Published in J Membr Biol on February 21, 2008
The transferrin receptor and the targeted delivery of therapeutic agents against cancer. Biochim Biophys Acta (2011) 1.64
A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250. Anal Biochem (1977) 14.08
The basic science of gene therapy. Science (1993) 5.94
Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem (1995) 4.39
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry (1996) 4.06
Drug targeting. Eur J Pharm Sci (2000) 1.91
Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. J Biol Chem (1996) 1.55
Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery. Nat Biotechnol (1997) 1.45
A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc Natl Acad Sci U S A (1996) 1.44
A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA. Proc Natl Acad Sci U S A (1996) 1.38
Biophysical characterization of cationic lipid: DNA complexes. Biochim Biophys Acta (1997) 1.30
The role of helper lipids in cationic liposome-mediated gene transfer. Biophys J (1996) 1.30
Endosomes, lysosomes: their implication in gene transfer. Adv Drug Deliv Rev (2000) 1.24
Use of poly(ethylene glycol)-lipid conjugates to regulate the surface attributes and transfection activity of lipid-DNA particles. J Pharm Sci (2000) 1.18
Factors governing the assembly of cationic phospholipid-DNA complexes. Biophys J (2000) 1.17
Ultrasound enhances reporter gene expression after transfection of vascular cells in vitro. Circulation (1999) 1.16
Inclusion of cholesterol in DOTAP transfection complexes increases the delivery of DNA to cells in vitro in the presence of serum. Gene Ther (1998) 1.14
Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection efficiency. Mol Ther (2005) 1.11
Biological barriers to cellular delivery of lipid-based DNA carriers. Adv Drug Deliv Rev (1999) 1.09
Cationic lipid-mediated gene transfer: effect of serum on cellular uptake and intracellular fate of lipopolyamine/DNA complexes. Biochim Biophys Acta (1998) 1.05
Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery. J Biol Chem (2001) 1.04
Structure of in-serum transfecting DNA-cationic lipid complexes. FEBS Lett (1997) 0.99
Lipid transfer between cationic vesicles and lipid-DNA lipoplexes: effect of serum. Biochim Biophys Acta (2005) 0.98
Effects of temperature and lipid composition on the serum albumin-induced aggregation and fusion of small unilamellar vesicles. Biochim Biophys Acta (1981) 0.97
Receptor ligand-facilitated gene transfer: enhancement of liposome-mediated gene transfer and expression by transferrin. Hum Gene Ther (1996) 0.97
Interference of poly(ethylene glycol)-lipid analogues with cationic-lipid-mediated delivery of oligonucleotides; role of lipid exchangeability and non-lamellar transitions. Biochem J (2002) 0.97
A sterically stabilized immunolipoplex for systemic administration of a therapeutic gene. Gene Ther (2004) 0.96
Evidence for targeted gene transfer by receptor-mediated endocytosis. Stable expression following insulin-directed entry of NEO into HepG2 cells. Biochem Pharmacol (1990) 0.96
Physico-chemical characterisation and transfection efficiency of lipid-based gene delivery complexes. Int J Pharm (1999) 0.96
Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum. Biochim Biophys Acta (2000) 0.95
DNA-based immunotherapeutics for the treatment of allergic disease. Immunol Rev (2001) 0.94
Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides. Gene Ther (1999) 0.93
A novel series of amphiphilic imidazolinium compounds for in vitro and in vivo gene delivery. Biochemistry (1995) 0.93
Physicochemical optimisation of plasmid delivery by cationic lipids. J Gene Med (2004) 0.93
Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency. Biophys J (2002) 0.93
Biodistribution and gene expression of lipid/plasmid complexes after systemic administration. Hum Gene Ther (1998) 0.91
Gene-based immunotherapy for human immunodeficiency virus infection and acquired immunodeficiency syndrome. Hum Gene Ther (2006) 0.88
Reversible mode of binding of serum proteins to DOTAP/cholesterol Lipoplexes: a possible explanation for intravenous lipofection efficiency. Hum Gene Ther (2005) 0.87
The use of fluorescence resonance energy transfer to monitor dynamic changes of lipid-DNA interactions during lipoplex formation. Biochim Biophys Acta (2003) 0.87
Stable and monodisperse lipoplex formulations for gene delivery. Gene Ther (1998) 0.86
Evaluation of lipid-based reagents to mediate intracellular gene delivery. Biochim Biophys Acta (2002) 0.86
Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neurons. Exp Neurol (2004) 0.86
Transfection of oral cancer cells mediated by transferrin-associated lipoplexes: mechanisms of cell death induced by herpes simplex virus thymidine kinase/ganciclovir therapy. Biochim Biophys Acta (2006) 0.84
Gene therapeutic strategies for neurodegenerative diseases. Curr Opin Mol Ther (2000) 0.83
