Published in J Neurosci on July 26, 2006
Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci (2009) 6.22
Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol (2008) 4.82
The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology (2010) 4.82
Chronic stress, drug use, and vulnerability to addiction. Ann N Y Acad Sci (2008) 4.60
Central role of the brain in stress and adaptation: links to socioeconomic status, health, and disease. Ann N Y Acad Sci (2010) 3.95
Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol Psychiatry (2011) 3.62
Socioeconomic status and the brain: mechanistic insights from human and animal research. Nat Rev Neurosci (2010) 3.30
Stress- and allostasis-induced brain plasticity. Annu Rev Med (2011) 3.06
Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. J Neurosci (2010) 2.84
The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission. Nat Rev Neurosci (2011) 2.82
Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders. Neuropharmacology (2011) 2.79
Brain on stress: how the social environment gets under the skin. Proc Natl Acad Sci U S A (2012) 2.77
The ageing cortical synapse: hallmarks and implications for cognitive decline. Nat Rev Neurosci (2012) 2.76
Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: role of corticosterone-mediated apical dendritic atrophy. Proc Natl Acad Sci U S A (2008) 2.71
Shifting and stopping: fronto-striatal substrates, neurochemical modulation and clinical implications. Philos Trans R Soc Lond B Biol Sci (2007) 2.66
The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course. Neuron (2013) 2.59
Protective and damaging effects of stress mediators: central role of the brain. Dialogues Clin Neurosci (2006) 2.50
Social influences on neuroplasticity: stress and interventions to promote well-being. Nat Neurosci (2012) 2.49
Psychosocial stress reversibly disrupts prefrontal processing and attentional control. Proc Natl Acad Sci U S A (2009) 2.49
Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide. Neurosci Biobehav Rev (2009) 2.44
Stress-induced prefrontal reorganization and executive dysfunction in rodents. Neurosci Biobehav Rev (2008) 2.33
Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance. Nat Neurosci (2013) 2.14
Resting-state connectivity biomarkers define neurophysiological subtypes of depression. Nat Med (2016) 2.12
Child development in the context of adversity: experiential canalization of brain and behavior. Am Psychol (2012) 2.12
Stress and memory: behavioral effects and neurobiological mechanisms. Neural Plast (2007) 2.10
Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex. J Comp Neurol (2008) 2.07
Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapses. Neuron (2012) 1.99
Stress and anxiety: structural plasticity and epigenetic regulation as a consequence of stress. Neuropharmacology (2011) 1.98
Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex. Neuropsychopharmacology (2015) 1.97
Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory. Proc Natl Acad Sci U S A (2009) 1.95
Dendritic spine pathology in schizophrenia. Neuroscience (2012) 1.91
Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex. Neuron (2012) 1.83
Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling. Ann N Y Acad Sci (2010) 1.71
Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery. Neuroscience (2009) 1.68
The effects of chronic stress on hippocampal morphology and function: an evaluation of chronic restraint paradigms. Brain Res (2007) 1.66
Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory. Mol Psychiatry (2010) 1.66
Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease. Neurosci Biobehav Rev (2008) 1.65
Epigenetics of the depressed brain: role of histone acetylation and methylation. Neuropsychopharmacology (2012) 1.64
Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo. Proc Natl Acad Sci U S A (2011) 1.53
Experience and the developing prefrontal cortex. Proc Natl Acad Sci U S A (2012) 1.52
A history of corticosterone exposure regulates fear extinction and cortical NR2B, GluR2/3, and BDNF. Neuropsychopharmacology (2008) 1.51
Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress. Proc Natl Acad Sci U S A (2009) 1.49
Mechanisms of stress in the brain. Nat Neurosci (2015) 1.47
Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons. Hippocampus (2011) 1.46
Stress-induced dendritic remodeling in the prefrontal cortex is circuit specific. Cereb Cortex (2009) 1.46
Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants. J Neurosci (2012) 1.45
Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses. Biol Psychiatry (2013) 1.44
Obesity diminishes synaptic markers, alters microglial morphology, and impairs cognitive function. Proc Natl Acad Sci U S A (2015) 1.43
