Published in Glia on April 15, 2008
Estrogen effects on the brain: actions beyond the hypothalamus via novel mechanisms. Behav Neurosci (2012) 1.31
Microglia express distinct M1 and M2 phenotypic markers in the postnatal and adult central nervous system in male and female mice. J Neurosci Res (2013) 1.28
Estrogen regulation of glucose metabolism and mitochondrial function: therapeutic implications for prevention of Alzheimer's disease. Adv Drug Deliv Rev (2008) 1.21
Rapid estrogen signaling in the brain: implications for the fine-tuning of neuronal circuitry. J Neurosci (2011) 1.17
Progesterone increases rat neural progenitor cell cycle gene expression and proliferation via extracellularly regulated kinase and progesterone receptor membrane components 1 and 2. Endocrinology (2009) 1.15
Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytes. Proc Natl Acad Sci U S A (2010) 1.09
Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism. Proc Natl Acad Sci U S A (2011) 1.07
Surveillance, phagocytosis, and inflammation: how never-resting microglia influence adult hippocampal neurogenesis. Neural Plast (2014) 1.07
A genome-wide signature of glucocorticoid receptor binding in neuronal PC12 cells. BMC Neurosci (2012) 1.04
Microglia across the lifespan: from origin to function in brain development, plasticity and cognition. J Physiol (2016) 1.02
The HPA - Immune Axis and the Immunomodulatory Actions of Glucocorticoids in the Brain. Front Immunol (2014) 1.02
Role of spinal cord glia in the central processing of peripheral pain perception. Neurogastroenterol Motil (2010) 1.01
Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration. Brain Res Bull (2014) 1.01
Distribution of angiotensin type 1a receptor-containing cells in the brains of bacterial artificial chromosome transgenic mice. Neuroscience (2012) 1.01
Insights into rapid modulation of neuroplasticity by brain estrogens. Pharmacol Rev (2013) 0.99
Distribution of phosphorylated TrkB receptor in the mouse hippocampal formation depends on sex and estrous cycle stage. J Neurosci (2011) 0.98
Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats. Psychoneuroendocrinology (2012) 0.97
Acute and chronic stress-induced disturbances of microglial plasticity, phenotype and function. Curr Drug Targets (2013) 0.97
Distribution of estrogen receptor β containing cells in the brains of bacterial artificial chromosome transgenic mice. Brain Res (2010) 0.95
GPR30, but not estrogen receptor-alpha, is crucial in the treatment of experimental autoimmune encephalomyelitis by oral ethinyl estradiol. BMC Immunol (2010) 0.95
Inflammation in Parkinson's disease: role of glucocorticoids. Front Neuroanat (2015) 0.95
Sex and hormonal influences on seizures and epilepsy. Horm Behav (2012) 0.95
Estrogen Effects on Cognitive and Synaptic Health Over the Lifecourse. Physiol Rev (2015) 0.95
Ultrastructural localization of extranuclear progestin receptors in the rat hippocampal formation. J Comp Neurol (2008) 0.94
Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation. Neurobiol Aging (2013) 0.93
Estrogens regulate neuroinflammatory genes via estrogen receptors α and β in the frontal cortex of middle-aged female rats. J Neuroinflammation (2011) 0.92
Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation. J Neurosci (2013) 0.89
Differential effects of homotypic vs. heterotypic chronic stress regimens on microglial activation in the prefrontal cortex. Physiol Behav (2013) 0.88
Differential effects of stress on microglial cell activation in male and female medial prefrontal cortex. Brain Behav Immun (2015) 0.87
Oligodendroglial alterations and the role of microglia in white matter injury: relevance to schizophrenia. Dev Neurosci (2013) 0.87
Estrogens, Neuroinflammation, and Neurodegeneration. Endocr Rev (2016) 0.87
Sex differences in neurodevelopmental and neurodegenerative disorders: Focus on microglial function and neuroinflammation during development. J Steroid Biochem Mol Biol (2015) 0.86
Progesterone influence on neurite outgrowth involves microglia. Endocrinology (2008) 0.86
The aldosterone-mineralocorticoid receptor pathway exerts anti-inflammatory effects in endotoxin-induced uveitis. PLoS One (2012) 0.85
Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness. Psychopharmacology (Berl) (2016) 0.84
Responses of glial cells to stress and glucocorticoids. Curr Immunol Rev (2010) 0.84
Intrathecal injection of spironolactone attenuates radicular pain by inhibition of spinal microglia activation in a rat model. PLoS One (2012) 0.82
Identifying the cellular targets of drug action in the central nervous system following corticosteroid therapy. ACS Chem Neurosci (2013) 0.82
Inhibition by female sex hormones of collagen degradation by corneal fibroblasts. Mol Vis (2011) 0.82
