Published in J Mol Cell Cardiol on July 19, 2011
Regulation of the cardiac sodium pump. Cell Mol Life Sci (2012) 0.92
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling. J Mol Cell Cardiol (2013) 0.90
CaV1.2 signaling complexes in the heart. J Mol Cell Cardiol (2012) 0.90
Role of membrane microdomains in compartmentation of cAMP signaling. PLoS One (2014) 0.89
Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation. Mol Cell Proteomics (2015) 0.86
MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors. Proc Natl Acad Sci U S A (2014) 0.84
Ins and outs of GPCR signaling in primary cilia. EMBO Rep (2015) 0.84
Sarcolemmal cholesterol and caveolin-3 dependence of cardiac function, ischemic tolerance, and opioidergic cardioprotection. Am J Physiol Heart Circ Physiol (2014) 0.83
Popeye domain containing 1 (Popdc1/Bves) is a caveolae-associated protein involved in ischemia tolerance. PLoS One (2013) 0.83
ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasion. PLoS One (2013) 0.83
The cAMP-binding Popdc proteins have a redundant function in the heart. Biochem Soc Trans (2014) 0.81
Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end product. Toxicol Appl Pharmacol (2014) 0.79
MURC deficiency in smooth muscle attenuates pulmonary hypertension. Nat Commun (2016) 0.78
Identification and functional analysis of a new putative caveolin-3 variant found in a patient with sudden unexplained death. J Biomed Sci (2014) 0.77
Osmotic Stress Reduces Ca2+ Signals through Deformation of Caveolae. J Biol Chem (2015) 0.77
A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation. PLoS Comput Biol (2016) 0.77
The potential protective role of caveolin-1 in intestinal inflammation in TNBS-induced murine colitis. PLoS One (2015) 0.77
Specialized Functional Diversity and Interactions of the Na,K-ATPase. Front Physiol (2016) 0.76
Functional subcellular distribution of β1- and β2-adrenergic receptors in rat ventricular cardiac myocytes. Physiol Rep (2013) 0.76
Studying GPCR/cAMP pharmacology from the perspective of cellular structure. Front Pharmacol (2015) 0.76
Cardioprotective Role of Caveolae in Ischemia-Reperfusion Injury. Transl Med (Sunnyvale) (2013) 0.76
Caveolin contributes to the modulation of basal and β-adrenoceptor stimulated function of the adult rat ventricular myocyte by simvastatin: a novel pleiotropic effect. PLoS One (2014) 0.76
The Popeye Domain Containing Genes and cAMP Signaling. J Cardiovasc Dev Dis (2014) 0.75
Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling. Biophys Rev (2015) 0.75
Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes. Sci Rep (2017) 0.75
Donor caveolin 1 (CAV1) genetic polymorphism influences graft function after renal transplantation. Fibrogenesis Tissue Repair (2015) 0.75
A compartmentalized mathematical model of the β1-adrenergic signaling system in mouse ventricular myocytes. PLoS One (2014) 0.75
Functional rafts in cell membranes. Nature (1997) 38.89
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell (2000) 10.25
How cells handle cholesterol. Science (2000) 5.56
Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation. Science (1998) 4.58
Caveolae: from cell biology to animal physiology. Pharmacol Rev (2002) 4.45
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature (1991) 4.31
Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins. J Biol Chem (1997) 4.12
PIP2 is a necessary cofactor for ion channel function: how and why? Annu Rev Biophys (2008) 3.89
Cells respond to mechanical stress by rapid disassembly of caveolae. Cell (2011) 3.55
Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome. Circulation (2006) 3.50
Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. Science (2002) 3.46
Evidence for a regulated interaction between heterotrimeric G proteins and caveolin. J Biol Chem (1995) 3.45
Oligomeric structure of caveolin: implications for caveolae membrane organization. Proc Natl Acad Sci U S A (1995) 3.13
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science (2010) 2.99
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains. Physiol Rev (2007) 2.91
Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway. J Biol Chem (2000) 2.86
Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin. J Biol Chem (1997) 2.76
Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation. Proc Natl Acad Sci U S A (2006) 2.76
Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling. Circ Res (2006) 2.66
Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover. J Biol Chem (1998) 2.46
beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi. Proc Natl Acad Sci U S A (2003) 2.43
beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics. J Biol Chem (2007) 2.42
