John Tower

Author PubWeight™ 61.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster. Proc Natl Acad Sci U S A 2004 2.94
3 Increased internal and external bacterial load during Drosophila aging without life-span trade-off. Cell Metab 2007 2.82
4 Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics 2002 2.22
5 Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes. Genome Biol 2007 2.12
6 Superoxide dismutase evolution and life span regulation. Mech Ageing Dev 2005 2.02
7 Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone. Exp Gerontol 2007 1.51
8 O fly, where art thou? J R Soc Interface 2008 1.50
9 Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span. Mech Ageing Dev 2004 1.33
10 Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster. Aging (Albany NY) 2012 1.21
11 Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy. Aging (Albany NY) 2009 1.19
12 Hydrogen peroxide stimulates activity and alters behavior in Drosophila melanogaster. PLoS One 2009 1.15
13 A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila. Aging (Albany NY) 2009 1.14
14 Conditional inhibition of autophagy genes in adult Drosophila impairs immunity without compromising longevity. Exp Gerontol 2008 1.10
15 Expression of hsp22 and hsp70 transgenes is partially predictive of drosophila survival under normal and stress conditions. J Gerontol A Biol Sci Med Sci 2009 1.10
16 Three-dimensional tracking and behaviour monitoring of multiple fruit flies. J R Soc Interface 2012 1.02
17 Simultaneous tracking of fly movement and gene expression using GFP. BMC Biotechnol 2008 1.02
18 A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes. Genome Biol 2003 0.98
19 A conserved role for the 20S proteasome and Nrf2 transcription factor in oxidative stress adaptation in mammals, Caenorhabditis elegans and Drosophila melanogaster. J Exp Biol 2012 0.96
20 Drosophila foxo acts in males to cause sexual-dimorphism in tissue-specific p53 life span effects. Exp Gerontol 2009 0.93
21 Oxidative stress adaptation with acute, chronic, and repeated stress. Free Radic Biol Med 2012 0.91
22 Adult-specific over-expression of the Drosophila genes magu and hebe increases life span and modulates late-age female fecundity. Mol Genet Genomics 2008 0.91
23 Doxycycline-regulated over-expression of hsp22 has negative effects on stress resistance and life span in adult Drosophila melanogaster. Mech Ageing Dev 2004 0.90
24 Impact papers on aging in 2009. Aging (Albany NY) 2010 0.89
25 Stem cell aging in the Drosophila ovary. Age (Dordr) 2005 0.88
26 Simultaneous tracking of movement and gene expression in multiple Drosophila melanogaster flies using GFP and DsRED fluorescent reporter transgenes. BMC Res Notes 2009 0.88
27 Doxycycline-induced expression of sense and inverted-repeat constructs modulates phosphogluconate mutase (Pgm) gene expression in adult Drosophila melanogaster. Genome Biol 2002 0.88
28 Sequence requirements for function of the Drosophila chorion gene locus ACE3 replicator and ori-beta origin elements. Development 2004 0.86
29 Identifying sexual differentiation genes that affect Drosophila life span. BMC Geriatr 2009 0.84
30 The genetic architecture of aging: sexual antagonistic pleiotropy of p53 and foxo. Cell Cycle 2010 0.84
31 Conditional switches for extracellular matrix patterning in Drosophila melanogaster. Genetics 2008 0.83
32 Aging, MnSOD, and hormesis mechanisms converge on liver mUPR. Cell Cycle 2013 0.81
33 Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster. Exp Gerontol 2010 0.81
34 Programmed cell death and apoptosis in aging and life span regulation. Discov Med 2009 0.80
35 Using GFP video to track 3D movement and conditional gene expression in free-moving flies. PLoS One 2012 0.78
36 Assessing senescence in Drosophila using video tracking. Methods Mol Biol 2013 0.78
37 Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster. Aging (Albany NY) 2011 0.75