Computed tomography--an increasing source of radiation exposure.

PubWeight™: 41.06‹?› | Rank: Top 0.01% | All-Time Top 1000

🔗 View Article (PMID 18046031)

Published in N Engl J Med on November 29, 2007

Authors

David J Brenner1, Eric J Hall

Author Affiliations

1: Center for Radiological Research, Columbia University Medical Center, New York, NY 10032, USA. djb3@columbia.edu

Associated clinical trials:

Limit Computed Tomography (CT) Scanning in Suspected Renal Colic (Prospective) | NCT01352676

Gadofosveset Trisodium for Heart Imaging Studies | NCT01853592

Low-dose Protocol for Computed Tomography-guided Lung Biopsy | NCT02971176

The Watch the Spot Trial (WTS) | NCT02623712

Clinical Decision Support (CDS) for Outpatient Radiology Imaging | NCT02578290

Improving the Stewardship of Diagnostic Imaging Resources in Alberta Emergency Departments | NCT02410941

Spine Reference Parameters on EOS Imaging (EOS-SPINE) | NCT01406743

CE-U and MRE to Predict the Efficacy of Anti-TNF Therapy in Crohn's Disease (CREOLE) | NCT01183403

Whole-body Magnetic Resonance Imaging (MRI) for Staging Malignant Lymphomas | NCT00685997

Clinical Decision Support (CDS) for Radiology Imaging | NCT02996045

CT DOSE Collaboratory | NCT03000751

Integrated Computational modelIng of Right Heart Mechanics and Blood Flow Dynamics in Congenital Heart Disease | NCT03217240

Comparing Proposed Algorithm and Current Practice in the Evaluation of Suspected Appendicitis (RCTAppAlg) | NCT03324165

Early MRI Prediction of Crohns | NCT03340519

Accuracy of Ultra-Low-Dose-CT of the Chest Compared to Plain Film in an Unfiltered Emergency Department Patient Cohort (UP-Chest) | NCT03922516

The Value of Ultralow Dosis CT and Ultrasound in the Diagnosing of Pneumonia in the Emergency Department | NCT04645030

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients (NEXUS AP CT) | NCT04937868

Articles citing this

(truncated to the top 100)

Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study. Lancet (2012) 15.74

Exposure to low-dose ionizing radiation from medical imaging procedures. N Engl J Med (2009) 11.51

Cancer risk in 680,000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians. BMJ (2013) 9.38

Relevance of lung ultrasound in the diagnosis of acute respiratory failure: the BLUE protocol. Chest (2008) 7.79

The use of computed tomography in pediatrics and the associated radiation exposure and estimated cancer risk. JAMA Pediatr (2013) 6.18

An unwelcome side effect of direct-to-consumer personal genome testing: raiding the medical commons. JAMA (2008) 5.25

Use of diagnostic imaging studies and associated radiation exposure for patients enrolled in large integrated health care systems, 1996-2010. JAMA (2012) 4.71

Rising use of diagnostic medical imaging in a large integrated health system. Health Aff (Millwood) (2008) 4.05

Does clinical decision support reduce unwarranted variation in yield of CT pulmonary angiogram? Am J Med (2013) 3.67

Lung ultrasound in bronchiolitis: comparison with chest X-ray. Eur J Pediatr (2011) 3.45

Submillisievert median radiation dose for coronary angiography with a second-generation 320-detector row CT scanner in 107 consecutive patients. Radiology (2013) 3.34

The linear no-threshold relationship is inconsistent with radiation biologic and experimental data. Radiology (2009) 3.25

Cancer risk related to low-dose ionizing radiation from cardiac imaging in patients after acute myocardial infarction. CMAJ (2011) 3.15

Differences between primary care physicians' and oncologists' knowledge, attitudes and practices regarding the care of cancer survivors. J Gen Intern Med (2011) 3.11

Radiation doses to ERCP patients are significantly lower with experienced endoscopists. Gastrointest Endosc (2010) 3.10

The increasing incidence of thyroid cancer: the influence of access to care. Thyroid (2013) 3.00

Multiple testing, cumulative radiation dose, and clinical indications in patients undergoing myocardial perfusion imaging. JAMA (2010) 2.97

Evaluation of sparse-view reconstruction from flat-panel-detector cone-beam CT. Phys Med Biol (2010) 2.95

Performance comparison between total variation (TV)-based compressed sensing and statistical iterative reconstruction algorithms. Phys Med Biol (2009) 2.91

