Published in Mutat Res on January 03, 2008
Cocoa polyphenols and their potential benefits for human health. Oxid Med Cell Longev (2012) 0.94
Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson's disease. J Ethnopharmacol (2009) 0.91
Grape seed proanthocyanidin extract protects human lens epithelial cells from oxidative stress via reducing NF-кB and MAPK protein expression. Mol Vis (2011) 0.88
Composition, standardization and chemical profiling of Banisteriopsis caapi, a plant for the treatment of neurodegenerative disorders relevant to Parkinson's disease. J Ethnopharmacol (2010) 0.79
Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress. Eur J Nutr (2008) 0.79
Theobroma cacao: Review of the Extraction, Isolation, and Bioassay of Its Potential Anti-cancer Compounds. Trop Life Sci Res (2016) 0.75
Cocoa has more phenolic phytochemicals and a higher antioxidant capacity than teas and red wine. J Agric Food Chem (2003) 1.66
Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals. J Agric Food Chem (2002) 1.64
Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex. Mol Cell (2012) 1.50
Cocoa procyanidins inhibit expression and activation of MMP-2 in vascular smooth muscle cells by direct inhibition of MEK and MT1-MMP activities. Cardiovasc Res (2008) 1.44
Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine. Cancer Res (2008) 1.30
Structure of the stapled p53 peptide bound to Mdm2. J Am Chem Soc (2011) 1.30
Myricetin suppresses UVB-induced skin cancer by targeting Fyn. Cancer Res (2008) 1.29
Tpl2 is a key mediator of arsenite-induced signal transduction. Cancer Res (2009) 1.26
Naturally occurring phytochemicals for the prevention of Alzheimer's disease. J Neurochem (2009) 1.25
Molecular determinants of ovarian cancer chemoresistance: new insights into an old conundrum. Ann N Y Acad Sci (2012) 1.22
Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation. Cancer Res (2008) 1.20
Major phenolics in apple and their contribution to the total antioxidant capacity. J Agric Food Chem (2003) 1.19
Resveratrol directly targets COX-2 to inhibit carcinogenesis. Mol Carcinog (2008) 1.17
Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1. Carcinogenesis (2007) 1.11
Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells. Cardiovasc Res (2009) 1.10
The roles of polyphenols in cancer chemoprevention. Biofactors (2006) 1.07
Soy isoflavones and cognitive function. J Nutr Biochem (2005) 1.07
Luteolin inhibits protein kinase C(epsilon) and c-Src activities and UVB-induced skin cancer. Cancer Res (2010) 1.07
Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression. Carcinogenesis (2008) 1.07
USP8 is a novel target for overcoming gefitinib resistance in lung cancer. Clin Cancer Res (2013) 1.04
Kaempferol inhibits UVB-induced COX-2 expression by suppressing Src kinase activity. Biochem Pharmacol (2010) 1.03
Variation in major antioxidants and total antioxidant activity of Yuzu (Citrus junos Sieb ex Tanaka) during maturation and between cultivars. J Agric Food Chem (2004) 1.03
Vitamin C and cancer chemoprevention: reappraisal. Am J Clin Nutr (2003) 1.01
de Quervain disease: US identification of anatomic variations in the first extensor compartment with an emphasis on subcompartmentalization. Radiology (2011) 1.01
T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation. Cancer Res (2007) 1.00
Essential role of Cenexin1, but not Odf2, in ciliogenesis. Cell Cycle (2013) 0.99
Antiproliferative effects of dietary phenolic substances and hydrogen peroxide. J Agric Food Chem (2005) 0.98
Interpreting positive signs of the supraspinatus test in screening for torn rotator cuff. Acta Med Okayama (2006) 0.98
Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis. Pharmacol Ther (2011) 0.98
Biphasic effects of dietary antioxidants on oxidative stress-mediated carcinogenesis. Mech Ageing Dev (2006) 0.97
Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK. Carcinogenesis (2011) 0.97
Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice. Breast Cancer Res (2011) 0.96
Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase. Carcinogenesis (2009) 0.96
Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K. Cancer Prev Res (Phila) (2011) 0.96
Inhibitory effect of tumor cell proliferation and induction of G2/M cell cycle arrest by panaxytriol. Planta Med (2002) 0.96
Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation. J Biol Chem (2012) 0.94
Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells. Antioxid Redox Signal (2005) 0.94
Protective effect of quercetin against arsenite-induced COX-2 expression by targeting PI3K in rat liver epithelial cells. J Agric Food Chem (2010) 0.94
Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin. Int J Biochem Cell Biol (2009) 0.93
6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2. Carcinogenesis (2011) 0.93
Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells. Biopolymers (2014) 0.93
Src kinase is a direct target of apigenin against UVB-induced skin inflammation. Carcinogenesis (2012) 0.93
Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase. J Biol Chem (2008) 0.92
Overexpression of IL-32alpha increases natural killer cell-mediated killing through up-regulation of Fas and UL16-binding protein 2 (ULBP2) expression in human chronic myeloid leukemia cells. J Biol Chem (2011) 0.92
A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice. Mol Carcinog (2011) 0.92
H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kappaB: an implication for invasive phenotype in rat liver epithelial cells. Int J Cancer (2006) 0.92
Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway. J Biol Chem (2007) 0.91
Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission. J Biol Chem (2013) 0.91
Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells. Ann N Y Acad Sci (2007) 0.91
Esculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin. Cancer Prev Res (Phila) (2013) 0.90
7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4. J Biol Chem (2011) 0.90
Protective effects of piceatannol against beta-amyloid-induced neuronal cell death. Ann N Y Acad Sci (2007) 0.90
Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis. Ann N Y Acad Sci (2011) 0.89
Eupatilin, a major flavonoid of Artemisia, attenuates aortic smooth muscle cell proliferation and migration by inhibiting PI3K, MKK3/6, and MKK4 activities. Planta Med (2013) 0.89
High-fat diet-induced obesity increases lymphangiogenesis and lymph node metastasis in the B16F10 melanoma allograft model: roles of adipocytes and M2-macrophages. Int J Cancer (2014) 0.89
Soy isoflavones improve spatial delayed matching-to-place performance and reduce cholinergic neuron loss in elderly male rats. J Nutr (2004) 0.89
Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1. Cancer Res (2010) 0.89
Allyl isothiocyanate and its N-acetylcysteine conjugate suppress metastasis via inhibition of invasion, migration, and matrix metalloproteinase-2/-9 activities in SK-Hep 1 human hepatoma cells. Exp Biol Med (Maywood) (2006) 0.89
Antioxidant activity of black tea vs. green tea. J Nutr (2002) 0.89
Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1. Biochem Pharmacol (2010) 0.88
Jaceosidin, a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and -2 in cultured human mammary epithelial cells. Ann N Y Acad Sci (2007) 0.88
Caffeinated coffee, decaffeinated coffee, and the phenolic phytochemical chlorogenic acid up-regulate NQO1 expression and prevent H₂O₂-induced apoptosis in primary cortical neurons. Neurochem Int (2012) 0.88
Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester. Ann N Y Acad Sci (2004) 0.88
Inhibitory effects of lycopene on the adhesion, invasion, and migration of SK-Hep1 human hepatoma cells. Exp Biol Med (Maywood) (2006) 0.88
Phloretin induces apoptosis in H-Ras MCF10A human breast tumor cells through the activation of p53 via JNK and p38 mitogen-activated protein kinase signaling. Ann N Y Acad Sci (2009) 0.88
Preventive effects of vitamin C on carcinogenesis. Lancet (2002) 0.88
5-deoxykaempferol plays a potential therapeutic role by targeting multiple signaling pathways in skin cancer. Cancer Prev Res (Phila) (2010) 0.87