Progesterone antagonism of neurite outgrowth depends on microglial activation via Pgrmc1/S2R. Endocrinology (2013) 0.81
Potent and multiple regulatory actions of microglial glucocorticoid receptors during CNS inflammation. Cell Death Differ (2013) 0.80
Neuroprotective effects of estradiol on motoneurons in a model of rat spinal cord embryonic explants. Cell Mol Neurobiol (2013) 0.80
17α-estradiol attenuates neuron loss in ovariectomized Dtg AβPP/PS1 mice. J Alzheimers Dis (2011) 0.80
Estrogen and P2 Purinergic Receptor Systems in Microglia: Therapeutic Targets for Neuroprotection. Open Drug Discov J (2010) 0.80
Stroke neuroprotection: oestrogen and insulin-like growth factor-1 interactions and the role of microglia. J Neuroendocrinol (2013) 0.80
Progesterone and nestorone promote myelin regeneration in chronic demyelinating lesions of corpus callosum and cerebral cortex. Glia (2014) 0.80
Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia. Neurobiol Aging (2014) 0.80
Tissue expression of steroid hormone receptors is associated with differential immune responsiveness. Brain Behav Immun (2010) 0.79
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. J Neuroinflammation (2012) 0.79
Acute and chronic glucocorticoid treatments regulate astrocyte-enriched mRNAs in multiple brain regions in vivo. Front Neurosci (2013) 0.79
Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization. Transl Psychiatry (2017) 0.78
Ovariectomy and subsequent treatment with estrogen receptor agonists tune the innate immune system of the hippocampus in middle-aged female rats. PLoS One (2014) 0.78
Activation of glucocorticoid receptors in Müller glia is protective to retinal neurons and suppresses microglial reactivity. Exp Neurol (2015) 0.78
Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury. Front Aging Neurosci (2014) 0.78
17beta-estradiol counteracts neuropathic pain: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice. Sci Rep (2016) 0.78
A novel mouse model of Alzheimer's disease with chronic estrogen deficiency leads to glial cell activation and hypertrophy. J Aging Res (2011) 0.77
Role of Glia in Stress-Induced Enhancement and Impairment of Memory. Front Integr Neurosci (2016) 0.77
Missing and Possible Link between Neuroendocrine Factors, Neuropsychiatric Disorders, and Microglia. Front Integr Neurosci (2013) 0.77
The effects of cytosine methylation on general transcription factors. Sci Rep (2016) 0.77
Pgrmc1: new roles in the microglial mediation of progesterone-antagonism of estradiol-dependent neurite sprouting and in microglial activation. Front Neurosci (2013) 0.77
Estrogen receptor alpha deficiency protects against development of cognitive impairment in murine lupus. J Neuroinflammation (2014) 0.77
Intravitreous delivery of the corticosteroid fluocinolone acetonide attenuates retinal degeneration in S334ter-4 rats. Invest Ophthalmol Vis Sci (2010) 0.77
Microglia Ontology and Signaling. Front Cell Dev Biol (2016) 0.77
Astroglia-Microglia Cross Talk during Neurodegeneration in the Rat Hippocampus. Biomed Res Int (2015) 0.77
Microglial P2 Purinergic Receptor and Immunomodulatory Gene Transcripts Vary By Region, Sex, and Age in the Healthy Mouse CNS. Transcr Open Access (2015) 0.76
17beta-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss. Neurobiol Dis (2010) 0.76
The microbiome: A key regulator of stress and neuroinflammation. Neurobiol Stress (2016) 0.76
Estrogen ameliorates microglial activation by inhibiting the Kir2.1 inward-rectifier K(+) channel. Sci Rep (2016) 0.75
Sex differences in microglial colonization and vulnerabilities to endocrine disruption in the social brain. Gen Comp Endocrinol (2016) 0.75
Peripheral vs. Central Sex Steroid Hormones in Experimental Parkinson's Disease. Front Endocrinol (Lausanne) (2011) 0.75
Sex differences in innate immunity and its impact on opioid pharmacology. J Neurosci Res (2017) 0.75
Neuroprotection via Reduction in Stress: Altered Menstrual Patterns as a Marker for Stress and Implications for Long-Term Neurologic Health in Women. Int J Mol Sci (2016) 0.75
Microglial Function across the Spectrum of Age and Gender. Int J Mol Sci (2017) 0.75
Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors. Front Neuroendocrinol (2016) 0.75
The Effect of Glucocorticoid and Glucocorticoid Receptor Interactions on Brain, Spinal Cord, and Glial Cell Plasticity. Neural Plast (2017) 0.75
Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci (2009) 11.02
Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention. JAMA (2009) 7.90
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science (2006) 5.89
Allostatic load biomarkers of chronic stress and impact on health and cognition. Neurosci Biobehav Rev (2009) 5.40
Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry (2005) 4.81
