Published in Clin Pharmacol Ther on March 05, 2008
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA (2009) 6.80
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA (2010) 6.29
A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ (2009) 6.21
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy. Clin Pharmacol Ther (2011) 3.53
Cost-effectiveness of cytochrome P450 2C19 genotype screening for selection of antiplatelet therapy with clopidogrel or prasugrel. Pharmacotherapy (2012) 2.49
Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19*17. Br J Clin Pharmacol (2010) 1.66
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action. Annu Rev Pharmacol Toxicol (2012) 1.41
Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease. Eur Heart J (2009) 1.27
Genetic polymorphisms of CYP2C19 influences the response to clopidogrel in ischemic heart disease patients in the South Indian Tamilian population. Eur J Clin Pharmacol (2012) 1.05
Pharmacogenetics and cardiovascular disease--implications for personalized medicine. Pharmacol Rev (2013) 1.04
Cardiovascular pharmacogenomics. Circ Res (2011) 1.03
Risk of adverse clinical outcomes with concomitant use of clopidogrel and proton pump inhibitors following percutaneous coronary intervention. Dig Dis Sci (2010) 0.94
Clinical pharmacokinetics of clopidogrel and its metabolites in patients with cardiovascular diseases. Clin Pharmacokinet (2014) 0.94
Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. Br J Pharmacol (2010) 0.90
Ticagrelor versus genotype-driven antiplatelet therapy for secondary prevention after acute coronary syndrome: a cost-effectiveness analysis. Value Health (2011) 0.88
Variability in response to clopidogrel: how important are pharmacogenetics and drug interactions? Br J Clin Pharmacol (2011) 0.87
Determinants to optimize response to clopidogrel in acute coronary syndrome. Pharmgenomics Pers Med (2010) 0.87
Risk assessment of mechanism-based inactivation in drug-drug interactions. Drug Metab Dispos (2012) 0.87
The drug-drug interaction between proton pump inhibitors and clopidogrel. CMAJ (2009) 0.86
Clopidogrel: a pharmacogenomic perspective on its use in coronary artery disease. Clin Med Insights Cardiol (2010) 0.85
Implementing genotype-guided antithrombotic therapy. Future Cardiol (2010) 0.85
Pharmacokinetics and pharmacodynamics following maintenance doses of prasugrel and clopidogrel in Chinese carriers of CYP2C19 variants. Br J Clin Pharmacol (2012) 0.84
Genetic testing for CYP450 polymorphisms to predict response to clopidogrel: current evidence and test availability. Application: pharmacogenomics. PLoS Curr (2010) 0.84
Pharmacogenomics of anti-platelet therapy: how much evidence is enough for clinical implementation? J Hum Genet (2013) 0.83
Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation. Pharmacogenomics (2012) 0.83
In vivo quantitative prediction of the effect of gene polymorphisms and drug interactions on drug exposure for CYP2C19 substrates. AAPS J (2013) 0.82
Cardiovascular and gastrointestinal events of three antiplatelet therapies: clopidogrel, clopidogrel plus proton-pump inhibitors, and aspirin plus proton-pump inhibitors in patients with previous gastrointestinal bleeding. J Gastroenterol (2010) 0.82
Implementation of Cell Samples as Controls in National Proficiency Testing for Clopidogrel Therapy-Related CYP2C19 Genotyping in China: A Novel Approach. PLoS One (2015) 0.81
Frequency of CYP3A4, CYP3A5, CYP2C9, and CYP2C19 variant alleles in patients receiving clopidogrel that experience repeat acute coronary syndrome. Heart Vessels (2009) 0.81
Pharmacogenomics of anti-platelet and anti-coagulation therapy. Curr Cardiol Rep (2013) 0.81
The influence of CYP 2C19*2 polymorphism on platelet function testing during single antiplatelet treatment with clopidogrel. Thromb J (2011) 0.81
