Published in Mol Biol Cell on December 19, 2007
Ciliopathies with skeletal anomalies and renal insufficiency due to mutations in the IFT-A gene WDR19. Am J Hum Genet (2011) 1.98
The Trypanosoma brucei flagellum: moving parasites in new directions. Annu Rev Microbiol (2009) 1.66
Intraflagellar transport particle size scales inversely with flagellar length: revisiting the balance-point length control model. J Cell Biol (2009) 1.62
Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components. Proc Natl Acad Sci U S A (2011) 1.58
Flagellar membrane localization via association with lipid rafts. J Cell Sci (2009) 1.49
An IFT-A protein is required to delimit functionally distinct zones in mechanosensory cilia. Curr Biol (2008) 1.46
Independent analysis of the flagellum surface and matrix proteomes provides insight into flagellum signaling in mammalian-infectious Trypanosoma brucei. Mol Cell Proteomics (2011) 1.44
Soluble levels of cytosolic tubulin regulate ciliary length control. Mol Biol Cell (2011) 1.41
Novel bilobe components in Trypanosoma brucei identified using proximity-dependent biotinylation. Eukaryot Cell (2012) 1.39
Mainzer-Saldino syndrome is a ciliopathy caused by IFT140 mutations. Am J Hum Genet (2012) 1.38
Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane. J Cell Sci (2009) 1.24
Tubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility. J Biol Chem (2011) 1.19
Disruption of IFT complex A causes cystic kidneys without mitotic spindle misorientation. J Am Soc Nephrol (2012) 1.16
The flagellum of Trypanosoma brucei: new tricks from an old dog. Int J Parasitol (2008) 1.15
Motility and more: the flagellum of Trypanosoma brucei. Nat Rev Microbiol (2014) 1.11
Subunit interactions and organization of the Chlamydomonas reinhardtii intraflagellar transport complex A proteins. J Biol Chem (2011) 1.11
Combined NGS approaches identify mutations in the intraflagellar transport gene IFT140 in skeletal ciliopathies with early progressive kidney Disease. Hum Mutat (2013) 1.07
Morphology of the trypanosome bilobe, a novel cytoskeletal structure. Eukaryot Cell (2012) 1.04
Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics. Mol Cell Proteomics (2014) 1.03
Cilia and Diseases. Bioscience (2014) 1.02
TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella. Elife (2014) 1.02
Intraflagellar transport at a glance. J Cell Sci (2009) 1.02
Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor. J Biol Chem (2011) 0.99
Total internal reflection fluorescence (TIRF) microscopy of Chlamydomonas flagella. Methods Cell Biol (2009) 0.99
High-resolution crystal structure and in vivo function of a kinesin-2 homologue in Giardia intestinalis. Mol Biol Cell (2008) 0.97
Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei. J Struct Biol (2012) 0.96
DYF-1 Is required for assembly of the axoneme in Tetrahymena thermophila. Eukaryot Cell (2009) 0.96
Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex. EMBO J (2016) 0.94
Getting to the heart of intraflagellar transport using Trypanosoma and Chlamydomonas models: the strength is in their differences. Cilia (2013) 0.91
Biochemical analysis of PIFTC3, the Trypanosoma brucei orthologue of nematode DYF-13, reveals interactions with established and putative intraflagellar transport components. Mol Microbiol (2010) 0.91
Dynein-2 affects the regulation of ciliary length but is not required for ciliogenesis in Tetrahymena thermophila. Mol Biol Cell (2008) 0.90
Kinesin 9 family members perform separate functions in the trypanosome flagellum. J Cell Biol (2009) 0.90
The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport. Elife (2014) 0.90
The kinesin superfamily protein KIF17: one protein with many functions. Biomol Concepts (2012) 0.89
More than meets the eye: understanding Trypanosoma brucei morphology in the tsetse. Front Cell Infect Microbiol (2013) 0.89
Mutations in human IFT140 cause non-syndromic retinal degeneration. Hum Genet (2015) 0.88
Approaches for functional analysis of flagellar proteins in African trypanosomes. Methods Cell Biol (2009) 0.88
Trafficking and release of Leishmania metacyclic HASPB on macrophage invasion. Cell Microbiol (2012) 0.88
Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes. Proc Natl Acad Sci U S A (2016) 0.86
The role of the Kinesin-13 family protein TbKif13-2 in flagellar length control of Trypanosoma brucei. Mol Biochem Parasitol (2010) 0.83
KHARON1 mediates flagellar targeting of a glucose transporter in Leishmania mexicana and is critical for viability of infectious intracellular amastigotes. J Biol Chem (2013) 0.83
Efficient live fluorescence imaging of intraflagellar transport in mammalian primary cilia. Methods Cell Biol (2015) 0.82
Basal body multipotency and axonemal remodelling are two pathways to a 9+0 flagellum. Nat Commun (2015) 0.82
