Published in Cancer Res on February 01, 2008
Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action. Biochim Biophys Acta (2013) 1.90
The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis. Cancer Res (2009) 1.88
Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements. Cell Mol Life Sci (2010) 1.58
miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer. J Pathol (2013) 1.56
The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes. Oncogene (2010) 1.43
HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay. Mol Cell Biol (2010) 1.35
Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation. Nucleic Acids Res (2009) 1.35
The role of tristetraprolin in cancer and inflammation. Front Biosci (Landmark Ed) (2012) 1.33
The roles of TTP and BRF proteins in regulated mRNA decay. Wiley Interdiscip Rev RNA (2011) 1.24
The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase. Aging (Albany NY) (2009) 1.14
Tristetraprolin regulates interleukin-6, which is correlated with tumor progression in patients with head and neck squamous cell carcinoma. Cancer (2011) 1.12
Interleukins in glioblastoma pathophysiology: implications for therapy. Br J Pharmacol (2013) 1.07
Tristetraprolin: roles in cancer and senescence. Ageing Res Rev (2012) 1.03
Stability of the LATS2 tumor suppressor gene is regulated by tristetraprolin. J Biol Chem (2010) 1.01
Inactivation or loss of TTP promotes invasion in head and neck cancer via transcript stabilization and secretion of MMP9, MMP2, and IL-6. Clin Cancer Res (2013) 0.98
CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin. PLoS One (2014) 0.97
Perspectives on the ARE as it turns 25 years old. Wiley Interdiscip Rev RNA (2012) 0.97
Inflammation: cytokines and RNA-based regulation. Wiley Interdiscip Rev RNA (2010) 0.92
Gene regulation by RNA binding proteins and microRNAs in angiogenesis. Trends Mol Med (2011) 0.91
Genetic polymorphisms in RNA binding proteins contribute to breast cancer survival. Int J Cancer (2012) 0.88
RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting. J Interferon Cytokine Res (2014) 0.88
Transforming growth factor β regulates P-body formation through induction of the mRNA decay factor tristetraprolin. Mol Cell Biol (2013) 0.86
mRNA-binding protein ZFP36 is expressed in atherosclerotic lesions and reduces inflammation in aortic endothelial cells. Arterioscler Thromb Vasc Biol (2013) 0.85
p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion. J Biol Chem (2014) 0.84
Mutant copper-zinc superoxide dismutase associated with amyotrophic lateral sclerosis binds to adenine/uridine-rich stability elements in the vascular endothelial growth factor 3'-untranslated region. J Neurochem (2009) 0.84
Casein kinase 2 regulates the mRNA-destabilizing activity of tristetraprolin. J Biol Chem (2011) 0.84
Selective upregulation of interleukin-8 by human rhabdomyosarcomas in response to hypoxia: therapeutic implications. Int J Cancer (2010) 0.83
Fumaric acid esters stimulate astrocytic VEGF expression through HIF-1α and Nrf2. PLoS One (2013) 0.82
The G protein-coupled receptor GALR2 promotes angiogenesis in head and neck cancer. Mol Cancer Ther (2014) 0.82
ZFP36L1 negatively regulates erythroid differentiation of CD34+ hematopoietic stem cells by interfering with the Stat5b pathway. Mol Biol Cell (2010) 0.81
Mutant tristetraprolin: a potent inhibitor of malignant glioma cell growth. J Neurooncol (2013) 0.81
Tristetraprolin induces cell cycle arrest in breast tumor cells through targeting AP-1/c-Jun and NF-κB pathway. Oncotarget (2015) 0.81
Anthrax lethal toxin promotes dephosphorylation of TTP and formation of processing bodies. Cell Microbiol (2009) 0.80
Regulation of the mRNA half-life in breast cancer. World J Clin Oncol (2014) 0.80
Resveratrol Induces Glioma Cell Apoptosis through Activation of Tristetraprolin. Mol Cells (2015) 0.79
Hallmarks of cancer and AU-rich elements. Wiley Interdiscip Rev RNA (2016) 0.78
Drosophila eyes absent is a novel mRNA target of the tristetraprolin (TTP) protein DTIS11. Int J Biol Sci (2012) 0.78
Tristetraprolin inhibits the growth of human glioma cells through downregulation of urokinase plasminogen activator/urokinase plasminogen activator receptor mRNAs. Mol Cells (2014) 0.78
Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: prognostic value and impact on gene expression. Mol Cancer (2015) 0.77
IL-17 attenuates degradation of ARE-mRNAs by changing the cooperation between AU-binding proteins and microRNA16. PLoS Genet (2013) 0.76
Post-transcriptional regulation of cytokine and growth factor signaling in cancer. Cytokine Growth Factor Rev (2016) 0.75
The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases. Biochem Soc Trans (2016) 0.75
RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss. Oncotarget (2016) 0.75
Inactivation of tristetraprolin in chronic hypoxia provokes the expression of cathepsin B. Mol Cell Biol (2014) 0.75
