Published in Ann Hematol on December 02, 2010
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EZH2 in normal and malignant hematopoiesis. Leukemia (2013) 1.28
Retracted Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease. Nat Commun (2012) 1.24
EZH2: not EZHY (easy) to deal. Mol Cancer Res (2014) 1.20
Context-dependent actions of Polycomb repressors in cancer. Oncogene (2015) 0.89
Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes. Oncotarget (2015) 0.88
Epigenetic therapy of acute myeloid leukemia using 5-aza-2'-deoxycytidine (decitabine) in combination with inhibitors of histone methylation and deacetylation. Clin Epigenetics (2014) 0.86
Epigenetic alterations and microRNAs: new players in the pathogenesis of myelodysplastic syndromes. Epigenetics (2013) 0.84
Digging deep into "dirty" drugs - modulation of the methylation machinery. Drug Metab Rev (2015) 0.83
Identification of epigenetic modifications that contribute to pathogenesis in therapy-related AML: Effective integration of genome-wide histone modification with transcriptional profiles. BMC Med Genomics (2015) 0.81
The need for additional genetic markers for myelodysplastic syndrome stratification: what does the future hold for prognostication? Expert Rev Hematol (2013) 0.81
EZH2 in normal hematopoiesis and hematological malignancies. Oncotarget (2016) 0.81
Why methylation is not a marker predictive of response to hypomethylating agents. Haematologica (2014) 0.79
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. J Biol Chem (2015) 0.79
Mutated Chromatin Regulatory Factors as Tumor Drivers in Cancer. Cancer Res (2017) 0.79
Epigenetic regulators and their impact on therapy in acute myeloid leukemia. Haematologica (2016) 0.78
H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer. Adv Cancer Res (2016) 0.78
Genomic loss of EZH2 leads to epigenetic modifications and overexpression of the HOX gene clusters in myelodysplastic syndrome. Oncotarget (2016) 0.78
Distinct clinical and experimental characteristics in the patients younger than 60 years old with myelodysplastic syndromes. PLoS One (2013) 0.77
Histone methylation in myelodysplastic syndromes. Epigenomics (2011) 0.77
Decitabine of reduced dosage in Chinese patients with myelodysplastic syndrome: a retrospective analysis. PLoS One (2014) 0.77
Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2. Oncotarget (2016) 0.76
Quantitative Detection of ID4 Gene Aberrant Methylation in the Differentiation of Myelodysplastic Syndrome from Aplastic Anemia. Chin Med J (Engl) (2015) 0.75
Notable roles of EZH2 and DNMT1 in epigenetic dormancy of the SHP1 gene during the progression of chronic myeloid leukaemia. Oncol Lett (2017) 0.75
DNA Methylation Events as Markers for Diagnosis and Management of Acute Myeloid Leukemia and Myelodysplastic Syndrome. Dis Markers (2017) 0.75
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Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding. Genome Res (2009) 15.15
Genomewide association study of leprosy. N Engl J Med (2009) 8.17
Rapid whole-genome mutational profiling using next-generation sequencing technologies. Genome Res (2008) 8.01
H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science (2008) 7.89
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
A compendium of RNA-binding motifs for decoding gene regulation. Nature (2013) 4.91
The global burden of liver disease: the major impact of China. Hepatology (2014) 4.23
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet (2009) 3.59
Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients. Gastroenterology (2007) 3.34
Peginterferon alfa-2b therapy in acute hepatitis C: impact of onset of therapy on sustained virologic response. Gastroenterology (2006) 2.96
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors. Blood (2007) 2.93
Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell (2012) 2.71
A randomized controlled trial of Licartin for preventing hepatoma recurrence after liver transplantation. Hepatology (2007) 2.66
Interleukin-17-producing CD4(+) T cells increase with severity of liver damage in patients with chronic hepatitis B. Hepatology (2010) 2.44
Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial. Eur Urol (2012) 2.34
Messenger RNA expression levels of CXCR4 correlate with metastatic behavior and outcome in patients with osteosarcoma. Clin Cancer Res (2005) 2.31
