Published in Elife on December 30, 2014
In vivo CaspaseTracker biosensor system for detecting anastasis and non-apoptotic caspase activity. Sci Rep (2015) 0.92
Makorin ortholog LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans. Development (2016) 0.77
Evolution of caspase-mediated cell death and differentiation: twins separated at birth. Cell Death Differ (2017) 0.76
Caspase-dependent non-apoptotic processes in development. Cell Death Differ (2017) 0.76
Changes in apoptotic microRNA and mRNA expression profiling in Caenorhabditis elegans during the Shenzhou-8 mission. J Radiat Res (2015) 0.75
In Vivo Biosensor Tracks Non-apoptotic Caspase Activity in Drosophila. J Vis Exp (2016) 0.75
Cell death machinery makes life more robust. Elife (2014) 0.75
Post-transcriptional control of executioner caspases by RNA-binding proteins. Genes Dev (2016) 0.75
Discovery of small molecule inhibitors for the C. elegans caspase CED-3 by high-throughput screening. Biochem Biophys Res Commun (2017) 0.75
RNA Binding Protein Vigilin Collaborates with miRNAs To Regulate Gene Expression for Caenorhabditis elegans Larval Development. G3 (Bethesda) (2017) 0.75
Caenorhabditis elegans: An important tool for dissecting microRNA functions. Biomed Genet Genom (2016) 0.75
Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development. Dev Cell (2017) 0.75
Clustal W and Clustal X version 2.0. Bioinformatics (2007) 126.47
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87
The functions of animal microRNAs. Nature (2004) 64.85
The Pfam protein families database. Nucleic Acids Res (2011) 33.46
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev Biol (1977) 19.51
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature (2000) 15.98
InterPro in 2011: new developments in the family and domain prediction database. Nucleic Acids Res (2011) 13.45
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet (2004) 12.97
The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell (1997) 12.87
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene (2001) 11.09
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell (1993) 10.35
Biological robustness. Nat Rev Genet (2004) 9.98
Control of developmental timing by micrornas and their targets. Annu Rev Cell Dev Biol (2002) 7.91
Heterochronic mutants of the nematode Caenorhabditis elegans. Science (1984) 6.85
The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell (2005) 5.90
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res (2004) 5.81
Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. Dev Biol (2002) 5.75
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet (2007) 5.33
Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell (2007) 4.22
A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans. Cell (1989) 4.03
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. Mol Cell (2005) 3.97
Formation, regulation and evolution of Caenorhabditis elegans 3'UTRs. Nature (2010) 3.87
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC. Nat Struct Mol Biol (2012) 3.42
Lin28: A microRNA regulator with a macro role. Cell (2010) 3.39
The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev Biol (1990) 3.11
The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch. Nature (1989) 3.03
Many families of C. elegans microRNAs are not essential for development or viability. Curr Biol (2010) 2.90
Control of developmental timing in Caenorhabditis elegans. Curr Opin Genet Dev (2000) 2.84
Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell. Dev Biol (1996) 2.68
Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease. Science (2010) 2.66
A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans. Nature (1987) 2.43
A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature (2013) 2.34
The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegans. Cell (2014) 2.12
GW182 family proteins are crucial for microRNA-mediated gene silencing. Trends Cell Biol (2007) 2.06
Loss of individual microRNAs causes mutant phenotypes in sensitized genetic backgrounds in C. elegans. Curr Biol (2010) 2.02
Temporal pattern formation by heterochronic genes. Annu Rev Genet (1997) 1.90
The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease. Genes Dev (1996) 1.89
Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities. Genes Dev (1996) 1.77
A whole-genome RNAi Screen for C. elegans miRNA pathway genes. Curr Biol (2007) 1.77
Robustness and evolution: concepts, insights and challenges from a developmental model system. Heredity (Edinb) (2006) 1.75
NUC-1, a caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis. Genes Dev (2000) 1.63
The N-end rule pathway: emerging functions and molecular principles of substrate recognition. Nat Rev Mol Cell Biol (2011) 1.62
fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen. Genes Dev (2002) 1.60
Caenorhabditis elegans dpy-5 is a cuticle procollagen processed by a proprotein convertase. Cell Mol Life Sci (2006) 1.52
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2009) 1.39
RNAi screens in Caenorhabditis elegans in a 96-well liquid format and their application to the systematic identification of genetic interactions. Nat Protoc (2006) 1.37
The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans. PLoS Biol (2012) 1.32
A gut-to-pharynx/tail switch in embryonic expression of the Caenorhabditis elegans ges-1 gene centers on two GATA sequences. Dev Biol (1995) 1.32
Programmed cell death. WormBook (2005) 1.29
Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans. EMBO J (2006) 1.29
Charting the genetic interaction map of a cell. Curr Opin Biotechnol (2010) 1.28
Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs. RNA (2013) 1.20
microRNAs play critical roles in the survival and recovery of Caenorhabditis elegans from starvation-induced L1 diapause. Proc Natl Acad Sci U S A (2011) 1.19
miRNAs give worms the time of their lives: small RNAs and temporal control in Caenorhabditis elegans. Dev Dyn (2010) 1.14
Systematic analysis of dynamic miRNA-target interactions during C. elegans development. Development (2009) 1.14
Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation. J Biol Chem (2011) 1.12
Effect of life history on microRNA expression during C. elegans development. RNA (2011) 1.11
Caenorhabditis elegans as a model for stem cell biology. Dev Dyn (2010) 1.11
A developmental timing switch promotes axon outgrowth independent of known guidance receptors. PLoS Genet (2010) 1.04
DAF-12 regulates a connected network of genes to ensure robust developmental decisions. PLoS Genet (2011) 1.02
Establishing a blueprint for CED-3-dependent killing through identification of multiple substrates for this protease. J Biol Chem (2007) 1.01
Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalization. Nat Commun (2013) 0.96
Systematic analysis of tissue-restricted miRISCs reveals a broad role for microRNAs in suppressing basal activity of the C. elegans pathogen response. Mol Cell (2012) 0.96
DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans. Genetics (2007) 0.96
Developmental transitions in C. elegans larval stages. Curr Top Dev Biol (2013) 0.94
Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development. Genes Dev (2006) 0.93
Inhibition of CPP32 blocks surface IgM-mediated apoptosis and D4-GDI cleavage in human BL60 Burkitt lymphoma cells. Eur J Immunol (1998) 0.91
Cell death specification in C. elegans. Cell Cycle (2008) 0.83
Functional analysis of neuronal microRNAs in Caenorhabditis elegans dauer formation by combinational genetics and Neuronal miRISC immunoprecipitation. PLoS Genet (2013) 0.81
Analysis of programmed cell death in the nematode Caenorhabditis elegans. Methods Enzymol (2000) 0.80