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses. Nat Commun (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity (2009) 7.69
Human cytomegalovirus infection and expression in human malignant glioma. Cancer Res (2002) 4.58
Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature (2012) 4.13
Oxidative damage-induced inflammation initiates age-related macular degeneration. Nat Med (2008) 3.92
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell (2009) 3.34
Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer. J Immunother (2013) 2.80
Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure. J Clin Invest (2005) 2.75
Stepping and stretching. How kinesin uses internal strain to walk processively. J Biol Chem (2003) 2.60
Fracture resistance and histological findings of immature teeth treated with mineral trioxide aggregate. Dent Traumatol (2008) 2.50
Inhibition of cystine uptake disrupts the growth of primary brain tumors. J Neurosci (2005) 2.17
Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy. Science (2009) 2.13
Predictive value of serum HER2 ECD in patients with HER2-positive advanced gastric cancer treated with trastuzumab plus chemotherapy. J Gastroenterol (2015) 2.01
VA opsin-based photoreceptors in the hypothalamus of birds. Curr Biol (2009) 2.01
Impact of the time interval between MDCT imaging and surgery on the accuracy of identifying metastatic disease in patients with pancreatic cancer. AJR Am J Roentgenol (2015) 2.00
Molecular design of 1,2,4,5-tetrazine-based high-energy density materials. J Phys Chem A (2009) 1.86
An animal model for studying the pathogenesis of chikungunya virus infection. Am J Trop Med Hyg (2008) 1.83
Retracted Intragastric exposure to titanium dioxide nanoparticles induced nephrotoxicity in mice, assessed by physiological and gene expression modifications. Part Fibre Toxicol (2013) 1.80
Spatial and temporal distribution of falciparum malaria in China. Malar J (2009) 1.79
The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation. Nucleic Acids Res (2005) 1.76
Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochem Pharmacol (2010) 1.69
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis. Proc Natl Acad Sci U S A (2011) 1.69
Statins may aggravate myasthenia gravis. Muscle Nerve (2008) 1.66
Erythropoietin receptor signalling is required for normal brain development. Development (2002) 1.65
CD133 is a marker of bioenergetic stress in human glioma. PLoS One (2008) 1.63
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity. Mol Brain (2008) 1.61
Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration. Proc Natl Acad Sci U S A (2006) 1.59
The impact of postoperative complications on the administration of adjuvant therapy following pancreaticoduodenectomy for adenocarcinoma. Ann Surg Oncol (2014) 1.58
Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5. Int J Radiat Oncol Biol Phys (2008) 1.56
Phase 2 multi-institutional trial evaluating gemcitabine and stereotactic body radiotherapy for patients with locally advanced unresectable pancreatic adenocarcinoma. Cancer (2014) 1.55
Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts. Clin Cancer Res (2006) 1.54
Catecholamines regulate the activity, secretion, and synthesis of renalase. Circulation (2008) 1.54
Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression. Clin Cancer Res (2008) 1.52
Molecular mechanism of titanium dioxide nanoparticles-induced oxidative injury in the brain of mice. Chemosphere (2013) 1.51
Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal function. Curr Biol (2006) 1.47
Derivation of a benchmark for freshwater ionic strength. Environ Toxicol Chem (2012) 1.46
Characterization of celastrol to inhibit hsp90 and cdc37 interaction. J Biol Chem (2009) 1.45
The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes. Cell Metab (2013) 1.45
Predicting fetal acidemia using umbilical venous cord gas parameters. Obstet Gynecol (2014) 1.42
The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight. Hum Mol Genet (2003) 1.40
Acid-sensing ion channels in malignant gliomas. J Biol Chem (2003) 1.38
The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity. Proc Natl Acad Sci U S A (2004) 1.37
Dengue virus serotype 3 subtype III, Zhejiang Province, China. Emerg Infect Dis (2011) 1.37
Oxygen tension in the rabbit lens and vitreous before and after vitrectomy. Exp Eye Res (2004) 1.36
PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors. J Immunother (2015) 1.35
Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation. J Biol Chem (2002) 1.34
An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance. J Biol Chem (2006) 1.33
Characteristics of long non-coding RNA and its relation to hepatocellular carcinoma. Carcinogenesis (2013) 1.33
Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane. Biochemistry (2007) 1.33
