Published in Int J Chron Obstruct Pulmon Dis on January 01, 2006
Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers. Am J Respir Crit Care Med (2011) 2.12
Factors contributing to muscle wasting and dysfunction in COPD patients. Int J Chron Obstruct Pulmon Dis (2007) 1.37
Assessment of phagocytic activity of neutrophils in chronic obstructive pulmonary disease. Lung India (2015) 1.31
Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences. Int J Chron Obstruct Pulmon Dis (2011) 1.14
Role of angiogenesis and vascular remodeling in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis (2007) 1.06
Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism. J Immunol (2009) 0.99
Deregulation of apoptosis mediators' p53 and bcl2 in lung tissue of COPD patients. Respir Res (2010) 0.91
Changes in airway histone deacetylase2 in smokers and COPD with inhaled corticosteroids: a randomized controlled trial. PLoS One (2013) 0.82
Neutrophil Elastase Differentially Regulates Interleukin 8 (IL-8) and Vascular Endothelial Growth Factor (VEGF) Production by Cigarette Smoke Extract. J Biol Chem (2015) 0.81
Delayed apoptosis by neutrophils from COPD patients is associated with altered Bak, Bcl-xl, and Mcl-1 mRNA expression. Diagn Pathol (2012) 0.80
Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPD. Int J Chron Obstruct Pulmon Dis (2010) 0.79
Circulating endothelial microparticles involved in lung function decline in a rat exposed in cigarette smoke maybe from apoptotic pulmonary capillary endothelial cells. J Thorac Dis (2014) 0.78
Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers. Am J Respir Crit Care Med (2016) 0.78
Proinflammatory and prothrombotic status in emphysematous rats exposed to intermittent hypoxia. Int J Clin Exp Pathol (2015) 0.76
Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure. J Metabolomics (2015) 0.76
Evidence of eosinophil extracellular trap cell death in COPD: does it represent the trigger that switches on the disease? Int J Chron Obstruct Pulmon Dis (2017) 0.75
The role of the endothelium in asthma and chronic obstructive pulmonary disease (COPD). Respir Res (2017) 0.75
Genetic variants in ADAM33 are associated with airway inflammation and lung function in COPD. BMC Pulm Med (2014) 0.75
Mitochondria in chronic obstructive pulmonary disease and lung cancer: where are we now? Biomark Med (2017) 0.75
Flavored little cigar smoke induces cytotoxicity and apoptosis in airway epithelia. Cell Death Discov (2017) 0.75
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer (1972) 35.74
The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med (2004) 17.08
Cellular survival: a play in three Akts. Genes Dev (1999) 17.05
Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J (2004) 16.84
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest (1998) 13.05
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem (1998) 8.30
Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med (1995) 7.88
Optimal assessment and management of chronic obstructive pulmonary disease (COPD). The European Respiratory Society Task Force. Eur Respir J (1995) 7.03
Burden and clinical features of chronic obstructive pulmonary disease (COPD). Lancet (2004) 6.17
Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest (2000) 5.26
Apoptosis. Immunol Today (1993) 4.23
Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med (2001) 3.92
Alveolar wall apoptosis causes lung destruction and emphysematous changes. Am J Respir Cell Mol Biol (2003) 3.83
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem (1998) 3.78
Secreted Frizzled-related proteins: searching for relationships and patterns. Bioessays (2002) 3.22
The definition of emphysema. Report of a National Heart, Lung, and Blood Institute, Division of Lung Diseases workshop. Am Rev Respir Dis (1985) 3.21
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med (2003) 3.17
Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest (2000) 2.92
Granulocyte apoptosis and its role in the resolution and control of lung inflammation. Am J Respir Crit Care Med (1999) 2.61
Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. Am J Respir Cell Mol Biol (2003) 2.59
4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2002) 2.38
Expression of adhesion molecules during apoptosis of circulating neutrophils in COPD. Chest (2004) 2.33
Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis. J Clin Invest (2002) 2.19
Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunol Cell Biol (2003) 2.16
Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis. Am Rev Respir Dis (1993) 2.02
Skeletal muscle apoptosis and weight loss in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2002) 2.01
Skeletal muscle dysfunction in chronic obstructive pulmonary disease. A statement of the American Thoracic Society and European Respiratory Society. Am J Respir Crit Care Med (1999) 1.98
Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema. Chest (2004) 1.91
Apoptosis and emphysema: the missing link. Am J Respir Cell Mol Biol (2003) 1.82
Apoptosis: a mechanism contributing to remodeling of skeletal muscle in response to hindlimb unweighting. Am J Physiol (1997) 1.71
Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur Respir J (2001) 1.68
In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor/vascular endothelial growth factor. J Clin Invest (1996) 1.65
Structural and inflammatory changes in COPD: a comparison with asthma. Thorax (1998) 1.54
Enhanced survival of lung granulocytes in an animal model of asthma: evidence for a role of GM-CSF activated STAT5 signalling pathway. Thorax (2001) 1.52
Correlation of lung surface area to apoptosis and proliferation in human emphysema. Eur Respir J (2005) 1.51
MMP-9 as a marker of inflammation in tracheal epithelial lining fluid (TELF) and in bronchoalveolar fluid (BALF) of COPD horses. Equine Vet J (2001) 1.51
Airway inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1999) 1.48
Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness. Am J Respir Cell Mol Biol (2003) 1.46
Perforin expression and cytotoxic activity of sputum CD8+ lymphocytes in patients with COPD. Chest (2004) 1.39
Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis. Chest (2005) 1.39
Animal models for chronic obstructive pulmonary disease: age of klotho and marlboro mice. Am J Respir Cell Mol Biol (2000) 1.28
Gamma delta T cells regulate the extent and duration of inflammation in the central nervous system by a Fas ligand-dependent mechanism. J Immunol (2005) 1.25
Increased production of TGF-beta and apoptosis of T lymphocytes isolated from peripheral blood in COPD. Am J Physiol Lung Cell Mol Physiol (2003) 1.20
An increase of soluble Fas, an inhibitor of apoptosis, associated with progression of COPD. Respir Med (1998) 1.20
Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema. Am J Respir Crit Care Med (2003) 1.16
Association of tumor necrosis factor-alpha gene promoter polymorphism with low attenuation areas on high-resolution CT in patients with COPD. Chest (2002) 1.11
Cytochrome oxidase activity and mitochondrial gene expression in skeletal muscle of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1998) 1.04
Disease of the airways in chronic obstructive pulmonary disease. Eur Respir J Suppl (2001) 1.03
Myopathological features in skeletal muscle of patients with chronic obstructive pulmonary disease. Eur Respir J (2003) 1.01
Vascular atrophy and VEGFR-2 signaling: old theories of pulmonary emphysema meet new data. J Clin Invest (2000) 1.01
Nicotine prolongs neutrophil survival by suppressing apoptosis. J Lab Clin Med (1996) 1.00
Oxidant metabolism in chronic obstructive pulmonary disease. Eur Respir J Suppl (2003) 0.99
On the TRAIL to apoptosis. Cytokine Growth Factor Rev (2002) 0.97
Reduced spontaneous apoptosis in peripheral blood neutrophils during exacerbation of COPD. Eur Respir J (2004) 0.96
Induced sputum CD8+ T-lymphocyte subpopulations in chronic obstructive pulmonary disease. Respir Med (2004) 0.95
Nitrosative stress, heme oxygenase-1 expression and airway inflammation during severe exacerbations of COPD. Chest (2005) 0.93