A genetically encoded, fluorescent indicator for cyclic AMP in living cells. Nat Cell Biol (2000) 2.34
Microtubules and actin microfilaments regulate lipid raft/caveolae localization of adenylyl cyclase signaling components. J Biol Chem (2006) 2.31
Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude. Circ Res (2002) 2.28
Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade. J Biol Chem (2002) 2.21
Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance. Circulation (2001) 2.14
Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase. J Biol Chem (2001) 2.08
Caveolar localization dictates physiologic signaling of beta 2-adrenoceptors in neonatal cardiac myocytes. J Biol Chem (2002) 2.06
eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues. Physiol Rev (2009) 1.99
Modulation of CICR has no maintained effect on systolic Ca2+: simultaneous measurements of sarcoplasmic reticulum and sarcolemmal Ca2+ fluxes in rat ventricular myocytes. J Physiol (2000) 1.98
Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes. J Biol Chem (1983) 1.93
Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains. J Biol Chem (1996) 1.92
SDPR induces membrane curvature and functions in the formation of caveolae. Nat Cell Biol (2009) 1.84
G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes. J Biol Chem (2005) 1.82
Exploring the caves: cavins, caveolins and caveolae. Trends Cell Biol (2010) 1.79
Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during beta1-adrenergic regulation. Proc Natl Acad Sci U S A (2006) 1.73
Recent developments in vascular endothelial cell transient receptor potential channels. Circ Res (2005) 1.73
Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation. J Biol Chem (2003) 1.73
Ignition of calcium sparks in arterial and cardiac muscle through caveolae. Circ Res (2000) 1.71
Phosphodiesterase 4D is required for beta2 adrenoceptor subtype-specific signaling in cardiac myocytes. Proc Natl Acad Sci U S A (2005) 1.65
Isoforms of caveolin-1 and caveolar structure. J Cell Sci (2000) 1.65
Muscarinic receptors in the mammalian heart. Pharmacol Res (2001) 1.64
Fatal cardiac arrhythmia and long-QT syndrome in a new form of congenital generalized lipodystrophy with muscle rippling (CGL4) due to PTRF-CAVIN mutations. PLoS Genet (2010) 1.62
Alpha1-adrenergic receptor signaling is localized to caveolae in neonatal rat cardiomyocytes. J Mol Cell Cardiol (2006) 1.60
Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains. Mol Biol Cell (1996) 1.60
Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circ Res (2010) 1.59
A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes. Circ Res (2006) 1.57
Subcellular [Ca2+]i gradients during excitation-contraction coupling in newborn rabbit ventricular myocytes. Circ Res (1999) 1.50
Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system. J Biol Chem (2002) 1.50
G(i) protein-mediated functional compartmentalization of cardiac beta(2)-adrenergic signaling. J Biol Chem (1999) 1.49
Caveolin-3 is adjacent to a group of extradyadic ryanodine receptors. Biophys J (2005) 1.49
Recent advances in cardiac beta(2)-adrenergic signal transduction. Circ Res (1999) 1.49
Progesterone regulates cardiac repolarization through a nongenomic pathway: an in vitro patch-clamp and computational modeling study. Circulation (2007) 1.48
Integrin mechanotransduction stimulates caveolin-1 phosphorylation and recruitment of Csk to mediate actin reorganization. Am J Physiol Heart Circ Physiol (2004) 1.46
TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophy. J Cell Sci (2008) 1.42
Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1. FASEB J (2007) 1.39
Alpha 1-adrenoceptors in myocardium: functional aspects and transmembrane signaling mechanisms. Physiol Rev (1993) 1.37
Localization of pacemaker channels in lipid rafts regulates channel kinetics. Circ Res (2004) 1.36
Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node. J Gen Physiol (2010) 1.35
Caveolae, ion channels and cardiac arrhythmias. Prog Biophys Mol Biol (2009) 1.35
Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A. J Biol Chem (1999) 1.34
Dynamic targeting of the agonist-stimulated m2 muscarinic acetylcholine receptor to caveolae in cardiac myocytes. J Biol Chem (1997) 1.33
MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. Mol Cell Biol (2008) 1.33
Localization of the sites mediating desensitization of the beta(2)-adrenergic receptor by the GRK pathway. Mol Pharmacol (2000) 1.32
Dynamic protein kinase a activities induced by beta-adrenoceptors dictate signaling propagation for substrate phosphorylation and myocyte contraction. Circ Res (2009) 1.31
