PubRank

Lawrence R Gahan

Author PubWeight™ 31.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The catalytic mechanisms of binuclear metallohydrolases. Chem Rev 2006 1.50
2 Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase. Proc Natl Acad Sci U S A 2004 1.12
3 Diesterase activity and substrate binding in purple acid phosphatases. J Am Chem Soc 2007 0.96
4 Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. BMC Struct Biol 2008 0.91
5 Binuclear metallohydrolases: complex mechanistic strategies for a simple chemical reaction. Acc Chem Res 2012 0.90
6 Copper(II) coordination chemistry of westiellamide and its imidazole, oxazole, and thiazole analogues. Chemistry 2008 0.89
7 Synthesis and structural properties of patellamide A derivatives and their copper(II) compounds. Chemistry 2002 0.89
8 Metal-ion mutagenesis: conversion of a purple acid phosphatase from sweet potato to a neutral phosphatase with the formation of an unprecedented catalytically competent Mn(II)Mn(II) active site. J Am Chem Soc 2009 0.86
9 Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. J Am Chem Soc 2008 0.84
10 Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter. J Inorg Biochem 2011 0.83
11 Structural flexibility enhances the reactivity of the bioremediator glycerophosphodiesterase by fine-tuning its mechanism of hydrolysis. J Am Chem Soc 2009 0.82
12 Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme. Protein Eng Des Sel 2011 0.82
13 Formation of mononuclear and chloro-bridged binuclear copper(II) complexes of patellamide D, a naturally occurring cyclic peptide: influence of anion and solvent. J Inorg Biochem 2004 0.82
14 Probing the role of the divalent metal ion in uteroferrin using metal ion replacement and a comparison to isostructural biomimetics. J Biol Inorg Chem 2007 0.81
15 The reaction mechanism of the Ga(III)Zn(II) derivative of uteroferrin and corresponding biomimetics. J Biol Inorg Chem 2007 0.81
16 Synthesis and characterization of the tetranuclear iron(III) complex of a new asymmetric multidentate ligand. A structural model for purple acid phosphatases. Dalton Trans 2007 0.81
17 Spectroscopic characterization of the active Fe(III)Fe(III) and Fe(III)Fe(II) forms of a purple acid phosphatase model system. Inorg Chem 2012 0.80
18 Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme. Biochem J 2010 0.80
19 Phosphate ester cleavage promoted by a tetrameric iron(III) complex. J Biol Inorg Chem 2010 0.79
20 Cyclic peptide marine metabolites and CuII. Dalton Trans 2014 0.79
21 Electronic and geometric structures of the organophosphate-degrading enzyme from Agrobacterium radiobacter (OpdA). J Biol Inorg Chem 2011 0.79
22 The role of Zn-OR and Zn-OH nucleophiles and the influence of para-substituents in the reactions of binuclear phosphatase mimetics. Dalton Trans 2011 0.79
23 Studies of the interaction of potassium(I), calcium(II), magnesium(II), and copper(II) with cyclosporin A. J Inorg Biochem 2003 0.79
24 Structural and catalytic characterization of a heterovalent Mn(II)Mn(III) complex that mimics purple acid phosphatases. Inorg Chem 2009 0.79
25 Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. Inorg Chem 2010 0.79
26 Dinuclear Zn(II) and mixed Cu(II)-Zn(II) complexes of artificial patellamides as phosphatase models. Dalton Trans 2016 0.78
27 The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis. Biochem J 2010 0.78
28 Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes. Dalton Trans 2013 0.77
29 Promiscuity comes at a price: catalytic versatility vs efficiency in different metal ion derivatives of the potential bioremediator GpdQ. Biochim Biophys Acta 2012 0.77
30 Monoesterase activity of a purple acid phosphatase mimic with a cyclam platform. Chemistry 2012 0.77
31 Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH). J Biol Inorg Chem 2014 0.77
32 Synthesis, magnetic properties, and phosphoesterase activity of dinuclear cobalt(II) complexes. Inorg Chem 2013 0.77
33 Cu(II) coordination chemistry of patellamide derivatives: possible biological functions of cyclic pseudopeptides. Chemistry 2012 0.76
34 A new heterobinuclear FeIIICuII complex with a single terminal FeIII-O(phenolate) bond. Relevance to purple acid phosphatases and nucleases. J Biol Inorg Chem 2005 0.76
35 Carbonic anhydrase activity of dinuclear Cu(II) complexes with patellamide model ligands. Dalton Trans 2014 0.76
36 Electronic structure and spectro-structural correlations of Fe(III)Zn(II) biomimetics for purple acid phosphatases: relevance to DNA cleavage and cytotoxic activity. Inorg Chem 2010 0.76
37 The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis. J Inorg Biochem 2009 0.76
38 Unsymmetrical Fe(III)Co(II) and Ga(III)Co(II) complexes as chemical hydrolases: biomimetic models for purple acid phosphatases (PAPs). Inorg Chem 2009 0.76
39 Structural and spectroscopic studies of a model for catechol oxidase. J Biol Inorg Chem 2008 0.75
40 The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis. J Am Chem Soc 2010 0.75
41 Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. J Biol Inorg Chem 2014 0.75
42 Copper(II) complexes of a hexadentate mixed-donor N3S3 macrobicyclic cage: facile rearrangements and interconversions. Chemistry 2010 0.75
43 Reaction mechanism of the metallohydrolase CpsB from Streptococcus pneumoniae, a promising target for novel antimicrobial agents. Dalton Trans 2017 0.75
44 Phosphatase reactivity of a dicopper(II) complex of a patellamide derivative--possible biological functions of cyclic pseudopeptides. Chem Commun (Camb) 2012 0.75
45 Spectroscopic and catalytic characterization of a functional Fe(III)Fe(II) biomimetic for the active site of uteroferrin and protein cleavage. Inorg Chem 2012 0.75
46 Cadmium(II) complexes: mimics of organophosphate pesticide degrading enzymes and metallo-β-lactamases. Inorg Chem 2012 0.75
47 Embracing ligands. Synthesis, characterisation and the correlation between 59Co NMR and ligand field parameters of Co(III) complexes with a new class of nitrogen-thioether multidentate ligand. Dalton Trans 2004 0.75
48 Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand. J Biol Inorg Chem 2008 0.75
49 A structural and catalytic model for zinc phosphoesterases. Dalton Trans 2008 0.75
50 Synthesis, characterization and DFT studies of the cobalt(III) complex of a tetrapodal pentadentate N4S donor ligand. Dalton Trans 2004 0.75
51 Dinuclear zinc(II) complexes with hydrogen bond donors as structural and functional phosphatase models. Inorg Chem 2014 0.75
52 Mechanistic Insight from Calorimetric Measurements of the Assembly of the Binuclear Metal Active Site of Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. Biochemistry 2017 0.75
53 Asymmetric zinc(II) complexes as functional and structural models for phosphoesterases. Dalton Trans 2013 0.75