Role of p53 in apoptosis. Adv Pharmacol (1997) 0.90
Inflammatory cell profiles and T-lymphocyte subsets in chronic obstructive pulmonary disease and severe persistent asthma. Clin Exp Allergy (2004) 0.89
Circulating levels of soluble Fas ligand and soluble Fas in patients with chronic obstructive pulmonary disease. Respir Med (2000) 0.86
Differential gene expression of sFRP-1 and apoptosis in pulmonary emphysema. Chest (2002) 0.84
Expression of 15-lipoxygenase and evidence for apoptosis in the lungs from patients with COPD Chest (2000) 0.83
Divergence of the apoptotic pathways induced by 4-hydroxynonenal and amyloid beta-protein. Neurobiol Aging (2004) 0.79
Sleep patterns in patients with acute coronary syndromes. Sleep Med (2010) 1.74
Is a miliary chest pattern always indicative of tuberculosis or malignancy? Respiration (2006) 1.67
Induced sputum versus bronchoalveolar lavage fluid in the evaluation of patients with idiopathic pulmonary fibrosis. Respiration (2005) 1.44
Smoking-related emphysema is associated with idiopathic pulmonary fibrosis and rheumatoid lung. Respirology (2013) 1.43
Exhaled breath condensate 8-isoprostane, clinical parameters, radiological indices and airway inflammation in COPD. Respiration (2007) 1.42
Idiopathic pulmonary fibrosis: outcome in relation to smoking status. Am J Respir Crit Care Med (2007) 1.41
Perforin expression and cytotoxic activity of sputum CD8+ lymphocytes in patients with COPD. Chest (2004) 1.39
Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis. Chest (2005) 1.39
Atrial overdrive pacing for the obstructive sleep apnea-hypopnea syndrome. N Engl J Med (2005) 1.26
Acute lower limb ischemia as the initial symptom of acute myeloid leukemia. Vasc Med (2007) 1.20
Dyspnea assessment and adverse events during sputum induction in COPD. BMC Pulm Med (2006) 1.15
Sleep disordered breathing in patients with acute coronary syndromes. J Clin Sleep Med (2012) 1.14
Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study. Thorax (2013) 1.13
Preventing exacerbations of COPD--advice from Hippocrates. N Engl J Med (2011) 1.11
Isolation of myeloid and plasmacytoid dendritic cells from human bronchoalveolar lavage fluid. Immunol Cell Biol (2006) 1.10
Different angiogenic activity in pulmonary sarcoidosis and idiopathic pulmonary fibrosis. Chest (2006) 1.02
Clinical presentation and management of empyema, lung abscess and pleural effusion. Curr Opin Pulm Med (2006) 0.98
Prognostic value of serum tumor markers in patients with lung cancer. Respiration (2002) 0.96
Induced sputum CD8+ T-lymphocyte subpopulations in chronic obstructive pulmonary disease. Respir Med (2004) 0.95
Is there any correlation between the ATS, BTS, ERS and GOLD COPD's severity scales and the frequency of hospital admissions? Respir Med (2004) 0.94
The relationships among hydrogen peroxide in expired breath condensate, airway inflammation, and asthma severity. Chest (2002) 0.94
Nitrosative stress, heme oxygenase-1 expression and airway inflammation during severe exacerbations of COPD. Chest (2005) 0.93
Expression profiles of Toll-like receptors in non-small cell lung cancer and idiopathic pulmonary fibrosis. Int J Oncol (2012) 0.93
Decreased small airway and alveolar CD83+ dendritic cells in COPD. Chest (2009) 0.93
Upregulation of Th1 cytokine profile (IL-12, IL-18) in bronchoalveolar lavage fluid in patients with pulmonary sarcoidosis. J Interferon Cytokine Res (2006) 0.92
Smoking and pulmonary fibrosis: novel insights. Pulm Med (2011) 0.92
Pathogenetic pathways and novel pharmacotherapeutic targets in idiopathic pulmonary fibrosis. Pulm Pharmacol Ther (2006) 0.92
Severe airway stenosis associated with Crohn's disease: case report. BMC Pulm Med (2006) 0.92
Exhaled H(2)O(2) in steady-state bronchiectasis: relationship with cellular composition in induced sputum, spirometry, and extent and severity of disease. Chest (2002) 0.91
Deregulation of apoptosis mediators' p53 and bcl2 in lung tissue of COPD patients. Respir Res (2010) 0.91
Asthma in the Elderly: Can We Distinguish It from COPD? J Allergy (Cairo) (2011) 0.90
