1
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Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
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Nat Genet
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2011
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3.18
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2
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Seventy-five genetic loci influencing the human red blood cell.
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Nature
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2012
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2.77
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3
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Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography.
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J Clin Oncol
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2008
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2.03
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4
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Staging of carcinoid tumours with 18F-DOPA PET: a prospective, diagnostic accuracy study.
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Lancet Oncol
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2006
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1.79
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5
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Plasma free metanephrine measurement using automated online solid-phase extraction HPLC tandem mass spectrometry.
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Clin Chem
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2007
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1.74
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6
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Long-range neural and gap junction protein-mediated cues control polarity during planarian regeneration.
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Dev Biol
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2009
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1.62
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7
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Traditionally living populations in East Africa have a mean serum 25-hydroxyvitamin D concentration of 115 nmol/l.
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Br J Nutr
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2012
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1.57
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8
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Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake.
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Arterioscler Thromb Vasc Biol
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2007
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1.56
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9
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Platelet serotonin levels in pervasive developmental disorders and mental retardation: diagnostic group differences, within-group distribution, and behavioral correlates.
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J Am Acad Child Adolesc Psychiatry
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2004
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1.53
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10
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Carcinoid crisis after injection of 6-18F-fluorodihydroxyphenylalanine in a patient with metastatic carcinoid.
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J Nucl Med
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2005
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1.45
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11
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Accuracy of 6 routine 25-hydroxyvitamin D assays: influence of vitamin D binding protein concentration.
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Clin Chem
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2012
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1.44
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12
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Serotonin signaling is a very early step in patterning of the left-right axis in chick and frog embryos.
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Curr Biol
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2005
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1.40
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13
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Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.
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Gastroenterology
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2004
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1.36
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14
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Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
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Am J Hum Genet
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2012
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1.29
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15
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Vitamin D status indicators in indigenous populations in East Africa.
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Eur J Nutr
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2012
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1.27
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16
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111In-octreotide is superior to 123I-metaiodobenzylguanidine for scintigraphic detection of head and neck paragangliomas.
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J Nucl Med
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2008
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1.21
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17
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Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
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Proc Natl Acad Sci U S A
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2012
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1.14
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18
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6-[F-18]Fluoro-L-dihydroxyphenylalanine positron emission tomography is superior to conventional imaging with (123)I-metaiodobenzylguanidine scintigraphy, computer tomography, and magnetic resonance imaging in localizing tumors causing catecholamine excess.
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J Clin Endocrinol Metab
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2009
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1.11
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19
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Catechol-o-methyltransferase polymorphism and susceptibility to major depressive disorder modulates psychological stress response.
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Psychiatr Genet
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2007
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1.10
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20
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Apparent loss of urinary albumin during long-term frozen storage: HPLC vs immunonephelometry.
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Clin Chem
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2007
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1.08
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21
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Falsely low urinary albumin concentrations after prolonged frozen storage of urine samples.
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Clin Chem
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2005
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1.03
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22
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Dietary influences on plasma and urinary metanephrines: implications for diagnosis of catecholamine-producing tumors.
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J Clin Endocrinol Metab
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2009
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1.03
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23
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Short-term vitamin D3 supplementation lowers plasma renin activity in patients with stable chronic heart failure: an open-label, blinded end point, randomized prospective trial (VitD-CHF trial).
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Am Heart J
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2013
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1.01
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24
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Molecular imaging in neuroendocrine tumors: molecular uptake mechanisms and clinical results.
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Crit Rev Oncol Hematol
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2009
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1.00
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25
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Antiproteinuric treatment reduces urinary loss of vitamin D-binding protein but does not affect vitamin D status in patients with chronic kidney disease.
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J Steroid Biochem Mol Biol
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2011
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1.00
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26
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Differential effects of 5-HTTLPR and DRD2/ANKK1 polymorphisms on electrocortical measures of error and feedback processing in children.
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Clin Neurophysiol
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2008
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1.00
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27
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Bone metastases in carcinoid tumors: clinical features, imaging characteristics, and markers of bone metabolism.
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J Nucl Med
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2003
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1.00
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28
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Iodine-123 metaiodobenzylguanidine scintigraphy in localising phaeochromocytomas--experience and meta-analysis.
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Anticancer Res
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2006
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0.99
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29
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Tryptophan as a link between psychopathology and somatic states.
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Psychosom Med
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2003
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0.99
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30
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Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry.
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J Chromatogr B Analyt Technol Biomed Life Sci
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2009
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0.99
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31
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Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia.