Characterization of cationic lipid DNA transfection complexes differing in susceptability to serum inhibition. BMC Biotechnol (2002) 0.82
Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles. Gene Ther (1998) 0.81
Effect of "helper lipid" on lipoplex electrostatics. Biochim Biophys Acta (2005) 0.81
Cancer gene therapy clinical trials: lessons for the future. Br J Cancer (2001) 0.80
Polymorphism of pyridinium amphiphiles for gene delivery: influence of ionic strength, helper lipid content, and plasmid DNA complexation. Biophys J (2004) 0.80
Efficient gene transfer to EGF receptor overexpressing cancer cells by means of EGF-labeled cationic liposomes. Biochem Biophys Res Commun (1996) 0.80
Human immunodeficiency virus type-1 (HIV-1) infection increases the sensitivity of macrophages and THP-1 cells to cytotoxicity by cationic liposomes. Biochim Biophys Acta (1996) 0.78
Kinetic analysis of the initial steps involved in lipoplex--cell interactions: effect of various factors that influence transfection activity. Biochim Biophys Acta (2001) 0.78
Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury. Gene Ther (2005) 0.77
Transfection of cultured myoblasts in high serum concentration with DODAC:DOPE liposomes. Gene Ther (1998) 0.76
Benzodiazepine receptor binding in the spontaneously epileptic rat and its parent strains. Exp Neurol (1991) 0.75
Fusion of small unilamellar vesicles induced by bovine serum albumin fragments. Braz J Med Biol Res (1983) 0.75
Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity. J Control Release (2002) 2.21
miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production. Immunology (2012) 1.43
Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease. PLoS One (2008) 1.34
Cationic liposomes for gene delivery. Expert Opin Drug Deliv (2005) 1.15
Sterols as anticancer agents: synthesis of ring-B oxygenated steroids, cytotoxic profile, and comprehensive SAR analysis. J Med Chem (2010) 1.14
Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3? Hum Mol Genet (2010) 1.06
MicroRNAs as Molecular Targets for Cancer Therapy: On the Modulation of MicroRNA Expression. Pharmaceuticals (Basel) (2013) 1.04
Bcl-2-targeted antisense therapy (Oblimersen sodium): towards clinical reality. Rev Recent Clin Trials (2006) 1.01
Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges. Acc Chem Res (2012) 0.97
Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease. Hum Mol Genet (2008) 0.95
On the mechanisms of the internalization of S4(13)-PV cell-penetrating peptide. Biochem J (2005) 0.94
Efficient chemoenzymatic synthesis, cytotoxic evaluation, and SAR of epoxysterols. J Med Chem (2009) 0.94
Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment. Mol Ther Nucleic Acids (2013) 0.94
Mechanisms of singlet-oxygen and superoxide-ion generation by porphyrins and bacteriochlorins and their implications in photodynamic therapy. Chemistry (2010) 0.93
Caveolae as an additional route for influenza virus endocytosis in MDCK cells. Cell Mol Biol Lett (2004) 0.93
Notch and lymphopoiesis: a view from the microenvironment. Semin Immunol (2003) 0.92
Transferrin receptor-targeted liposomes encapsulating anti-BCR-ABL siRNA or asODN for chronic myeloid leukemia treatment. Bioconjug Chem (2010) 0.91
Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: evidence from intracellular fluorescence and increased photodynamic efficacy in vitro. Free Radic Biol Med (2012) 0.91
MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma. Hum Mol Genet (2012) 0.90
Biodistribution and photodynamic efficacy of a water-soluble, stable, halogenated bacteriochlorin against melanoma. ChemMedChem (2011) 0.87
Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neurons. Exp Neurol (2004) 0.86
Ciprofloxacin sensitizes hormone-refractory prostate cancer cell lines to doxorubicin and docetaxel treatment on a schedule-dependent manner. Cancer Chemother Pharmacol (2008) 0.85
Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three independent signals. J Virol (2006) 0.85
Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c. J Control Release (2010) 0.84
Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment. Int J Pharm (2012) 0.84
Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment. Biotechnol Bioeng (2010) 0.84
Transfection of oral cancer cells mediated by transferrin-associated lipoplexes: mechanisms of cell death induced by herpes simplex virus thymidine kinase/ganciclovir therapy. Biochim Biophys Acta (2006) 0.84
Comparison of the efficiency of complexes based on S4(13)-PV cell-penetrating peptides in plasmid DNA and siRNA delivery. Mol Pharm (2013) 0.83
Ligand-guided optimization of CXCR4 homology models for virtual screening using a multiple chemotype approach. J Comput Aided Mol Des (2010) 0.83
Cationic liposomes for gene delivery: novel cationic lipids and enhancement by proteins and peptides. Curr Med Chem (2003) 0.83
