Published in Diabetes on January 09, 2008
Cell-cell and intracellular lactate shuttles. J Physiol (2009) 2.48
Neuronal regulation of homeostasis by nutrient sensing. Nat Med (2010) 1.61
Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia. Endocrinology (2010) 1.53
Hypothalamic glucagon signaling inhibits hepatic glucose production. Nat Med (2013) 1.11
Hypothalamic protein kinase C regulates glucose production. Diabetes (2008) 1.07
Multifunctional role of astrocytes as gatekeepers of neuronal energy supply. Front Cell Neurosci (2013) 1.00
Activation of N-methyl-D-aspartate (NMDA) receptors in the dorsal vagal complex lowers glucose production. J Biol Chem (2010) 0.99
Nutrient-sensing mechanisms in the gut as therapeutic targets for diabetes. Diabetes (2013) 0.97
Hypothalamic nutrient sensing activates a forebrain-hindbrain neuronal circuit to regulate glucose production in vivo. Diabetes (2010) 0.94
Glucose transporter-1 in the hypothalamic glial cells mediates glucose sensing to regulate glucose production in vivo. Diabetes (2011) 0.93
Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation. J Lipid Res (2008) 0.90
Hypothalamic sensing of circulating lactate regulates glucose production. J Cell Mol Med (2010) 0.84
Effect of sulfonylureas administered centrally on the blood glucose level in immobilization stress model. Korean J Physiol Pharmacol (2015) 0.76
Inhibition of glycine transporter-1 in the dorsal vagal complex improves metabolic homeostasis in diabetes and obesity. Nat Commun (2016) 0.75
Hypothalamic K(ATP) channels control hepatic glucose production. Nature (2005) 4.56
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. J Biol Chem (2004) 3.31
Upper intestinal lipids trigger a gut-brain-liver axis to regulate glucose production. Nature (2008) 3.31
Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes. Nat Med (2012) 2.48
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. J Clin Invest (2006) 1.94
Molecular disruption of hypothalamic nutrient sensing induces obesity. Nat Neurosci (2006) 1.87
Intestinal cholecystokinin controls glucose production through a neuronal network. Cell Metab (2009) 1.37
N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress. Am J Physiol Endocrinol Metab (2003) 1.25
Lipid-induced beta-cell dysfunction in vivo in models of progressive beta-cell failure. Am J Physiol Endocrinol Metab (2006) 1.21
A balance of lipid-sensing mechanisms in the brain and liver. Cell Metab (2007) 1.11
Hypothalamic glucagon signaling inhibits hepatic glucose production. Nat Med (2013) 1.11
Hypothalamic resistin induces hepatic insulin resistance. J Clin Invest (2007) 1.10
Hypothalamic protein kinase C regulates glucose production. Diabetes (2008) 1.07
CNS regulation of glucose homeostasis. Physiology (Bethesda) (2009) 1.06
Hypothalamic AMP-activated protein kinase regulates glucose production. Diabetes (2010) 1.02
Activation of N-methyl-D-aspartate (NMDA) receptors in the dorsal vagal complex lowers glucose production. J Biol Chem (2010) 0.99
Hypothalamic leucine metabolism regulates liver glucose production. Diabetes (2012) 0.99
Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats. Diabetes (2011) 0.98
Nutrient-sensing mechanisms in the gut as therapeutic targets for diabetes. Diabetes (2013) 0.97
Hypothalamic nutrient sensing activates a forebrain-hindbrain neuronal circuit to regulate glucose production in vivo. Diabetes (2010) 0.94
Insulin activates Erk1/2 signaling in the dorsal vagal complex to inhibit glucose production. Cell Metab (2012) 0.94
Hormonal signaling in the gut. J Biol Chem (2014) 0.93
Lipid sensing and insulin resistance in the brain. Cell Metab (2012) 0.93
Duodenal mucosal protein kinase C-δ regulates glucose production in rats. Gastroenterology (2011) 0.93
Glucose transporter-1 in the hypothalamic glial cells mediates glucose sensing to regulate glucose production in vivo. Diabetes (2011) 0.93
Long-term inflammation and glucocorticoid therapy impair skeletal modeling during growth in childhood Crohn disease. J Clin Endocrinol Metab (2013) 0.92
Central lactate metabolism regulates food intake. Am J Physiol Endocrinol Metab (2008) 0.91
Glycine normalizes hepatic triglyceride-rich VLDL secretion by triggering the CNS in high-fat fed rats. Circ Res (2012) 0.88
Insulin resistance following continuous, chronic olanzapine treatment: an animal model. Schizophr Res (2008) 0.87
Duodenal PKC-δ and cholecystokinin signaling axis regulates glucose production. Diabetes (2011) 0.85
Lipid sensing in the gut, brain and liver. Trends Endocrinol Metab (2011) 0.85
Effects of portal free fatty acid elevation on insulin clearance and hepatic glucose flux. Am J Physiol Endocrinol Metab (2006) 0.85
Upper intestinal lipids regulate energy and glucose homeostasis. Cell Mol Life Sci (2009) 0.84
Duodenal activation of cAMP-dependent protein kinase induces vagal afferent firing and lowers glucose production in rats. Gastroenterology (2012) 0.84
Hypothalamic sensing of circulating lactate regulates glucose production. J Cell Mol Med (2010) 0.84
Insulin and glucagon signaling in the central nervous system. Rev Endocr Metab Disord (2013) 0.82
Insulin inhibits glucose production by a direct effect in diabetic depancreatized dogs during euglycemia. Am J Physiol Endocrinol Metab (2002) 0.82
Gut-brain signalling: how lipids can trigger the gut. Diabetes Metab Res Rev (2011) 0.81
Evidence for a role of proline and hypothalamic astrocytes in the regulation of glucose metabolism in rats. Diabetes (2012) 0.81
Modulation of hepatocellular swelling-activated K+ currents by phosphoinositide pathway-dependent protein kinase C. Am J Physiol Cell Physiol (2006) 0.80
Oleate-induced decrease in hepatocyte insulin binding is mediated by PKC-delta. Biochem Biophys Res Commun (2006) 0.79
Linking inflammation to the brain-liver axis. Diabetes (2012) 0.79
Is insulin action in the brain clinically relevant? Diabetes (2012) 0.78
Insulin signals through the dorsal vagal complex to regulate energy balance. Diabetes (2013) 0.78
Leptin and aging. Aging (Albany NY) (2014) 0.77
Immunologic impact of the intestine in metabolic disease. J Clin Invest (2017) 0.75
Corrigendum: Metformin activates a duodenal Ampk-dependent pathway to lower hepatic glucose production in rats. Nat Med (2016) 0.75
Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700. Diabetes (2017) 0.75
China needs to boost funding for graduate students to stay competitive. Nat Med (2011) 0.75
Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700. Diabetes (2017) 0.75
FK-614, a selective peroxisome proliferator-activated receptor gamma agonist, improves peripheral glucose utilization while decreasing hepatic insulin extraction in alloxan-induced diabetic dogs. Metabolism (2005) 0.75
Glucagon and lipid signaling in the hypothalamus. Mamm Genome (2014) 0.75