Published in Psychoneuroendocrinology on December 03, 2007
Inflammation-associated depression: from serotonin to kynurenine. Psychoneuroendocrinology (2010) 2.29
Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin. J Neurosci (2009) 2.22
Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responses. J Psychosom Res (2008) 1.72
Association between pro- and anti-inflammatory cytokine genes and a symptom cluster of pain, fatigue, sleep disturbance, and depression. Cytokine (2012) 1.52
Alcoholism and inflammation: neuroimmunology of behavioral and mood disorders. Brain Behav Immun (2010) 1.11
Preliminary evidence of an association between a functional interleukin-6 polymorphism and fatigue and sleep disturbance in oncology patients and their family caregivers. J Pain Symptom Manage (2010) 1.07
Interleukin-1 inhibition and fatigue in primary Sjögren's syndrome--a double blind, randomised clinical trial. PLoS One (2012) 1.00
LPS-induced indoleamine 2,3-dioxygenase is regulated in an interferon-gamma-independent manner by a JNK signaling pathway in primary murine microglia. Brain Behav Immun (2009) 0.95
A role for orexin in cytotoxic chemotherapy-induced fatigue. Brain Behav Immun (2013) 0.93
Cytokine gene variation is associated with depressive symptom trajectories in oncology patients and family caregivers. Eur J Oncol Nurs (2012) 0.92
Chronic intermittent cold stress sensitizes neuro-immune reactivity in the rat brain. Psychoneuroendocrinology (2011) 0.90
Chronic intestinal inflammation alters hippocampal neurogenesis. J Neuroinflammation (2015) 0.90
Inducible nitric oxide synthase is involved in the modulation of depressive behaviors induced by unpredictable chronic mild stress. J Neuroinflammation (2012) 0.90
Neuroinflammation, neuroautoimmunity, and the co-morbidities of complex regional pain syndrome. J Neuroimmune Pharmacol (2012) 0.87
Influence of hypothalamic IL-6/gp130 receptor signaling on the HPA axis response to chronic stress. Psychoneuroendocrinology (2012) 0.85
Cytokine gene associations with self-report ratings of morning and evening fatigue in oncology patients and their family caregivers. Biol Res Nurs (2014) 0.85
The Lyme disease spirochete Borrelia burgdorferi induces inflammation and apoptosis in cells from dorsal root ganglia. J Neuroinflammation (2013) 0.84
Tumor necrosis factor-alpha-induced sickness behavior is impaired by central administration of an inhibitor of c-jun N-terminal kinase. Psychopharmacology (Berl) (2008) 0.81
Depression in patients with mastocytosis: prevalence, features and effects of masitinib therapy. PLoS One (2011) 0.81
The effect of TNF-alpha blockers on psychometric measures in ankylosing spondylitis patients: a preliminary observation. Rheumatol Int (2013) 0.78
Chronic peripheral inflammation, hippocampal neurogenesis, and behavior. Brain Behav Immun (2016) 0.77
Behavioral Symptoms after Breast Cancer Treatment: A Biobehavioral Approach. J Pers Med (2015) 0.77
Old Maids: Aging and Its Impact on Microglia Function. Int J Mol Sci (2017) 0.75
Mirtazapine treatment of a severe depressive episode and resolution of elevated inflammatory markers. Case Rep Psychiatry (2013) 0.75
A Conceptual Model of Psychoneurological Symptom Cluster Variation in Women with Breast Cancer: Bringing Nursing Research to Personalized Medicine. Curr Pharmacogenomics Person Med (2013) 0.75
Effect of adherence on daytime sleepiness, fatigue, depression and sleep quality in the obstructive sleep apnea/hypopnea syndrome patients undertaking nasal continuous positive airway pressure therapy. Patient Prefer Adherence (2017) 0.75
From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci (2008) 15.90
Neural systems supporting interoceptive awareness. Nat Neurosci (2004) 11.88
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci (2007) 11.24
Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol (2005) 8.49
Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation (2003) 8.29
Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation (2000) 8.17
Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol (2003) 6.89
Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest (2007) 5.55
