Published in Proteomics on February 01, 2008
The SWISS-MODEL Repository and associated resources. Nucleic Acids Res (2008) 11.61
Overcoming the challenges of membrane protein crystallography. Curr Opin Struct Biol (2008) 1.57
EasyModeller: A graphical interface to MODELLER. BMC Res Notes (2010) 1.25
Enabling IMAC purification of low abundance recombinant proteins from E. coli lysates. Nat Methods (2009) 1.23
To automate or not to automate: this is the question. J Struct Funct Genomics (2010) 0.93
Approaches to automated protein crystal harvesting. Acta Crystallogr F Struct Biol Commun (2014) 0.93
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nat Methods (2015) 0.89
From laptop to benchtop to bedside: structure-based drug design on protein targets. Curr Pharm Des (2012) 0.85
Getting a grip on complexes. Curr Genomics (2009) 0.84
Facilitating protein crystal cryoprotection in thick-walled plastic capillaries by high-pressure cryocooling. J Appl Crystallogr (2009) 0.84
The Stanford Automated Mounter: pushing the limits of sample exchange at the SSRL macromolecular crystallography beamlines. J Appl Crystallogr (2016) 0.82
Computational approaches to selecting and optimising targets for structural biology. Methods (2011) 0.77
XPA: A key scaffold for human nucleotide excision repair. DNA Repair (Amst) (2016) 0.75
C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Nat Genet (2003) 7.25
Protein production and purification. Nat Methods (2008) 3.97
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. Mol Cell (2004) 3.26
Hydroxyl radical-mediated modification of proteins as probes for structural proteomics. Chem Rev (2007) 2.91
Radiolytic protein footprinting with mass spectrometry to probe the structure of macromolecular complexes. Annu Rev Biophys Biomol Struct (2006) 2.14
Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65. Proc Natl Acad Sci U S A (2009) 2.10
Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes. Proc Natl Acad Sci U S A (2010) 2.06
Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors. Proc Natl Acad Sci U S A (2009) 2.01
Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis. J Clin Invest (2005) 1.95
Installation and testing of a focusing mirror at beamline X28C for high flux x-ray radiolysis of biological macromolecules. Rev Sci Instrum (2008) 1.95
Principles of RNA compaction: insights from the equilibrium folding pathway of the P4-P6 RNA domain in monovalent cations. J Mol Biol (2004) 1.90
Vectors for co-expression of an unrestricted number of proteins. Nucleic Acids Res (2007) 1.85
On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr D Biol Crystallogr (2007) 1.78
Genetic analysis of the mouse brain proteome. Nat Genet (2002) 1.73
Probing the structural dynamics of nucleic acids by quantitative time-resolved and equilibrium hydroxyl radical "footprinting". Curr Opin Struct Biol (2002) 1.73
Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5. Blood (2010) 1.72
Radiolytic modification and reactivity of amino acid residues serving as structural probes for protein footprinting. Anal Chem (2005) 1.72
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc Natl Acad Sci U S A (2008) 1.72
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation. Nat Immunol (2011) 1.65
Structural waters define a functional channel mediating activation of the GPCR, rhodopsin. Proc Natl Acad Sci U S A (2009) 1.65
An integrative -omics approach to identify functional sub-networks in human colorectal cancer. PLoS Comput Biol (2010) 1.54
Crystal structure of native RPE65, the retinoid isomerase of the visual cycle. Proc Natl Acad Sci U S A (2009) 1.54
Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme. J Am Chem Soc (2008) 1.50
Concerted binding and bending of DNA by Escherichia coli integration host factor. J Mol Biol (2002) 1.49
Structure-based engineering of strictosidine synthase: auxiliary for alkaloid libraries. Chem Biol (2007) 1.46
Electron microscopic and proteomic comparison of terminal branches of the trigeminal nerve in patients with and without migraine headaches. Plast Reconstr Surg (2014) 1.46
Discovery and scoring of protein interaction subnetworks discriminative of late stage human colon cancer. Mol Cell Proteomics (2008) 1.43
