Published in Int J Hematol on February 07, 2008
H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science (2008) 7.89
Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function. Proc Natl Acad Sci U S A (2011) 1.82
Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2. Antioxid Redox Signal (2013) 1.79
Sustained normalization of high blood pressure in spontaneously hypertensive rats by implanted hemin pump. Hypertension (2006) 1.71
Pro-apoptotic effect of endogenous H2S on human aorta smooth muscle cells. FASEB J (2006) 1.62
Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms. J Physiol (2005) 1.59
H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells. J Biol Chem (2007) 1.56
Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1. J Biol Chem (2004) 1.56
Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production. Proc Natl Acad Sci U S A (2012) 1.49
Differentiation and hematopoietic-support of clonal cells in myelodysplastic syndromes. Leuk Lymphoma (2007) 1.49
Increased expression of calcium-sensing receptors induced by ox-LDL amplifies apoptosis of cardiomyocytes during simulated ischaemia-reperfusion. Clin Exp Pharmacol Physiol (2010) 1.45
Direct stimulation of K(ATP) channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells. Mol Pharmacol (2005) 1.35
Interaction of hydrogen sulfide with ion channels. Clin Exp Pharmacol Physiol (2010) 1.34
Effects of hydrogen sulfide on homocysteine-induced oxidative stress in vascular smooth muscle cells. Biochem Biophys Res Commun (2006) 1.31
Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose. Br J Pharmacol (2010) 1.31
Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells. Cardiovasc Res (2010) 1.31
Molecular mechanism for H(2)S-induced activation of K(ATP) channels. Antioxid Redox Signal (2010) 1.28
Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis. Circulation (2013) 1.26
Predicting DNA- and RNA-binding proteins from sequences with kernel methods. J Theor Biol (2009) 1.23
Oxidative stress in hypertension. Clin Exp Hypertens (2005) 1.23
Oxidative stress and aging: is methylglyoxal the hidden enemy? Can J Physiol Pharmacol (2010) 1.16
Protective effect of hydrogen sulfide on balloon injury-induced neointima hyperplasia in rat carotid arteries. Am J Pathol (2007) 1.13
Lipoic acid prevents hypertension, hyperglycemia, and the increase in heart mitochondrial superoxide production. Am J Hypertens (2003) 1.12
Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring. Ann Hematol (2010) 1.11
Calcium and polyamine regulated calcium-sensing receptors in cardiac tissues. Eur J Biochem (2003) 1.09
Methylglyoxal, protein binding and biological samples: are we getting the true measure? J Chromatogr B Analyt Technol Biomed Life Sci (2009) 1.09
Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats. Diabetes (2011) 1.06
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats. J Hypertens (2008) 1.06
Oxygen-sensitive mitochondrial accumulation of cystathionine β-synthase mediated by Lon protease. Proc Natl Acad Sci U S A (2013) 1.06
Methylglyoxal production in vascular smooth muscle cells from different metabolic precursors. Metabolism (2008) 1.04
Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats. Mol Cell Biochem (2007) 1.03
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats. Kidney Int (2004) 1.01
Hydrogen sulfide and the pathogenesis of atherosclerosis. Antioxid Redox Signal (2013) 1.01
Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clin Biochem (2007) 1.00
Vascular methylglyoxal metabolism and the development of hypertension. J Hypertens (2005) 1.00
Free radical generation by methylglyoxal in tissues. Drug Metabol Drug Interact (2008) 0.99
Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells. Free Radic Biol Med (2005) 0.99
Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats. Br J Pharmacol (2009) 0.98
Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome. Cardiovasc Res (2011) 0.98
Methylglyoxal and advanced glycation endproducts: new therapeutic horizons? Recent Pat Cardiovasc Drug Discov (2007) 0.98
Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats. Nutr Res (2008) 0.98
Structural and functional changes in human insulin induced by methylglyoxal. FASEB J (2006) 0.98
H₂S is an endothelium-derived hyperpolarizing factor. Antioxid Redox Signal (2013) 0.97
Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells. Biochem Pharmacol (2009) 0.96
Increased neointimal formation in cystathionine gamma-lyase deficient mice: role of hydrogen sulfide in α5β1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells. J Mol Cell Cardiol (2011) 0.95
Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats. Blood (2002) 0.95
The pathogenic role of cystathionine γ-lyase/hydrogen sulfide in streptozotocin-induced diabetes in mice. Am J Pathol (2011) 0.93
The role of endothelial cell adhesion molecules P-selectin, E-selectin and intercellular adhesion molecule-1 in leucocyte recruitment induced by exogenous methylglyoxal. Immunology (2012) 0.91
Altered expression of BK channel beta1 subunit in vascular tissues from spontaneously hypertensive rats. Am J Hypertens (2006) 0.90
Methylglyoxal mediates adipocyte proliferation by increasing phosphorylation of Akt1. PLoS One (2012) 0.90
Methylglyoxal, oxidative stress, and hypertension. Can J Physiol Pharmacol (2006) 0.90
Efficacy and safety of CHG regimen (low-dose cytarabine, homoharringtonine with G-CSF priming) as induction chemotherapy for elderly patients with high-risk MDS or AML transformed from MDS. J Cancer Res Clin Oncol (2011) 0.89
Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells. Toxicol Appl Pharmacol (2011) 0.89
Dietary approaches to positively influence fetal determinants of adult health. FASEB J (2005) 0.89
Fructose-induced peroxynitrite production is mediated by methylglyoxal in vascular smooth muscle cells. Life Sci (2006) 0.88
Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α. Br J Pharmacol (2012) 0.87
Exogenous hydrogen sulfide attenuates diabetic myocardial injury through cardiac mitochondrial protection. Mol Cell Biochem (2012) 0.87
Attenuation of hypertension development by aminoguanidine in spontaneously hypertensive rats: role of methylglyoxal. Am J Hypertens (2007) 0.86
Effect of low-dose cytarabine, homoharringtonine and granulocyte colony-stimulating factor priming regimen on patients with advanced myelodysplastic syndrome or acute myeloid leukemia transformed from myelodysplastic syndrome. Leuk Lymphoma (2009) 0.86
N-acetylcysteine improves nitric oxide and alpha-adrenergic pathways in mesenteric beds of spontaneously hypertensive rats. Am J Hypertens (2003) 0.85
Melatonin alleviates secondary brain damage and neurobehavioral dysfunction after experimental subarachnoid hemorrhage: possible involvement of TLR4-mediated inflammatory pathway. J Pineal Res (2013) 0.85
Modulation of cardiac and aortic peroxisome proliferator-activated receptor-gamma expression by oxidative stress in chronically glucose-fed rats. Am J Hypertens (2006) 0.85
Interaction of hydrogen sulfide and estrogen on the proliferation of vascular smooth muscle cells. PLoS One (2012) 0.85
Impaired osteogenic differentiation of mesenchymal stem cells derived from bone marrow of patients with lower-risk myelodysplastic syndromes. Tumour Biol (2014) 0.84
Activated human umbilical cord blood dendritic cells kill tumor cells without damaging normal hematological progenitor cells. Cancer Sci (2005) 0.84
Arginine attenuates methylglyoxal- and high glucose-induced endothelial dysfunction and oxidative stress by an endothelial nitric-oxide synthase-independent mechanism. J Pharmacol Exp Ther (2012) 0.84
Senescence of bone marrow mesenchymal stromal cells is accompanied by activation of p53/p21 pathway in myelodysplastic syndromes. Eur J Haematol (2014) 0.84
Inhibition of vascular smooth muscle cell proliferation by chronic hemin treatment. Am J Physiol Heart Circ Physiol (2008) 0.84
Xenogeneic immunosuppression of human umbilical cord mesenchymal stem cells in a major histocompatibility complex-mismatched allogeneic acute graft-versus-host disease murine model. Eur J Haematol (2011) 0.84
Cytogenetic response based on revised IPSS cytogenetic risk stratification and minimal residual disease monitoring by FISH in MDS patients treated with low-dose decitabine. Leuk Res (2013) 0.84
Modification of Akt1 by methylglyoxal promotes the proliferation of vascular smooth muscle cells. FASEB J (2011) 0.83
Increased methylglyoxal formation with upregulation of renin angiotensin system in fructose fed Sprague Dawley rats. PLoS One (2013) 0.83
Interaction of methylglyoxal and hydrogen sulfide in rat vascular smooth muscle cells. Antioxid Redox Signal (2010) 0.83
Modulation of methylglyoxal and glutathione by soybean isoflavones in mild streptozotocin-induced diabetic rats. Nutr Metab Cardiovasc Dis (2007) 0.82
Flow cytometric scoring system (FCMSS) assisted diagnosis of myelodysplastic syndromes (MDS) and the biological significance of FCMSS-based immunophenotypes. Br J Haematol (2010) 0.82
Aldolase B knockdown prevents high glucose-induced methylglyoxal overproduction and cellular dysfunction in endothelial cells. PLoS One (2012) 0.81
Interaction of selective amino acid residues of K(ca) channels with carbon monoxide. Exp Biol Med (Maywood) (2003) 0.81
Methylglyoxal modulates endothelial nitric oxide synthase-associated functions in EA.hy926 endothelial cells. Cardiovasc Diabetol (2013) 0.80
Uncoupling of eNOS contributes to redox-sensitive leukocyte recruitment and microvascular leakage elicited by methylglyoxal. Biochem Pharmacol (2013) 0.80
The dietary phase 2 protein inducer sulforaphane can normalize the kidney epigenome and improve blood pressure in hypertensive rats. Am J Hypertens (2011) 0.80
The biological behavior of SDF-1/CXCR4 in patients with myelodysplastic syndrome. Med Oncol (2011) 0.80
A delayed yet durable response to very short lenalidomide therapy and unexpected clone redistribution in a case of myelodysplastic syndrome with del(5q) and del(20q). Leuk Res (2009) 0.80
Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes. Endocrinology (2012) 0.80
Hydrogen sulfide represses androgen receptor transactivation by targeting at the second zinc finger module. J Biol Chem (2014) 0.80
Methylation of the p73 gene in patients with myelodysplastic syndromes: correlations with apoptosis and prognosis. Tumour Biol (2012) 0.79
Sulphonylureas induced vasorelaxation of mouse arteries. Eur J Pharmacol (2007) 0.79
Interleukin-17 enhances the production of interferon-γ and tumour necrosis factor-α by bone marrow T lymphocytes from patients with lower risk myelodysplastic syndromes. Eur J Haematol (2013) 0.79
Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats. Can J Physiol Pharmacol (2011) 0.79
Hydrogen sulfide and the metabolic syndrome. Expert Rev Clin Pharmacol (2011) 0.79
Low RPS14 expression in MDS without 5q - aberration confers higher apoptosis rate of nucleated erythrocytes and predicts prolonged survival and possible response to lenalidomide in lower risk non-5q- patients. Eur J Haematol (2013) 0.78