Effect of ABCG2 genotypes on the pharmacokinetics of A771726, an active metabolite of prodrug leflunomide, and association of A771726 exposure with serum uric acid level. Eur J Clin Pharmacol (2010) 0.81
Association of CYP2C19 Polymorphisms with the Clinical Efficacy of Clopidogrel Therapy in Patients Undergoing Carotid Artery Stenting in Asia. Sci Rep (2016) 0.80
The pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19. Expert Opin Drug Metab Toxicol (2015) 0.79
Personalized vascular medicine: individualizing drug therapy. Vasc Med (2011) 0.79
Personalized antiplatelet and anticoagulation therapy: applications and significance of pharmacogenomics. Pharmgenomics Pers Med (2015) 0.79
Clinical evidence of interaction between clopidogrel and proton pump inhibitors. World J Cardiol (2011) 0.79
Applied pharmacogenomics in cardiovascular medicine. Annu Rev Med (2013) 0.78
Increased risk for developing major adverse cardiovascular events in stented Chinese patients treated with dual antiplatelet therapy after concomitant use of the proton pump inhibitor. PLoS One (2014) 0.78
Emerging therapies for acute coronary syndromes. Front Pharmacol (2011) 0.78
Exome sequencing of extreme clopidogrel response phenotypes identifies B4GALT2 as a determinant of on-treatment platelet reactivity. Clin Pharmacol Ther (2016) 0.78
CYP2C19 metabolizer status and clopidogrel efficacy in the Secondary Prevention of Small Subcortical Strokes (SPS3) study. J Am Heart Assoc (2015) 0.77
Drug-drug interaction of rabeprazole and clopidogrel in healthy Chinese volunteers. Eur J Clin Pharmacol (2012) 0.77
The effect of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of cilostazol and its active metabolites in healthy Korean subjects. Br J Clin Pharmacol (2014) 0.77
The interaction between clopidogrel and proton pump inhibitors (PPI): is there any clinical relevance? Clin Pharmacol (2010) 0.77
Expression of miRNA-26a in platelets is associated with clopidogrel resistance following coronary stenting. Exp Ther Med (2016) 0.76
Challenges in pharmacogenetics. Eur J Clin Pharmacol (2013) 0.76
Implications of Inter-Individual Differences in Clopidogrel Metabolism, with Focus on Pharmacogenetics. Pharmaceuticals (Basel) (2010) 0.75
Early dual antiplatelet therapy in stroke: should we take the CHANCE? Ann Transl Med (2015) 0.75
The P2Y(12) receptor as a target of antithrombotic drugs. Purinergic Signal (2011) 0.75
The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs. Dis Markers (2015) 0.75
Behind the paper: stepping up to the antiplatelet. Nat Med (2011) 0.75
Functions of cell surface heparan sulfate proteoglycans. Annu Rev Biochem (1999) 11.87
Fibroblast-mediated acceleration of human epithelial tumor growth in vivo. Proc Natl Acad Sci U S A (1990) 2.34
Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase. J Cell Biol (2000) 2.33
Fertility-sparing laparoscopic radical trachelectomy for young women with early stage cervical cancer. BJOG (2009) 2.33
Higher operating tables provide better laryngeal views for tracheal intubation. Br J Anaesth (2013) 2.13
Hydrocortisone enhances allergen-specific IgE production by peripheral blood mononuclear cells from atopic patients with high serum allergen-specific IgE levels. Clin Exp Allergy (2000) 2.07
International consensus on (ICON) pediatric asthma. Allergy (2012) 1.79
Trophic factors from pancreatic islets in combined hepatocyte-islet allografts enhance hepatocellular survival. Surgery (1989) 1.59
Measurement of the forward-backward charge asymmetry in top-quark pair production. Phys Rev Lett (2008) 1.53
Overexpression of p16INK4A and p14ARF in haematological malignancies. Clin Lab Haematol (2003) 1.45
A nationwide survey of naturally produced oysters for infection with Gymnophalloides seoi metacercariae. Korean J Parasitol (1996) 1.40
Prevalence and clinical characteristics of metabolic syndrome in a rural population of South Korea. Diabet Med (2004) 1.37
A case of spontaneous pneumomediastinum and pneumopericardium in a young adult. Korean J Intern Med (2001) 1.30