Sequence variants at 22q13 are associated with prostate cancer risk. Cancer Res (2009) 2.27
Meta-analysis of randomised controlled trials comparing unipolar with bipolar hemiarthroplasty for displaced femoral-neck fractures. Int Orthop (2014) 2.06
Different cystic fibrosis transmembrane conductance regulator mutations in Chinese men with congenital bilateral absence of vas deferens and other acquired obstructive azoospermia. Urology (2013) 2.01
Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma. Clin Cancer Res (2006) 1.97
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. J Exp Med (2007) 1.93
Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway. Cancer Res (2004) 1.93
Fine mapping association study and functional analysis implicate a SNP in MSMB at 10q11 as a causal variant for prostate cancer risk. Hum Mol Genet (2009) 1.90
Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation. Mol Cell Biol (2002) 1.89
BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate-treated patients with CML. Blood (2006) 1.89
Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function. Proc Natl Acad Sci U S A (2011) 1.82
Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2. Antioxid Redox Signal (2013) 1.79
Two independent prostate cancer risk-associated Loci at 11q13. Cancer Epidemiol Biomarkers Prev (2009) 1.78
Impairment of CD4+ cytotoxic T cells predicts poor survival and high recurrence rates in patients with hepatocellular carcinoma. Hepatology (2013) 1.74
T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase. J Clin Invest (2002) 1.74
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circ Res (2013) 1.72
Sustained normalization of high blood pressure in spontaneously hypertensive rats by implanted hemin pump. Hypertension (2006) 1.71
CXCR5+ CD4+ T follicular helper cells participate in the pathogenesis of primary biliary cirrhosis. Hepatology (2015) 1.70
TRPM7-mediated Ca2+ signals confer fibrogenesis in human atrial fibrillation. Circ Res (2010) 1.65
Calcium signaling in systemic lupus erythematosus T cells: a treatment target. Arthritis Rheum (2011) 1.65
Pro-apoptotic effect of endogenous H2S on human aorta smooth muscle cells. FASEB J (2006) 1.62
A new insight into Cannabis sativa (Cannabaceae) utilization from 2500-year-old Yanghai Tombs, Xinjiang, China. J Ethnopharmacol (2006) 1.61
Predicting catastrophes in nonlinear dynamical systems by compressive sensing. Phys Rev Lett (2011) 1.61
Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms. J Physiol (2005) 1.59
Knee articular cartilage damage in osteoarthritis: analysis of MR image biomarker reproducibility in ACRIN-PA 4001 multicenter trial. Radiology (2011) 1.58
Bmi-1 is related to proliferation, survival and poor prognosis in pancreatic cancer. Cancer Sci (2010) 1.58
H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells. J Biol Chem (2007) 1.56
Activity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentration. Proc Natl Acad Sci U S A (2002) 1.56
Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1. J Biol Chem (2004) 1.56
Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6-lpr/lpr mice. J Immunol (2010) 1.54
Spontaneous breathing with biphasic positive airway pressure attenuates lung injury in hydrochloric acid-induced acute respiratory distress syndrome. Anesthesiology (2014) 1.53
TNF signaling drives myeloid-derived suppressor cell accumulation. J Clin Invest (2012) 1.52
Graphene-on-silicon Schottky junction solar cells. Adv Mater (2010) 1.51
Pegylated interferon alpha therapy in acute hepatitis C: relation to hepatitis C virus-specific T cell response kinetics. Hepatology (2004) 1.51
Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production. Proc Natl Acad Sci U S A (2012) 1.49
Differentiation and hematopoietic-support of clonal cells in myelodysplastic syndromes. Leuk Lymphoma (2007) 1.49
The discovery of Capparis spinosa L. (Capparidaceae) in the Yanghai Tombs (2800 years b.p.), NW China, and its medicinal implications. J Ethnopharmacol (2007) 1.49
A novel prostate cancer susceptibility locus at 19q13. Cancer Res (2009) 1.49
Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells. PLoS One (2010) 1.48
Expression of LDL receptor-related protein 5 (LRP5) as a novel marker for disease progression in high-grade osteosarcoma. Int J Cancer (2004) 1.48
Zwitterionic polymers exhibiting high resistance to nonspecific protein adsorption from human serum and plasma. Biomacromolecules (2008) 1.48