Changes in sputum T-lymphocyte subpopulations at the onset of severe exacerbations of chronic obstructive pulmonary disease. Respir Med (2004) 0.90
Interferon-gamma 1b for the treatment of idiopathic pulmonary fibrosis. Expert Opin Biol Ther (2006) 0.90
Air travel for patients with chronic obstructive pulmonary disease: a case report. Br J Gen Pract (2012) 0.90
Expression analysis of angiogenic growth factors and biological axis CXCL12/CXCR4 axis in idiopathic pulmonary fibrosis. Connect Tissue Res (2010) 0.90
Biomarkers in COPD. Curr Med Chem (2007) 0.89
CRP evolution pattern in CPAP-treated obstructive sleep apnea patients. Does gender play a role? Sleep Breath (2011) 0.89
Decreased sputum mature dendritic cells in healthy smokers and patients with chronic obstructive pulmonary disease. Int Arch Allergy Immunol (2009) 0.89
Long-term omalizumab treatment in severe allergic asthma: the South-Eastern Mediterranean "real-life" experience. Pulm Pharmacol Ther (2011) 0.89
Angiogenic molecule Tie-2 and VEGF in the pathogenesis of pleural effusions. Respir Med (2008) 0.88
C-reactive protein evolution in obstructive sleep apnoea patients under CPAP therapy. Eur J Clin Invest (2010) 0.88
Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in Idiopathic Pulmonary Fibrosis (IPF). Respir Med (2010) 0.88
Different activity of the biological axis VEGF-Flt-1 (fms-like tyrosine kinase 1) and CXC chemokines between pulmonary sarcoidosis and idiopathic pulmonary fibrosis: a bronchoalveolar lavage study. Clin Dev Immunol (2010) 0.88
Effect of Mediterranean diet versus prudent diet combined with physical activity on OSAS: a randomised trial. Eur Respir J (2011) 0.88
Increased apoptosis of neutrophils in induced sputum of COPD patients. Respir Med (2009) 0.88
Altered surfactant protein-A expression in type II pneumocytes in COPD. Chest (2009) 0.87
Expression analysis of Akt and MAPK signaling pathways in lung tissue of patients with idiopathic pulmonary fibrosis (IPF). J Recept Signal Transduct Res (2010) 0.87
Different angiogenic CXC chemokine levels in bronchoalveolar lavage fluid after interferon gamma-1b therapy in idiopathic pulmonary fibrosis patients. Pulm Pharmacol Ther (2008) 0.87
Bronchial artery embolization for management of massive cryptogenic hemoptysis: a case series. J Med Case Rep (2011) 0.86
Effects of antifibrotic agents on TGF-beta1, CTGF and IFN-gamma expression in patients with idiopathic pulmonary fibrosis. Respir Med (2007) 0.86
Oxidative DNA damage and somatic mutations: a link to the molecular pathogenesis of chronic inflammatory airway diseases. Chest (2011) 0.86
Detection of herpes simplex virus type-1 in patients with fibrotic lung diseases. PLoS One (2011) 0.85
Molecular pathways and genetic factors in the pathogenesis of laryngopharyngeal reflux. Eur Arch Otorhinolaryngol (2009) 0.84
Pulmonary involvement and allergic disorders in inflammatory bowel disease. World J Gastroenterol (2010) 0.84
Diagnostic value of interleukin-1alpha, interleukin-6, and tumor necrosis factor in pleural effusions. Chest (2002) 0.84
Th1/Th2 cytokine pattern in bronchoalveolar lavage fluid and induced sputum in pulmonary sarcoidosis. BMC Pulm Med (2005) 0.84
Sputum and nasal lavage lung-specific biomarkers before and after smoking cessation. BMC Pulm Med (2011) 0.84
DNA damage due to oxidative stress in Chronic Obstructive Pulmonary Disease (COPD). Int J Mol Sci (2012) 0.83
Microsatellite DNA instability in benign lung diseases. Respir Med (2005) 0.83
Translation and validation of Berlin questionnaire in primary health care in Greece. BMC Pulm Med (2013) 0.83
Expression of FACIT collagens XII and XIV during bleomycin-induced pulmonary fibrosis in mice. Anat Rec A Discov Mol Cell Evol Biol (2003) 0.82
Quality of life in patients with active sarcoidosis in Greece. Eur J Intern Med (2006) 0.82
Continuous positive airway pressure therapy lowers vagal tone in patients with obstructive sleep apnoea-hypopnoea syndrome. Hellenic J Cardiol (2006) 0.82