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J Biol Chem
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2007
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0.98
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32
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Serotonin transporter intron 2 polymorphism associated with rigid-compulsive behaviors in Dutch individuals with pervasive developmental disorder.
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Am J Med Genet B Neuropsychiatr Genet
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2005
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0.96
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33
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Psychophysiological biomarkers explaining the association between depression and prognosis in coronary artery patients: a critical review of the literature.
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Neurosci Biobehav Rev
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2009
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0.95
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34
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Irritability rather than depression during interferon treatment is linked to increased tryptophan catabolism.
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Psychosom Med
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2005
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0.94
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35
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Protease activity of plasma hemopexin.
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Kidney Int
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2005
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0.92
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36
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An unusual cause of ventricular fibrillation.
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Lancet
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37
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The role of indoleamine 2,3-dioxygenase in a mouse model of neuroinflammation-induced depression.
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J Alzheimers Dis
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2012
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0.92
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38
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Patients with carcinoid syndrome exhibit symptoms of aggressive impulse dysregulation.
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Psychosom Med
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2004
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39
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The role of liquid chromatography-tandem mass spectrometry in the clinical laboratory.
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J Chromatogr B Analyt Technol Biomed Life Sci
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2011
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40
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Catecholamine-synthesizing enzymes in carcinoid tumors and pheochromocytomas.
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Clin Chem
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2003
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0.88
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41
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Complications of midgut carcinoid tumors and carcinoid syndrome.
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Neuroendocrinology
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2004
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0.87
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42
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18F-dihydroxyphenylalanine PET in patients with biochemical evidence of medullary thyroid cancer: relation to tumor differentiation.
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J Nucl Med
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2008
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0.86
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43
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Biochemical markers in the follow-up of medullary thyroid cancer.
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Thyroid
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2006
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44
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Vitamin k intake and plasma desphospho-uncarboxylated matrix Gla-protein levels in kidney transplant recipients.
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PLoS One
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2012
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45
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Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?
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J Clin Endocrinol Metab
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2010
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46
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Serum tryptophan and kynurenine concentrations as parameters for indoleamine 2,3-dioxygenase activity in patients with endometrial, ovarian, and vulvar cancer.
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Int J Gynecol Cancer
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2011
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0.85
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47
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Persistent low urinary excretion of 5-HIAA is a marker for favourable survival during follow-up in patients with disseminated midgut carcinoid tumours.
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Eur J Cancer
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48
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Associations of 25(OH) and 1,25(OH)2 vitamin D with long-term outcomes in stable renal transplant recipients.
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J Clin Endocrinol Metab
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0.83
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49
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Variation of the gene coding for DARPP-32 (PPP1R1B) and brain connectivity during associative emotional learning.
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Neuroimage
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2011
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0.83
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50
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Tryptophan as an evolutionarily conserved signal to brain serotonin: molecular evidence and psychiatric implications.
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World J Biol Psychiatry
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51
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Variants of the SLC6A3 (DAT1) polymorphism affect performance monitoring-related cortical evoked potentials that are associated with ADHD.
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Biol Psychol
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2010
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0.83
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52
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Which method for quantifying urinary albumin excretion gives what outcome? A comparison of immunonephelometry with HPLC.
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Kidney Int Suppl
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2004
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53
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The development of peripartum depressive symptoms is associated with gene polymorphisms of MAOA, 5-HTT and COMT.
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Prog Neuropsychopharmacol Biol Psychiatry
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2009
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54
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Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells.
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Cancer Res
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2008
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55
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Prolonged frozen storage of urine reduces the value of albuminuria for mortality prediction.
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Clin Chem
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2007
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56
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Thyroid hormone status and health-related quality of life in the LifeLines Cohort Study.
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Thyroid
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Gene therapy with adenovirus-delivered indoleamine 2,3-dioxygenase improves renal function and morphology following allogeneic kidney transplantation in rat.
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J Gene Med
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Reactivity of serotonin in whole blood.
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Biol Psychiatry
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Measuring serotonin synthesis: from conventional methods to PET tracers and their (pre)clinical implications.
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Eur J Nucl Med Mol Imaging
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Prognostic role of indoleamine 2,3-dioxygenase in endometrial carcinoma.
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Gynecol Oncol
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Clinical utility of an automated immunochemiluminometric thyroglobulin assay in differentiated thyroid carcinoma.
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Clin Chem
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63
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Low plasma tryptophan in carcinoid patients is associated with increased urinary cortisol excretion.