Comparison of fatty acid profiles in the serum of patients with prostate cancer and benign prostatic hyperplasia. Clin Biochem (1999) 1.30
Two human cases of Thelazia callipaeda infection in Korea. Korean J Parasitol (1995) 1.28
Clonorchis sinensis: molecular cloning and characterization of 28-kDa glutathione S-transferase. Exp Parasitol (2001) 1.27
Identification of Stictodora lari (Heterophyidae) metacercariae encysted in the brackish water fish, Acanthogobius flavimanus. Kisaengchunghak Chapchi (1989) 1.26
Fatty liver is an independent risk factor for the development of Type 2 diabetes in Korean adults. Diabet Med (2008) 1.23
[A human case of tick bite by Ixodes nipponensis on the scalp]. Kisaengchunghak Chapchi (1989) 1.23
Monolignol ferulate transferase introduces chemically labile linkages into the lignin backbone. Science (2014) 1.22
Change in prevalence and 6-year incidence of diabetes and impaired fasting glucose in Korean subjects living in a rural area. Diabetes Res Clin Pract (2007) 1.20
Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats. Diabetologia (2005) 1.19
Assessment of CYP2C19 genetic polymorphisms in a Korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19*2, CYP2C19*3, and CYP2C19*17 alleles. J Clin Pharm Ther (2010) 1.15
Outbreaks and diagnosis of foot-and-mouth disease serotype O in the Republic of Korea, April-June 2010. Transbound Emerg Dis (2012) 1.14
Angiolipoma of the duodenum diagnosed after endoscopic resection. Endoscopy (2004) 1.11
Intestinal trematode infections in the villagers in Koje-myon, Kochang-gun, Kyongsangnam-do, Korea. Korean J Parasitol (1994) 1.11
Through-the-scope double colonic stenting in the management of inoperable proximal malignant colonic obstruction: a pilot study. Endoscopy (2004) 1.10
Magnification rate of digital panoramic radiographs and its effectiveness for pre-operative assessment of dental implants. Dentomaxillofac Radiol (2011) 1.10
Laparoscopic versus open radical hysterectomy in early-stage cervical cancer: long-term survival outcomes in a matched cohort study. Ann Oncol (2011) 1.09
Inflammatory myofibroblastic tumor of the stomach with peritoneal dissemination in a young adult: imaging findings. Abdom Imaging (2004) 1.08
Molecular evidence of natural hybridization between Fasciola hepatica and F. gigantica. Parasitol Int (2000) 1.08
Congenital cholesteatoma of mastoid origin. J Laryngol Otol (2007) 1.07
Development of microsatellite markers for the kelp grouper Epinephelus bruneus by 454 pyrosequencing and transfer to related species. Genet Mol Res (2013) 1.07
Surface ultrastructure of Heterophyes nocens (Trematoda: Heterophyidae). Kisaengchunghak Chapchi (1992) 1.07
Toxic effects of mitomycin-C on cultured corneal keratocytes and endothelial cells. J Ocul Pharmacol Ther (1999) 1.07
Phenylephrine-induced Ca2+ oscillations in canine pulmonary artery smooth muscle cells. Circ Res (1997) 1.06
Search for large extra dimensions via single photon plus missing energy final states at sqrt s = 1.96 TeV. Phys Rev Lett (2008) 1.04
Inhibition of protein synthesis by nitric oxide correlates with cytostatic activity: nitric oxide induces phosphorylation of initiation factor eIF-2 alpha. Mol Med (1998) 1.03
The mitogenic effects of the B beta chain of fibrinogen are mediated through cell surface calreticulin. J Biol Chem (1995) 1.03
Prevalence of atopy and allergic diseases in Korean children: associations with a farming environment and rural lifestyle. Int Arch Allergy Immunol (2012) 1.02
Mechanisms of the inhibition by neostigmine of tetanic contraction in the mouse diaphragm. Br J Pharmacol (1986) 1.02
ABCG2 polymorphisms, 34G>A and 421C>A in a Korean population: analysis and a comprehensive comparison with other populations. J Clin Pharm Ther (2010) 1.01
