Published in Immunol Today on March 01, 1993
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med (2000) 5.62
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med (1995) 4.88
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med (1995) 4.20
Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin. J Exp Med (1994) 3.94
Programmed Cell Death in Plants. Plant Cell (1997) 3.64
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J (1994) 3.58
Herpes simplex virus type 1 U(L)34 gene product is required for viral envelopment. J Virol (2000) 3.06
Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition. Proc Natl Acad Sci U S A (1999) 2.85
A simple technique for quantifying apoptosis in 96-well plates. BMC Biotechnol (2005) 2.77
Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases. J Exp Med (1997) 2.76
Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci U S A (1994) 2.30
Woodchuck hepatitis virus infections: very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte. J Virol (1994) 2.29
Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock. Ann Surg (1998) 2.24
Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections. Proc Natl Acad Sci U S A (1994) 2.21
Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix. J Cell Biol (2000) 2.09
Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis. Biochem J (1996) 2.05
Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway. J Exp Med (1999) 1.99
Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am J Pathol (1995) 1.95
Recognition of oxidatively damaged and apoptotic cells by an oxidized low density lipoprotein receptor on mouse peritoneal macrophages: role of membrane phosphatidylserine. Proc Natl Acad Sci U S A (1995) 1.95
A single chicken anemia virus protein induces apoptosis. J Virol (1994) 1.91
Deficiency in fatty acid synthase leads to premature cell death and dramatic alterations in plant morphology. Plant Cell (2000) 1.84
Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells. J Clin Invest (1995) 1.81
Fine mapping of 28S rRNA sites specifically cleaved in cells undergoing apoptosis. Mol Cell Biol (1995) 1.78
Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis. Mucosal Immunol (2011) 1.76
Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J Cell Biol (1998) 1.75
Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis. J Exp Med (1995) 1.75
Apoptosis induced in CD4+ cells expressing gp160 of human immunodeficiency virus type 1. J Virol (1994) 1.67
Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation. Proc Natl Acad Sci U S A (1999) 1.56
Evidence for apoptosis of human macrophage-like HL-60 cells by Legionella pneumophila infection. Infect Immun (1996) 1.54
The c-kit ligand, stem cell factor, promotes mast cell survival by suppressing apoptosis. Am J Pathol (1994) 1.53
Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase. J Cell Biol (1998) 1.50
Apoptosis induced by inhibition of intercellular contact. J Cell Biol (1994) 1.49
Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis. J Clin Invest (2000) 1.49
Apoptosis in macrophages and alveolar epithelial cells during early stages of infection by Legionella pneumophila and its role in cytopathogenicity. Infect Immun (1999) 1.45
Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines. J Clin Invest (1994) 1.45
Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J Exp Med (1995) 1.41
H2O2 induces monocyte apoptosis and reduces viability of Mycobacterium avium-M. intracellulare within cultured human monocytes. Infect Immun (1996) 1.39
Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes. Antimicrob Agents Chemother (2001) 1.34
Apoptotic mechanisms in the pathogenesis of COPD. Int J Chron Obstruct Pulmon Dis (2006) 1.31
A novel flow cytometric method for quantifying phagocytosis of apoptotic cells. Cytometry (1997) 1.28
Comparative analysis of different methodological approaches to the in vitro study of drug-induced apoptosis. Am J Pathol (1999) 1.22
Programmed cell death in floral organs: how and why do flowers die? Ann Bot (2006) 1.20
Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils. Proc Natl Acad Sci U S A (1994) 1.19
Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure. Am J Pathol (2001) 1.19
Massive apoptosis in infantile myofibromatosis. A putative mechanism of tumor regression. Am J Pathol (1994) 1.11
Caspofungin kills Candida albicans by causing both cellular apoptosis and necrosis. Antimicrob Agents Chemother (2012) 1.09
Uses of flow cytometry in virology. Clin Microbiol Rev (1994) 1.09
Sequential transcription factor targeting for diffuse large B-cell lymphomas. Cancer Res (2008) 1.09
Differential ability of T cell subsets to undergo activation-induced cell death. Proc Natl Acad Sci U S A (1997) 1.08
Actinobacillus actinomycetemcomitans toxin induces both cell cycle arrest in the G2/M phase and apoptosis. Infect Immun (1998) 1.08
Priming of immature thymocytes to CD3-mediated apoptosis by infection with murine cytomegalovirus. J Virol (1994) 1.07
Spontaneous and Fas-induced apoptotic cell death in aged neutrophils. J Clin Immunol (1998) 1.05
Higher levels of organization in the interphase nucleus of cycling and differentiated cells. Microbiol Mol Biol Rev (2000) 1.04
Complement in neuroprotection and neurodegeneration. Trends Mol Med (2010) 1.04
Cyclosporin A blocks apoptosis by inhibiting the DNA binding activity of the transcription factor Nur77. Proc Natl Acad Sci U S A (1995) 1.03
Fas-induced programmed cell death is mediated by a Ras-regulated O2- synthesis. Immunology (1996) 1.03