Stress, memory and the amygdala. Nat Rev Neurosci (2009) 4.57
Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. J Neurosci (2006) 3.96
Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex. Cereb Cortex (2005) 3.71
Course of illness, hippocampal function, and hippocampal volume in major depression. Proc Natl Acad Sci U S A (2003) 3.29
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am J Pathol (2002) 3.23
Activation of p75NTR by proBDNF facilitates hippocampal long-term depression. Nat Neurosci (2005) 3.17
Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus. J Comp Neurol (2004) 3.12
The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease. Neurosci Biobehav Rev (2004) 3.10
Adverse childhood experiences, allostasis, allostatic load, and age-related disease. Physiol Behav (2011) 3.04
Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha. Endocrinology (2003) 2.85
The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission. Nat Rev Neurosci (2011) 2.82
Allostatic load as a predictor of functional decline. MacArthur studies of successful aging. J Clin Epidemiol (2002) 2.78
Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain. J Neurosci (2004) 2.64
Stress duration modulates the spatiotemporal patterns of spine formation in the basolateral amygdala. Proc Natl Acad Sci U S A (2005) 2.59
Social influences on neuroplasticity: stress and interventions to promote well-being. Nat Neurosci (2012) 2.49
Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. Eur J Neurosci (2003) 2.42
Socio-economic differentials in peripheral biology: cumulative allostatic load. Ann N Y Acad Sci (2010) 2.37
Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell Stem Cell (2013) 2.31
Microglia derived from aging mice exhibit an altered inflammatory profile. Glia (2007) 2.29
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein. Proc Natl Acad Sci U S A (2008) 2.27
Stress and the adolescent brain. Ann N Y Acad Sci (2006) 2.22
Uncovering the mechanisms of estrogen effects on hippocampal function. Front Neuroendocrinol (2007) 2.13
Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex. J Comp Neurol (2008) 2.07
Association of depression with medical illness: does cortisol play a role? Biol Psychiatry (2004) 2.05
Ultrastructural localization of estrogen receptor beta immunoreactivity in the rat hippocampal formation. J Comp Neurol (2005) 1.97
Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory. Proc Natl Acad Sci U S A (2009) 1.95
Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp Neurol (2005) 1.89
Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proc Natl Acad Sci U S A (2011) 1.82
Gender difference in neural response to psychological stress. Soc Cogn Affect Neurosci (2007) 1.81
Urinary cortisol excretion as a predictor of incident cognitive impairment. Neurobiol Aging (2005) 1.76
Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity. Behav Neurosci (2005) 1.76
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals. Circ Res (2004) 1.74
Estrogen alters hippocampal dendritic spine shape and enhances synaptic protein immunoreactivity and spatial memory in female mice. Proc Natl Acad Sci U S A (2004) 1.72
Regulation of hippocampal H3 histone methylation by acute and chronic stress. Proc Natl Acad Sci U S A (2009) 1.72
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain. J Comp Neurol (2008) 1.72
Effects of chronic stress on hippocampal long-term potentiation. Hippocampus (2002) 1.70
Estrogen and aging affect the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats. J Neurosci (2002) 1.61
The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment: a comparison with tianeptine. Biol Psychiatry (2004) 1.59
Sex differences in angiotensin signaling in bulbospinal neurons in the rat rostral ventrolateral medulla. Am J Physiol Regul Integr Comp Physiol (2008) 1.57
Endocrine and physiological changes in response to chronic corticosterone: a potential model of the metabolic syndrome in mouse. Endocrinology (2010) 1.52
Acid sensitivity and ultrastructure of the retrotrapezoid nucleus in Phox2b-EGFP transgenic mice. J Comp Neurol (2009) 1.52
Stress history and pubertal development interact to shape hypothalamic-pituitary-adrenal axis plasticity. Endocrinology (2006) 1.50
Social inequalities in biomarkers of cardiovascular risk in adolescence. Psychosom Med (2005) 1.48
Estrogen stimulates postsynaptic density-95 rapid protein synthesis via the Akt/protein kinase B pathway. J Neurosci (2003) 1.48
Synaptic cross talk between perisomatic-targeting interneuron classes expressing cholecystokinin and parvalbumin in hippocampus. J Neurosci (2009) 1.47
Stress-induced dendritic remodeling in the prefrontal cortex is circuit specific. Cereb Cortex (2009) 1.46