Compartmentalization of phosphatidylinositol 4,5-bisphosphate in low-density membrane domains in the absence of caveolin. Biochem Biophys Res Commun (1998) 1.30
Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient. J Mol Cell Cardiol (2011) 1.29
The cytosolic domains of Ca2+-sensitive adenylyl cyclases dictate their targeting to plasma membrane lipid rafts. J Biol Chem (2004) 1.25
Modulation of the endothelial nitric-oxide synthase-caveolin interaction in cardiac myocytes. Implications for the autonomic regulation of heart rate. J Biol Chem (1998) 1.24
Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent G(s) signaling during beta2-adrenergic stimulation. Circ Res (2002) 1.24
Caveolae modulate excitation-contraction coupling and beta2-adrenergic signalling in adult rat ventricular myocytes. Cardiovasc Res (2005) 1.24
Norepinephrine- and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes. J Biol Chem (2007) 1.20
Membrane reserves and hypotonic cell swelling. J Membr Biol (2007) 1.20
Swelling-activated chloride channels in cardiac physiology and pathophysiology. Prog Biophys Mol Biol (2003) 1.19
Compartmentalisation of cAMP-dependent signalling by caveolae in the adult cardiac myocyte. J Mol Cell Cardiol (2008) 1.16
Ultrastructural distribution of calcium in smooth muscle cells of guinea-pig taenia coli. A correlated electron microscopic and quantitative study. Cell Tissue Res (1974) 1.16
Caveolin-1 and -3 dissociations from caveolae to cytosol in the heart during aging and after myocardial infarction in rat. Cardiovasc Res (2003) 1.13
Muscarinic regulation of cardiac ion channels. Br J Pharmacol (2003) 1.12
Caveolae act as membrane reserves which limit mechanosensitive I(Cl,swell) channel activation during swelling in the rat ventricular myocyte. PLoS One (2009) 1.12
Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes. J Mol Cell Cardiol (2010) 1.11
Transgenic overexpression of caveolin-3 in the heart induces a cardiomyopathic phenotype. Hum Mol Genet (2003) 1.08
Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex. Cardiovasc Res (2006) 1.08
Compartmentation of cAMP signaling in cardiac myocytes: a computational study. Biophys J (2007) 1.07
Beta-adrenergic- and muscarinic receptor-induced changes in cAMP activity in adult cardiac myocytes detected with FRET-based biosensor. Am J Physiol Cell Physiol (2005) 1.07
Cytoplasmic cAMP concentrations in intact cardiac myocytes. Am J Physiol Cell Physiol (2008) 1.07
Contribution of caveolin protein abundance to augmented nitric oxide signaling in conscious dogs with pacing-induced heart failure. Circ Res (2000) 1.07
Caveolin-1 modulates the activity of the volume-regulated chloride channel. J Physiol (1999) 1.06
Reverse mode of the Na+-Ca2+ exchange after myocardial stretch: underlying mechanism of the slow force response. Circ Res (2001) 1.06
Localization of f-channels to caveolae mediates specific beta2-adrenergic receptor modulation of rate in sinoatrial myocytes. J Mol Cell Cardiol (2006) 1.05
Developmental changes in beta2-adrenergic receptor signaling in ventricular myocytes: the role of Gi proteins and caveolae microdomains. Mol Pharmacol (2003) 1.05
Accumulation of molecules involved in alpha1-adrenergic signal within caveolae: caveolin expression and the development of cardiac hypertrophy. Cardiovasc Res (2001) 1.05
Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functions. FEBS J (2006) 1.03
cAMP microdomains and L-type Ca2+ channel regulation in guinea-pig ventricular myocytes. J Physiol (2007) 1.02
Quantitative studies on plasmalemmal folds and caveolae of rabbit ventricular myocardial cells. Circ Res (1980) 1.01
The cardiac sodium-calcium exchanger associates with caveolin-3. Ann N Y Acad Sci (2002) 1.00
Plasma membrane cyclic nucleotide phosphodiesterase 3B (PDE3B) is associated with caveolae in primary adipocytes. Cell Signal (2006) 0.99
Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol. Channels (Austin) (2007) 0.99
Autonomic regulation of voltage-gated cardiac ion channels. J Cardiovasc Electrophysiol (2006) 0.99
Inhibition of adenylyl cyclase by caveolin peptides. Endocrinology (1998) 0.98
Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes. J Mol Cell Cardiol (2010) 1.11
Store-operated Ca2+ entry in malignant hyperthermia-susceptible human skeletal muscle. J Biol Chem (2010) 0.96
A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle. J Biol Chem (2013) 0.91
The cellular basis for enhanced volume-modulated cardiac output in fish hearts. J Gen Physiol (2006) 0.89
Compartmentalized signaling in cardiomyocyte lipid domains--do structure and function match up? J Mol Cell Cardiol (2006) 0.75