A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate.

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Published in J Matern Fetal Neonatal Med on January 01, 2008

Authors

Roberto Romero1, Jyh Kae Nien, Jimmy Espinoza, David Todem, Wenjiang Fu, Hwan Chung, Juan Pedro Kusanovic, Francesca Gotsch, Offer Erez, Shali Mazaki-Tovi, Ricardo Gomez, Sam Edwin, Tinnakorn Chaiworapongsa, Richard J Levine, S Ananth Karumanchi

Author Affiliations

1: Perinatology Research Branch, National Institute of Child Health and Human Development, NIH/DHHS, Bethesda, MD 20892, USA. prbchiefstaff@med.wayne.edu

Associated clinical trials:

Usefulness of Extracorporeal Removal of sFLT-1 in Women With Very Early Severe Preeclampsia (ADENA) | NCT02286284

MorbiMortality Amelioration in Preeclamptic Primiparas Study. MoMA Pre Prim Study (MOMA) | NCT00763672

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A sonographic short cervix as the only clinical manifestation of intra-amniotic infection. J Perinat Med (2006) 1.82

Recombinant vascular endothelial growth factor 121 infusion lowers blood pressure and improves renal function in rats with placentalischemia-induced hypertension. Hypertension (2009) 1.82

Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia. Young Investigator Award. Am J Obstet Gynecol (2004) 1.81

Diagnostic utility of soluble fms-like tyrosine kinase 1 and soluble endoglin in hypertensive diseases of pregnancy. Am J Obstet Gynecol (2007) 1.80

The neuropathology of fatal cerebral malaria in malawian children. Am J Pathol (2011) 1.79

Misclassification of maternal smoking status and its effects on an epidemiologic study of pregnancy outcomes. Nicotine Tob Res (2007) 1.78

Soluble Fms-like tyrosine kinase 1 and endothelial dysfunction in the pathogenesis of preeclampsia. Pediatr Res (2005) 1.78

Infection and prematurity and the role of preventive strategies. Semin Neonatol (2002) 1.78

Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery. J Matern Fetal Neonatal Med (2010) 1.77

Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. Am J Obstet Gynecol (2010) 1.75

Prevalence and diversity of microbes in the amniotic fluid, the fetal inflammatory response, and pregnancy outcome in women with preterm pre-labor rupture of membranes. Am J Reprod Immunol (2010) 1.74