Published in J Immunol on January 15, 2008
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet (2009) 4.97
Autoantibody profiling to identify biomarkers of key pathogenic pathways in mucinous ovarian cancer. Eur J Cancer (2010) 0.96
Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass. PLoS One (2010) 0.90
Pancreas β cell regeneration and type 1 diabetes (Review). Exp Ther Med (2014) 0.81
Cyclin D3 promotes pancreatic β-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes. Proc Natl Acad Sci U S A (2014) 0.78
Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet (2002) 9.48
Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet (2009) 8.54
Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial. JAMA (2003) 8.47
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature (2009) 7.96
The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature (2009) 7.39
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell (2009) 4.59
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell (2004) 4.39
Improvement of glycemic control in subjects with poorly controlled type 2 diabetes: comparison of two treatment algorithms using insulin glargine. Diabetes Care (2005) 3.55
Heart failure events with rosiglitazone in type 2 diabetes: data from the RECORD clinical trial. Eur Heart J (2010) 2.68
H-NS-mediated repression of CRISPR-based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO. Mol Microbiol (2010) 2.55
Reprogramming in vivo produces teratomas and iPS cells with totipotency features. Nature (2013) 2.47
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell (2013) 2.43
Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1). Cancer Cell (2005) 1.78
Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes. Diabetes Care (2004) 1.75
Cyclins and CDKS in development and cancer: lessons from genetically modified mice. Front Biosci (2006) 1.69
Identification of a pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in the pancreas. Biochem J (2009) 1.64
Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number. Oncogene (2003) 1.62
GLP-1 and changes in glucose tolerance following gastric bypass surgery in morbidly obese subjects. Obes Surg (2006) 1.60
Histone demethylase LSD1 regulates adipogenesis. J Biol Chem (2010) 1.50
[Organization and functioning model of biomedical research structures. Situation and future challenges]. Med Clin (Barc) (2008) 1.46
Cohesin component dynamics during meiotic prophase I in mammalian oocytes. Chromosome Res (2004) 1.43
CDK2 is required for proper homologous pairing, recombination and sex-body formation during male mouse meiosis. J Cell Sci (2009) 1.33
Histone H3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes. J Biol Chem (2006) 1.21
In vivo imaging of lymphatic vessels in development, wound healing, inflammation, and tumor metastasis. Proc Natl Acad Sci U S A (2012) 1.19
Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer. Cancer Res (2003) 1.16
Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development. Development (2011) 1.15
A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice. Diabetes (2002) 1.10
Induction of pancreatic islet cell differentiation by the neurogenin-neuroD cascade. Differentiation (2007) 1.09
TRF1 is a stem cell marker and is essential for the generation of induced pluripotent stem cells. Nat Commun (2013) 1.07
Short-term effects of gastric bypass surgery on circulating ghrelin levels. Obes Res (2004) 1.06
BglJ-RcsB heterodimers relieve repression of the Escherichia coli bgl operon by H-NS. J Bacteriol (2010) 1.06
Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance. J Endocrinol (2014) 1.05
Detection of low-avidity CD4+ T cells using recombinant artificial APC: following the antiovalbumin immune response. J Immunol (2003) 1.04
Circulating peptide YY, weight loss, and glucose homeostasis after gastric bypass surgery in morbidly obese subjects. Ann Surg (2008) 1.04
Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome. Proc Natl Acad Sci U S A (2011) 1.02
Chromatin and chromatin-modifying proteins in adipogenesis. Biochem Cell Biol (2007) 1.02
Mice thrive without Cdk4 and Cdk2. Mol Oncol (2007) 1.02
Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One (2008) 1.00
Effect of the addition of rosiglitazone to metformin or sulfonylureas versus metformin/sulfonylurea combination therapy on ambulatory blood pressure in people with type 2 diabetes: a randomized controlled trial (the RECORD study). Cardiovasc Diabetol (2008) 0.99
Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth. Blood (2012) 0.99
Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity. Mol Metab (2012) 0.98
Insulin hypersecretion in islets from diet-induced hyperinsulinemic obese female mice is associated with several functional adaptations in individual β-cells. Endocrinology (2013) 0.97
Insulin resistance, inflammation, and the metabolic syndrome following Roux-en-Y gastric bypass surgery in severely obese subjects. Diabetes Care (2007) 0.97
A Cre-reporter transgenic mouse expressing the far-red fluorescent protein Katushka. Genesis (2011) 0.97
Involvement of the clock gene Rev-erb alpha in the regulation of glucagon secretion in pancreatic alpha-cells. PLoS One (2013) 0.97
CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation. Circulation (2014) 0.96
Development and functional characterization of insulin-releasing human pancreatic beta cell lines produced by electrofusion. J Biol Chem (2011) 0.93
Driving the cell cycle to cancer. Adv Exp Med Biol (2003) 0.93
Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action. PLoS One (2007) 0.92
A chromatin perspective of adipogenesis. Organogenesis (2010) 0.92
The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse. PLoS Genet (2013) 0.91