Characterization of a putative clone for the 67-kilodalton elastin/laminin receptor suggests that it encodes a cytoplasmic protein rather than a cell surface receptor. Biochemistry (1991) 1.01
Ligand release-independent transactivation of epidermal growth factor receptor by transforming growth factor-beta involves multiple signaling pathways. Oncogene (2007) 1.01
Enthalpy recovery of a glass-forming liquid constrained in a nanoporous matrix: negative pressure effects. Eur Phys J E Soft Matter (2002) 1.00
Inhibition of VEGF blocks TGF-beta1 production through a PI3K/Akt signalling pathway. Eur Respir J (2007) 0.99
High-resolution impedance manometry facilitates assessment of pharyngeal residue and oropharyngeal dysphagic mechanisms. Dis Esophagus (2013) 0.98
Rapid identification and differentiation of Fasciola hepatica and Fasciola gigantica by a loop-mediated isothermal amplification (LAMP) assay. Vet Parasitol (2010) 0.98
A case of chronic cerebral paragonimiasis westermani. Korean J Parasitol (2000) 0.97
Expression of transgenes in midbrain dopamine neurons using the tyrosine hydroxylase promoter. Gene Ther (2008) 0.96
Electrical nanoprobing of semiconducting carbon nanotubes using an atomic force microscope. Phys Rev Lett (2004) 0.96
Magnetic resonance imaging in hemospermia. J Urol (1997) 0.95
Management of malignant stricture of the esophagogastric junction with a newly designed self-expanding metal stent with an antireflux mechanism. Endoscopy (2005) 0.95
Effectiveness and safety of varenicline as an aid to smoking cessation: results of an inter-Asian observational study in real-world clinical practice. Int J Clin Pract (2013) 0.94
Dissociation of the end-plate potential run-down and the tetanic fade from the postsynaptic inhibition of acetylcholine receptor by alpha-neurotoxins. Exp Neurol (1987) 0.94
Polyclonal antibodies to tropoelastin and the specific detection and measurement of tropoelastin in vitro. Connect Tissue Res (1991) 0.94
Search for flavor-changing-neutral-current d meson decays. Phys Rev Lett (2008) 0.94
Video-assisted thoracic surgery as a primary therapy for primary spontaneous pneumothorax. Decision making by the guideline of high-resolution computed tomography. Surg Endosc (1998) 0.93
Effect of active smoking on asthma symptoms, pulmonary function, and BHR in adolescents. Pediatr Pulmonol (2009) 0.93
Assessment of the fatty liver index as an indicator of hepatic steatosis for predicting incident diabetes independently of insulin resistance in a Korean population. Diabet Med (2013) 0.93
Quantitative histopathologic findings of erythromelanosis follicularis faciei et colli. J Cutan Pathol (2001) 0.93
Expressions of human sodium iodide symporter mRNA in primary and metastatic papillary thyroid carcinomas. Thyroid (2000) 0.92
Measurement of the lifetime of the Bc+/- meson in the semileptonic decay channel. Phys Rev Lett (2009) 0.92
Acetylcholine hydrolysis during neuromuscular transmission in the synaptic cleft of skeletal muscle of mouse and chick. Neuropharmacology (1985) 0.92
Intestinal histopathology and in situ postures of Gymnophalloides seoi in experimentally infected mice. Korean J Parasitol (2001) 0.91
Surface ultrastructure of juvenile and adult stages of Centrocestus armatus. J Helminthol (1998) 0.91
The clinical course of respiratory tuberculosis in lung cancer patients. Int J Tuberc Lung Dis (2009) 0.91
Management of malignant strictures of the cervical esophagus with a newly-designed self-expanding metal stent. Endoscopy (2004) 0.91
Measurement of the forward-backward charge asymmetry and extraction of sin2thetaWeff in pp-->Z/gamma* + X-->e+e- +X events produced at sqrt[s] = 1.96 TeV. Phys Rev Lett (2008) 0.91
Reversals of the neostigmine-induced tetanic fade and endplate potential run-down with respect to the autoregulation of transmitter release. Br J Pharmacol (1988) 0.91
Measurement of the inclusive jet cross section in pp[over] collisions at square root [s]=1.96 TeV. Phys Rev Lett (2008) 0.90
