Published in Autophagy on February 23, 2008
Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury. PLoS One (2012) 1.30
Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy. Oncogene (2015) 1.11
Mitochondrial targets for stroke: focusing basic science research toward development of clinically translatable therapeutics. Stroke (2009) 1.01
Death and survival of neuronal and astrocytic cells in ischemic brain injury: a role of autophagy. Acta Pharmacol Sin (2011) 0.99
Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage. Stroke (2014) 0.99
Crosstalk Between Endoplasmic Reticulum Stress, Oxidative Stress, and Autophagy: Potential Therapeutic Targets for Acute CNS Injuries. Mol Neurobiol (2014) 0.95
Calorie restriction and stroke. Exp Transl Stroke Med (2011) 0.95
Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells. Int J Oncol (2014) 0.89
Autophagy and apoptosis are differentially induced in neurons and astrocytes treated with an in vitro mimic of the ischemic penumbra. PLoS One (2012) 0.89
The role of the ubiquitin proteasome system in ischemia and ischemic tolerance. Neuroscientist (2009) 0.86
An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons. Brain Res (2012) 0.85
Stroke injury, cognitive impairment and vascular dementia. Biochim Biophys Acta (2016) 0.80
Apoptosis and antitumor effects induced by the combination of an mTOR inhibitor and an autophagy inhibitor in human osteosarcoma MG63 cells. Int J Oncol (2015) 0.80
Cinobufagin induces autophagy-mediated cell death in human osteosarcoma U2OS cells through the ROS/JNK/p38 signaling pathway. Oncol Rep (2016) 0.79
MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3. Int J Mol Sci (2016) 0.78
Electroacupuncture Ameliorates Cerebral Ischemia-Reperfusion Injury by Regulation of Autophagy and Apoptosis. Evid Based Complement Alternat Med (2016) 0.77
Autophagy biomarkers in CSF correlates with infarct size, clinical severity and neurological outcome in AIS patients. J Transl Med (2015) 0.77
Alleviation of autophagy by knockdown of Beclin-1 enhances susceptibility of hippocampal neurons to proapoptotic signals induced by amino acid starvation. Histochem Cell Biol (2012) 0.77
Dynamic changes in neuronal autophagy and apoptosis in the ischemic penumbra following permanent ischemic stroke. Neural Regen Res (2016) 0.76
Inhibition of autophagy blocks cathepsins-tBid-mitochondrial apoptotic signaling pathway via stabilization of lysosomal membrane in ischemic astrocytes. Cell Death Dis (2017) 0.75
Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway. Int J Mol Med (2015) 0.75
Chlamydia trachomatis: The persistent pathogen. Clin Vaccine Immunol (2017) 0.75
Inhibition of autophagy attenuated curcumol-induced apoptosis in MG-63 human osteosarcoma cells via Janus kinase signaling pathway. Oncol Lett (2017) 0.75
Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol (2003) 2.42
Parkinson patient fibroblasts show increased alpha-synuclein expression. Exp Neurol (2008) 1.79
The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma. Mol Cancer Res (2010) 1.41
Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD). Mol Biol Cell (2006) 1.26
Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells. J Neurooncol (2010) 1.22
Vascular endothelial growth factor protects cultured rat hippocampal neurons against hypoxic injury via an antiexcitotoxic, caspase-independent mechanism. J Cereb Blood Flow Metab (2002) 1.20
TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling. J Cell Biol (2005) 1.19
Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis. J Cell Sci (2003) 1.13
Coincident enrichment of phosphorylated IkappaBalpha, activated IKK, and phosphorylated p65 in the axon initial segment of neurons. Mol Cell Neurosci (2006) 1.11
Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. J Biol Chem (2001) 1.05
Pharmacological inhibition of Bcl-2 family members reactivates TRAIL-induced apoptosis in malignant glioma. J Neurooncol (2007) 1.04
STAT3 silencing inhibits glioma single cell infiltration and tumor growth. Neuro Oncol (2013) 1.02
Dietary curcumin attenuates glioma growth in a syngeneic mouse model by inhibition of the JAK1,2/STAT3 signaling pathway. Clin Cancer Res (2010) 1.02
Knockdown of TFPI-2 promotes migration and invasion of glioma cells. Neurosci Lett (2011) 1.01
Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis. FEBS J (2008) 1.01
Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis. J Biol Chem (2003) 1.01
sAPPalpha antagonizes dendritic degeneration and neuron death triggered by proteasomal stress. Mol Cell Neurosci (2010) 1.00
The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas. BMC Cancer (2010) 0.98
Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU-induced oxidative stress and cell death. Apoptosis (2013) 0.92
Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing. Biochim Biophys Acta (2010) 0.90
Neuronal apoptosis: BH3-only proteins the real killers? J Bioenerg Biomembr (2004) 0.90
BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells. Neoplasia (2008) 0.89
The amyloid precursor protein potentiates CHOP induction and cell death in response to ER Ca2+ depletion. Biochim Biophys Acta (2006) 0.87
Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effects. PLoS One (2008) 0.86
The interaction of beta-amyloid protein with cellular membranes stimulates its own production. Biochim Biophys Acta (2009) 0.86
Ceramide-induced apoptosis of D283 medulloblastoma cells requires mitochondrial respiratory chain activity but occurs independently of caspases and is not sensitive to Bcl-xL overexpression. J Neurochem (2002) 0.83
Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain. Mol Cell Proteomics (2013) 0.82
Bid and calpains cooperate to trigger oxaliplatin-induced apoptosis of cervical carcinoma HeLa cells. Mol Pharmacol (2009) 0.80
Anti-tissue factor (TF9-10H10) treatment reduces tumor cell invasiveness in a novel migratory glioma model. Neuropathology (2013) 0.80
Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation. J Biol Chem (2011) 0.79
The pro-migratory and pro-invasive role of the procoagulant tissue factor in malignant gliomas. Cell Adh Migr (2011) 0.79
A functional yeast survival screen of tumor-derived cDNA libraries designed to identify anti-apoptotic mammalian oncogenes. PLoS One (2013) 0.76
Quantifying the autophagy-triggering effects of drugs in cell spheroids with live fluorescence microscopy. Methods Mol Biol (2014) 0.75