Published in Biochem Biophys Res Commun on February 11, 2008
Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma. Cancer Res (2010) 1.21
Transcriptional and epigenetic regulation of opioid receptor genes: present and future. Annu Rev Pharmacol Toxicol (2011) 0.97
Nerve growth factor-regulated emergence of functional delta-opioid receptors. J Neurosci (2010) 0.96
Crosstalk between delta opioid receptor and nerve growth factor signaling modulates neuroprotection and differentiation in rodent cell models. Int J Mol Sci (2013) 0.76
A PTEN-Regulated Checkpoint Controls Surface Delivery of δ Opioid Receptors. J Neurosci (2017) 0.75
Mu-opioid signaling modulates biphasic expression of TrkB and IκBα genes and neurite outgrowth in differentiating and differentiated human neuroblastoma cells. Biochem Biophys Res Commun (2013) 0.75
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A (1976) 21.06
The diverse functions of histone lysine methylation. Nat Rev Mol Cell Biol (2005) 12.70
Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem (2003) 8.83
The many faces of histone lysine methylation. Curr Opin Cell Biol (2002) 6.01
Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell (2005) 5.96
The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell (2002) 5.84
Apoptosis in the nervous system. Nature (2000) 5.82
Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. Mol Cell (2000) 5.79
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol (2001) 4.43
Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell (2000) 4.05
Nerve growth factor signaling, neuroprotection, and neural repair. Annu Rev Neurosci (2001) 3.53
Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation. EMBO J (2000) 3.35
Exploring the opioid system by gene knockout. Prog Neurobiol (2002) 2.69
Reversing histone methylation. Nature (2005) 2.57
Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes. Genes Dev (2002) 2.10
Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment. Proc Natl Acad Sci U S A (1995) 1.64
Role of delta-opioid receptor function in neurogenesis and neuroprotection. J Neurochem (2006) 1.23
Neuroprotective role of delta-opioid receptors in cortical neurons. Am J Physiol Cell Physiol (2002) 1.09
Developmental expression of the mu, kappa, and delta opioid receptor mRNAs in mouse. J Neurosci (1998) 1.06
Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells. J Biol Chem (2006) 0.99
Nerve growth factor receptor signaling induces histone acetyltransferase domain-dependent nuclear translocation of p300/CREB-binding protein-associated factor and hGCN5 acetyltransferases. J Biol Chem (2004) 0.97
Opioid receptor gene expression in the rat brain during ontogeny, with special reference to the mesostriatal system: an in situ hybridization study. Brain Res Dev Brain Res (1998) 0.90
DNA methylation-related chromatin modification in the regulation of mouse delta-opioid receptor gene. Mol Pharmacol (2005) 0.89
Reciprocal developmental changes in the roles of Bcl-w and Bcl-x(L) in regulating sensory neuron survival. Development (2001) 0.89
Genomic structure of the mouse delta opioid receptor gene. Biochem Biophys Res Commun (1995) 0.89
Deletion of delta-opioid receptor in mice alters skin differentiation and delays wound healing. Differentiation (2006) 0.88
Sustained activation of phosphatidylinositol 3-kinase/Akt/nuclear factor kappaB signaling mediates G protein-coupled delta-opioid receptor gene expression. J Biol Chem (2005) 0.86
Inhibition of akt/protein kinase B signaling by naltrindole in small cell lung cancer cells. Cancer Res (2004) 0.85
Action of NF-kappaB on the delta opioid receptor gene promoter. Biochem Biophys Res Commun (2006) 0.81
Characterization of a delta opioid receptor in rat pheochromocytoma cells. J Pharmacol Exp Ther (1995) 0.81
Nerve growth factor induces specific enkephalin binding sites in a nerve cell line. J Biol Chem (1982) 0.81
Opioids transiently prevent activation of apoptotic mechanisms following short periods of serum withdrawal. J Neurochem (2000) 0.80