Hippocampal formation: shedding light on the influence of sex and stress on the brain. Brain Res Rev (2007) 1.30
CNTRICS final task selection: executive control. Schizophr Bull (2008) 1.29
Cumulative adversity and smaller gray matter volume in medial prefrontal, anterior cingulate, and insula regions. Biol Psychiatry (2012) 1.29
Sex-specific neuroanatomical correlates of fear expression in prefrontal-amygdala circuits. Biol Psychiatry (2014) 1.24
Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression. Dialogues Clin Neurosci (2009) 1.23
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. Eur Arch Psychiatry Clin Neurosci (2009) 1.23
Corticotropin-releasing factor in the norepinephrine nucleus, locus coeruleus, facilitates behavioral flexibility. Neuropsychopharmacology (2011) 1.20
NMDA receptor blockade alters stress-induced dendritic remodeling in medial prefrontal cortex. Cereb Cortex (2011) 1.19
Interactive effects of stress and aging on structural plasticity in the prefrontal cortex. J Neurosci (2010) 1.18
Associations between early life adversity and executive function in children adopted internationally from orphanages. Proc Natl Acad Sci U S A (2012) 1.18
Depression: a repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition? Neurosci Biobehav Rev (2010) 1.17
Chronic juvenile stress produces corticolimbic dendritic architectural remodeling and modulates emotional behavior in male and female rats. Psychoneuroendocrinology (2011) 1.17
The ever-changing brain: cellular and molecular mechanisms for the effects of stressful experiences. Dev Neurobiol (2012) 1.15
Stress risk factors and stress-related pathology: neuroplasticity, epigenetics and endophenotypes. Stress (2011) 1.14
Stress and the developing adolescent brain. Neuroscience (2012) 1.13
Making a bad thing worse: adverse effects of stress on drug addiction. J Clin Invest (2008) 1.13
Structural variations in prefrontal cortex mediate the relationship between early childhood stress and spatial working memory. J Neurosci (2012) 1.11
Arg kinase regulates prefrontal dendritic spine refinement and cocaine-induced plasticity. J Neurosci (2012) 1.11
Chronic stress effects on dendritic morphology in medial prefrontal cortex: sex differences and estrogen dependence. Neuroscience (2009) 1.11
Corticosteroid-induced neural remodeling predicts behavioral vulnerability and resilience. J Neurosci (2013) 1.10
Action control is mediated by prefrontal BDNF and glucocorticoid receptor binding. Proc Natl Acad Sci U S A (2012) 1.09
Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress. J Neurosci (2008) 1.09
Brain plasticity and behaviour in the developing brain. J Can Acad Child Adolesc Psychiatry (2011) 1.08
Effects of chronic intermittent ethanol exposure on orbitofrontal and medial prefrontal cortex-dependent behaviors in mice. Behav Neurosci (2011) 1.08
Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice. J Neurosci (2012) 1.07
Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress. Cereb Cortex (2011) 1.07
Parenting and plasticity. Trends Neurosci (2010) 1.06
Postnatal binge-like alcohol exposure decreases dendritic complexity while increasing the density of mature spines in mPFC Layer II/III pyramidal neurons. Synapse (2010) 1.06
Illness progression, recent stress, and morphometry of hippocampal subfields and medial prefrontal cortex in major depression. Biol Psychiatry (2014) 1.06
Stress weakens prefrontal networks: molecular insults to higher cognition. Nat Neurosci (2015) 1.06
Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia. Drug Discov Today (2009) 1.05
An excitatory synapse hypothesis of depression. Trends Neurosci (2015) 1.05
Stress-induced dendritic remodeling in the medial prefrontal cortex: effects of circuit, hormones and rest. Brain Res (2009) 1.05
Effect of age, behaviour and social environment on honey bee brain plasticity. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2009) 1.04
Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress. Front Neurosci (2011) 1.04
Corticosterone regulates pERK1/2 map kinase in a chronic depression model. Ann N Y Acad Sci (2008) 1.04
Glucocorticoid actions on synapses, circuits, and behavior: implications for the energetics of stress. Front Neuroendocrinol (2013) 1.03
Recognizing Resilience: Learning from the Effects of Stress on the Brain. Neurobiol Stress (2015) 1.03
The emotional Stroop task and posttraumatic stress disorder: a meta-analysis. Clin Psychol Rev (2011) 1.01
Prenatal stress and subsequent exposure to chronic mild stress influence dendritic spine density and morphology in the rat medial prefrontal cortex. BMC Neurosci (2007) 1.00
