Barry S Coller

Author PubWeight™ 55.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature 2004 5.87
2 Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proc Natl Acad Sci U S A 2002 2.72
3 Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease. Blood 2005 2.37
4 In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1. Blood 2008 1.94
5 Assessing research participants' perceptions of their clinical research experiences. Clin Transl Sci 2011 1.88
6 Adjuvant treatment with a glycoprotein IIb/IIIa receptor inhibitor increases the therapeutic window for low-dose tissue plasminogen activator administration in a rat model of embolic stroke. Circulation 2003 1.77
7 The Rockefeller University Navigation Program: a structured multidisciplinary protocol development and educational program to advance translational research. Clin Transl Sci 2014 1.37
8 Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation. Proc Natl Acad Sci U S A 2004 1.36
9 Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening. Blood 2010 1.29
10 Assessing participant-centered outcomes to improve clinical research. N Engl J Med 2013 1.26
11 Platelet TGF-β1 contributions to plasma TGF-β1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload. Blood 2011 1.20
12 Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes. Blood 2003 1.17
13 Development of a research participants' perception survey to improve clinical research. Clin Transl Sci 2012 1.16
14 Ligand density dramatically affects integrin alpha IIb beta 3-mediated platelet signaling and spreading. Blood 2007 1.15
15 Application of high-throughput screening to identify a novel alphaIIb-specific small- molecule inhibitor of alphaIIbbeta3-mediated platelet interaction with fibrinogen. Blood 2007 1.11
16 Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS. Sci Transl Med 2012 1.07
17 Reflections on being a Chair of Medicine, 1993 to 2001 - Part 2. Am J Med 2004 1.06
18 Reflections on being a chair of medicine, 1993 to 2001--part 1. Am J Med 2004 1.06
19 Antibody blockade or mutation of the fibrinogen gamma-chain C-terminus is more effective in inhibiting murine arterial thrombus formation than complete absence of fibrinogen. Blood 2003 0.99
20 Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis. Blood 2002 0.97
21 Three-dimensional reconstruction of intact human integrin αIIbβ3: new implications for activation-dependent ligand binding. Blood 2013 0.96
22 Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel alphaIIb-specific alphaIIbbeta3 antagonist. Blood 2009 0.96
23 Creating an ontology-based human phenotyping system: The Rockefeller University bleeding history experience. Clin Transl Sci 2009 0.95
24 Fibrin but not adsorbed fibrinogen supports fibronectin assembly by spread platelets. Effects of the interaction of alphaIIb beta3 with the C terminus of the fibrinogen gamma-chain. J Biol Chem 2005 0.93
25 In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1. PLoS One 2009 0.93
26 Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3. J Biol Chem 2010 0.93
27 Disulfide bond disruption by a beta 3-Cys549Arg mutation in six Jordanian families with Glanzmann thrombasthenia causes diminished production of constitutively active alpha IIb beta 3. Thromb Haemost 2007 0.92
28 Mapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation. Blood 2007 0.92
29 A data-rich recruitment core to support translational clinical research. Clin Transl Sci 2014 0.91
30 Functional and computational studies of the ligand-associated metal binding site of beta3 integrins. Proteins 2008 0.90
31 Morphological and functional platelet abnormalities in Berkeley sickle cell mice. Blood Cells Mol Dis 2008 0.90
32 Targeted molecular dynamics reveals overall common conformational changes upon hybrid domain swing-out in beta3 integrins. Proteins 2009 0.88
33 Dynamics of GPIIb/IIIa-mediated platelet-platelet interactions in platelet adhesion/thrombus formation on collagen in vitro as revealed by videomicroscopy. Blood 2003 0.87
34 Monocyte-derived tissue factor contributes to stent thrombosis in an in vitro system. J Am Coll Cardiol 2004 0.85
35 alphaIIbbeta3 biogenesis is controlled by engagement of alphaIIb in the calnexin cycle via the N15-linked glycan. Blood 2005 0.84
36 Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor β1 (TGF-β1) activation. J Biol Chem 2013 0.84
37 Effects of abciximab on the acute pathology of blood vessels after arterial stenting in nonhuman primates. J Am Coll Cardiol 2002 0.83
38 Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group. Circulation 2012 0.83
39 Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3. J Biol Chem 2004 0.81
40 Molecular diversity of Glanzmann thrombasthenia in southern India: new insights into mRNA splicing and structure-function correlations of alphaIIbbeta3 integrin (ITGA2B, ITGB3). Hum Mutat 2006 0.81
41 Professing and living the oath: teaching medicine as a profession. Am J Med 2002 0.79
42 Structure-based virtual screening of small-molecule antagonists of platelet integrin αIIbβ3 that do not prime the receptor to bind ligand. J Comput Aided Mol Des 2012 0.79
43 Research participant-centered outcomes at NIH-supported clinical research centers. Clin Transl Sci 2014 0.78
44 Two new beta3 integrin mutations in Indian patients with Glanzmann thrombasthenia: localization of mutations affecting cysteine residues in integrin beta3. Thromb Haemost 2002 0.78
45 Helping Basic Scientists Engage With Community Partners to Enrich and Accelerate Translational Research. Acad Med 2016 0.75
46 Phenotyping bleeding. Curr Opin Hematol 2012 0.75
47 From the Bench to the Barbershop: Community Engagement to Raise Awareness About Community-Acquired Methicillin-Resistant <i>Staphylococcus aureus</i> and Hepatitis C Virus Infection. Prog Community Health Partnersh 2016 0.75
48 Evidence for megakaryocyte engraftment following reduced-intensity conditioning. Exp Hematol 2004 0.75