Varenicline versus transdermal nicotine patch for smoking cessation: results from a randomised open-label trial.

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Published in Thorax on February 08, 2008

Authors

H-J Aubin1, A Bobak, J R Britton, C Oncken, C B Billing, J Gong, K E Williams, K R Reeves

Author Affiliations

1: Hôpital Emile Roux, Assistance Publique-Hopitaux de Paris, Limeil-Brévannes, Paris, France. henri-jean.aubin@erx.aphp.fr

Associated clinical trials:

Smoking Cessation in Subjects With Mild-to-moderate Chronic Obstructive Pulmonary Disease (COPD). | NCT00285012

Efficacy and Safety of Varenicline in Smokers With Cardiovascular Disease Who Wish to Quit Smoking | NCT00282984

An Open Label Study That Compares Varenicline to Transdermal Nicotine Patch for Smoking Cessation | NCT00143325

Reducing Cardiovascular Disease by Combining Smoking Cessation Pharmacotherapy and Behavioural Counseling (RW) | NCT01623505

Varenicline Versus Transdermal Nicotine Patch for Smoking Cessation in Patients With Coronary Heart Disease | NCT00959972

Human Laboratory Study Of Varenicline in Smokers | NCT00709696

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Descriptive epidemiology of bronchial reactivity in an adult population: results from a community study. Thorax (1987) 3.06

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T-cell cytokine responses in human infection with Mycobacterium tuberculosis. Infect Immun (1995) 2.57

The p53/p63/p73 family of transcription factors: overlapping and distinct functions. J Cell Sci (2000) 2.55

Bronchodilator, cardiovascular, and hypokalaemic effects of fenoterol, salbutamol, and terbutaline in asthma. Lancet (1990) 2.52

T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection. J Clin Invest (1994) 2.51

The effect of chemical treatments of albumin and orosomucoid on rate of clearance from the rat bloodstream and rate of pinocytic capture of rat yolk sac cultured in vitro. Biochem J (1977) 2.36

Phylogenetic analysis of rumen bacteria by comparative sequence analysis of cloned 16S rRNA genes. Anaerobe (1998) 2.31

Enhanced capacity of a widespread strain of Mycobacterium tuberculosis to grow in human macrophages. J Infect Dis (1999) 2.29

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Quantitative studies of pinocytosis. II. Kinetics of protein uptake and digestion by rat yolk sac cultured in vitro. J Cell Biol (1975) 2.20

Digestion of an exogenous protein by rat yolk-sac cultured in vitro. Biochem J (1971) 2.07

Assays of cell viability: discrimination of cells dying by apoptosis. Methods Cell Biol (1994) 2.06

What symptoms predict the bronchial response to histamine? Evaluation in a community survey of the bronchial symptoms questionnaire (1984) of the International Union Against Tuberculosis and Lung Disease. Int J Epidemiol (1989) 2.05

Response to inhaled histamine and 24 hour sodium excretion. Br Med J (Clin Res Ed) (1986) 2.01

Interleukin 12 at the site of disease in tuberculosis. J Clin Invest (1994) 1.98

The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res (1993) 1.88

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Estimation and repeatability of the response to inhaled histamine in a community survey. Thorax (1987) 1.85

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Expression profiling suggested a regulatory role of liver-enriched transcription factors in human hepatocellular carcinoma. Cancer Res (2001) 1.78

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Permeability lesions in male Escherichia coli infected with bacteriophage T7. Proc Natl Acad Sci U S A (1975) 1.71

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The distribution of peak expiratory flow variability in a population sample. Am Rev Respir Dis (1989) 1.66

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The role of white cells in the transmission of Yersinia enterocolitica in blood components. Transfusion (1992) 1.48

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Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes. Cytometry (1994) 1.45

The pinocytosis of 125I-labelled poly(vinylpyrrolidone), [14C]sucrose and colloidal [198Au]gold by rat yolk sac cultured in vitro. Biochem J (1977) 1.43

Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1. Oncogene (2007) 1.40

Host Status of Different Bermudagrasses (Cynodon spp.) for the Sting Nematode, Belonolaimus longicaudatus. J Nematol (1992) 1.40

Inter-observer variation in the histopathological reporting of Hodgkin's disease: an analysis of diagnostic subcomponents using kappa statistics. Histopathology (1983) 1.40

Cytometry of cyclin proteins. Cytometry (1996) 1.40

Effects of weak bases on the degradation of endogenous and exogenous proteins by rat yolk sacs. Biochem J (1980) 1.40

Use of extinction and reinforcement to increase food consumption and reduce expulsion. J Appl Behav Anal (1997) 1.39

Membrane microparticles mediate transfer of P-glycoprotein to drug sensitive cancer cells. Leukemia (2009) 1.37

Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress. J Biol Chem (1997) 1.36

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Bacterial meningitis in Navojo Indians. Public Health Rep (1976) 1.23

Prevalence of dementia and depression among elderly people in black and ethnic minorities. Br J Psychiatry (1997) 1.22

A quantitative study of pinocytosis and lysosome function in experimentally induced lysosomal storage. Biochem J (1976) 1.21

Concordance between p53 protein overexpression and gene mutation in a large series of common human carcinomas. Hum Pathol (1996) 1.20

Antimicrobial activity of essential oils and structurally related synthetic food additives towards selected pathogenic and beneficial gut bacteria. J Appl Microbiol (2006) 1.19

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Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis. Mech Ageing Dev (2000) 1.14

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Structure, function and regulation of p63 and p73. Cell Death Differ (1999) 1.12

Intramuscular (IM) ziprasidone 20 mg is effective in reducing acute agitation associated with psychosis: a double-blind, randomized trial. Psychopharmacology (Berl) (2001) 1.11

Effects of spectral smearing on phoneme and word recognition. J Acoust Soc Am (1996) 1.10

Liver disease in neonatal lupus erythematosus. J Pediatr (1990) 1.10

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Use of texture fading in the treatment of food selectivity. J Appl Behav Anal (1998) 1.06

Contextual effects of transforming growth factor beta on the tumorigenicity of human colon carcinoma cells. Cancer Res (1999) 1.06

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16S rDNA analysis of Butyrivibrio fibrisolvens: phylogenetic position and relation to butyrate-producing anaerobic bacteria from the rumen of white-tailed deer. Lett Appl Microbiol (1996) 1.05

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The use of pharmacotherapies for smoking cessation during pregnancy. Tob Control (2000) 1.03

Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system. Brain Res Brain Res Rev (1998) 1.02

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White cells protect donor blood against bacterial contamination. Transfusion (1991) 1.01

Relation of pulmonary lymphangio-leiomyomatosis to use of the oral contraceptive pill and fertility in the UK: a national case control study. Thorax (1994) 1.01

Breast cancer-associated antigen, DF3/MUC1, induces apoptosis of activated human T cells. Nat Med (1996) 1.01

Specific thromboxane synthetase inhibition and albumin excretion rate in insulin-dependent diabetes. Lancet (1984) 1.00

Personal Social Capital Scale: an instrument for health and behavioral research. Health Educ Res (2008) 1.00

Synovial accumulation of technetium labelled liposomes in rheumatoid arthritis. Ann Rheum Dis (1987) 0.98