The influence of different sub-type delta opioid receptors in nerve growth factor-induced neuronal differentiation in rat pheochromocytoma PC12 cell. Neurosci Lett (2001) 0.78
Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series. Proc Natl Acad Sci U S A (2005) 2.29
Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids. Cell (2011) 2.13
Beta-arrestin-dependent mu-opioid receptor-activated extracellular signal-regulated kinases (ERKs) Translocate to Nucleus in Contrast to G protein-dependent ERK activation. Mol Pharmacol (2007) 1.56
Agonist-selective signaling is determined by the receptor location within the membrane domains. Proc Natl Acad Sci U S A (2008) 1.36
Axonal mRNA transport and localized translational regulation of kappa-opioid receptor in primary neurons of dorsal root ganglia. Proc Natl Acad Sci U S A (2006) 1.35
Mu-opioid receptors modulate the stability of dendritic spines. Proc Natl Acad Sci U S A (2005) 1.34
Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions. J Biol Chem (2005) 1.34
Spinal G-protein-gated potassium channels contribute in a dose-dependent manner to the analgesic effect of mu- and delta- but not kappa-opioids. J Neurosci (2005) 1.33
Inhibition of PI3K/Akt signaling: an emerging paradigm for targeted cancer therapy. Curr Med Chem Anticancer Agents (2005) 1.32
Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. Mol Cell Biol (2007) 1.25
Mu-opioid receptor desensitization: role of receptor phosphorylation, internalization, and representation. J Biol Chem (2003) 1.25
Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor. J Cell Mol Med (2008) 1.21
Adenylyl cyclase superactivation induced by long-term treatment with opioid agonist is dependent on receptor localized within lipid rafts and is independent of receptor internalization. Mol Pharmacol (2006) 1.21
Poly(C)-binding proteins as transcriptional regulators of gene expression. Biochem Biophys Res Commun (2009) 1.20
Morphine-induced mu-opioid receptor rapid desensitization is independent of receptor phosphorylation and beta-arrestins. Cell Signal (2008) 1.19
mu-Opioid receptor agonists differentially regulate the expression of miR-190 and NeuroD. Mol Pharmacol (2009) 1.18
Morphine regulates dopaminergic neuron differentiation via miR-133b. Mol Pharmacol (2010) 1.18
Regulation of opioid receptor expression. Curr Opin Pharmacol (2002) 1.16
Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling. EMBO J (2009) 1.16
Agonist-selective signaling of G protein-coupled receptor: mechanisms and implications. IUBMB Life (2010) 1.14
Neuron-restrictive silencer factor (NRSF) functions as a repressor in neuronal cells to regulate the mu opioid receptor gene. J Biol Chem (2004) 1.13
Distinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptors. Mol Cell Neurosci (2007) 1.12
Rewarding effects of ethanol and cocaine in mu opioid receptor-deficient mice. Naunyn Schmiedebergs Arch Pharmacol (2002) 1.11
Yin Yang 1 phosphorylation contributes to the differential effects of mu-opioid receptor agonists on microRNA-190 expression. J Biol Chem (2010) 1.11
Poly(C) binding protein family is a transcription factor in mu-opioid receptor gene expression. Mol Pharmacol (2005) 1.11
Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling. BMC Cell Biol (2012) 1.10
Netrin-1 signaling regulates de novo protein synthesis of kappa opioid receptor by facilitating polysomal partition of its mRNA. J Neurosci (2006) 1.08
Post-transcriptional regulation of opioid receptors in the nervous system. Front Biosci (2004) 1.06
Mouse kappa-opioid receptor mRNA differential transport in neurons. Mol Pharmacol (2003) 1.05
Up-regulation of the mu-opioid receptor gene is mediated through chromatin remodeling and transcriptional factors in differentiated neuronal cells. Mol Pharmacol (2010) 1.04
Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene. Nucleic Acids Res (2006) 1.04
Long-term morphine treatment decreases the association of mu-opioid receptor (MOR1) mRNA with polysomes through miRNA23b. Mol Pharmacol (2009) 1.04
Copb1-facilitated axonal transport and translation of kappa opioid-receptor mRNA. Proc Natl Acad Sci U S A (2007) 1.03
Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene. FASEB J (2007) 1.03
