Published in Microbes Infect on January 25, 2006
The transcription of bradyzoite genes in Toxoplasma gondii is controlled by autonomous promoter elements. Mol Microbiol (2008) 1.50
The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation. Genome Biol (2008) 1.35
Toxoplasma: the next 100years. Microbes Infect (2008) 1.12
Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica. BMC Genomics (2007) 1.09
Comparative genomics of the Rab protein family in Apicomplexan parasites. Microbes Infect (2008) 1.06
A decade of epigenetic research in Toxoplasma gondii. Mol Biochem Parasitol (2010) 0.99
Understanding mechanisms and the role of differentiation in pathogenesis of Toxoplasma gondii: a review. Mem Inst Oswaldo Cruz (2009) 0.94
A developmentally regulated Myb domain protein regulates expression of a subset of stage-specific genes in Entamoeba histolytica. Cell Microbiol (2009) 0.90
Toxoplasma histone acetylation remodelers as novel drug targets. Expert Rev Anti Infect Ther (2012) 0.88
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J Biol Chem (2005) 3.87
Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay. Nat Biotechnol (2005) 2.92
Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles. PLoS Pathog (2005) 2.92
Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein. J Exp Med (2011) 2.87
Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors. Proc Natl Acad Sci U S A (2007) 2.84
Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space. Cell (2006) 2.79
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Res (2005) 2.64
Pulling together: an integrated model of Toxoplasma cell invasion. Curr Opin Microbiol (2006) 2.37
Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host. Trends Parasitol (2005) 2.37
The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries. Cell Host Microbe (2011) 2.25
Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains. Infect Immun (2005) 2.21
Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells. Science (2008) 2.15
Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence. Proc Natl Acad Sci U S A (2011) 2.13
A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins. PLoS Biol (2012) 2.08
Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells. Eukaryot Cell (2006) 1.97
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii. Proc Natl Acad Sci U S A (2006) 1.95
Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion. Proc Natl Acad Sci U S A (2011) 1.94
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole. Cell Microbiol (2010) 1.94
TU-tagging: cell type-specific RNA isolation from intact complex tissues. Nat Methods (2009) 1.90
Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6. J Biol Chem (2010) 1.87
Toxoplasma gondii asexual development: identification of developmentally regulated genes and distinct patterns of gene expression. Eukaryot Cell (2002) 1.81
Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription. J Biol Chem (2001) 1.78
Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii. Eukaryot Cell (2006) 1.64
Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation. Cell Host Microbe (2011) 1.62
Genetic analysis of tachyzoite to bradyzoite differentiation mutants in Toxoplasma gondii reveals a hierarchy of gene induction. Mol Microbiol (2002) 1.61
Bradyzoite-specific surface antigen SRS9 plays a role in maintaining Toxoplasma gondii persistence in the brain and in host control of parasite replication in the intestine. Infect Immun (2007) 1.55
Toxoplasma gondii effectors are master regulators of the inflammatory response. Trends Parasitol (2011) 1.53
Serotyping of Toxoplasma gondii infections in humans using synthetic peptides. J Infect Dis (2003) 1.53
A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole. Traffic (2009) 1.46
Toxoplasma gondii dysregulates IFN-gamma-inducible gene expression in human fibroblasts: insights from a genome-wide transcriptional profiling. J Immunol (2007) 1.44
The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response. PLoS Pathog (2012) 1.41
Structure of the immunodominant surface antigen from the Toxoplasma gondii SRS superfamily. Nat Struct Biol (2002) 1.37
Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence. J Immunol (2005) 1.35
The C-terminus of Toxoplasma RON2 provides the crucial link between AMA1 and the host-associated invasion complex. PLoS Pathog (2011) 1.34
Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation. J Cell Biol (2004) 1.34
The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4. Infect Immun (2008) 1.31
Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PLoS One (2012) 1.27
Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA. Genes Dev (2013) 1.24
Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice. Exp Parasitol (2007) 1.22
A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence. Infect Immun (2008) 1.22
Toxoplasma gondii infection specifically increases the levels of key host microRNAs. PLoS One (2010) 1.22
Toxoplasma co-opts host cells it does not invade. PLoS Pathog (2012) 1.21
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions. Nat Methods (2010) 1.20
Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it. PLoS One (2011) 1.17
Tissue barriers of the human placenta to infection with Toxoplasma gondii. Infect Immun (2011) 1.17
Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity. Proc Natl Acad Sci U S A (2012) 1.15
Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS One (2012) 1.15