Strategies for reducing radiation dose in CT. Radiol Clin North Am (2009) 2.90

Utility of routine post-therapy surveillance imaging in diffuse large B-cell lymphoma. J Clin Oncol (2014) 2.85

Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis. Clin Gastroenterol Hepatol (2009) 2.72

Circulating tumour DNA and CT monitoring in patients with untreated diffuse large B-cell lymphoma: a correlative biomarker study. Lancet Oncol (2015) 2.64

Implementation of the Canadian C-Spine Rule: prospective 12 centre cluster randomised trial. BMJ (2009) 2.58

Diagnostic ionizing radiation exposure in a population-based cohort of patients with inflammatory bowel disease. Am J Gastroenterol (2008) 2.41

Children's exposure to diagnostic medical radiation and cancer risk: epidemiologic and dosimetric considerations. Pediatr Radiol (2008) 2.40

Use of abdominopelvic computed tomography in emergency departments and rates of urgent diagnoses in Crohn's disease. Clin Gastroenterol Hepatol (2011) 2.40

Imaging strategies for detection of urgent conditions in patients with acute abdominal pain: diagnostic accuracy study. BMJ (2009) 2.35

Early life exposure to diagnostic radiation and ultrasound scans and risk of childhood cancer: case-control study. BMJ (2011) 2.21

Development of the Crohn's disease digestive damage score, the Lémann score. Inflamm Bowel Dis (2010) 2.20

Organ doses for reference adult male and female undergoing computed tomography estimated by Monte Carlo simulations. Med Phys (2011) 2.18

Evaluation of pulmonary embolism in the emergency department and consistency with a national quality measure: quantifying the opportunity for improvement. Arch Intern Med (2012) 2.15

Abdominal CT with model-based iterative reconstruction (MBIR): initial results of a prospective trial comparing ultralow-dose with standard-dose imaging. AJR Am J Roentgenol (2012) 2.13

Use of medical imaging procedures with ionizing radiation in children: a population-based study. Arch Pediatr Adolesc Med (2011) 2.12

Low-dose X-ray CT reconstruction via dictionary learning. IEEE Trans Med Imaging (2012) 2.11

Endovascular repair of abdominal aortic aneurysm does not improve early survival versus open repair in patients younger than 60 years. Eur J Vasc Endovasc Surg (2012) 2.11

Risk stratification of emergency department patients with Crohn's disease could reduce computed tomography use by nearly half. Clin Gastroenterol Hepatol (2014) 2.08

Emergency Department Visits and Head Computed Tomography Utilization for Concussion Patients From 2006 to 2011. Acad Emerg Med (2015) 2.08

Estimated cumulative radiation dose from PET/CT in children with malignancies: a 5-year retrospective review. Pediatr Radiol (2009) 2.05

Cancer risks after radiation exposure in middle age. J Natl Cancer Inst (2010) 2.05

Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease. Radiology (2011) 2.04

The 'Image Gently' campaign: increasing CT radiation dose awareness through a national education and awareness program. Pediatr Radiol (2008) 2.03

Pediatric concussions in United States emergency departments in the years 2002 to 2006. J Pediatr (2010) 2.02

Low-dose computed tomography of the paranasal sinus and facial skull using a high-pitch dual-source system--first clinical results. Eur Radiol (2010) 2.02

Diagnostic features of prematurely fused cranial sutures on plain skull X-rays. Childs Nerv Syst (2015) 1.99

In defense of body CT. AJR Am J Roentgenol (2009) 1.96

Variations in PET/CT methodology for oncologic imaging at U.S. academic medical centers: an imaging response assessment team survey. J Nucl Med (2011) 1.95

A method to generate equivalent energy spectra and filtration models based on measurement for multidetector CT Monte Carlo dosimetry simulations. Med Phys (2009) 1.94

Radiation dose index of renal colic protocol CT studies in the United States: a report from the American College of Radiology National Radiology Data Registry. Radiology (2014) 1.93

Are pre- or postnatal diagnostic X-rays a risk factor for childhood cancer? A systematic review. Radiat Environ Biophys (2008) 1.93

Coronary artery and thoracic calcium on noncontrast thoracic CT scans: comparison of ungated and gated examinations in patients from the COPD Gene cohort. J Cardiovasc Comput Tomogr (2010) 1.91

Model-based iterative reconstruction technique for radiation dose reduction in chest CT: comparison with the adaptive statistical iterative reconstruction technique. Eur Radiol (2012) 1.89

Prediction of human observer performance in a 2-alternative forced choice low-contrast detection task using channelized Hotelling observer: impact of radiation dose and reconstruction algorithms. Med Phys (2013) 1.86