A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides. J Control Release (2010) 0.83
Delivery of antiviral agents in liposomes. Methods Enzymol (2005) 0.83
Liposomal imatinib-mitoxantrone combination: formulation development and therapeutic evaluation in an animal model of prostate cancer. Prostate (2011) 0.83
New halogenated water-soluble chlorin and bacteriochlorin as photostable PDT sensitizers: synthesis, spectroscopy, photophysics, and in vitro photosensitizing efficacy. ChemMedChem (2010) 0.83
Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: impact on the treatment of breast cancer. Breast Cancer Res Treat (2011) 0.82
Structural analysis of hepatitis C virus core-E1 signal peptide and requirements for cleavage of the genotype 3a signal sequence by signal peptide peptidase. J Virol (2012) 0.81
Cell-penetrating peptides as nucleic acid delivery systems: from biophysics to biological applications. Curr Pharm Des (2013) 0.81
African swine fever virus p37 structural protein is localized in nuclear foci containing the viral DNA at early post-infection times. Virus Res (2007) 0.81
Targeting of sterically stabilised pH-sensitive liposomes to human T-leukaemia cells. Eur J Pharm Biopharm (2005) 0.80
PDGF-B-mediated downregulation of miR-21: new insights into PDGF signaling in glioblastoma. Hum Mol Genet (2012) 0.80
The cadherin superfamily in Anopheles gambiae: a comparative study with Drosophila melanogaster. Comp Funct Genomics (2005) 0.79
Fluorescent probes for monitoring virus fusion kinetics: comparative evaluation of reliability. Biochim Biophys Acta (2002) 0.79
S4(13)-PV cell-penetrating peptide forms nanoparticle-like structures to gain entry into cells. Bioconjug Chem (2010) 0.79
Challenging the future of siRNA therapeutics against cancer: the crucial role of nanotechnology. Cell Mol Life Sci (2013) 0.79
Design of peptide-targeted liposomes containing nucleic acids. Biochim Biophys Acta (2009) 0.79
S4(13)-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA. J Gene Med (2008) 0.79
Selective cytotoxicity of oxysterols through structural modulation on rings A and B. Synthesis, in vitro evaluation, and SAR. J Med Chem (2011) 0.78
Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect. Oncol Rep (2012) 0.78
Interaction of S413-PV cell penetrating peptide with model membranes: relevance to peptide translocation across biological membranes. J Pept Sci (2007) 0.78
Cellular uptake of S413-PV peptide occurs upon conformational changes induced by peptide-membrane interactions. Biochim Biophys Acta (2006) 0.77
Tissue uptake study and photodynamic therapy of melanoma-bearing mice with a nontoxic, effective chlorin. ChemMedChem (2011) 0.77
Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform. Nanomedicine (Lond) (2013) 0.77
S4(13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: implications for cell internalization. Biochim Biophys Acta (2011) 0.77
African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection. Vet Microbiol (2007) 0.77
Novel oleanolic vinyl boronates: synthesis and antitumor activity. Eur J Med Chem (2013) 0.77
Imidazole-grafted chitosan-mediated gene delivery: in vitro study on transfection, intracellular trafficking and degradation. Nanomedicine (Lond) (2011) 0.77
Impact of PLK-1 silencing on endothelial cells and cancer cells of diverse histological origin. Curr Gene Ther (2013) 0.76
Chitosan-based gene delivery vectors targeted to the peripheral nervous system. J Biomed Mater Res A (2010) 0.76
Schedule treatment design and quantitative in vitro evaluation of chemotherapeutic combinations for metastatic prostate cancer therapy. Cancer Chemother Pharmacol (2010) 0.76
Sterically stabilized ph-sensitive liposomes. Methods Enzymol (2004) 0.76
Impact of anti-PLK1 siRNA-containing F3-targeted liposomes on the viability of both cancer and endothelial cells. Eur J Pharm Biopharm (2013) 0.76
Application of thermoresponsive PNIPAAM-b-PAMPTMA diblock copolymers in siRNA delivery. Mol Pharm (2014) 0.75
Physicochemical properties of transferrin-associated lipopolyplexes and their role in biological activity. Colloids Surf B Biointerfaces (2009) 0.75
Technology evaluation: LErafAON, NeoPharm. Curr Opin Mol Ther (2003) 0.75
Polyethylenimine of various molecular weights as adjuvant for transfection mediated by cationic liposomes. Mol Membr Biol (2009) 0.75
Gemini surfactants mediate efficient mitochondrial gene delivery and expression. Mol Pharm (2015) 0.75
Development, characterization and in vitro evaluation of single or co-loaded imatinib mesylate liposomal formulations. J Nanosci Nanotechnol (2012) 0.75
Biophysical characterization of cationic liposome-DNA complexes and their interaction with cells. Methods Enzymol (2003) 0.75
Impact of combined exercise on chronic obstructive pulmonary patients' state of health. Rev Port Pneumol (2010) 0.75