Transcriptional regulation of mouse mu opioid receptor gene by PU.1. J Biol Chem (2004) 1.03
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization. Cell Signal (2010) 1.03
Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins. J Biol Chem (2002) 1.03
Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl on dendritic spine stability. J Neurosci (2010) 1.02
The immunosuppressive effects of chronic morphine treatment are partially dependent on corticosterone and mediated by the mu-opioid receptor. J Leukoc Biol (2002) 1.02
The opioid ligand binding of human mu-opioid receptor is modulated by novel splice variants of the receptor. Biochem Biophys Res Commun (2006) 1.02
Translational repression of mouse mu opioid receptor expression via leaky scanning. Nucleic Acids Res (2007) 1.00
Poly C binding protein, a single-stranded DNA binding protein, regulates mouse mu-opioid receptor gene expression. J Neurochem (2005) 1.00
Modulating micro-opioid receptor phosphorylation switches agonist-dependent signaling as reflected in PKCepsilon activation and dendritic spine stability. J Biol Chem (2011) 1.00
A proteomics approach for identification of single strand DNA-binding proteins involved in transcriptional regulation of mouse mu opioid receptor gene. Mol Cell Proteomics (2008) 0.99
Increased dopamine D2 receptor binding and enhanced apomorphine-induced locomotor activity in mu-opioid receptor knockout mice. Brain Res Bull (2003) 0.98
Post-transcriptional regulation of mouse mu opioid receptor (MOR1) via its 3' untranslated region: a role for microRNA23b. FASEB J (2008) 0.98
Transcriptional regulation of mouse mu opioid receptor gene: Sp3 isoforms (M1, M2) function as repressors in neuronal cells to regulate the mu opioid receptor gene. Mol Pharmacol (2005) 0.98
Transcriptional and epigenetic regulation of opioid receptor genes: present and future. Annu Rev Pharmacol Toxicol (2011) 0.97
Rescuing the traffic-deficient mutants of rat mu-opioid receptors with hydrophobic ligands. Mol Pharmacol (2003) 0.97
Src phosphorylation of micro-receptor is responsible for the receptor switching from an inhibitory to a stimulatory signal. J Biol Chem (2008) 0.97
MicroRNAs in opioid pharmacology. J Neuroimmune Pharmacol (2011) 0.96
Morphine negatively regulates interferon-gamma promoter activity in activated murine T cells through two distinct cyclic AMP-dependent pathways. J Biol Chem (2003) 0.95
Nuclear factor kappaB signaling in opioid functions and receptor gene expression. J Neuroimmune Pharmacol (2006) 0.95
mu-Opioid receptor knockout mice are insensitive to methamphetamine-induced behavioral sensitization. J Neurosci Res (2010) 0.95
Retinoic acid-induced chromatin remodeling of mouse kappa opioid receptor gene. J Neurosci (2005) 0.95
Phosphorylation of the delta-opioid receptor regulates its beta-arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization. J Biol Chem (2007) 0.94
Short- and long-term regulation of adenylyl cyclase activity by delta-opioid receptor are mediated by Galphai2 in neuroblastoma N2A cells. Mol Pharmacol (2006) 0.94
Molecular basis underlying the poly C binding protein 1 as a regulator of the proximal promoter of mouse mu-opioid receptor gene. Brain Res (2006) 0.93
Effects of trichostatin A on neuronal mu-opioid receptor gene expression. Brain Res (2008) 0.93
Geldanamycin inhibits hemorrhage-induced increases in caspase-3 activity: role of inducible nitric oxide synthase. J Appl Physiol (1985) (2007) 0.93
Chronic morphine treatment differentiates T helper cells to Th2 effector cells by modulating transcription factors GATA 3 and T-bet. J Neuroimmunol (2004) 0.92
Differential promoter usage of mouse mu-opioid receptor gene during development. Brain Res Mol Brain Res (2002) 0.92
The other side of the opioid story: modulation of cell growth and survival signaling. Curr Med Chem (2008) 0.92
MicroRNA 339 down-regulates μ-opioid receptor at the post-transcriptional level in response to opioid treatment. FASEB J (2012) 0.92
DPDPE-UK14,304 synergy is retained in mu opioid receptor knockout mice. Pain (2003) 0.91