Published in Traffic on February 11, 2008
Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum. Nat Immunol (2008) 2.45
Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites. Elife (2015) 1.36
Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth. J Biol Chem (2008) 1.34
Toxoplasma gondii prevents chromatin remodeling initiated by TLR-triggered macrophage activation. J Immunol (2009) 1.22
HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus. PLoS Pathog (2011) 1.16
Dysregulation of macrophage signal transduction by Toxoplasma gondii: past progress and recent advances. Parasite Immunol (2009) 1.07
Toxoplasma gondii actively inhibits neuronal function in chronically infected mice. PLoS One (2012) 1.04
Expression analysis of the Theileria parva subtelomere-encoded variable secreted protein gene family. PLoS One (2009) 0.99
Processing and secretion of ROP13: A unique Toxoplasma effector protein. Int J Parasitol (2010) 0.98
A HT/PEXEL motif in Toxoplasma dense granule proteins is a signal for protein cleavage but not export into the host cell. Traffic (2013) 0.94
Evaluation of Toxoplasma gondii as a live vaccine vector in susceptible and resistant hosts. Parasit Vectors (2011) 0.92
Toxoplasma-induced autophagy: a window into nutritional futile cycles in mammalian cells? Autophagy (2009) 0.81
Intracellular parasitism with Toxoplasma gondii stimulates mammalian-target-of-rapamycin-dependent host cell growth despite impaired signalling to S6K1 and 4E-BP1. Cell Microbiol (2009) 0.81
Dynamic development of parasitophorous vacuole of Eimeria tenella transfected with the yellow fluorescent protein gene fused to different signal sequences from apicomplexan parasites. Parasitol Res (2008) 0.80
Identification of Leishmania proteins preferentially released in infected cells using change mediated antigen technology (CMAT). PLoS Negl Trop Dis (2010) 0.79
Secretion of Antonospora (Paranosema) locustae proteins into infected cells suggests an active role of microsporidia in the control of host programs and metabolic processes. PLoS One (2014) 0.78
Identification and expression of Babesia ovis secreted antigen 1 and evaluation of its diagnostic potential in an enzyme-linked immunosorbent assay. J Clin Microbiol (2015) 0.78
Toxoplasma gondii ROP18: potential to manipulate host cell mitochondrial apoptosis. Parasitol Res (2016) 0.76
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J Biol Chem (2005) 3.87
Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay. Nat Biotechnol (2005) 2.92
Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles. PLoS Pathog (2005) 2.92
Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors. Proc Natl Acad Sci U S A (2007) 2.84
Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space. Cell (2006) 2.79
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Res (2005) 2.64
Pulling together: an integrated model of Toxoplasma cell invasion. Curr Opin Microbiol (2006) 2.37
Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host. Trends Parasitol (2005) 2.37
The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries. Cell Host Microbe (2011) 2.25
Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains. Infect Immun (2005) 2.21
Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells. Science (2008) 2.15
Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence. Proc Natl Acad Sci U S A (2011) 2.13
A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins. PLoS Biol (2012) 2.08
Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells. Eukaryot Cell (2006) 1.97
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii. Proc Natl Acad Sci U S A (2006) 1.95
Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion. Proc Natl Acad Sci U S A (2011) 1.94
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole. Cell Microbiol (2010) 1.94
Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6. J Biol Chem (2010) 1.87
Toxoplasma gondii asexual development: identification of developmentally regulated genes and distinct patterns of gene expression. Eukaryot Cell (2002) 1.81
Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription. J Biol Chem (2001) 1.78
Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii. Eukaryot Cell (2006) 1.64
Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation. Cell Host Microbe (2011) 1.62
Genetic analysis of tachyzoite to bradyzoite differentiation mutants in Toxoplasma gondii reveals a hierarchy of gene induction. Mol Microbiol (2002) 1.61
Bradyzoite-specific surface antigen SRS9 plays a role in maintaining Toxoplasma gondii persistence in the brain and in host control of parasite replication in the intestine. Infect Immun (2007) 1.55
Serotyping of Toxoplasma gondii infections in humans using synthetic peptides. J Infect Dis (2003) 1.53
A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole. Traffic (2009) 1.46
Toxoplasma gondii dysregulates IFN-gamma-inducible gene expression in human fibroblasts: insights from a genome-wide transcriptional profiling. J Immunol (2007) 1.44