Structural genomics of protein phosphatases. J Struct Funct Genomics (2007) 1.40
Facilities and methods for the high-throughput crystal structural analysis of human proteins. Acc Chem Res (2003) 1.40
Structural proteomics of macromolecular assemblies using oxidative footprinting and mass spectrometry. Trends Biochem Sci (2005) 1.37
Monovalent cations mediate formation of native tertiary structure of the Tetrahymena thermophila ribozyme. Nat Struct Biol (2002) 1.36
The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis. J Biol Chem (2006) 1.34
Alcohol dehydrogenase restricts the ability of the pathogen Candida albicans to form a biofilm on catheter surfaces through an ethanol-based mechanism. Infect Immun (2006) 1.33
Mapping the G-actin binding surface of cofilin using synchrotron protein footprinting. Biochemistry (2002) 1.33
Secondary reactions and strategies to improve quantitative protein footprinting. Anal Chem (2005) 1.32
The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins. Plant Cell (2006) 1.32
Linkage of monovalent and divalent ion binding in the folding of the P4-P6 domain of the Tetrahymena ribozyme. Biochemistry (2002) 1.31
On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength. Acta Crystallogr D Biol Crystallogr (2005) 1.30
Structure and dynamics of the actin filament. Biochemistry (2005) 1.28
The Beamline X28C of the Center for Synchrotron Biosciences: a national resource for biomolecular structure and dynamics experiments using synchrotron footprinting. J Synchrotron Radiat (2007) 1.28
C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain. J Mol Biol (2008) 1.28
An automated method for high-throughput protein purification applied to a comparison of His-tag and GST-tag affinity chromatography. BMC Biotechnol (2003) 1.27
Crystal structure of vinorine synthase, the first representative of the BAHD superfamily. J Biol Chem (2005) 1.26
Monovalent ion-mediated folding of the Tetrahymena thermophila ribozyme. J Mol Biol (2004) 1.24
Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors. J Biol Chem (2003) 1.23
Metalloproteomics: high-throughput structural and functional annotation of proteins in structural genomics. Structure (2005) 1.22
Subnetwork state functions define dysregulated subnetworks in cancer. J Comput Biol (2011) 1.21
Engineering a selectable marker for hyperthermophiles. J Biol Chem (2005) 1.20
Visualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprinting. Proc Natl Acad Sci U S A (2003) 1.18
Structural analysis of gelsolin using synchrotron protein footprinting. Mol Cell Proteomics (2003) 1.18
Future directions of structural mass spectrometry using hydroxyl radical footprinting. J Mass Spectrom (2010) 1.16
Visualizing Arp2/3 complex activation mediated by binding of ATP and WASp using structural mass spectrometry. Proc Natl Acad Sci U S A (2007) 1.16
High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells. BMC Biotechnol (2013) 1.13
Semi-automated, single-band peak-fitting analysis of hydroxyl radical nucleic acid footprint autoradiograms for the quantitative analysis of transitions. Nucleic Acids Res (2004) 1.10
Amorfrutins are potent antidiabetic dietary natural products. Proc Natl Acad Sci U S A (2012) 1.09
Radiolytic modification of sulfur-containing amino acid residues in model peptides: fundamental studies for protein footprinting. Anal Chem (2005) 1.09
Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes. PLoS Pathog (2013) 1.09
The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex. EMBO Rep (2005) 1.08
Radiolytic modification of acidic amino acid residues in peptides: probes for examining protein-protein interactions. Anal Chem (2004) 1.08
On the influence of the incident photon energy on the radiation damage in crystalline biological samples. J Synchrotron Radiat (2005) 1.07
Conformational dynamics of activation for the pentameric complex of dimeric G protein-coupled receptor and heterotrimeric G protein. Structure (2012) 1.07
Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry. Structure (2010) 1.06
Structure of the motor subunit of type I restriction-modification complex EcoR124I. Nat Struct Mol Biol (2008) 1.06