Terminal deoxynucleotidyltransferase deficiency decreases autoimmune disease in diabetes-prone nonobese diabetic mice and lupus-prone MRL-Fas(lpr) mice. J Immunol (2004) 0.91
Cognitive abilities, androgen levels, and body mass index in 5-year-old children. Horm Behav (2005) 0.91
Different telomere-length dynamics at the inner cell mass versus established embryonic stem (ES) cells. Proc Natl Acad Sci U S A (2011) 0.90
Insulin glargine-based therapy improves glycemic control in patients with type 2 diabetes sub-optimally controlled on premixed insulin therapies. Diabetes Res Clin Pract (2007) 0.90
Anti-peripherin B lymphocytes are positively selected during diabetogenesis. Mol Immunol (2008) 0.89
FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature. J Clin Invest (2015) 0.89
Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells. PLoS One (2011) 0.88
Pulsatile insulin release from islets isolated from three subjects with type 2 diabetes. Diabetes (2002) 0.88
Diabetes as a case study of chronic disease management with a personalized approach: the role of a structured feedback loop. Diabetes Res Clin Pract (2012) 0.88
Lymph node transplantation results in spontaneous lymphatic reconnection and restoration of lymphatic flow. Plast Reconstr Surg (2014) 0.88
Integration of DIGE and bioinformatics analyses reveals a role of the antiobesity agent tungstate in redox and energy homeostasis pathways in brown adipose tissue. Mol Cell Proteomics (2007) 0.87
Effects of prenatal and early life malnutrition: evidence from the Greek famine. J Health Econ (2011) 0.86
Melatonin prevents mitochondrial dysfunction and insulin resistance in rat skeletal muscle. J Pineal Res (2014) 0.85
In vivo diabetogenic action of CD4+ T lymphocytes requires Fas expression and is independent of IL-1 and IL-18. Eur J Immunol (2011) 0.85
Prevalence of the metabolic syndrome in Spain using regional cutoff points for waist circumference: the di@bet.es study. Acta Diabetol (2013) 0.85
Increased Susceptibility to Skin Carcinogenesis in TREX2 Knockout Mice. Cancer Res (2009) 0.85
Comparison of quick diagnosis units and conventional hospitalization for the diagnosis of cancer in Spain: a descriptive cohort study. Oncology (2012) 0.85
Human DQ8 can substitute for murine I-Ag7 in the selection of diabetogenic T cells restricted to I-Ag7. J Immunol (2002) 0.85
Tungstate decreases weight gain and adiposity in obese rats through increased thermogenesis and lipid oxidation. Endocrinology (2005) 0.84
Characterization of the transcriptional activity of the basic helix-loop-helix (bHLH) transcription factor Atoh8. Biochim Biophys Acta (2013) 0.84
Islet amyloid polypeptide gene promoter polymorphisms are not associated with Type 2 diabetes or with the severity of islet amyloidosis. Biochim Biophys Acta (2005) 0.84
Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2. Can J Physiol Pharmacol (2014) 0.84
The antidiabetic agent sodium tungstate activates glycogen synthesis through an insulin receptor-independent pathway. J Biol Chem (2003) 0.84
Insulin lispro is as effective as regular insulin in optimising metabolic control and preserving beta-cell function at onset of type 1 diabetes mellitus. Diabetes Res Clin Pract (2003) 0.84
Development of autoreactive diabetogenic T cells in the thymus of NOD mice. J Autoimmun (2004) 0.83
Incidence and prevalence of unrecognized myocardial infarction in people with diabetes: a substudy of the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study. Diabetes Care (2011) 0.83
BACE2 plays a role in the insulin receptor trafficking in pancreatic ß-cells. Am J Physiol Endocrinol Metab (2010) 0.83
In vivo JNK activation in pancreatic β-cells leads to glucose intolerance caused by insulin resistance in pancreas. Diabetes (2013) 0.83
Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach. BMC Genomics (2009) 0.83
Intra-abdominal fat adiponectin receptors expression and cardiovascular metabolic risk factors in obesity and diabetes. Obes Surg (2006) 0.83
The efficiency of telemedicine to optimize metabolic control in patients with type 1 diabetes mellitus: Telemed study. Diabetes Technol Ther (2014) 0.82
Expression of TMEM16A and SLC4A4 in human pancreatic islets. Cell Physiol Biochem (2012) 0.82
Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL-18-binding protein: Fc construct. Eur J Immunol (2003) 0.81
In vivo detection of peripherin-specific autoreactive B cells during type 1 diabetes pathogenesis. J Immunol (2014) 0.81
Aggression, dominance, and affiliation: Their relationships with androgen levels and intelligence in 5-year-old children. Horm Behav (2006) 0.80
Ambient temperature and prevalence of obesity in the Spanish population: The Di@bet.es study. Obesity (Silver Spring) (2014) 0.80
Application of electrophoretic mobility shift assay and chromatin immunoprecipitation in the study of transcription in adipose cells. Methods Mol Biol (2008) 0.80
New aminoacyl-tRNA synthetase-like protein in insecta with an essential mitochondrial function. J Biol Chem (2010) 0.80
Sequence and epigenetic determinants in the regulation of the Math6 gene by Neurogenin3. Differentiation (2011) 0.80
Phosphorylation events implicating p38 and PI3K mediate tungstate-effects in MIN6 beta cells. Biochem Biophys Res Commun (2007) 0.80
A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse. Int Immunol (2003) 0.80
RcsB-BglJ-mediated activation of Cascade operon does not induce the maturation of CRISPR RNAs in E. coli K12. RNA Biol (2013) 0.80
Role of IGFBP-3 in the regulation of β-cell mass during obesity: adipose tissue/β-cell cross talk. Endocrinology (2011) 0.80
The effect of abortion legalization on sexual behavior: evidence from sexually transmitted diseases. J Legal Stud (2003) 0.79