Structure of the immunodominant surface antigen from the Toxoplasma gondii SRS superfamily. Nat Struct Biol (2002) 1.37
Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence. J Immunol (2005) 1.35
The C-terminus of Toxoplasma RON2 provides the crucial link between AMA1 and the host-associated invasion complex. PLoS Pathog (2011) 1.34
Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation. J Cell Biol (2004) 1.34
The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4. Infect Immun (2008) 1.31
Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PLoS One (2012) 1.27
A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence. Infect Immun (2008) 1.22
Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice. Exp Parasitol (2007) 1.22
Toxoplasma gondii infection specifically increases the levels of key host microRNAs. PLoS One (2010) 1.22
Toxoplasma co-opts host cells it does not invade. PLoS Pathog (2012) 1.21
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions. Nat Methods (2010) 1.20
Tissue barriers of the human placenta to infection with Toxoplasma gondii. Infect Immun (2011) 1.17
Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS One (2012) 1.15
NLRP1 is an inflammasome sensor for Toxoplasma gondii. Infect Immun (2013) 1.13
Role of calcium during Toxoplasma gondii invasion and egress. Int J Parasitol (2004) 1.12
Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication. Trends Parasitol (2011) 1.12
A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence. J Biol Chem (2011) 1.11
A highly sensitive FRET-based approach reveals secretion of the actin-binding protein toxofilin during Toxoplasma gondii infection. Cell Microbiol (2009) 1.10
The induction of acute ileitis by a single microbial antigen of Toxoplasma gondii. J Immunol (2004) 1.10
Identification and disruption of a rhoptry-localized homologue of sodium hydrogen exchangers in Toxoplasma gondii. Int J Parasitol (2005) 1.10
Unprocessed Toxoplasma ROP1 is effectively targeted and secreted into the nascent parasitophorous vacuole. Mol Biochem Parasitol (2002) 1.09
RNA analysis by biosynthetic tagging using 4-thiouracil and uracil phosphoribosyltransferase. Methods Mol Biol (2008) 1.09
Identification of tissue cyst wall components by transcriptome analysis of in vivo and in vitro Toxoplasma gondii bradyzoites. Eukaryot Cell (2011) 1.07
Expression quantitative trait locus mapping of toxoplasma genes reveals multiple mechanisms for strain-specific differences in gene expression. Eukaryot Cell (2008) 0.98
A novel rhoptry protein in Toxoplasma gondii bradyzoites and merozoites. Mol Biochem Parasitol (2005) 0.98
A nucleotide sugar transporter involved in glycosylation of the Toxoplasma tissue cyst wall is required for efficient persistence of bradyzoites. PLoS Pathog (2013) 0.96
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion. Proc Natl Acad Sci U S A (2011) 0.95
Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun (2011) 0.95
Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts. PLoS One (2011) 0.95
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion. Nat Chem Biol (2013) 0.93
A GFP-based motif-trap reveals a novel mechanism of targeting for the Toxoplasma ROP4 protein. Mol Biochem Parasitol (2004) 0.92
Infected dendritic cells facilitate systemic dissemination and transplacental passage of the obligate intracellular parasite Neospora caninum in mice. PLoS One (2012) 0.91
4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion. PLoS One (2009) 0.91
Analysis of gene expression during development: lessons from the Apicomplexa. Microbes Infect (2006) 0.91
Association of host mitochondria with the parasitophorous vacuole during Toxoplasma infection is not dependent on rhoptry proteins ROP2/8. Int J Parasitol (2010) 0.89
Disruption of a locus encoding a nucleolar zinc finger protein decreases tachyzoite-to-bradyzoite differentiation in Toxoplasma gondii. Infect Immun (2005) 0.88
Toxoplasma gondii sporozoites invade host cells using two novel paralogues of RON2 and AMA1. PLoS One (2013) 0.88
GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response. Infect Immun (2014) 0.87
A pseudouridine synthase homologue is critical to cellular differentiation in Toxoplasma gondii. Eukaryot Cell (2009) 0.87
The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognised by the P36 monoclonal antibody is SRS9. Int J Parasitol (2007) 0.87
Evidence for host cells as the major contributor of lipids in the intravacuolar network of Toxoplasma-infected cells. Eukaryot Cell (2011) 0.87
Use of two novel approaches to discriminate between closely related host microRNAs that are manipulated by Toxoplasma gondii during infection. RNA (2010) 0.85
Chemistry and biology of macrolide antiparasitic agents. J Med Chem (2011) 0.85
Infection by Toxoplasma gondii specifically induces host c-Myc and the genes this pivotal transcription factor regulates. Eukaryot Cell (2014) 0.84
Bradyzoite pseudokinase 1 is crucial for efficient oral infectivity of the Toxoplasma gondii tissue cyst. Eukaryot Cell (2013) 0.81