Clinical end points and response criteria in mycosis fungoides and Sézary syndrome: a consensus statement of the International Society for Cutaneous Lymphomas, the United States Cutaneous Lymphoma Consortium, and the Cutaneous Lymphoma Task Force of the European Organisation for Research and Treatment of Cancer. J Clin Oncol (2011) 1.85

Spectroscopic (multi-energy) CT distinguishes iodine and barium contrast material in MICE. Eur Radiol (2010) 1.84

ALARA, image gently and CT-induced cancer. Pediatr Radiol (2015) 1.78

Emergency department visits, use of imaging, and drugs for urolithiasis have increased in the United States. Kidney Int (2013) 1.72

Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas? J Clin Oncol (2010) 1.70

Charged particle therapy--optimization, challenges and future directions. Nat Rev Clin Oncol (2013) 1.70

Comparison of PECARN, CATCH, and CHALICE rules for children with minor head injury: a prospective cohort study. Ann Emerg Med (2014) 1.70

Monte Carlo simulations to assess the effects of tube current modulation on breast dose for multidetector CT. Phys Med Biol (2009) 1.70

Are the studies on cancer risk from CT scans biased by indication? Elements of answer from a large-scale cohort study in France. Br J Cancer (2014) 1.69

Whole-body ring-shaped confocal photoacoustic computed tomography of small animals in vivo. J Biomed Opt (2012) 1.69

Compressed sensing based cone-beam computed tomography reconstruction with a first-order method. Med Phys (2010) 1.68

Surveillance computed tomography imaging and detection of relapse in intermediate- and advanced-stage pediatric Hodgkin's lymphoma: a report from the Children's Oncology Group. J Clin Oncol (2012) 1.67

Iterative reconstruction techniques for computed tomography Part 1: technical principles. Eur Radiol (2013) 1.66

Justification of diagnostic medical exposures: some practical issues. Report of an International Atomic Energy Agency Consultation. Br J Radiol (2011) 1.66

Noise suppression in scatter correction for cone-beam CT. Med Phys (2009) 1.66

Noble metal nanoparticles applications in cancer. J Drug Deliv (2011) 1.66

Patient-specific radiation dose and cancer risk estimation in CT: part II. Application to patients. Med Phys (2011) 1.66

Radiation dose reduction in computed tomography: techniques and future perspective. Imaging Med (2009) 1.65

Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention. Ann Emerg Med (2011) 1.65

Outcome of different post-orchiectomy management for stage I seminoma: Japanese multi-institutional study including 425 patients. Int J Urol (2010) 1.65

Medical diagnostic radiation exposures and risk of gliomas. Radiat Res (2011) 1.64

CT image quality improvement using Adaptive Iterative Dose Reduction with wide-volume acquisition on 320-detector CT. Eur Radiol (2011) 1.64

Airway wall thickness assessed using computed tomography and optical coherence tomography. Am J Respir Crit Care Med (2008) 1.64

The feasibility of a piecewise-linear dynamic bowtie filter. Med Phys (2013) 1.63

Sensitivity of emergency bedside ultrasound to detect hydronephrosis in patients with computed tomography-proven stones. West J Emerg Med (2014) 1.62

Risk factor analysis for the recurrence of resected solitary fibrous tumours of the pleura: a 33-year experience and proposal for a scoring system. Eur J Cardiothorac Surg (2012) 1.61

Sensitivity of surveillance studies for detecting asymptomatic and unsuspected relapse of high-risk neuroblastoma. J Clin Oncol (2009) 1.61

Aneurysms of the ascending aorta. Dtsch Arztebl Int (2012) 1.60

Cost-effective diagnostic cardiovascular imaging: when does it provide good value for the money? Int J Cardiovasc Imaging (2010) 1.59

Automated retrieval of CT images of liver lesions on the basis of image similarity: method and preliminary results. Radiology (2010) 1.59

Avoiding CT scans in children with single-suture craniosynostosis. Childs Nerv Syst (2012) 1.59

Human pulmonary imaging and spectroscopy with hyperpolarized 129Xe at 0.2T. Acad Radiol (2008) 1.59

Assessment of the Radiation Effects of Cardiac CT Angiography Using Protein and Genetic Biomarkers. JACC Cardiovasc Imaging (2015) 1.57

Exposing exposure: enhancing patient safety through automated data mining of nuclear medicine reports for quality assurance and organ dose monitoring. Radiology (2012) 1.55

Rebalancing the risks of Computed Tomography and Magnetic Resonance imaging. Pediatr Radiol (2011) 1.54

