|
1
|
Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome.
|
Gastroenterology
|
2012
|
6.04
|
|
2
|
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles.
|
J Biol Chem
|
2002
|
2.61
|
|
3
|
Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism.
|
Hepatology
|
2010
|
2.16
|
|
4
|
Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
|
Gastroenterology
|
2008
|
2.06
|
|
5
|
Induction of hepatic ABC transporter expression is part of the PPARalpha-mediated fasting response in the mouse.
|
Gastroenterology
|
2003
|
1.64
|
|
6
|
Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.
|
J Biol Chem
|
2002
|
1.50
|
|
7
|
Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.
|
Gastroenterology
|
2004
|
1.36
|
|
8
|
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux.
|
J Biol Chem
|
2006
|
1.28
|
|
9
|
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction.
|
Am J Physiol Regul Integr Comp Physiol
|
2009
|
1.18
|
|
10
|
Liver X receptor activation restores memory in aged AD mice without reducing amyloid.
|
Neurobiol Aging
|
2009
|
1.06
|
|
11
|
Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice.
|
Hepatology
|
2008
|
1.04
|
|
12
|
Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice.
|
Am J Physiol Gastrointest Liver Physiol
|
2006
|
1.03
|
|
13
|
An increased flux through the glucose 6-phosphate pool in enterocytes delays glucose absorption in Fxr-/- mice.
|
J Biol Chem
|
2009
|
0.99
|
|
14
|
Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.
|
Biochem J
|
2003
|
0.99
|
|
15
|
Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia.
|
J Biol Chem
|
2007
|
0.98
|
|
16
|
Essential fatty acid deficiency in mice is associated with hepatic steatosis and secretion of large VLDL particles.
|
Am J Physiol Gastrointest Liver Physiol
|
2005
|
0.95
|
|
17
|
Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter.
|
J Nutr
|
2006
|
0.94
|
|
18
|
Gene expression profiling in livers of mice after acute inhibition of beta-oxidation.
|
Genomics
|
2007
|
0.92
|
|
19
|
Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration.
|
Hepatology
|
2011
|
0.92
|
|
20
|
Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion.
|
J Lipid Res
|
2007
|
0.90
|
|
21
|
Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor alpha.
|
J Lipid Res
|
2006
|
0.87
|
|
22
|
Lxralpha deficiency hampers the hepatic adaptive response to fasting in mice.
|
J Biol Chem
|
2008
|
0.87
|
|
23
|
Chronic prednisolone treatment reduces hepatic insulin sensitivity while perturbing the fed-to-fasting transition in mice.
|
Endocrinology
|
2010
|
0.85
|
|
24
|
The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion.
|
J Lipid Res
|
2007
|
0.83
|
|
25
|
Alterations in brain cholesterol metabolism in the APPSLxPS1mut mouse, a model for Alzheimer's disease.
|
J Alzheimers Dis
|
2010
|
0.82
|
|
26
|
Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.
|
Hepatology
|
2002
|
0.81
|
|
27
|
Sex-dependent programming of glucose and fatty acid metabolism in mouse offspring by maternal protein restriction.
|
Gend Med
|
2012
|
0.80
|
|
28
|
Bile acid sequestration normalizes plasma cholesterol and reduces atherosclerosis in hypercholesterolemic mice. No additional effect of physical activity.
|
Atherosclerosis
|
2013
|
0.79
|
|
29
|
Two time-point assessment of bile acid kinetics in humans using stable isotopes.
|
Isotopes Environ Health Stud
|
2010
|
0.78
|
|
30
|
Postnatal treatment with dexamethasone perturbs hepatic and cardiac energy metabolism and is associated with a sustained atherogenic plasma lipid profile in suckling rats.
|
Pediatr Res
|
2007
|
0.78
|
|
31
|
Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice.
|
Plant Foods Hum Nutr
|
2011
|
0.78
|
|
32
|
Rosuvastatin reduces plasma lipids by inhibiting VLDL production and enhancing hepatobiliary lipid excretion in ApoE*3-leiden mice.
|
J Cardiovasc Pharmacol
|
2005
|
0.77
|
|
33
|
Hypoxia and Complement-and-Coagulation Pathways in the Deceased Organ Donor as the Major Target for Intervention to Improve Renal Allograft Outcome.
|
Transplantation
|
2015
|
0.77
|
|
34
|
Chronic prednisolone treatment aggravates hyperglycemia in mice fed a high-fat diet but does not worsen dietary fat-induced insulin resistance.
|
Endocrinology
|
2012
|
0.76
|
|
35
|
Neonatal dexamethasone administration causes progressive renal damage due to induction of an early inflammatory response.
|
Am J Physiol Renal Physiol
|
2008
|
0.75
|