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Psychoneuroendocrinology
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Investigating the molecular basis of major depressive disorder etiology: a functional convergent genetic approach.
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Ann N Y Acad Sci
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Brief report: normal intestinal permeability at elevated platelet serotonin levels in a subgroup of children with pervasive developmental disorders in Curaçao (The Netherlands antilles).
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J Autism Dev Disord
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66
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Vasopressin release is enhanced by the Hemocontrol biofeedback system and could contribute to better haemodynamic stability during haemodialysis.
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Biochemical and behavioral effects of long-term citalopram administration and discontinuation in rats: role of serotonin synthesis.
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Neurochem Int
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Urinary excretion of 5-hydroxyindoleacetic acid, serotonin and 6-sulphatoxymelatonin in normoserotonemic and hyperserotonemic autistic individuals.
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Neuropsychobiology
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Discovery and consequences of apolipoprotein-epsilon(3Groningen): a G-insertion in codon 95/96 that is predicted to cause a premature stop codon.
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Ann Clin Biochem
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70
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Sexual function in patients with metastatic midgut carcinoid tumours.
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71
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Assessment of intestinal permeability in (premature) neonates by sugar absorption tests.
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Methods Mol Biol
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72
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Procalcitonin levels predict clinical course and progression-free survival in patients with medullary thyroid cancer.
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Cancer
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2010
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73
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combination of vascular endothelial growth factor (VEGF) and thymidine phosphorylase (TP) to improve angiogenic gene therapy.
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Angiogenesis
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Unilateral and bilateral adrenalectomy for pheochromocytoma requires adjustment of urinary and plasma metanephrine reference ranges.
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Serotonin rising.
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N Engl J Med
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Urinary 5-HIAA measurement using automated on-line solid-phase extraction-high-performance liquid chromatography-tandem mass spectrometry.
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J Chromatogr B Analyt Technol Biomed Life Sci
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2008
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77
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Total 18F-dopa PET tumour uptake reflects metabolic endocrine tumour activity in patients with a carcinoid tumour.
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Fasting vs nonfasting plasma homocysteine concentrations for diagnosis of hyperhomocysteinemia.
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Effects of potassium supplementation on markers of osmoregulation and volume regulation: results of a fully controlled dietary intervention study.
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Niacin (Vitamin B3) Supplementation in Patients with Serotonin-Producing Neuroendocrine Tumor.
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Intravenous tissue plasminogen activator in patients with stroke increases the bioavailability of insulin-like growth factor-1.
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Stroke
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Dopamine excess in patients with head and neck paragangliomas.
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Measurement of plasma vitamin K1 (phylloquinone) and K2 (menaquinones-4 and -7) using HPLC-tandem mass spectrometry.
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Clin Chem Lab Med
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Elevated urinary free and deconjugated catecholamines after consumption of a catecholamine-rich diet.
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Automated mass spectrometric analysis of urinary and plasma serotonin.
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Anal Bioanal Chem
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Empathic accuracy and oxytocin after tryptophan depletion in adults at risk for depression.
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Psychopharmacology (Berl)
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Quick identification of acute chest pain patients study (QICS).
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BMC Cardiovasc Disord
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Association between methylation of the SLC6A4 promoter region in peripheral blood leukocytes and methylation in amygdala tissue.
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Psychosom Med
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Plasma chromogranin A levels are increased in a small portion of patients with hereditary head and neck paragangliomas.
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Clin Endocrinol (Oxf)
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Assay-specific pitfalls of catecholamine HPLC assays.
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Clin Chem Lab Med
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An observational study on disturbed peripheral circadian rhythms in hemodialysis patients.
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Abdominal angina in patients with a midgut carcinoid, a sign of severe pathology.
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Biochemical markers predictive for bone marrow involvement in systemic mastocytosis.
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Haematologica
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Effect of interferon and 5-fluorouracil on serum VEGF levels in neuroendocrine tumours.
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Acta Oncol
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Catecholamine-Synthesizing Enzymes Are Expressed in Parasympathetic Head and Neck Paraganglioma Tissue.
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Neuroendocrinology
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Dopamine concentration in blood platelets is elevated in patients with head and neck paragangliomas.
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Clin Chem Lab Med
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Current status and future developments of LC-MS/MS in clinical chemistry for quantification of biogenic amines.
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Clin Biochem
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Automated on-line solid-phase extraction coupled with HPLC for measurement of 5-hydroxyindole-3-acetic acid in urine.
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Clin Chem
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A multicenter comparison of whole blood vitamin B6 assays.
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Clin Chem Lab Med
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