NLRP1 is an inflammasome sensor for Toxoplasma gondii. Infect Immun (2013) 1.13
Role of calcium during Toxoplasma gondii invasion and egress. Int J Parasitol (2004) 1.12
Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication. Trends Parasitol (2011) 1.12
A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence. J Biol Chem (2011) 1.11
A highly sensitive FRET-based approach reveals secretion of the actin-binding protein toxofilin during Toxoplasma gondii infection. Cell Microbiol (2009) 1.10
The induction of acute ileitis by a single microbial antigen of Toxoplasma gondii. J Immunol (2004) 1.10
Identification and disruption of a rhoptry-localized homologue of sodium hydrogen exchangers in Toxoplasma gondii. Int J Parasitol (2005) 1.10
Secretion of proteins into host cells by Apicomplexan parasites. Traffic (2008) 1.10
Unprocessed Toxoplasma ROP1 is effectively targeted and secreted into the nascent parasitophorous vacuole. Mol Biochem Parasitol (2002) 1.09
RNA analysis by biosynthetic tagging using 4-thiouracil and uracil phosphoribosyltransferase. Methods Mol Biol (2008) 1.09
Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii. MBio (2014) 1.09
Identification of tissue cyst wall components by transcriptome analysis of in vivo and in vitro Toxoplasma gondii bradyzoites. Eukaryot Cell (2011) 1.07
Expression quantitative trait locus mapping of toxoplasma genes reveals multiple mechanisms for strain-specific differences in gene expression. Eukaryot Cell (2008) 0.98
Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15. Infect Immun (2013) 0.98
A novel rhoptry protein in Toxoplasma gondii bradyzoites and merozoites. Mol Biochem Parasitol (2005) 0.98
A nucleotide sugar transporter involved in glycosylation of the Toxoplasma tissue cyst wall is required for efficient persistence of bradyzoites. PLoS Pathog (2013) 0.96
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion. Proc Natl Acad Sci U S A (2011) 0.95
Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun (2011) 0.95
Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts. PLoS One (2011) 0.95
Toxoplasma gondii clonal strains all inhibit STAT1 transcriptional activity but polymorphic effectors differentially modulate IFNγ induced gene expression and STAT1 phosphorylation. PLoS One (2012) 0.94
De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs. BMC Genomics (2012) 0.94
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion. Nat Chem Biol (2013) 0.93
A GFP-based motif-trap reveals a novel mechanism of targeting for the Toxoplasma ROP4 protein. Mol Biochem Parasitol (2004) 0.92
4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion. PLoS One (2009) 0.91
Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling. Int J Parasitol (2011) 0.91
Infected dendritic cells facilitate systemic dissemination and transplacental passage of the obligate intracellular parasite Neospora caninum in mice. PLoS One (2012) 0.91
Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication. Infect Immun (2013) 0.89
Ontogeny of the common carp (Cyprinus carpio L.) innate immune system. Dev Comp Immunol (2005) 0.89
Association of host mitochondria with the parasitophorous vacuole during Toxoplasma infection is not dependent on rhoptry proteins ROP2/8. Int J Parasitol (2010) 0.89
Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains. BMC Genomics (2013) 0.88
Toxoplasma gondii sporozoites invade host cells using two novel paralogues of RON2 and AMA1. PLoS One (2013) 0.88
Disruption of a locus encoding a nucleolar zinc finger protein decreases tachyzoite-to-bradyzoite differentiation in Toxoplasma gondii. Infect Immun (2005) 0.88
Toxoplasma gondii Inhibits gamma interferon (IFN-γ)- and IFN-β-induced host cell STAT1 transcriptional activity by increasing the association of STAT1 with DNA. Infect Immun (2013) 0.87
Evidence for host cells as the major contributor of lipids in the intravacuolar network of Toxoplasma-infected cells. Eukaryot Cell (2011) 0.87
A pseudouridine synthase homologue is critical to cellular differentiation in Toxoplasma gondii. Eukaryot Cell (2009) 0.87
Cactin is essential for G1 progression in Toxoplasma gondii. Mol Microbiol (2012) 0.87
GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response. Infect Immun (2014) 0.87
The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognised by the P36 monoclonal antibody is SRS9. Int J Parasitol (2007) 0.87
Structure of the Toxoplasma gondii ROP18 kinase domain reveals a second ligand binding pocket required for acute virulence. J Biol Chem (2013) 0.87
The genetic basis for individual differences in mRNA splicing and APOBEC1 editing activity in murine macrophages. Genome Res (2013) 0.86
Use of two novel approaches to discriminate between closely related host microRNAs that are manipulated by Toxoplasma gondii during infection. RNA (2010) 0.85
Chemistry and biology of macrolide antiparasitic agents. J Med Chem (2011) 0.85
Infection by Toxoplasma gondii specifically induces host c-Myc and the genes this pivotal transcription factor regulates. Eukaryot Cell (2014) 0.84
Drosophila Polycomb complexes restrict neuroblast competence to generate motoneurons. Development (2012) 0.82
Bradyzoite pseudokinase 1 is crucial for efficient oral infectivity of the Toxoplasma gondii tissue cyst. Eukaryot Cell (2013) 0.81
The Drosophila SERTAD protein Taranis determines lineage-specific neural progenitor proliferation patterns. Dev Biol (2013) 0.79