The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host. Mol Microbiol (2013) 0.81
Imaging intraflagellar transport in mammalian primary cilia. Methods Cell Biol (2009) 0.81
Rab23 is a flagellar protein in Trypanosoma brucei. BMC Res Notes (2011) 0.80
The intraflagellar transport dynein complex of trypanosomes is made of a heterodimer of dynein heavy chains and of light and intermediate chains of distinct functions. Mol Biol Cell (2014) 0.80
Isolation of intraflagellar transport trains. Cytoskeleton (Hoboken) (2013) 0.79
Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm. Mol Biol Cell (2015) 0.78
The eukaryotic flagellum makes the day: novel and unforeseen roles uncovered after post-genomics and proteomics data. Curr Protein Pept Sci (2012) 0.78
An alternative model for the role of RP2 protein in flagellum assembly in the African trypanosome. J Biol Chem (2013) 0.78
Overexpression of S4D mutant of Leishmania donovani ADF/cofilin impairs flagellum assembly by affecting actin dynamics. Eukaryot Cell (2012) 0.77
Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep (2016) 0.77
New insights into the molecular mechanisms of mitosis and cytokinesis in trypanosomes. Int Rev Cell Mol Biol (2014) 0.77
Differential Subcellular Localization of Leishmania Alba-Domain Proteins throughout the Parasite Development. PLoS One (2015) 0.76
Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis. PLoS Genet (2017) 0.75
Trypanosoma brucei FKBP12 differentially controls motility and cytokinesis in procyclic and bloodstream forms. Eukaryot Cell (2012) 0.75
Boarder control on the IFT train. Elife (2014) 0.75
Polyglutamylation: the GLU that makes microtubules sticky. Curr Biol (2010) 0.75
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene (1988) 52.71
A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol (1999) 11.77
The genome of the African trypanosome Trypanosoma brucei. Science (2005) 11.48
Intraflagellar transport. Nat Rev Mol Cell Biol (2002) 10.86
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell (2007) 10.75
Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature (2003) 8.38
Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell (1998) 8.16
Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons. J Cell Biol (1998) 7.22
Proteomic analysis of a eukaryotic cilium. J Cell Biol (2005) 6.54
A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc Natl Acad Sci U S A (1993) 6.50
Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Cell (2004) 5.02
Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters. J Biol Chem (2000) 4.96
The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane. J Cell Biol (1995) 4.78
Flagellar motility is required for the viability of the bloodstream trypanosome. Nature (2006) 4.71
The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly. Mol Biol Cell (2006) 4.18
The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly. J Cell Biol (1999) 3.97
Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles. Curr Biol (2001) 3.58
Two anterograde intraflagellar transport motors cooperate to build sensory cilia on C. elegans neurons. Nat Cell Biol (2004) 3.43
Intraflagellar transport (IFT) cargo: IFT transports flagellar precursors to the tip and turnover products to the cell body. J Cell Biol (2004) 3.30
Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas. Mol Biol Cell (1999) 3.20
Functional genomics of the cilium, a sensory organelle. Curr Biol (2005) 3.11
Transport of a novel complex in the cytoplasmic matrix of Chlamydomonas flagella. Proc Natl Acad Sci U S A (1997) 3.00
Analysis of osm-6, a gene that affects sensory cilium structure and sensory neuron function in Caenorhabditis elegans. Genetics (1998) 2.83
The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations. Philos Trans R Soc Lond B Biol Sci (1989) 2.81
Intraflagellar transport balances continuous turnover of outer doublet microtubules: implications for flagellar length control. J Cell Biol (2001) 2.81
Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans. J Cell Biol (1999) 2.67
The intraflagellar transport machinery of Chlamydomonas reinhardtii. Traffic (2003) 2.56
RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei. Mol Biochem Parasitol (2003) 2.55
Mutations affecting the chemosensory neurons of Caenorhabditis elegans. Genetics (1995) 2.54
The exosome of Trypanosoma brucei. EMBO J (2001) 2.48
Inducible gene expression in trypanosomes mediated by a prokaryotic repressor. Science (1995) 2.42
Assembly of the paraflagellar rod and the flagellum attachment zone complex during the Trypanosoma brucei cell cycle. J Eukaryot Microbiol (1999) 2.30
Movement of motor and cargo along cilia. Nature (1999) 2.21
Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. J Cell Biol (2007) 2.16
Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm. Curr Biol (2003) 2.06
Flagellar length control system: testing a simple model based on intraflagellar transport and turnover. Mol Biol Cell (2004) 2.04
Centrin plays an essential role in microtubule severing during flagellar excision in Chlamydomonas reinhardtii. J Cell Biol (1994) 1.97
Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes. EMBO J (2003) 1.91
Paraflagellar rod is vital for trypanosome motility. Nature (1998) 1.85
Sensory ciliogenesis in Caenorhabditis elegans: assignment of IFT components into distinct modules based on transport and phenotypic profiles. Mol Biol Cell (2007) 1.82
Golgi duplication in Trypanosoma brucei requires Centrin2. Science (2005) 1.80
Conserved and specific functions of axoneme components in trypanosome motility. J Cell Sci (2006) 1.77
A trypanosome structure involved in transmitting cytoplasmic information during cell division. Science (2001) 1.72
Chlamydomonas IFT172 is encoded by FLA11, interacts with CrEB1, and regulates IFT at the flagellar tip. Curr Biol (2005) 1.68
Flagellar motility contributes to cytokinesis in Trypanosoma brucei and is modulated by an evolutionarily conserved dynein regulatory system. Eukaryot Cell (2006) 1.67
Flagellum ontogeny in trypanosomes studied via an inherited and regulated RNA interference system. J Cell Sci (2000) 1.65
Dissecting the molecular mechanisms of intraflagellar transport in chlamydomonas. Curr Biol (2006) 1.63
Drosophila KAP interacts with the kinesin II motor subunit KLP64D to assemble chordotonal sensory cilia, but not sperm tails. Curr Biol (2003) 1.46
The flagella connector of Trypanosoma brucei: an unusual mobile transmembrane junction. J Cell Sci (2004) 1.43
The WD repeat-containing protein IFTA-1 is required for retrograde intraflagellar transport. Mol Biol Cell (2006) 1.42
Efficiency and specificity of RNA interference generated by intra- and intermolecular double stranded RNA in Trypanosoma brucei. Mol Biochem Parasitol (2003) 1.42
Intraflagellar transport (IFT) during assembly and disassembly of Chlamydomonas flagella. J Cell Biol (2005) 1.37
More than one way to build a flagellum: comparative genomics of parasitic protozoa. Curr Biol (2004) 1.36
Protein transport and flagellum assembly dynamics revealed by analysis of the paralysed trypanosome mutant snl-1. J Cell Sci (1999) 1.36
Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella. J Cell Sci (2007) 1.33
The molecular identities of the Caenorhabditis elegans intraflagellar transport genes dyf-6, daf-10 and osm-1. Genetics (2006) 1.30
Trypanosome IFT mutants provide insight into the motor location for mobility of the flagella connector and flagellar membrane formation. J Cell Sci (2006) 1.29
NIMA-related kinase TbNRKC is involved in basal body separation in Trypanosoma brucei. J Cell Sci (2006) 1.28
Basal body positioning is controlled by flagellum formation in Trypanosoma brucei. PLoS One (2007) 1.28
Centrin1 is required for organelle segregation and cytokinesis in Trypanosoma brucei. Mol Biol Cell (2007) 1.25
The dyf-3 gene encodes a novel protein required for sensory cilium formation in Caenorhabditis elegans. J Mol Biol (2004) 1.25
Flagellar morphogenesis: protein targeting and assembly in the paraflagellar rod of trypanosomes. Mol Cell Biol (1999) 1.23
Inside and outside of the trypanosome flagellum:a multifunctional organelle. Microbes Infect (2000) 1.19
The flagellum of trypanosomes. Int Rev Cytol (2005) 1.10
Caenorhabditis elegans DYF-2, an orthologue of human WDR19, is a component of the intraflagellar transport machinery in sensory cilia. Mol Biol Cell (2006) 1.08
Hypoxia regulates assembly of cilia in suppressors of Tetrahymena lacking an intraflagellar transport subunit gene. Mol Biol Cell (2003) 1.07
The paraflagellar rod of kinetoplastida: solved and unsolved questions. Parasitol Today (1996) 1.06
The two cytoplasmic dynein-2 isoforms in Leishmania mexicana perform separate functions. Mol Biochem Parasitol (2005) 0.91
New insights into the assembly of the periaxonemal structures in mammalian spermatozoa. Biol Reprod (2003) 0.84
Characterization of a coiled coil protein present in the basal body of Trypanosoma brucei. J Cell Sci (1999) 0.84
Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science (2013) 2.25
Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes. EMBO J (2003) 1.91
Conserved and specific functions of axoneme components in trypanosome motility. J Cell Sci (2006) 1.77
Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia. Am J Hum Genet (2009) 1.65
The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia. J Cell Sci (2010) 1.58
A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei. Protist (2007) 1.44