Cytokine-associated emotional and cognitive disturbances in humans. Arch Gen Psychiatry (2001) 4.70
Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial. Lancet (2006) 4.26
Systemic infections and inflammation affect chronic neurodegeneration. Nat Rev Immunol (2007) 4.13
Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study. Lancet (1999) 4.07
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science (2000) 4.04
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia. Nat Med (2003) 3.45
Neurobehavioral effects of interferon-alpha in cancer patients: phenomenology and paroxetine responsiveness of symptom dimensions. Neuropsychopharmacology (2002) 3.24
What is immune privilege (not)? Trends Immunol (2006) 3.02
The relationship of depression and stressors to immunological assays: a meta-analytic review. Brain Behav Immun (2001) 2.89
The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine. Mol Psychiatry (2006) 2.44
Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression. Mol Psychiatry (2007) 2.38
Forebrain emotional asymmetry: a neuroanatomical basis? Trends Cogn Sci (2005) 2.34
Visualising microglial activation in vivo. Glia (2002) 2.27
Human feelings: why are some more aware than others? Trends Cogn Sci (2004) 2.02
A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol Psychiatry (2006) 1.95
The kynurenine pathway of tryptophan degradation as a drug target. Curr Opin Pharmacol (2004) 1.92
Cytokine, sickness behavior, and depression. Neurol Clin (2006) 1.58
Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis. Brain (2005) 1.51
Minocycline reduces microglial activation and improves behavioral deficits in a transgenic model of cerebral microvascular amyloid. J Neurosci (2007) 1.50
PK ('peripheral benzodiazepine')--binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microglia. J Neurocytol (1997) 1.49
Cytokines and depression: the need for a new paradigm. Brain Behav Immun (2003) 1.48
Variability of plasma IL-6 and crosslinked fibrin dimers over time in community dwelling elderly subjects. Am J Clin Pathol (1994) 1.46
Bacille Calmette-Guérin inoculation induces chronic activation of peripheral and brain indoleamine 2,3-dioxygenase in mice. J Infect Dis (2005) 1.45
Cancer-related fatigue: links with inflammation in cancer patients and survivors. Brain Behav Immun (2007) 1.42
Assessment of tumor necrosis factor alpha blockade as an intervention to improve tolerability of dose-intensive chemotherapy in cancer patients. J Clin Oncol (2006) 1.37
Age-related effects of interleukin-1 beta on polymorphonuclear neutrophil-dependent increases in blood-brain barrier permeability in rats. Brain (1997) 1.37
The enzyme indoleamine 2,3-dioxygenase is induced in the mouse brain in response to peripheral administration of lipopolysaccharide and superantigen. Brain Behav Immun (2002) 1.35
Sub-pyrogenic systemic inflammation impacts on brain and behavior, independent of cytokines. Brain Behav Immun (2007) 1.34
Resources for integrative systems biology: from data through databases to networks and dynamic system models. Brief Bioinform (2006) 1.20
Detection of vascular expression of E-selectin in vivo with MR imaging. Radiology (2006) 1.18
Inactivation of the cerebral NFkappaB pathway inhibits interleukin-1beta-induced sickness behavior and c-Fos expression in various brain nuclei. Neuropsychopharmacology (2005) 1.15
MRI detection of early endothelial activation in brain inflammation. Magn Reson Med (2004) 1.11
The role of MRI as a surrogate outcome measure in multiple sclerosis. Mult Scler (2002) 1.09
Endogenous regulation of the acute inflammatory response. Mol Cell Biochem (2002) 1.08
Cannabis use and anxiety in daily life: a naturalistic investigation in a non-clinical population. Psychiatry Res (2003) 1.06
Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Ann Neurol (2005) 1.05
Biological variation of interleukin 6 (IL-6) and soluble interleukin 2 receptor (sIL2R) in serum of healthy individuals. Cytokine (2000) 1.03
Inhibitors of stress-activated protein/mitogen-activated protein kinase pathways. Curr Opin Pharmacol (2007) 0.98
