John J Perona

Author PubWeight™ 45.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 tRNA-dependent active site assembly in a class I aminoacyl-tRNA synthetase. Structure 2003 1.73
2 tRNA-dependent aminoacyl-adenylate hydrolysis by a nonediting class I aminoacyl-tRNA synthetase. J Biol Chem 2005 1.51
3 Distinct kinetic mechanisms of the two classes of Aminoacyl-tRNA synthetases. J Mol Biol 2006 1.49
4 Amino acid discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants. J Mol Biol 2003 1.47
5 Methods for kinetic and thermodynamic analysis of aminoacyl-tRNA synthetases. Methods 2008 1.46
6 DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites. Biochemistry 2004 1.40
7 Aminoacyl-tRNA synthetases: versatile players in the changing theater of translation. RNA 2002 1.29
8 Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei. J Biol Chem 2008 1.29
9 Shape-selective RNA recognition by cysteinyl-tRNA synthetase. Nat Struct Mol Biol 2004 1.25
10 Structure of the Escherichia coli leucine-responsive regulatory protein Lrp reveals a novel octameric assembly. J Mol Biol 2006 1.22
11 Long-range intramolecular signaling in a tRNA synthetase complex revealed by pre-steady-state kinetics. Proc Natl Acad Sci U S A 2004 1.22
12 Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase. EMBO J 2002 1.20
13 Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation. Nat Struct Biol 2002 1.15
14 Partitioning of tRNA-dependent editing between pre- and post-transfer pathways in class I aminoacyl-tRNA synthetases. J Biol Chem 2010 1.11
15 Amino acid-dependent transfer RNA affinity in a class I aminoacyl-tRNA synthetase. J Biol Chem 2005 1.07
16 Simultaneous DNA binding and bending by EcoRV endonuclease observed by real-time fluorescence. Biochemistry 2003 1.06
17 Zinc-mediated amino acid discrimination in cysteinyl-tRNA synthetase. J Mol Biol 2003 1.05
18 Exploring writhe in supercoiled minicircle DNA. J Phys Condens Matter 2006 1.03
19 The homotetrameric phosphoseryl-tRNA synthetase from Methanosarcina mazei exhibits half-of-the-sites activity. J Biol Chem 2008 1.01
20 Kinetic partitioning between synthetic and editing pathways in class I aminoacyl-tRNA synthetases occurs at both pre-transfer and post-transfer hydrolytic steps. J Biol Chem 2012 1.00
21 Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5. RNA 2010 0.99
22 Structural and mechanistic basis for enhanced translational efficiency by 2-thiouridine at the tRNA anticodon wobble position. J Mol Biol 2013 0.98
23 Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14. Nucleic Acids Res 2011 0.96
24 Structural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetase. Nucleic Acids Res 2011 0.96
25 Stereochemical mechanisms of tRNA methyltransferases. FEBS Lett 2010 0.96
26 A rationally engineered misacylating aminoacyl-tRNA synthetase. Proc Natl Acad Sci U S A 2008 0.93
27 Amino acid discrimination by a highly differentiated metal center of an aminoacyl-tRNA synthetase. Biochemistry 2003 0.91
28 Heat maps for intramolecular communication in an RNP enzyme encoding glutamine. Structure 2011 0.90
29 Kinetic quality control of anticodon recognition by a eukaryotic aminoacyl-tRNA synthetase. J Mol Biol 2007 0.89
30 Active-site assembly in glutaminyl-tRNA synthetase by tRNA-mediated induced fit. Biochemistry 2006 0.87
31 Synthesis of Glu-tRNA(Gln) by engineered and natural aminoacyl-tRNA synthetases. Biochemistry 2010 0.86
32 Two-step aminoacylation of tRNA without channeling in Archaea. J Mol Biol 2011 0.85
33 Electrostatic contributions to site specific DNA cleavage by EcoRV endonuclease. Biochemistry 2002 0.84
34 Non-cognate enzyme-DNA complex: structural and kinetic analysis of EcoRV endonuclease bound to the EcoRI recognition site GAATTC. J Mol Biol 2005 0.84
35 Kinetics of tRNA folding monitored by aminoacylation. RNA 2012 0.84
36 The energetic contribution of induced electrostatic asymmetry to DNA bending by a site-specific protein. J Mol Biol 2010 0.83
37 Novel proteins for homocysteine biosynthesis in anaerobic microorganisms. Mol Microbiol 2014 0.80
38 Structural dynamics of a mitochondrial tRNA possessing weak thermodynamic stability. Biochemistry 2014 0.80
39 Architectural underpinnings of the genetic code for glutamine. Biochemistry 2009 0.80
40 Determinants for tRNA-dependent pretransfer editing in the synthetic site of isoleucyl-tRNA synthetase. Biochemistry 2014 0.79
41 Engineered extrahelical base destabilization enhances sequence discrimination of DNA methyltransferase M.HhaI. J Mol Biol 2006 0.79
42 Linking energy production and protein synthesis in hydrogenotrophic methanogens. Biochemistry 2012 0.78
43 Recoding aminoacyl-tRNA synthetases for synthetic biology by rational protein-RNA engineering. ACS Chem Biol 2014 0.78
44 Positively charged C-terminal subdomains of EcoRV endonuclease: contributions to DNA binding, bending, and cleavage. Biochemistry 2006 0.77
45 Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection. Org Biomol Chem 2017 0.75