TbAGO1, an argonaute protein required for RNA interference, is involved in mitosis and chromosome segregation in Trypanosoma brucei. BMC Biol (2003) 1.43
Efficiency and specificity of RNA interference generated by intra- and intermolecular double stranded RNA in Trypanosoma brucei. Mol Biochem Parasitol (2003) 1.42
A new asymmetric division contributes to the continuous production of infective trypanosomes in the tsetse fly. Development (2012) 1.36
Proteomic analysis identifies novel proteins of the Maurer's clefts, a secretory compartment delivering Plasmodium falciparum proteins to the surface of its host cell. Mol Cell Proteomics (2005) 1.29
Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity. Proc Natl Acad Sci U S A (2003) 1.28
Basal body positioning is controlled by flagellum formation in Trypanosoma brucei. PLoS One (2007) 1.28
NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions. PLoS Biol (2012) 1.12
1001 model organisms to study cilia and flagella. Biol Cell (2011) 1.12
The flagellum of trypanosomes. Int Rev Cytol (2005) 1.10
Intraflagellar transport proteins cycle between the flagellum and its base. J Cell Sci (2012) 1.09
Flagellum elongation is required for correct structure, orientation and function of the flagellar pocket in Trypanosoma brucei. J Cell Sci (2008) 1.07
The RhopH complex is transferred to the host cell cytoplasm following red blood cell invasion by Plasmodium falciparum. Mol Biochem Parasitol (2008) 1.07
The ciliary pocket: a once-forgotten membrane domain at the base of cilia. Biol Cell (2011) 1.05
The flagellum-mitogen-activated protein kinase connection in Trypanosomatids: a key sensory role in parasite signalling and development? Cell Microbiol (2009) 1.03
ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation. Mol Biol Cell (2011) 1.01
A novel function for the atypical small G protein Rab-like 5 in the assembly of the trypanosome flagellum. J Cell Sci (2009) 1.00
Probiotics for the control of parasites: an overview. J Parasitol Res (2011) 0.99
Flagellar adhesion in Trypanosoma brucei relies on interactions between different skeletal structures in the flagellum and cell body. J Cell Sci (2013) 0.93
Molecular bases of cytoskeleton plasticity during the Trypanosoma brucei parasite cycle. Cell Microbiol (2011) 0.93
Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation. Cell Microbiol (2011) 0.92
Identification of genes required for different stages of dendritic swarming in Bacillus subtilis, with a novel role for phrC. Microbiology (2009) 0.92
Getting to the heart of intraflagellar transport using Trypanosoma and Chlamydomonas models: the strength is in their differences. Cilia (2013) 0.91
Kinesin 9 family members perform separate functions in the trypanosome flagellum. J Cell Biol (2009) 0.90
The Argonaute protein TbAGO1 contributes to large and mini-chromosome segregation and is required for control of RIME retroposons and RHS pseudogene-associated transcripts. Mol Biochem Parasitol (2007) 0.89
More than meets the eye: understanding Trypanosoma brucei morphology in the tsetse. Front Cell Infect Microbiol (2013) 0.89
Functional complementation of RNA interference mutants in trypanosomes. BMC Biotechnol (2005) 0.89
Single-cell analysis in situ in a Bacillus subtilis swarming community identifies distinct spatially separated subpopulations differentially expressing hag (flagellin), including specialized swarmers. Microbiology (2011) 0.88
Forward motility is essential for trypanosome infection in the tsetse fly. Cell Microbiol (2013) 0.86
Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani. Antimicrob Agents Chemother (2012) 0.86
An encapsulated Yersinia pseudotuberculosis is a highly efficient vaccine against pneumonic plague. PLoS Negl Trop Dis (2012) 0.85
Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis. Antimicrob Agents Chemother (2010) 0.85
Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability. PLoS Negl Trop Dis (2010) 0.83
Sequence-specific targeting of IGF-I and IGF-IR genes by camptothecins. FASEB J (2010) 0.81
The peculiarities of flagella in parasitic protozoa. Curr Opin Microbiol (2010) 0.79
The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status. Mol Microbiol (2014) 0.78
Tools for analyzing intraflagellar transport in trypanosomes. Methods Cell Biol (2009) 0.76
[The importance of model organisms to study cilia and flagella biology]. Biol Aujourdhui (2011) 0.76
Trypanosoma brucei FKBP12 differentially controls motility and cytokinesis in procyclic and bloodstream forms. Eukaryot Cell (2012) 0.75
Flagellar kinesins in protists. Future Microbiol (2011) 0.75
Boarder control on the IFT train. Elife (2014) 0.75
What's in that pot o'gold? MLO Med Lab Obs (2006) 0.75
The government wants to know. MLO Med Lab Obs (2006) 0.75
[The flagellum: from cell motility to morphogenesis]. J Soc Biol (2003) 0.75