Moloney murine leukemia virus-induced preleukemic thymic atrophy and enhanced thymocyte apoptosis correlate with disease pathogenicity. J Virol (1999) 1.02
Apoptosis-like programmed cell death occurs in procambium and ground meristem of pea (Pisum sativum) root tips exposed to sudden flooding. Ann Bot (2006) 1.01
The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8. PLoS Pathog (2013) 1.00
Investigation on Semecarpus Lehyam--a Siddha medicine for breast cancer. Planta (2004) 0.99
Butyric acid-induced apoptosis of murine thymocytes, splenic T cells, and human Jurkat T cells. Infect Immun (1997) 0.98
The high-affinity Fc gamma RI on PMN: regulation of expression and signal transduction. Immunology (1997) 0.97
Apoptosis and inflammation. Mediators Inflamm (1995) 0.96
Cellular and population plasticity of helper CD4(+) T cell responses. Front Physiol (2013) 0.96
Dying to live: how the death modality of the infected macrophage affects immunity to tuberculosis. Adv Exp Med Biol (2013) 0.93
UVA/UVA1 phototherapy and PUVA photochemotherapy in connective tissue diseases and related disorders: a research based review. BMC Dermatol (2004) 0.93
LESION SIMULATING DISEASE1 interacts with catalases to regulate hypersensitive cell death in Arabidopsis. Plant Physiol (2013) 0.93
Trojan horse effect: phagocyte-mediated Streptococcus iniae infection of fish. Infect Immun (2003) 0.92
Quantification of Bax/Bcl-2 ratios in peripheral blood lymphocytes, monocytes and granulocytes and their relation to susceptibility to anti-Fas (anti-CD95)-induced apoptosis. Clin Exp Immunol (1997) 0.92
Dexamethasone induces apoptosis in mouse natural killer cells and cytotoxic T lymphocytes. Immunology (1994) 0.91
Molecular mechanisms of paraptosis induction: implications for a non-genetically modified tumor vaccine. PLoS One (2009) 0.91
Temporal changes in chromatin, intracellular calcium, and poly(ADP-ribose) polymerase during Sindbis virus-induced apoptosis of neuroblastoma cells. J Virol (1996) 0.91
Immature thymocytes undergoing receptor rearrangements are resistant to an Atm-dependent death pathway activated in mature T cells by double-stranded DNA breaks. J Exp Med (2000) 0.90
Effect of ethanol on pro-apoptotic mechanisms in polarized hepatic cells. World J Gastroenterol (2007) 0.90
Molecular cloning and expression of a cDNA encoding an apoptotic endonuclease DNase gamma. Biochem J (1998) 0.90
Membrane-associated CD19-LYN complex is an endogenous p53-independent and Bc1-2-independent regulator of apoptosis in human B-lineage lymphoma cells. Proc Natl Acad Sci U S A (1995) 0.90
Apoptosis of vascular smooth muscle cells. Protein kinase C and oncoprotein Bcl-2 are involved in regulation of apoptosis in non-transformed rat vascular smooth muscle cells. Am J Pathol (1994) 0.90
Heterotrimeric G proteins and apoptosis: intersecting signaling pathways leading to context dependent phenotypes. Curr Mol Med (2009) 0.88
Role of apoptosis in autoimmunity. J Clin Immunol (2004) 0.88
Monitoring of apoptosis of HL60 cells by Fourier-transform infrared spectroscopy. Biochem J (2003) 0.87
A novel therapeutic strategy for attenuating neutrophil-mediated lung injury in vivo. Ann Surg (2002) 0.87
Necrosis and apoptosis associated with distinct Ca2+ response patterns in target cells attacked by human natural killer cells. J Physiol (1996) 0.87
Fusaric acid induces apoptosis in saffron root-tip cells: roles of caspase-like activity, cytochrome c, and H2O2. Planta (2006) 0.87
Three-dimensional microscopy characterization of death receptor 5 expression by over-activated human primary CD4+ T cells and apoptosis. PLoS One (2012) 0.86
Human melanocytes and melanoma cells constitutively express the Bcl-2 proto-oncogene in situ and in cell culture. Am J Pathol (1995) 0.86
Apoptosis of U937 cells induced by hematoporphyrin monomethyl ether-mediated sonodynamic action. Cancer Biother Radiopharm (2013) 0.85
Regulating apoptosis in mammalian cell cultures. Cytotechnology (2006) 0.85
Spontaneous apoptosis in human thymocytes. Am J Pathol (1995) 0.84
Apoptosis in the brain. Physiology and pathology. Am J Pathol (1995) 0.84
Exogenous nitric oxide inhibits apoptosis in guinea pig gastric mucous cells. Gut (2000) 0.83
Pertussis toxin inhibits activation-induced cell death of human thymocytes, pre-B leukemia cells and monocytes. J Exp Med (1994) 0.83
A peptide preparation protects cells in organotypic brain slices against cell death after glutamate intoxication. J Neural Transm (Vienna) (2005) 0.82
Antioxidant and free radical scavenging potential of yakuchinone B derivatives in reduction of lipofuscin formation using H2O2-treated neuroblastoma cells. Iran Biomed J (2011) 0.82
Plasma concentrations of growth arrest specific protein 6 and the soluble form of its tyrosine kinase receptor Axl in patients with systemic lupus erythematosus and Behçets disease. J Clin Immunol (2012) 0.82
Immunotherapy of brain cancers: the past, the present, and future directions. Clin Dev Immunol (2011) 0.81
Cytotoxic and apoptotic effects of cobalt and chromium ions on J774 macrophages - Implication of caspase-3 in the apoptotic pathway. J Mater Sci Mater Med (2004) 0.80
beta-Glucan enhanced apoptosis in human colon cancer cells SNU-C4. Nutr Res Pract (2009) 0.80
The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils. J Inflamm (Lond) (2006) 0.80
Decrease in cell surface sialic acid in etoposide-treated Jurkat cells and the role of cell surface sialidase. Glycoconj J (2000) 0.80