Published in Genetics on January 01, 2008
SUMO modification of DNA topoisomerase II: trying to get a CENse of it all. DNA Repair (Amst) (2009) 0.89
Restoration of topoisomerase 2 function by complementation of defective monomers in Drosophila. Genetics (2012) 0.78
The Identification of a Novel Mutant Allele of topoisomerase II in Caenorhabditis elegans Reveals a Unique Role in Chromosome Segregation During Spermatogenesis. Genetics (2016) 0.76
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
Genetic instabilities in human cancers. Nature (1998) 22.76
Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics (2001) 10.29
Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol (2000) 9.01
Identification and characterization of a nuclear pore complex protein. Cell (1986) 7.93
Genome-wide RNAi screening in Caenorhabditis elegans. Methods (2003) 7.83
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science (2006) 6.71
The vertebrate cell kinetochore and its roles during mitosis. Trends Cell Biol (1998) 5.87
Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev (1998) 5.78
Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol Cell (2000) 5.49
Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells. J Cell Biol (2001) 5.09
Conserved organization of centromeric chromatin in flies and humans. Dev Cell (2002) 5.06
Functional analysis of kinetochore assembly in Caenorhabditis elegans. J Cell Biol (2001) 4.82
Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication. Genes Dev (1999) 4.73
Chromosomal cohesin forms a ring. Cell (2003) 4.38
Establishing biorientation occurs with precocious separation of the sister kinetochores, but not the arms, in the early spindle of budding yeast. Cell (2000) 4.35
Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. Cell (1999) 4.17
Wapl controls the dynamic association of cohesin with chromatin. Cell (2006) 3.83
PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell (2007) 3.80
Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis. Annu Rev Genet (2001) 3.79
Transient sister chromatid separation and elastic deformation of chromosomes during mitosis in budding yeast. Cell (2000) 3.70
Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation. Nat Cell Biol (2000) 3.70
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell (2002) 3.65
Kinetochore structure, duplication, and distribution in mammalian cells: analysis by human autoantibodies from scleroderma patients. J Cell Biol (1981) 3.63
Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice. Proc Natl Acad Sci U S A (2000) 3.53
Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell (2004) 3.51
Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol (2005) 3.33
Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Curr Biol (2006) 3.14
A histone-H3-like protein in C. elegans. Nature (1999) 3.14
The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol Cell (2002) 2.85
Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis. Genes Dev (2002) 2.77
The kinetochores of Caenorhabditis elegans. Chromosoma (1982) 2.56
Chromosomal addresses of the cohesin component Mcd1p. J Cell Biol (2000) 2.56
A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction. Genes Dev (2001) 2.56
Crossing over during Caenorhabditis elegans meiosis requires a conserved MutS-based pathway that is partially dispensable in budding yeast. Genetics (1999) 2.54
Inducible overexpression, purification, and active site mapping of DNA topoisomerase II from the yeast Saccharomyces cerevisiae. J Biol Chem (1989) 2.33
Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II. Biochemistry (1989) 2.26
The structure and early evolution of recently arisen gene duplicates in the Caenorhabditis elegans genome. Genetics (2003) 1.94
Chromosome cohesion is regulated by a clock gene paralogue TIM-1. Nature (2003) 1.90
HCP-4, a CENP-C-like protein in Caenorhabditis elegans, is required for resolution of sister centromeres. J Cell Biol (2001) 1.81
DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism. Proc Natl Acad Sci U S A (1996) 1.77
Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model. Neurobiol Aging (2003) 1.72
Determination of cleavage planes. Cell (1993) 1.71
Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol (2006) 1.70
Topoisomerase II alpha is associated with the mammalian centromere in a cell cycle- and species-specific manner and is required for proper centromere/kinetochore structure. J Cell Biol (1996) 1.68
HCP-1, a protein involved in chromosome segregation, is localized to the centromere of mitotic chromosomes in Caenorhabditis elegans. J Cell Biol (1999) 1.59
Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes. Proc Natl Acad Sci U S A (1989) 1.58
Characterization of HCP-6, a C. elegans protein required to prevent chromosome twisting and merotelic attachment. Genes Dev (2002) 1.39
Proteolysis patterns of epitopically labeled yeast DNA topoisomerase II suggest an allosteric transition in the enzyme induced by ATP binding. Proc Natl Acad Sci U S A (1991) 1.36
Functional compatibility between isoform alpha and beta of type II DNA topoisomerase. J Cell Sci (2004) 1.31
A potential role for human cohesin in mitotic spindle aster assembly. J Biol Chem (2001) 1.22
Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology. J Mol Biol (2004) 1.18
On the simultaneous binding of eukaryotic DNA topoisomerase II to a pair of double-stranded DNA helices. J Biol Chem (1993) 1.12
Structure and dynamic organization of centromeres/prekinetochores in the nucleus of mammalian cells. J Cell Sci (1996) 1.11
The path of the DNA along the dimer interface of topoisomerase II. J Biol Chem (2004) 1.02
Analysis of functional domain organization in DNA topoisomerase II from humans and Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.00
HCP-4/CENP-C promotes the prophase timing of centromere resolution by enabling the centromere association of HCP-6 in Caenorhabditis elegans. Mol Cell Biol (2005) 0.97
Distinct developmental function of two Caenorhabditis elegans homologs of the cohesin subunit Scc1/Rad21. Mol Biol Cell (2003) 0.96
Human DNA topoisomerase IIbeta binds and cleaves four-way junction DNA in vitro. Nucleic Acids Res (1999) 0.89
Sister chromatid cohesion in silent chromatin: each sister to her own ring. Genes Dev (2006) 0.84
Chromosome segregation: correcting improperly attached chromosomes. Curr Biol (2006) 0.76
Spermatogenesis-specific features of the meiotic program in Caenorhabditis elegans. PLoS Genet (2009) 1.35
Changes in the N-glycome, glycoproteins with Asn-linked glycans, of Giardia lamblia with differentiation from trophozoites to cysts. Eukaryot Cell (2008) 0.99
A negative regulatory element controls mRNA abundance of the Leishmania mexicana Paraflagellar rod gene PFR2. Eukaryot Cell (2003) 0.92
Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans. Cell Div (2008) 0.87