Published in Free Radic Biol Med on November 17, 2007
Wound healing essentials: let there be oxygen. Wound Repair Regen (2009) 2.31
Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds. Proc Natl Acad Sci U S A (2010) 2.11
Redox control of the cell cycle in health and disease. Antioxid Redox Signal (2009) 1.72
Characterization of the acute temporal changes in excisional murine cutaneous wound inflammation by screening of the wound-edge transcriptome. Physiol Genomics (2008) 1.57
Heme oxygenase-1 accelerates cutaneous wound healing in mice. PLoS One (2009) 1.23
Topical oxygen therapy induces vascular endothelial growth factor expression and improves closure of clinically presented chronic wounds. Clin Exp Pharmacol Physiol (2008) 1.06
Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth. Am J Physiol Heart Circ Physiol (2009) 0.94
Effects of hydrogen peroxide on wound healing in mice in relation to oxidative damage. PLoS One (2012) 0.93
Ulcerative dermatitis in C57BL/6 mice exhibits an oxidative stress response consistent with normal wound healing. Comp Med (2012) 0.89
Whole-body transcriptome of selectively bred, resistant-, control-, and susceptible-line rainbow trout following experimental challenge with Flavobacterium psychrophilum. Front Genet (2015) 0.88
Vasculoprotective effects of combined endothelial progenitor cells and mesenchymal stem cells in diabetic wound care: their potential role in decreasing wound-oxidative stress. Biomed Res Int (2013) 0.84
ICAM-1 cytoplasmic tail regulates endothelial glutathione synthesis through a NOX4/PI3-kinase-dependent pathway. Free Radic Biol Med (2010) 0.83
Comparative transcriptomic profiling of hydrogen peroxide signaling networks in zebrafish and human keratinocytes: Implications toward conservation, migration and wound healing. Sci Rep (2016) 0.77
The world as viewed by and with unpaired electrons. J Magn Reson (2012) 0.75
Rac2 Functions in Both Neutrophils and Macrophages To Mediate Motility and Host Defense in Larval Zebrafish. J Immunol (2016) 0.75
Percutaneous re-circulating isolated limb perfusion of gentamicin in a large animal model: targeted delivery of gentamicin to limb. Am J Transl Res (2013) 0.75
Effect of astaxanthin on cutaneous wound healing. Clin Cosmet Investig Dermatol (2017) 0.75
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med (1991) 16.01
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med (2001) 11.92
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science (1997) 6.50
Cell transformation by the superoxide-generating oxidase Mox1. Nature (1999) 6.23
Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med (2000) 5.22
Hydrogen peroxide: a signaling messenger. Antioxid Redox Signal (2006) 4.19
Regulation of NADPH oxidases: the role of Rac proteins. Circ Res (2006) 3.16
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation. Proc Natl Acad Sci U S A (2000) 2.26
General principles of wound healing. Surg Clin North Am (1997) 2.04
Dermal wound healing is subject to redox control. Mol Ther (2005) 1.89
Oxidant-induced vascular endothelial growth factor expression in human keratinocytes and cutaneous wound healing. J Biol Chem (2002) 1.81
Spin trapping of superoxide. Mol Pharmacol (1979) 1.73
Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. J Cell Sci (2006) 1.70
Free radicals and phagocytic cells. FASEB J (1995) 1.65
Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles. J Immunol (2004) 1.55
Oxygen, oxidants, and antioxidants in wound healing: an emerging paradigm. Ann N Y Acad Sci (2002) 1.54
Revisiting the essential role of oxygen in wound healing. Am J Surg (2003) 1.52
The general case for redox control of wound repair. Wound Repair Regen (2003) 1.24
Skin repair and scar formation: the central role of TGF-beta. Expert Rev Mol Med (2003) 1.21
A real-time electrochemical technique for measurement of cellular hydrogen peroxide generation and consumption: evaluation in human polymorphonuclear leukocytes. Free Radic Biol Med (2001) 1.11
Energy metabolism of experimental wounds at various oxygen environments. Ann Surg (1975) 1.03
Color subtractive-computer-assisted image analysis for quantification of cutaneous nerves in a diabetic mouse model. J Histochem Cytochem (2001) 1.03
In vivo EPR imaging of the distribution and metabolism of nitroxide radicals in human skin. J Magn Reson (2001) 1.00
Glutathione-mediated formation of oxygen free radicals by the major metabolite of oltipraz. Chem Res Toxicol (2005) 0.93
Quantitative measurement of superoxide generation and oxygen consumption from leukocytes using electron paramagnetic resonance spectroscopy. Anal Biochem (1998) 0.91
Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen (2009) 7.29
MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue. Cardiovasc Res (2009) 4.88
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science (2004) 4.81
MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab (2009) 3.30
A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal. Nature (2002) 2.86
Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation (2003) 2.68
Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels. Cancer Res (2002) 2.56
Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition. Circulation (2008) 2.37
S-glutathionylation uncouples eNOS and regulates its cellular and vascular function. Nature (2010) 2.35
Nitrate and nitrite in biology, nutrition and therapeutics. Nat Chem Biol (2009) 2.29
Redox modification of ryanodine receptors contributes to sarcoplasmic reticulum Ca2+ leak in chronic heart failure. Circ Res (2008) 2.24
Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue. Am J Physiol Regul Integr Comp Physiol (2011) 2.23
Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells. Am J Physiol Lung Cell Mol Physiol (2002) 2.18
Novel particulate spin probe for targeted determination of oxygen in cells and tissues. Free Radic Biol Med (2003) 2.18
Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds. Proc Natl Acad Sci U S A (2010) 2.11
Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function. J Biol Chem (2006) 2.01
Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK. Arterioscler Thromb Vasc Biol (2008) 1.97
Macrophage dysfunction impairs resolution of inflammation in the wounds of diabetic mice. PLoS One (2010) 1.95
Dermal wound healing is subject to redox control. Mol Ther (2005) 1.89
Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall. Am J Physiol Heart Circ Physiol (2008) 1.88
Transcriptome-wide analysis of blood vessels laser captured from human skin and chronic wound-edge tissue. Proc Natl Acad Sci U S A (2007) 1.87
Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase. J Biol Chem (2008) 1.82
Oxidant-induced vascular endothelial growth factor expression in human keratinocytes and cutaneous wound healing. J Biol Chem (2002) 1.81
Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4. Proc Natl Acad Sci U S A (2007) 1.78
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies. Br J Pharmacol (2003) 1.77
Myocardial oxygenation and functional recovery in infarct rat hearts transplanted with mesenchymal stem cells. Am J Physiol Heart Circ Physiol (2009) 1.74
In vivo atherosclerotic plaque characterization using magnetic susceptibility distinguishes symptom-producing plaques. JACC Cardiovasc Imaging (2008) 1.69
Mitochondrial complex II in the post-ischemic heart: oxidative injury and the role of protein S-glutathionylation. J Biol Chem (2007) 1.68
Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology. Cardiovasc Res (2011) 1.65
Cellular protection with proanthocyanidins derived from grape seeds. Ann N Y Acad Sci (2002) 1.63
Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR. Magn Reson Med (2005) 1.63
Tocotrienols: Vitamin E beyond tocopherols. Life Sci (2006) 1.61
Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration. J Biol Chem (2003) 1.61
Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice. Cancer Res (2011) 1.61
EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression. J Biol Chem (2007) 1.59
Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice. Circ Res (2006) 1.58
Characterization of the acute temporal changes in excisional murine cutaneous wound inflammation by screening of the wound-edge transcriptome. Physiol Genomics (2008) 1.57
Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages. Cancer Res (2009) 1.57
Neuroprotective properties of the natural vitamin E alpha-tocotrienol. Stroke (2005) 1.56
Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation. Blood (2006) 1.56
miR-210: the master hypoxamir. Microcirculation (2012) 1.56
Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme. J Biol Chem (2008) 1.55
Oxygen, oxidants, and antioxidants in wound healing: an emerging paradigm. Ann N Y Acad Sci (2002) 1.54
Trityl radicals as persistent dual function pH and oxygen probes for in vivo electron paramagnetic resonance spectroscopy and imaging: concept and experiment. J Am Chem Soc (2007) 1.53
Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury. FEBS Lett (2005) 1.53
miR-200b targets Ets-1 and is down-regulated by hypoxia to induce angiogenic response of endothelial cells. J Biol Chem (2010) 1.53
Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. Mutat Res (2003) 1.53
The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival. Am J Respir Cell Mol Biol (2006) 1.52
Revisiting the essential role of oxygen in wound healing. Am J Surg (2003) 1.52
Cardiac mitochondria and reactive oxygen species generation. Circ Res (2014) 1.51
Endothelium-derived nitric oxide regulates postischemic myocardial oxygenation and oxygen consumption by modulation of mitochondrial electron transport. Circulation (2005) 1.51
Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity. Cancer Res (2008) 1.50
Redox signals in wound healing. Biochim Biophys Acta (2008) 1.49
Large-scale synthesis of a persistent trityl radical for use in biomedical EPR applications and imaging. Bioorg Med Chem Lett (2007) 1.48
Theory, instrumentation, and applications of electron paramagnetic resonance oximetry. Chem Rev (2010) 1.48
Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation. J Biol Chem (2004) 1.48
MicroRNA in ischemic stroke etiology and pathology. Physiol Genomics (2010) 1.48
Hypoxic preconditioning induces the expression of prosurvival and proangiogenic markers in mesenchymal stem cells. Am J Physiol Cell Physiol (2010) 1.47
Oxygen, the lead actor in the pathophysiologic drama: enactment of the trinity of normoxia, hypoxia, and hyperoxia in disease and therapy. Antioxid Redox Signal (2007) 1.47
Evidence for the involvement of miRNA in redox regulated angiogenic response of human microvascular endothelial cells. Arterioscler Thromb Vasc Biol (2008) 1.46
Fast EPR imaging at 300 MHz using spinning magnetic field gradients. J Magn Reson (2004) 1.45
Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms. Antioxid Redox Signal (2007) 1.45
Hyperbaric oxygen therapy ameliorates stress-impaired dermal wound healing. Brain Behav Immun (2005) 1.44
In vivo imaging of changes in tumor oxygenation during growth and after treatment. Magn Reson Med (2007) 1.42
Tocotrienols in health and disease: the other half of the natural vitamin E family. Mol Aspects Med (2007) 1.41