair (Amst)
|
2007
|
0.97
|
|
6
|
O6-pyridyloxobutylguanine adducts contribute to the mutagenic properties of pyridyloxobutylating agents.
|
Chem Res Toxicol
|
2005
|
0.92
|
|
7
|
Alkyltransferase-mediated toxicity of 1,3-butadiene diepoxide.
|
Chem Res Toxicol
|
2008
|
0.87
|
|
8
|
Nuclear-localizing O6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker.
|
Exp Hematol
|
2004
|
0.84
|
|
9
|
Differential inactivation of polymorphic variants of human O6-alkylguanine-DNA alkyltransferase.
|
Biochem Pharmacol
|
2007
|
0.83
|
|
10
|
Inactivation of O(6)-alkylguanine-DNA alkyltransferase by folate esters of O(6)-benzyl-2'-deoxyguanosine and of O(6)-[4-(hydroxymethyl)benzyl]guanine.
|
J Med Chem
|
2007
|
0.82
|
|
11
|
Beta-glucuronidase-cleavable prodrugs of O6-benzylguanine and O6-benzyl-2'-deoxyguanosine.
|
J Med Chem
|
2005
|
0.82
|
|
12
|
Substitution of aminomethyl at the meta-position enhances the inactivation of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine.
|
J Med Chem
|
2008
|
0.80
|
|
13
|
Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications.
|
Cancer Res
|
2008
|
0.79
|
|
14
|
Effect of O6-alkylguanine-DNA alkyltransferase on genotoxicity of epihalohydrins.
|
Environ Mol Mutagen
|
2009
|
0.78
|
|
15
|
Plasma and CNS pharmacokinetics of O4-benzylfolic acid (O4BF) and metabolite in a non-human primate model.
|
Cancer Chemother Pharmacol
|
2010
|
0.75
|