Disasters and the heart: a review of the effects of earthquake-induced stress on cardiovascular disease. Hypertens Res (2003) 1.45
Involvement of the endocannabinoid system in the neurobehavioural effects of stress and glucocorticoids. Prog Neuropsychopharmacol Biol Psychiatry (2009) 1.44
Stress-induced out-of-context activation of memory. PLoS Biol (2010) 1.42
The role of N-methyl-D-asparate receptors in neurogenesis. Hippocampus (2006) 1.42
Psychobiological allostasis: resistance, resilience and vulnerability. Trends Cogn Sci (2011) 1.40
BDNF induction with mild exercise in the rat hippocampus. Biochem Biophys Res Commun (2007) 1.39
Social disadvantage and adolescent stress. J Adolesc Health (2005) 1.38
Dynamic regulation of mitochondrial function by glucocorticoids. Proc Natl Acad Sci U S A (2009) 1.38
Stress-induced structural remodeling in hippocampus: prevention by lithium treatment. Proc Natl Acad Sci U S A (2004) 1.37
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. J Neurosci (2011) 1.37
Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents. J Neurosci (2010) 1.37
Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase. Neuron (2012) 1.36
Acute selective serotonin reuptake inhibitors increase conditioned fear expression: blockade with a 5-HT(2C) receptor antagonist. Biol Psychiatry (2007) 1.36
Establishing an agenda for translational research on PTSD. Ann N Y Acad Sci (2006) 1.36
Regulation of neurotransmitter release by synapsin III. J Neurosci (2002) 1.34
Maternal influences on adult stress and anxiety-like behavior in C57BL/6J and BALB/cJ mice: a cross-fostering study. Dev Psychobiol (2005) 1.34
Stress-induced redistribution of immune cells--from barracks to boulevards to battlefields: a tale of three hormones--Curt Richter Award winner. Psychoneuroendocrinology (2012) 1.34
BDNF-mediated neurotransmission relies upon a myosin VI motor complex. Nat Neurosci (2006) 1.33
Evidence for reduced experience-dependent dendritic spine plasticity in the aging prefrontal cortex. J Neurosci (2011) 1.32
Estrogen effects on the brain: actions beyond the hypothalamus via novel mechanisms. Behav Neurosci (2012) 1.31
Testosterone cannot activate an adult-like stress response in prepubertal male rats. Neuroendocrinology (2004) 1.30
Chronic restraint stress up-regulates GLT-1 mRNA and protein expression in the rat hippocampus: reversal by tianeptine. Proc Natl Acad Sci U S A (2004) 1.30
Hippocampal formation: shedding light on the influence of sex and stress on the brain. Brain Res Rev (2007) 1.30
NMDA receptor antagonist treatment increases the production of new neurons in the aged rat hippocampus. Neurobiol Aging (2002) 1.30
Amygdala FAAH and anandamide: mediating protection and recovery from stress. Trends Pharmacol Sci (2013) 1.27
Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor. Eur J Neurosci (2008) 1.26
Estrogen promotes stress sensitivity in a prefrontal cortex-amygdala pathway. Cereb Cortex (2010) 1.26
Depression, cortisol, and suppressed cell-mediated immunity in metastatic breast cancer. Brain Behav Immun (2009) 1.26
Mu opioid receptors are in discrete hippocampal interneuron subpopulations. Hippocampus (2002) 1.25
Anxiety and fear behaviors in adult male and female C57BL/6 mice are modulated by maternal separation. Horm Behav (2003) 1.24
Estrogen levels regulate the subcellular distribution of phosphorylated Akt in hippocampal CA1 dendrites. J Neurosci (2003) 1.23
Innate immunity receptor CD36 promotes cerebral amyloid angiopathy. Proc Natl Acad Sci U S A (2013) 1.21
Ultrastructural evidence for pre- and postsynaptic localization of Cav1.2 L-type Ca2+ channels in the rat hippocampus. J Comp Neurol (2008) 1.19
Estradiol increases pre- and post-synaptic proteins in the CA1 region of the hippocampus in female rhesus macaques (Macaca mulatta). Endocrinology (2003) 1.19
Sexually dimorphic expression of estrogen receptor beta in the anteroventral periventricular nucleus of the rat preoptic area: implication in luteinizing hormone surge. Proc Natl Acad Sci U S A (2002) 1.18
Interactive effects of stress and aging on structural plasticity in the prefrontal cortex. J Neurosci (2010) 1.18
Evidence that estrogen directly and indirectly modulates C1 adrenergic bulbospinal neurons in the rostral ventrolateral medulla. Brain Res (2006) 1.18
Opioid systems in the dentate gyrus. Prog Brain Res (2007) 1.17
Chronic juvenile stress produces corticolimbic dendritic architectural remodeling and modulates emotional behavior in male and female rats. Psychoneuroendocrinology (2011) 1.17
Brain dendritic cells in ischemic stroke: time course, activation state, and origin. Brain Behav Immun (2009) 1.16
Acute and chronic restraint stress alter the incidence of social conflict in male rats. Horm Behav (2003) 1.16