Fibroblast growth factor receptors as molecular targets in thyroid carcinoma. Endocrinology (2004) 1.31
Docking and rolling, a model of how the mitotic motor Eg5 works. J Biol Chem (2005) 1.30
Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. J Biol Chem (2010) 1.30
Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease. J Biol Chem (2004) 1.30
Bacterial biosynthesis and maturation of the didemnin anti-cancer agents. J Am Chem Soc (2012) 1.29
Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells. Cancer Res (2005) 1.29
Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines. J Neurooncol (2005) 1.29
Oncolytic viruses: clinical applications as vectors for the treatment of malignant gliomas. J Neurooncol (2003) 1.28
Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples. Cancer Res (2002) 1.26
Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro Oncol (2005) 1.26
Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor. J Biol Chem (2004) 1.24
Retracted Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis. J Clin Invest (2002) 1.24
Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease. J Gastroenterol Hepatol (2008) 1.24
Pyrolytic characteristics and kinetics of two brown algae and sodium alginate. Bioresour Technol (2010) 1.24
IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR. Int J Cancer (2005) 1.23
The Association Between Chemoradiation-related Lymphopenia and Clinical Outcomes in Patients With Locally Advanced Pancreatic Adenocarcinoma. Am J Clin Oncol (2015) 1.23
Functional diversity of melanopsins and their global expression in the teleost retina. Cell Mol Life Sci (2011) 1.23
Measuring kinesin's first step. J Biol Chem (2002) 1.23
Therapeutic potential of AZD1480 for the treatment of human glioblastoma. Mol Cancer Ther (2011) 1.22
Differential expression of two distinct functional isoforms of melanopsin (Opn4) in the mammalian retina. J Neurosci (2009) 1.22
MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration. J Neurosci (2013) 1.21
Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer. JAMA (2009) 1.21
Molecular epidemiology of measles viruses in China, 1995-2003. Virol J (2007) 1.20
Novel DNA-binding properties of the RNA-binding protein TIAR. Nucleic Acids Res (2005) 1.20
Tumor necrosis factor alpha induces angiogenic factor up-regulation in malignant glioma cells: a role for RNA stabilization and HuR. Cancer Res (2003) 1.19
Urinary tubular biomarkers in short-term type 2 diabetes mellitus patients: a cross-sectional study. Endocrine (2011) 1.19
6-Cyclo-hexyl-6,7-dihydro-dibenzo[c,f][1,5]aza-bis-mocin-12(5H)-yl(N→Bi) trifluoro-methane-sulfonate. Acta Crystallogr Sect E Struct Rep Online (2011) 1.17
Epigenetically controlled fibroblast growth factor receptor 2 signaling imposes on the RAS/BRAF/mitogen-activated protein kinase pathway to modulate thyroid cancer progression. Cancer Res (2007) 1.16
The RNA-binding protein HuR promotes glioma growth and treatment resistance. Mol Cancer Res (2011) 1.16
Lysosome dysfunction triggers Atg7-dependent neural apoptosis. J Biol Chem (2010) 1.16
Validation of reference genes for gene expression studies in peanut by quantitative real-time RT-PCR. Mol Genet Genomics (2011) 1.15
Identification of miRNA from Porphyra yezoensis by high-throughput sequencing and bioinformatics analysis. PLoS One (2010) 1.15
Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells. J Biol Chem (2006) 1.15
Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status. J Biol Chem (2008) 1.15
Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas. Cancer Res (2002) 1.14
The improvement of spinach growth by nano-anatase TiO2 treatment is related to nitrogen photoreduction. Biol Trace Elem Res (2007) 1.14
Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production. PLoS One (2011) 1.14
Distribution of Aedes albopictus (Diptera: Culicidae) in northwestern China. Vector Borne Zoonotic Dis (2011) 1.12
Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner. PLoS One (2012) 1.11
Selection of optimal reference genes for normalization in quantitative RT-PCR. BMC Bioinformatics (2010) 1.11
Biocompatible polypyrrole nanoparticles as a novel organic photoacoustic contrast agent for deep tissue imaging. Nanoscale (2013) 1.11
A multicenter analysis of GTX chemotherapy in patients with locally advanced and metastatic pancreatic adenocarcinoma. Cancer Chemother Pharmacol (2011) 1.09
Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts. Mol Cell Biol (2004) 1.08
Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells. Cancer Res (2006) 1.07
Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction. J Neurochem (2010) 1.07
Development of novel tetravalent anti-CD20 antibodies with potent antitumor activity. Cancer Res (2008) 1.07
Smad4 as a transcription corepressor for estrogen receptor alpha. J Biol Chem (2003) 1.07