Cyanuric acid hydrolase: evolutionary innovation by structural concatenation. Mol Microbiol (2013) 1.06
Structural insights into the mechanism of protein O-fucosylation. PLoS One (2011) 1.06
Structural allostery and binding of the transferrin*receptor complex. Mol Cell Proteomics (2005) 1.06
Synchrotron protein footprinting supports substrate translocation by ClpA via ATP-induced movements of the D2 loop. Structure (2008) 1.05
Molecular architecture of strictosidine glucosidase: the gateway to the biosynthesis of the monoterpenoid indole alkaloid family. Plant Cell (2007) 1.05
Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum. Structure (2008) 1.05
Crystal structure of Homo sapiens protein hp14.5. Proteins (2004) 1.05
An automated in vitro protein folding screen applied to a human dynactin subunit. Protein Sci (2004) 1.03
Structural mass spectrometry of proteins using hydroxyl radical based protein footprinting. Anal Chem (2011) 1.03
3D-Structure and function of strictosidine synthase--the key enzyme of monoterpenoid indole alkaloid biosynthesis. Plant Physiol Biochem (2008) 1.02
Crystal structure of Escherichia coli L-arabinose isomerase (ECAI), the putative target of biological tagatose production. J Mol Biol (2006) 1.02
Proteomic changes during intestinal cell maturation in vivo. J Proteomics (2008) 1.02
Multiple monovalent ion-dependent pathways for the folding of the L-21 Tetrahymena thermophila ribozyme. J Mol Biol (2003) 1.02
Structural and functional aspects of the sensor histidine kinase PrrB from Mycobacterium tuberculosis. Structure (2006) 1.02
DNA binding provides a molecular strap activating the adenovirus proteinase. Mol Cell Proteomics (2004) 1.01
Integrated algorithms for high-throughput examination of covalently labeled biomolecules by structural mass spectrometry. Anal Chem (2009) 1.00
The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device. Nature (2013) 1.00
X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880. Biol Chem (2004) 1.00
The crystal structure of the herpes simplex virus 1 ssDNA-binding protein suggests the structural basis for flexible, cooperative single-stranded DNA binding. J Biol Chem (2004) 1.00
Proteomics analysis identifies molecular targets related to diabetes mellitus-associated bladder dysfunction. Mol Cell Proteomics (2008) 1.00
Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies. J Struct Funct Genomics (2009) 1.00
The ybeY protein from Escherichia coli is a metalloprotein. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 1.00
Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data. BMC Syst Biol (2012) 1.00
Gene interaction enrichment and network analysis to identify dysregulated pathways and their interactions in complex diseases. BMC Syst Biol (2012) 0.99
Biochemical implications of a three-dimensional model of monomeric actin bound to magnesium-chelated ATP. Structure (2007) 0.99
Network biology methods integrating biological data for translational science. Brief Bioinform (2012) 0.99
New York-Structural GenomiX Research Consortium (NYSGXRC): a large scale center for the protein structure initiative. J Struct Funct Genomics (2005) 0.99
Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis. Proc Natl Acad Sci U S A (2012) 0.99
Structural reorganization of proteins revealed by radiolysis and mass spectrometry: G-actin solution structure is divalent cation dependent. Biochemistry (2003) 0.99
Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis. J Exp Med (2010) 0.99
Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases. Proc Natl Acad Sci U S A (2012) 0.98
Synchrotron radiolysis and mass spectrometry: a new approach to research on the actin cytoskeleton. Acc Chem Res (2004) 0.98
Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data. Proc Natl Acad Sci U S A (2007) 0.98
Structural reorganization of the transferrin C-lobe and transferrin receptor upon complex formation: the C-lobe binds to the receptor helical domain. Biochemistry (2003) 0.97
Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx. BMC Biol (2012) 0.97
Human biomarker discovery and predictive models for disease progression for idiopathic pneumonia syndrome following allogeneic stem cell transplantation. Mol Cell Proteomics (2012) 0.97