Endovenous laser ablation of the incompetent small saphenous vein with a 980-nm diode laser: our experience with 3 years follow-up. Eur J Vasc Endovasc Surg (2008) 0.90
Isolated left main coronary ostial stenosis in Oriental people: operative, histopathologic and clinical findings in six patients. J Am Coll Cardiol (1993) 0.89
SIGN-R1, a C-type lectin, enhances apoptotic cell clearance through the complement deposition pathway by interacting with C1q in the spleen. Cell Death Differ (2012) 0.89
Outcomes of colorectal anastomoses during pelvic exenteration for gynaecological malignancy. Br J Surg (2008) 0.89
A regenerating release of acetylcholine from mouse motor nerve terminals treated with anticholinesterase agents. Neurosci Lett (1986) 0.89
Regulation of the tyrosine hydroxylase and dopamine beta-hydroxylase genes by the transcription factor AP-2. J Neurochem (2001) 0.89
Reciprocal mesenchymal-epithelial interaction affecting prostate tumour growth and hormonal responsiveness. Cancer Surv (1991) 0.88
Chronic central administration of ghrelin reverses the effects of leptin. Int J Obes Relat Metab Disord (2004) 0.87
Novel E2F decoy oligodeoxynucleotides inhibit in vitro vascular smooth muscle cell proliferation and in vivo neointimal hyperplasia. Gene Ther (2002) 0.87
[Study on Centrocestus armatus in Korea. I. Infection status of Zacco platypus and Z. temminckii with the metacercariae of C. armatus]. Kisaengchunghak Chapchi (1989) 0.87
Prevalences of Gs alpha, ras, p53 mutations and ret/PTC rearrangement in differentiated thyroid tumours in a Korean population. Clin Endocrinol (Oxf) (1998) 0.87
Telomerase: a potential marker of bladder transitional cell carcinoma in bladder washes. Clin Cancer Res (1998) 0.86
Impact of cytochrome P450 3A and ATP-binding cassette subfamily B member 1 polymorphisms on tacrolimus dose-adjusted trough concentrations among Korean renal transplant recipients. Transplant Proc (2012) 0.86
Metabolic tumour volume and total lesion glycolysis, measured using preoperative 18F-FDG PET/CT, predict the recurrence of endometrial cancer. BJOG (2014) 0.86
Erythroplasia of Queyrat refractory to photodynamic therapy. Clin Exp Dermatol (2012) 0.85
A study on the membrane depolarization of skeletal muscles caused by a scorpion toxin, sea anemone toxin II and crotamine and the interaction between toxins. Br J Pharmacol (1983) 0.85
Cystadenocarcinoma of the ovary in a 4-year-old: benign transformation during therapy. Cancer (1980) 0.85
Progression to insulin deficiency in Korean patients with Type 2 diabetes mellitus positive for anti-GAD antibody. Diabet Med (2011) 0.84
A new 180 kDa. urine protein marker associated with bladder cancer. J Urol (1990) 0.84
Association of chronic hepatitis C virus infection and diabetes mellitus in Korean patients. Korean J Intern Med (2001) 0.84
Regulation of tyrosine hydroxylase gene transcription by the cAMP-signaling pathway: involvement of multiple transcription factors. Mol Cell Biochem (2000) 0.84
Microsatellite analysis as a tool for discriminating an interfamily hybrid between olive flounder and starry flounder. Genet Mol Res (2011) 0.84
Neuromuscular block by verapamil and diltiazem and inhibition of acetylcholine release. Brain Res (1988) 0.84
Search for Randall-Sundrum gravitons with 1 fb(-1) of data from pp collisions at sqrt(s)=1.96 TeV. Phys Rev Lett (2008) 0.84
Relative contributions of insulin resistance and β-cell dysfunction to the development of Type 2 diabetes in Koreans. Diabet Med (2013) 0.84
Cardiac tamponade due to a rupture of the coronary arteriovenous aneurysm--a case report. J Korean Med Sci (1997) 0.84
Cervical spine involvement in longstanding ankylosing spondylitis. Clin Exp Rheumatol (2005) 0.83
Long-term outcome of tamsulosin for patients with lower urinary tract symptoms according to the treatment response defined by lower urinary tract symptom outcomes score. Int J Clin Pract (2011) 0.83