8-Isoprostane, a marker of oxidative stress, is increased in the expired breath condensate of patients with pulmonary sarcoidosis. Chest (2004) 0.82
Immune and genetic mechanisms in COPD: possible targets for therapeutic interventions. Curr Drug Targets (2013) 0.82
Lymphangiogenesis in COPD: another link in the pathogenesis of the disease. Respir Med (2011) 0.82
Invasive cutaneous infection with Geotrichum candidum: sequential treatment with amphotericin B and voriconazole. Med Mycol (2007) 0.81
The angiogenetic pathway in malignant pleural effusions: Pathogenetic and therapeutic implications. Exp Ther Med (2010) 0.81
Prediction of obstructive sleep apnea syndrome in a large Greek population. Sleep Breath (2010) 0.81
Laser-assisted uvulopalatoplasty for the treatment of snoring and mild obstructive sleep apnea syndrome. J Otolaryngol (2003) 0.81
Histological expression of angiogenic factors: VEGF, PDGFRalpha, and HIF-1alpha in Hodgkin lymphoma. Pathol Res Pract (2008) 0.80
Response of a patient with pleural and peritoneal mesothelioma after second-line chemotherapy with lipoplatin and gemcitabine. Oncology (2008) 0.80
Effect of Mediterranean diet on lipid peroxidation marker TBARS in obese patients with OSAHS under CPAP treatment: a randomised trial. Sleep Breath (2011) 0.80
Role of VEGF-stromal cell-derived factor-1alpha/CXCL12 axis in pleural effusion of lung cancer. J Recept Signal Transduct Res (2010) 0.80
Somatic DNA alterations in lung epithelial barrier cells in COPD patients. Pulm Pharmacol Ther (2009) 0.79
Laboratory markers for COPD in "susceptible" smokers. Clin Chim Acta (2005) 0.79
Short telomeres and treatment of pulmonary fibrosis: implications for early intervention. Am J Respir Crit Care Med (2009) 0.79
Airway inflammation and cellular stress in noneosinophilic atopic asthma. Chest (2006) 0.79
Th1 cytokine pattern (IL-12 and IL-18) in bronchoalveolar lavage fluid (BALF) before and after treatment with interferon gamma-1b (IFN-gamma-1b) or colchicine in patients with idiopathic pulmonary fibrosis (IPF/UIP). Sarcoidosis Vasc Diffuse Lung Dis (2004) 0.78
A prospective analysis of 184 hemoptysis cases: diagnostic impact of chest X-ray, computed tomography, bronchoscopy. Respiration (2006) 0.78
Microsatellite DNA instability in nasal polyposis. Laryngoscope (2009) 0.78
Maintained smoking cessation for 6 months equilibrates the percentage of sputum CD8+ lymphocyte cells with that of nonsmokers. Mediators Inflamm (2010) 0.78
Novel insights into the aetiology and pathophysiology of increased airway inflammation during COPD exacerbations. Respir Res (2006) 0.78
Granule cytotoxic activity and oxidative DNA damage in smoking and nonsmoking patients with asthma. Chest (2013) 0.78
Investigation of angiogenetic pathways in nasal polyposis. Mol Med Rep (2012) 0.77
Erdheim-Chester disease: pulmonary presentation in a case with advanced systemic involvement. Respiration (2008) 0.77
Molecular response of the human diaphragm on different modes of mechanical ventilation. Respiration (2012) 0.77
Clearance of technetium-99m-DTPA and HRCT findings in the evaluation of patients with Idiopathic Pulmonary Fibrosis. BMC Pulm Med (2006) 0.77
Total lung lavage by awake flexible fiberoptic bronchoscope in a 13-year-old girl with pulmonary alveolar proteinosis. Respir Med (2006) 0.77
Intrapleural administration of lipoplatin in an animal model. Lung Cancer (2010) 0.77
Active remodeling in idiopathic interstitial pneumonias: evaluation of collagen types XII and XIV. J Histochem Cytochem (2006) 0.77
Perforin down-regulation and adhesion molecules activation in pulmonary sarcoidosis: an induced sputum and BAL study. Chest (2006) 0.77
Investigation of IL-18 and IL-12 in induced sputum of patients with IPF before and after treatment with interferon gamma-1b. Sarcoidosis Vasc Diffuse Lung Dis (2005) 0.77
Molecular profiling of EGFR family in chronic obstructive pulmonary disease: correlation with airway obstruction. Eur J Clin Invest (2013) 0.77
Acquired somatic mutations in the microsatellite DNA, in children with bronchial asthma. Pediatr Pulmonol (2009) 0.76