Cardiovascular biomarkers: added value with an integrated approach? Circulation (2007) 0.97
Effects of the common cold on mood and performance. Psychoneuroendocrinology (1998) 0.96
C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts. Endocrinology (2006) 0.96
Taking fatigue seriously, II: variability in fatigue levels in cancer patients. Psychosomatics (2007) 0.96
Adhesion molecule expression on murine cerebral endothelium following the injection of a proinflammagen or during acute neuronal degeneration. J Neurocytol (1995) 0.95
The variability and accurate assessment of microinflammation in haemodialysis patients. Nephrol Dial Transplant (2004) 0.94
Discrimination ratio analysis of inflammatory markers: implications for the study of inflammation in chronic disease. Metabolism (2004) 0.92
Specific E-selectin targeting with a superparamagnetic MRI contrast agent. Contrast Media Mol Imaging (2006) 0.89
Cytokine mediation of experimental heart failure-induced anhedonia. Am J Physiol Regul Integr Comp Physiol (2003) 0.86
Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol (2005) 8.49
Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry (2005) 4.81
The link between childhood trauma and depression: insights from HPA axis studies in humans. Psychoneuroendocrinology (2008) 4.35
When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatry (2003) 3.68
Somatic symptom disorder: an important change in DSM. J Psychosom Res (2013) 3.40
Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress. Am J Psychiatry (2006) 3.33
Neuroendocrine-immune mechanisms of behavioral comorbidities in patients with cancer. J Clin Oncol (2008) 3.30
Neurobehavioral effects of interferon-alpha in cancer patients: phenomenology and paroxetine responsiveness of symptom dimensions. Neuropsychopharmacology (2002) 3.24
Childhood trauma associated with smaller hippocampal volume in women with major depression. Am J Psychiatry (2002) 3.05
To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers. Brain Behav Immun (2009) 3.00
Cytokines and psychopathology: lessons from interferon-alpha. Biol Psychiatry (2004) 2.83
Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression. Brain Behav Immun (2006) 2.78
Depressive disorders and immunity: 20 years of progress and discovery. Brain Behav Immun (2007) 2.75
Inflammatory biomarkers for persistent fatigue in breast cancer survivors. Clin Cancer Res (2006) 2.69
A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers. JAMA Psychiatry (2013) 2.68
Validation of a 3-factor scoring model for the Pittsburgh sleep quality index in older adults. Sleep (2006) 2.62
Depressive symptoms and viral clearance in patients receiving interferon-alpha and ribavirin for hepatitis C. Brain Behav Immun (2005) 2.52
Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms. Cancer (2003) 2.48
Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior. Neuropsychopharmacology (2011) 2.31
Chronic stress and regulation of cellular markers of inflammation in rheumatoid arthritis: implications for fatigue. Brain Behav Immun (2007) 2.18
Varicella-zoster virus-specific immune responses to herpes zoster in elderly participants in a trial of a clinically effective zoster vaccine. J Infect Dis (2009) 2.13
Immune system to brain signaling: neuropsychopharmacological implications. Pharmacol Ther (2011) 2.12
Reversible modulations of neuronal plasticity by VEGF. Proc Natl Acad Sci U S A (2011) 2.06
Inflammation and behavioral symptoms after breast cancer treatment: do fatigue, depression, and sleep disturbance share a common underlying mechanism? J Clin Oncol (2011) 2.05
Interferon-alpha-induced changes in tryptophan metabolism. relationship to depression and paroxetine treatment. Biol Psychiatry (2003) 2.05
Activation of central nervous system inflammatory pathways by interferon-alpha: relationship to monoamines and depression. Biol Psychiatry (2008) 1.96
Inflammation-induced anhedonia: endotoxin reduces ventral striatum responses to reward. Biol Psychiatry (2010) 1.95
Neuropsychiatric adverse effects of interferon-alpha: recognition and management. CNS Drugs (2005) 1.93
