Richard Killick

Author PubWeight™ 32.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Arch Gen Psychiatry 2010 3.64
2 The GSK3 hypothesis of Alzheimer's disease. J Neurochem 2007 3.16
3 Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci U S A 2011 1.58
4 Glycogen synthase kinase-3 inhibition is integral to long-term potentiation. Eur J Neurosci 2007 1.50
5 Schizophrenia as a GSK-3 dysregulation disorder. Trends Neurosci 2007 1.42
6 Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease. Neuromolecular Med 2004 1.26
7 Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. PLoS Genet 2010 1.23
8 E1A activates transcription of p73 and Noxa to induce apoptosis. J Biol Chem 2004 1.14
9 Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system. Eur J Neurosci 2008 1.12
10 p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells. Neurosci Lett 2007 1.08
11 Plasma biomarkers of brain atrophy in Alzheimer's disease. PLoS One 2011 1.06
12 Plasma transthyretin as a candidate marker for Alzheimer's disease. J Alzheimers Dis 2012 0.99
13 GSK3alpha exhibits beta-catenin and tau directed kinase activities that are modulated by Wnt. Eur J Neurosci 2006 0.97
14 Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or apoptin. Cell Cycle 2007 0.93
15 A structural switch of presenilin 1 by glycogen synthase kinase 3beta-mediated phosphorylation regulates the interaction with beta-catenin and its nuclear signaling. J Biol Chem 2007 0.92
16 TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones. J Neurochem 2006 0.91
17 Alzheimer-associated C allele of the promoter polymorphism -22C>T causes a critical neuron-specific decrease of presenilin 1 expression. Hum Mol Genet 2003 0.89
18 Positional pathway screen of wnt signaling genes in schizophrenia: association with DKK4. Biol Psychiatry 2007 0.89
19 TAp73alpha induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism. Neurosci Lett 2006 0.88
20 Wnt3a induces exosome secretion from primary cultured rat microglia. BMC Neurosci 2012 0.87
21 The Notch-1 intracellular domain is found in sub-nuclear bodies in SH-SY5Y neuroblastomas and in primary cortical neurons. Neurosci Lett 2007 0.84
22 β-Amyloid precursor protein and tau protein levels are differently regulated in human cerebellum compared to brain regions vulnerable to Alzheimer's type neurodegeneration. Neurosci Lett 2010 0.84
23 Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. J Biol Chem 2013 0.82
24 Toward an understanding of cochlear homeostasis: the impact of location and the role of OCP1 and OCP2. Acta Otolaryngol 2003 0.81
25 An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum. J Cell Sci 2014 0.79
26 Oligomeric amyloid-β peptide affects the expression of genes involved in steroid and lipid metabolism in primary neurons. Neurochem Int 2012 0.79
27 Transcriptomic profiles of Wnt3a and insulin in primary cultured rat cortical neurones. J Neurochem 2011 0.78
28 Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. Neurobiol Aging 2012 0.75