Estimated radiation exposure from medical imaging in hemodialysis patients. J Am Soc Nephrol (2011) 1.54

Thoracic aortic calcification and coronary heart disease events: the multi-ethnic study of atherosclerosis (MESA). Atherosclerosis (2010) 1.53

Assessing cancer risks of low-dose radiation. Nat Rev Cancer (2009) 1.53

Ionizing radiation in abdominal CT: unindicated multiphase scans are an important source of medically unnecessary exposure. J Am Coll Radiol (2011) 1.52

Prospective measurement of patient exposure to radiation during pediatric ureteroscopy. J Urol (2012) 1.52

Radiation dose reduction and image enhancement in biological imaging through equally-sloped tomography. J Struct Biol (2008) 1.52

Lung ultrasound in the critically ill. Ann Intensive Care (2014) 1.52

The "post-64" era of coronary CT angiography: understanding new technology from physical principles. Radiol Clin North Am (2009) 1.51

CT radiation dose optimization and estimation: an update for radiologists. Korean J Radiol (2011) 1.51

Low plasma D-dimer concentration predicts the absence of traumatic brain injury in children. J Trauma (2010) 1.50

Derivation and Validation of Two Decision Instruments for Selective Chest CT in Blunt Trauma: A Multicenter Prospective Observational Study (NEXUS Chest CT). PLoS Med (2015) 1.50

Trends in bronchiectasis among medicare beneficiaries in the United States, 2000 to 2007. Chest (2012) 1.50

Articles by these authors

Cancer risks attributable to low doses of ionizing radiation: assessing what we really know. Proc Natl Acad Sci U S A (2003) 7.44

Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations. J Natl Cancer Inst (2006) 2.42

Managing radiation use in medical imaging: a multifaceted challenge. Radiology (2010) 2.40

Radiation oncology: a century of achievements. Nat Rev Cancer (2004) 1.98

Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblasts. Oncogene (2005) 1.58

Cancer risks from CT scans: now we have data, what next? Radiology (2012) 1.42

Secondary neutrons in clinical proton radiotherapy: a charged issue. Radiother Oncol (2008) 1.39

PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression. Nature (2003) 1.24

Improving dementia care: the role of screening and detection of cognitive impairment. Alzheimers Dement (2013) 1.19

Biological responses in known bystander cells relative to known microbeam-irradiated cells. Radiat Res (2004) 1.15

Assessment of low linear energy transfer radiation-induced bystander mutagenesis in a three-dimensional culture model. Cancer Res (2005) 1.11

Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts. Proc Natl Acad Sci U S A (2002) 1.00

Reduction of the secondary neutron dose in passively scattered proton radiotherapy, using an optimized pre-collimator/collimator. Phys Med Biol (2009) 0.98

Interaction between radiation-induced adaptive response and bystander mutagenesis in mammalian cells. Radiat Res (2003) 0.97

Combined haploinsufficiency for ATM and RAD9 as a factor in cell transformation, apoptosis, and DNA lesion repair dynamics. Cancer Res (2005) 0.96

Cancer caused by x-rays--a random event? Lancet Oncol (2007) 0.87

Demonstration of a radiation-induced bystander effect for low dose low LET beta-particles. Radiat Environ Biophys (2007) 0.87

Mrad9 and atm haploinsufficiency enhance spontaneous and X-ray-induced cataractogenesis in mice. Radiat Res (2007) 0.86

Telomere stability correlates with longevity of human beings exposed to ionizing radiations. Oncol Rep (2003) 0.84

We forget at our peril the lessons built into the α/β model. Int J Radiat Oncol Biol Phys (2012) 0.82

Toward a consensus on radiobiology teaching to radiation oncology residents. Radiat Res (2002) 0.82

Risk of cancer from diagnostic X-rays. Lancet (2004) 0.82

Combined haploinsufficiency and genetic control of the G2/M checkpoint in irradiated cells. Radiat Res (2012) 0.78

The art of sharing the diagnosis and management of Alzheimer's disease with patients and caregivers: recommendations of an expert consensus panel. Prim Care Companion J Clin Psychiatry (2010) 0.78

Prostate radiotherapy is associated with second cancers in many organs, not just the colorectum. Gastroenterology (2005) 0.78

Re: Bladder cancer risk following primary and adjuvant external beam radiation for prostate cancer. J Urol (2006) 0.77

A soft answer turneth away wrath. Proverbs 15:1. Int J Radiat Oncol Biol Phys (2009) 0.76

Hemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis. Radiat Oncol (2010) 0.76

Antiprotons for radiotherapy? Radiother Oncol (2006) 0.75