Depression in cancer: new developments regarding diagnosis and treatment. Biol Psychiatry (2003) 1.92
Association of exaggerated HPA axis response to the initial injection of interferon-alpha with development of depression during interferon-alpha therapy. Am J Psychiatry (2003) 1.90
A cytokine-based neuroimmunologic mechanism of cancer-related symptoms. Neuroimmunomodulation (2004) 1.87
Cognitive complaints after breast cancer treatments: examining the relationship with neuropsychological test performance. J Natl Cancer Inst (2013) 1.86
Mindfulness-Based Stress Reduction training reduces loneliness and pro-inflammatory gene expression in older adults: a small randomized controlled trial. Brain Behav Immun (2012) 1.86
Inflammation and social experience: an inflammatory challenge induces feelings of social disconnection in addition to depressed mood. Brain Behav Immun (2010) 1.85
Comparison of cognitive behavioral and mindfulness meditation interventions on adaptation to rheumatoid arthritis for patients with and without history of recurrent depression. J Consult Clin Psychol (2008) 1.80
Anterior cingulate activation and error processing during interferon-alpha treatment. Biol Psychiatry (2005) 1.80
An fMRI study of cytokine-induced depressed mood and social pain: the role of sex differences. Neuroimage (2009) 1.79
A dual role for interleukin-1 in hippocampal-dependent memory processes. Psychoneuroendocrinology (2007) 1.77
Inflammatory markers and sleep disturbance in major depression. Psychosom Med (2005) 1.72
The role of early adverse experience and adulthood stress in the prediction of neuroendocrine stress reactivity in women: a multiple regression analysis. Depress Anxiety (2002) 1.72
Depressive symptoms and metabolic syndrome: is inflammation the underlying link? Biol Psychiatry (2008) 1.70
Yoga for persistent fatigue in breast cancer survivors: a randomized controlled trial. Cancer (2011) 1.67
Immune modulation of the hypothalamic-pituitary-adrenal (HPA) axis during viral infection. Viral Immunol (2005) 1.63
Basal ganglia hypermetabolism and symptoms of fatigue during interferon-alpha therapy. Neuropsychopharmacology (2007) 1.63
Yogic meditation reverses NF-κB and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial. Psychoneuroendocrinology (2012) 1.63
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. Glia (2002) 1.60
Is depression an inflammatory disorder? Curr Psychiatry Rep (2011) 1.60
Depression during pegylated interferon-alpha plus ribavirin therapy: prevalence and prediction. J Clin Psychiatry (2005) 1.58
Skeletal parasympathetic innervation communicates central IL-1 signals regulating bone mass accrual. Proc Natl Acad Sci U S A (2012) 1.56
Craving love? Enduring grief activates brain's reward center. Neuroimage (2008) 1.54
Low-dose endotoxemia and human neuropsychological functions. Brain Behav Immun (2005) 1.53
Impaired interleukin-1 signaling is associated with deficits in hippocampal memory processes and neural plasticity. Hippocampus (2003) 1.52
A multidimensional model of fatigue in patients with rheumatoid arthritis. J Rheumatol (2012) 1.52
Effects of interferon-alpha on rhesus monkeys: a nonhuman primate model of cytokine-induced depression. Biol Psychiatry (2007) 1.51
Characterization of an interleukin-6- and adrenocorticotropin-dependent, immune-to-adrenal pathway during viral infection. Endocrinology (2004) 1.51
Adherence to the mediterranean diet is inversely associated with circulating interleukin-6 among middle-aged men: a twin study. Circulation (2007) 1.51
Dopaminergic mechanisms of reduced basal ganglia responses to hedonic reward during interferon alfa administration. Arch Gen Psychiatry (2012) 1.48
Inflammatory responses to psychological stress in fatigued breast cancer survivors: relationship to glucocorticoids. Brain Behav Immun (2006) 1.47
Interleukin-1 (IL-1): a central regulator of stress responses. Front Neuroendocrinol (2008) 1.46
Health consequences of Alzheimer's caregiving transitions: effects of placement and bereavement. Psychosom Med (2002) 1.44