Beneficial effects of desipramine on cognitive function of chronically stressed rats are mediated by alpha1-adrenergic receptors in medial prefrontal cortex. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.99
Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression. Neuroscience (2012) 0.99
Protein kinase C activity is associated with prefrontal cortical decline in aging. Neurobiol Aging (2007) 0.98
Neighborhood matters: divergent patterns of stress-induced plasticity across the brain. Nat Neurosci (2015) 0.96
Chronic stress-induced alterations of dendritic spine subtypes predict functional decrements in an hypothalamo-pituitary-adrenal-inhibitory prefrontal circuit. J Neurosci (2013) 0.95
Higher education is an age-independent predictor of white matter integrity and cognitive control in late adolescence. Dev Sci (2013) 0.95
Dendritic growth in medial prefrontal cortex and cognitive flexibility are enhanced during the postpartum period. J Neurosci (2010) 0.95
Ethanol reduces neuronal excitability of lateral orbitofrontal cortex neurons via a glycine receptor dependent mechanism. Neuropsychopharmacology (2013) 0.95
The effects of abused drugs on adolescent development of corticolimbic circuitry and behavior. Neuroscience (2013) 0.94
Neighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adults. Arch Gen Psychiatry (2011) 0.94
Effects of chronic immobilization stress on anxiety-like behavior and basolateral amygdala morphology in Fmr1 knockout mice. Neuroscience (2011) 0.93
Are BDNF and glucocorticoid activities calibrated? Neuroscience (2012) 0.92
Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci (2009) 11.02
Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention. JAMA (2009) 7.90
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science (2006) 5.89
Allostatic load biomarkers of chronic stress and impact on health and cognition. Neurosci Biobehav Rev (2009) 5.40
Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry (2005) 4.81
Stress, memory and the amygdala. Nat Rev Neurosci (2009) 4.57
White matter changes in schizophrenia: evidence for myelin-related dysfunction. Arch Gen Psychiatry (2003) 4.25
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. J Neuropathol Exp Neurol (2012) 3.77
Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol (2014) 3.75
Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. PLoS One (2008) 3.74
Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex. Cereb Cortex (2005) 3.71
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2006) 3.61
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci (2010) 3.41
Course of illness, hippocampal function, and hippocampal volume in major depression. Proc Natl Acad Sci U S A (2003) 3.29
Geometry and structural plasticity of synaptic connectivity. Neuron (2002) 3.23
Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus. J Comp Neurol (2004) 3.12
The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease. Neurosci Biobehav Rev (2004) 3.10
Adverse childhood experiences, allostasis, allostatic load, and age-related disease. Physiol Behav (2011) 3.04
The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. Trends Neurosci (2010) 3.02
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J Neurosci (2005) 2.94
Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha. Endocrinology (2003) 2.85
The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission. Nat Rev Neurosci (2011) 2.82
Allostatic load as a predictor of functional decline. MacArthur studies of successful aging. J Clin Epidemiol (2002) 2.78
Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles. Proc Natl Acad Sci U S A (2004) 2.74
New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci (2013) 2.65
Minicolumnar abnormalities in autism. Acta Neuropathol (2006) 2.62
The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course. Neuron (2013) 2.59
Stress duration modulates the spatiotemporal patterns of spine formation in the basolateral amygdala. Proc Natl Acad Sci U S A (2005) 2.59
Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease. FASEB J (2004) 2.56
Variability of Broca's area homologue in African great apes: implications for language evolution. Anat Rec A Discov Mol Cell Evol Biol (2003) 2.52
Social influences on neuroplasticity: stress and interventions to promote well-being. Nat Neurosci (2012) 2.49
NMDA receptors subserve persistent neuronal firing during working memory in dorsolateral prefrontal cortex. Neuron (2013) 2.46
Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. Eur J Neurosci (2003) 2.42
Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons. Proc Natl Acad Sci U S A (2003) 2.41
