Programmed cell death.

Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology. Toxicol Sci (2008) 2.49

Photo-inducible cell ablation in Caenorhabditis elegans using the genetically encoded singlet oxygen generating protein miniSOG. Proc Natl Acad Sci U S A (2012) 1.72

Meiotic errors activate checkpoints that improve gamete quality without triggering apoptosis in male germ cells. Curr Biol (2010) 1.67

Apoptosis maintains oocyte quality in aging Caenorhabditis elegans females. PLoS Genet (2008) 1.38

C. elegans outside the Petri dish. Elife (2015) 1.21

Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell. J Cell Biol (2012) 1.13

GLD-2/RNP-8 cytoplasmic poly(A) polymerase is a broad-spectrum regulator of the oogenesis program. Proc Natl Acad Sci U S A (2010) 1.10

Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans. Pediatr Res (2009) 1.07

Apoptotic regulators promote cytokinetic midbody degradation in C. elegans. J Cell Biol (2012) 0.97

CED-3 caspase acts with miRNAs to regulate non-apoptotic gene expression dynamics for robust development in C. elegans. Elife (2014) 0.97

A shift to organismal stress resistance in programmed cell death mutants. PLoS Genet (2013) 0.89

You are what you eat: multifaceted functions of autophagy during C. elegans development. Cell Res (2013) 0.89

Autophagy genes function in apoptotic cell corpse clearance during C. elegans embryonic development. Autophagy (2012) 0.87

Apoptotic engulfment pathway and schizophrenia. PLoS One (2009) 0.86

The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans. Cell Death Differ (2011) 0.85

Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2. PLoS Genet (2009) 0.83

Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans. Front Genet (2012) 0.82

Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons. Cell Death Differ (2010) 0.81

Apoptosis in C. elegans: lessons for cancer and immunity. Front Cell Infect Microbiol (2013) 0.81

Stereotyped distribution of midbody remnants in early C. elegans embryos requires cell death genes and is dispensable for development. Cell Res (2013) 0.80

Small DNA pieces in C. elegans are intermediates of DNA fragmentation during apoptosis. PLoS One (2010) 0.79

Transcriptional regulation of gene expression in C. elegans. WormBook (2013) 0.79

An intestinal microRNA modulates the homeostatic adaptation to chronic oxidative stress in C. elegans. Aging (Albany NY) (2016) 0.75

Cell death machinery makes life more robust. Elife (2014) 0.75

Autonomous and non-autonomous roles of DNase II during cell death in C. elegans embryos. Biosci Rep (2015) 0.75

Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways. PLoS One (2016) 0.75

Developmental decisions: balancing genetics and the environment by C. elegans. Cell Cycle (2012) 0.75

Novel functions for the RNA-binding protein ETR-1 in Caenorhabditis elegans reproduction and engulfment of germline apoptotic cell corpses. Dev Biol (2017) 0.75

Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease. Science (2010) 2.66

Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science (2002) 2.36

Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12. Science (2003) 2.20

Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature (2005) 2.08

Role of C. elegans TAT-1 protein in maintaining plasma membrane phosphatidylserine asymmetry. Science (2008) 1.93

The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease. Crit Rev Biochem Mol Biol (2009) 1.71

C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1. Nat Cell Biol (2007) 1.63

Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9. Mol Cell (2008) 1.61

Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks. EMBO Rep (2005) 1.56

CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation. EMBO J (2003) 1.45

Functional genomic analysis of apoptotic DNA degradation in C. elegans. Mol Cell (2003) 1.41

Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases. Curr Opin Cell Biol (2004) 1.40

Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor. Nat Cell Biol (2010) 1.24

Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4. Mol Cell (2004) 1.23

Cuts can kill: the roles of apoptotic nucleases in cell death and animal development. Chromosoma (2006) 1.22

Programmed cell clearance: molecular regulation of the elimination of apoptotic cell corpses and its role in the resolution of inflammation. Biochem Biophys Res Commun (2010) 1.16

Control of sex-specific apoptosis in C. elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho. Genes Dev (2007) 1.09

Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3. Nat Struct Mol Biol (2008) 1.06

Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction. Proc Natl Acad Sci U S A (2012) 1.03

The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans. Nat Chem Biol (2006) 1.02

Elimination of paternal mitochondria through the lysosomal degradation pathway in C. elegans. Cell Res (2011) 1.01

CED-1, CED-7, and TTR-52 regulate surface phosphatidylserine expression on apoptotic and phagocytic cells. Curr Biol (2012) 0.98

MARCKS-ED peptide as a curvature and lipid sensor. ACS Chem Biol (2012) 0.97

To live or die by the sword: the regulation of apoptosis by the proteasome. Dev Cell (2004) 0.96

Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalization. Nat Commun (2013) 0.96

Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation. Mol Cell Biol (2008) 0.90

Somatic sex determination in Caenorhabditis elegans is modulated by SUP-26 repression of tra-2 translation. Proc Natl Acad Sci U S A (2010) 0.88

The roles and acting mechanism of Caenorhabditis elegans DNase II genes in apoptotic dna degradation and development. PLoS One (2009) 0.85

Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2012) 0.85

Fat(al) attraction: oxidized lipids act as "eat-me" signals. HFSP J (2007) 0.83

RNA aptamers targeting the cell death inhibitor CED-9 induce cell killing in Caenorhabditis elegans. J Biol Chem (2006) 0.83

Cell death specification in C. elegans. Cell Cycle (2008) 0.83

SKR-1, a homolog of Skp1 and a member of the SCF(SEL-10) complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans. Dev Biol (2008) 0.83

Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans. J Biol Chem (2012) 0.81

Bcl-2 proteins EGL-1 and CED-9 do not regulate mitochondrial fission or fusion in Caenorhabditis elegans. Curr Biol (2009) 0.81

Methods for studying programmed cell death in C. elegans. Methods Cell Biol (2012) 0.79

Identification of CED-3 substrates by a yeast-based screening method. Mol Biotechnol (2004) 0.78

Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities. ChemMedChem (2012) 0.77

A class of benzenoid chemicals suppresses apoptosis in C. elegans. Chembiochem (2006) 0.76

Dicing up chromosomes: the unexpected role of Dicer in apoptosis. Cell Cycle (2010) 0.76

Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells. Cell Cycle (2015) 0.75

Caspase protocols in Caenorhabditis elegans. Methods Mol Biol (2014) 0.75

Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem (2022) 0.75