Baseline mood and psychosocial characteristics of patients developing depressive symptoms during interleukin-2 and/or interferon-alpha cancer therapy. Brain Behav Immun (2004) 1.43
Dietary patterns derived by hybrid clustering method in older people: association with cognition, mood, and self-rated health. J Am Diet Assoc (2008) 1.43
Eating ourselves to death (and despair): the contribution of adiposity and inflammation to depression. Prog Neurobiol (2010) 1.38
Sleep disturbance and depression recurrence in community-dwelling older adults: a prospective study. Am J Psychiatry (2008) 1.38
Low levels of circulating inflammatory cytokines--do they affect human brain functions? Brain Behav Immun (2002) 1.38
Fatigue and gene expression in human leukocytes: increased NF-κB and decreased glucocorticoid signaling in breast cancer survivors with persistent fatigue. Brain Behav Immun (2010) 1.36
Cytokine gene polymorphisms and fatigue in breast cancer survivors: early findings. Brain Behav Immun (2008) 1.36
The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration. Behav Brain Res (2008) 1.36
Cytokine effects on the basal ganglia and dopamine function: the subcortical source of inflammatory malaise. Front Neuroendocrinol (2012) 1.35
Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: a small randomized controlled trial. Brain Behav Immun (2008) 1.35
A preliminary study of daily interpersonal stress and C-reactive protein levels among adolescents from Latin American and European backgrounds. Psychosom Med (2009) 1.34
Hepatitis C infection, antiviral treatment and mental health: a European expert consensus statement. J Hepatol (2012) 1.32
Sex differences in monocyte expression of IL-6: role of autonomic mechanisms. Am J Physiol Regul Integr Comp Physiol (2007) 1.31
Cytokines and glucocorticoid receptor signaling. Relevance to major depression. Ann N Y Acad Sci (2009) 1.30
IFN-alpha-induced motor slowing is associated with increased depression and fatigue in patients with chronic hepatitis C. Brain Behav Immun (2008) 1.30
Degenerating synaptic boutons in prion disease: microglia activation without synaptic stripping. Am J Pathol (2009) 1.29
Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms. Psychoneuroendocrinology (2013) 1.29
Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals? J Affect Disord (2009) 1.28
Social-evaluative threat and proinflammatory cytokine regulation: an experimental laboratory investigation. Psychol Sci (2009) 1.28
Interleukin-1 antagonizes morphine analgesia and underlies morphine tolerance. Pain (2005) 1.27
Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study. Biol Psychiatry (2008) 1.27
Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse. Biol Psychiatry (2004) 1.26
Depression, C-reactive protein and two-year major adverse cardiac events in men after acute coronary syndromes. Biol Psychiatry (2007) 1.21
Cytokine genetic variations and fatigue among patients with breast cancer. J Clin Oncol (2013) 1.21
Gender, obesity and repeated elevation of C-reactive protein: data from the CARDIA cohort. PLoS One (2012) 1.20
Tai Chi Chih acutely decreases sympathetic nervous system activity in older adults. J Gerontol A Biol Sci Med Sci (2006) 1.20
Complementary use of tai chi chih augments escitalopram treatment of geriatric depression: a randomized controlled trial. Am J Geriatr Psychiatry (2011) 1.20
Inflammation selectively enhances amygdala activity to socially threatening images. Neuroimage (2011) 1.19
Intrahippocampal transplantation of transgenic neural precursor cells overexpressing interleukin-1 receptor antagonist blocks chronic isolation-induced impairment in memory and neurogenesis. Neuropsychopharmacology (2007) 1.18
Cytokine-induced changes in mood and behaviour: implications for 'depression due to a general medical condition', immunotherapy and antidepressive treatment. Int J Neuropsychopharmacol (2002) 1.18
Effects of antidepressants on cytokine production and actions. Brain Behav Immun (2002) 1.16
Cholinergic status modulations in human volunteers under acute inflammation. J Mol Med (Berl) (2007) 1.15
Abnormal nocturnal melatonin secretion and disordered sleep in abstinent alcoholics. Biol Psychiatry (2003) 1.15