Cyclic estrogen replacement improves cognitive function in aged ovariectomized rhesus monkeys. J Neurosci (2003) 2.40
Rayburst sampling, an algorithm for automated three-dimensional shape analysis from laser scanning microscopy images. Nat Protoc (2006) 2.38
Socio-economic differentials in peripheral biology: cumulative allostatic load. Ann N Y Acad Sci (2010) 2.37
Neuropathological findings in autism. Brain (2004) 2.34
Microglia derived from aging mice exhibit an altered inflammatory profile. Glia (2007) 2.29
Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures. Cell (2012) 2.29
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein. Proc Natl Acad Sci U S A (2008) 2.27
Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment. J Neurosci (2010) 2.25
Estrogen alters spine number and morphology in prefrontal cortex of aged female rhesus monkeys. J Neurosci (2006) 2.24
Stress and the adolescent brain. Ann N Y Acad Sci (2006) 2.22
IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity. J Neurosci (2011) 2.15
Uncovering the mechanisms of estrogen effects on hippocampal function. Front Neuroendocrinol (2007) 2.13
Diffusion tensor imaging findings in first-episode and chronic schizophrenia patients. Am J Psychiatry (2008) 2.11
The aging brain: morphomolecular senescence of cortical circuits. Trends Neurosci (2004) 2.10
Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex. J Comp Neurol (2008) 2.07
Association of depression with medical illness: does cortisol play a role? Biol Psychiatry (2004) 2.05
Cytoarchitecture of the human cerebral cortex: MR microscopy of excised specimens at 9.4 Tesla. AJNR Am J Neuroradiol (2002) 1.98
Stress and anxiety: structural plasticity and epigenetic regulation as a consequence of stress. Neuropharmacology (2011) 1.98
Ultrastructural localization of estrogen receptor beta immunoreactivity in the rat hippocampal formation. J Comp Neurol (2005) 1.97
Changes in the structural complexity of the aged brain. Aging Cell (2007) 1.96
Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory. Proc Natl Acad Sci U S A (2009) 1.95
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. FASEB J (2005) 1.90
Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp Neurol (2005) 1.89
Functional trade-offs in white matter axonal scaling. J Neurosci (2008) 1.88
Clinicopathological validation study of four sets of clinical criteria for vascular dementia. Am J Psychiatry (2002) 1.88
Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis. Proc Natl Acad Sci U S A (2003) 1.86
In Vivo 3D Digital Atlas Database of the Adult C57BL/6J Mouse Brain by Magnetic Resonance Microscopy. Front Neuroanat (2008) 1.85
Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys. Cereb Cortex (2003) 1.83
Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proc Natl Acad Sci U S A (2011) 1.82
Gender difference in neural response to psychological stress. Soc Cogn Affect Neurosci (2007) 1.81
Evolution of increased glia-neuron ratios in the human frontal cortex. Proc Natl Acad Sci U S A (2006) 1.77
Urinary cortisol excretion as a predictor of incident cognitive impairment. Neurobiol Aging (2005) 1.76
Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity. Behav Neurosci (2005) 1.76
Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke (2004) 1.74
Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain. Proc Natl Acad Sci U S A (2008) 1.73
Estrogen alters hippocampal dendritic spine shape and enhances synaptic protein immunoreactivity and spatial memory in female mice. Proc Natl Acad Sci U S A (2004) 1.72
Regulation of hippocampal H3 histone methylation by acute and chronic stress. Proc Natl Acad Sci U S A (2009) 1.72
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain. J Comp Neurol (2008) 1.72
The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans. Brain Struct Funct (2010) 1.71
Effects of chronic stress on hippocampal long-term potentiation. Hippocampus (2002) 1.70
Prolonged myelination in human neocortical evolution. Proc Natl Acad Sci U S A (2012) 1.64
Estrogen and aging affect the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats. J Neurosci (2002) 1.61
High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy. Nat Protoc (2011) 1.59
The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment: a comparison with tianeptine. Biol Psychiatry (2004) 1.59
Interactive effects of age and estrogen on cognition and pyramidal neurons in monkey prefrontal cortex. Proc Natl Acad Sci U S A (2007) 1.56
Cetaceans have complex brains for complex cognition. PLoS Biol (2007) 1.55
Morphological substrates of cognitive decline in nonagenarians and centenarians: a new paradigm? J Neurol Sci (2007) 1.52