Digital gene expression analysis based on integrated de novo transcriptome assembly of sweet potato [Ipomoea batatas (L.) Lam]. PLoS One (2012) 1.47
Tartary buckwheat (Fagopyrum tataricum Gaertn.) as a source of dietary rutin and quercitrin. J Agric Food Chem (2003) 1.46
Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas. Cancer Res (2012) 1.46
Increased expression of calcium-sensing receptors induced by ox-LDL amplifies apoptosis of cardiomyocytes during simulated ischaemia-reperfusion. Clin Exp Pharmacol Physiol (2010) 1.45
HAb18G (CD147), a cancer-associated biomarker and its role in cancer detection. Histopathology (2009) 1.45
Inhibition of autophagy ameliorates acute lung injury caused by avian influenza A H5N1 infection. Sci Signal (2012) 1.45
Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site. Mol Cell Biol (2010) 1.43
A half-log increase in BCR-ABL RNA predicts a higher risk of relapse in patients with chronic myeloid leukemia with an imatinib-induced complete cytogenetic response. Clin Cancer Res (2007) 1.41
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas. Oncotarget (2014) 1.40
Sequence and annotation of the 369-kb NY-2A and the 345-kb AR158 viruses that infect Chlorella NC64A. Virology (2006) 1.40
MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circ Res (2013) 1.39
Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion. J Biol Chem (2008) 1.38
Inhibition of bacterial adhesion and biofilm formation on zwitterionic surfaces. Biomaterials (2007) 1.38
Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk. Carcinogenesis (2011) 1.37
Cutting edge: Compartmentalization of Th1-like noninvariant CD1d-reactive T cells in hepatitis C virus-infected liver. J Immunol (2002) 1.37
Direct stimulation of K(ATP) channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells. Mol Pharmacol (2005) 1.35
B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B. J Immunol (2007) 1.35
microRNA expression profiling of nasopharyngeal carcinoma. Oncol Rep (2011) 1.34
Interaction of hydrogen sulfide with ion channels. Clin Exp Pharmacol Physiol (2010) 1.34
Overexpression of long non-coding RNA MALAT1 is correlated with clinical progression and unfavorable prognosis in pancreatic cancer. Tumour Biol (2014) 1.33
Effects of hydrogen sulfide on homocysteine-induced oxidative stress in vascular smooth muscle cells. Biochem Biophys Res Commun (2006) 1.31
Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose. Br J Pharmacol (2010) 1.31
Speckle tracking echocardiography in the assessment of mouse models of cardiac dysfunction. Am J Physiol Heart Circ Physiol (2009) 1.31
Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells. Cardiovasc Res (2010) 1.31
Phytochemical and genetic analyses of ancient cannabis from Central Asia. J Exp Bot (2008) 1.31
Predicting progression of IgA nephropathy: new clinical progression risk score. PLoS One (2012) 1.30
Progression of fibrosis in hepatitis C with and without schistosomiasis: correlation with serum markers of fibrosis. Hepatology (2006) 1.30
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients. Clin Immunol (2008) 1.30
Molecular mechanism for H(2)S-induced activation of K(ATP) channels. Antioxid Redox Signal (2010) 1.28
Hepatic CD1d expression in hepatitis C virus infection and recognition by resident proinflammatory CD1d-reactive T cells. J Immunol (2004) 1.27
Luteolin limits infarct size and improves cardiac function after myocardium ischemia/reperfusion injury in diabetic rats. PLoS One (2012) 1.27
Parallel mechanisms encode direction in the retina. Neuron (2011) 1.26
Video-assisted thoracoscopic surgery is more favorable than thoracotomy for administration of adjuvant chemotherapy after lobectomy for non-small cell lung cancer. World J Surg Oncol (2011) 1.26
Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Dev Biol (2007) 1.26
The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice. J Cancer Res Clin Oncol (2009) 1.26
Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis. Circulation (2013) 1.26
Asthmatic symptoms among pupils in relation to winter indoor and outdoor air pollution in schools in Taiyuan, China. Environ Health Perspect (2008) 1.25
Cellular immune responses in seronegative sexual contacts of acute hepatitis C patients. J Virol (2004) 1.25
Genetic markers associated with early cancer-specific mortality following prostatectomy. Cancer (2013) 1.25