Published in J Biol Chem on March 06, 2008
The Concise Guide to PHARMACOLOGY 2013/14: ion channels. Br J Pharmacol (2013) 3.03
ENaC structure and function in the wake of a resolved structure of a family member. Am J Physiol Renal Physiol (2011) 1.44
The epithelial sodium channel mediates the directionality of galvanotaxis in human keratinocytes. J Cell Sci (2013) 1.01
δ ENaC: a novel divergent amiloride-inhibitable sodium channel. Am J Physiol Lung Cell Mol Physiol (2012) 0.98
The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation. J Biol Chem (2009) 0.92
ENaCs and ASICs as therapeutic targets. Am J Physiol Cell Physiol (2012) 0.91
Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline. J Biol Chem (2012) 0.90
Cpt-cAMP activates human epithelial sodium channels via relieving self-inhibition. Biochim Biophys Acta (2011) 0.87
8-pCPT-cGMP stimulates alphabetagamma-ENaC activity in oocytes as an external ligand requiring specific nucleotide moieties. Am J Physiol Renal Physiol (2009) 0.87
Mechanism of action of novel lung edema therapeutic AP301 by activation of the epithelial sodium channel. Mol Pharmacol (2013) 0.85
Effect of ENaC modulators on rat neural responses to NaCl. PLoS One (2014) 0.82
Selective activation of hTRPV1 by N-geranyl cyclopropylcarboxamide, an amiloride-insensitive salt taste enhancer. PLoS One (2014) 0.81
8-(4-chlorophenylthio)-guanosine-3',5'-cyclic monophosphate-Na stimulates human alveolar fluid clearance by releasing external Na+ self-inhibition of epithelial Na+ channels. Am J Respir Cell Mol Biol (2011) 0.81
Ion channels in renal disease. Chem Rev (2012) 0.79
Regulatory Effects of Ca2+ and H+ on the Rat Chorda Tympani Response to NaCl and KCl. Chem Senses (2015) 0.75
Benzimidazolones enhance the function of epithelial Na⁺ transport. Br J Pharmacol (2013) 0.75
Exploration of the Peptide Recognition of an Amiloride-sensitive FMRFamide Peptide-gated Sodium Channel. J Biol Chem (2016) 0.75
Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats. PLoS One (2017) 0.75
Global mapping of the yeast genetic interaction network. Science (2004) 21.34
Taverna: a tool for building and running workflows of services. Nucleic Acids Res (2006) 14.90
Taverna: a tool for the composition and enactment of bioinformatics workflows. Bioinformatics (2004) 13.46
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature (2007) 9.25
Human receptors for sweet and umami taste. Proc Natl Acad Sci U S A (2002) 5.91
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nat Biotechnol (2008) 4.55
myExperiment: a repository and social network for the sharing of bioinformatics workflows. Nucleic Acids Res (2010) 4.41
Cys-loop receptors: new twists and turns. Trends Neurosci (2004) 3.58
p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron (2005) 3.13
The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases. Nat Med (2009) 3.05
The Celera Discovery System. Nucleic Acids Res (2002) 2.95
Different functional roles of T1R subunits in the heteromeric taste receptors. Proc Natl Acad Sci U S A (2004) 2.85
A taste receptor required for the caffeine response in vivo. Curr Biol (2006) 2.51
Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals. Genome Res (2008) 2.46
Endoscopic sealing of pancreatic fistula by using N-butyl-2-cyanoacrylate. Gastrointest Endosc (2004) 2.43
Identification of protein complexes required for efficient sister chromatid cohesion. Mol Biol Cell (2004) 2.34
Elg1 forms an alternative RFC complex important for DNA replication and genome integrity. EMBO J (2003) 2.03
Ras induces mediator complex exchange on C/EBP beta. Mol Cell (2004) 1.98
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression. J Biol Chem (2001) 1.97
Is endometriosis associated with systemic subclinical inflammation? Gynecol Obstet Invest (2006) 1.94
Label-free assays on the BIND system. J Biomol Screen (2004) 1.92
A detrimental mitochondrial-nuclear interaction causes cytoplasmic male sterility in rice. Nat Genet (2013) 1.92
Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. Hum Mol Genet (2003) 1.84
Gene and alternative splicing annotation with AIR. Genome Res (2005) 1.55
Endoplasmic reticulum retention, degradation, and aggregation of olfactory G-protein coupled receptors. Traffic (2003) 1.54
Identification of ligands for two human bitter T2R receptors. Chem Senses (2004) 1.53
Molecular mechanism for the umami taste synergism. Proc Natl Acad Sci U S A (2008) 1.53
Plasmacytoid precursor dendritic cells facilitate allogeneic hematopoietic stem cell engraftment. J Exp Med (2005) 1.53
Cytokine-induced myeloid differentiation is dependent on activation of the MEK/ERK pathway. Leuk Res (2005) 1.51
Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway. J Biol Chem (2002) 1.50
Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance. Int J Cancer (2002) 1.50
Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia with parkinsonism. Arch Neurol (2005) 1.49
Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin. Neuron (2003) 1.48
Bitter taste receptors influence glucose homeostasis. PLoS One (2008) 1.44
Diethyl 3,3'-(phenyl-methyl-ene)bis-(1H-indole-2-carboxyl-ate). Acta Crystallogr Sect E Struct Rep Online (2012) 1.42
Light activation, adaptation, and cell survival functions of the Na+/Ca2+ exchanger CalX. Neuron (2005) 1.37
Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. Curr Biol (2007) 1.37
Identification and expansion of cancer stem cells in tumor tissues and peripheral blood derived from gastric adenocarcinoma patients. Cell Res (2011) 1.36
Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice. J Clin Invest (2011) 1.36
Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression. J Biol Chem (2004) 1.33
Molecular mechanism of the sweet taste enhancers. Proc Natl Acad Sci U S A (2010) 1.32
Lsh controls Hox gene silencing during development. Proc Natl Acad Sci U S A (2007) 1.31
Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding. Nat Chem Biol (2010) 1.29
Molecular evolutionary analysis of the influenza A(H1N1)pdm, May-September, 2009: temporal and spatial spreading profile of the viruses in Japan. PLoS One (2010) 1.28
Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domain. Genes Dev (2005) 1.28
Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells. PLoS One (2010) 1.27
Multi-platform analysis of microRNA expression measurements in RNA from fresh frozen and FFPE tissues. PLoS One (2013) 1.24
Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma. J Neurooncol (2009) 1.23
Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans. J Allergy Clin Immunol (2009) 1.23
Conjugated microporous polymers: design, synthesis and application. Chem Soc Rev (2013) 1.23
Cancer stem cell-related gene periostin: a novel prognostic marker for breast cancer. PLoS One (2012) 1.22
Interleukin-1B and interleukin-1 RN polymorphisms and gastric carcinoma risk: a meta-analysis. J Gastroenterol Hepatol (2010) 1.20
Lsh participates in DNA methylation and silencing of stem cell genes. Stem Cells (2009) 1.20
Dimethyl 3,3'-(phenyl-methyl-ene)bis-(1H-indole-2-carboxyl-ate). Acta Crystallogr Sect E Struct Rep Online (2013) 1.18
Systems biology approaches to new vaccine development. Curr Opin Immunol (2011) 1.17
Increased B cell survival and preferential activation of the memory compartment by a malaria polyclonal B cell activator. J Immunol (2006) 1.16
Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser. BMC Bioinformatics (2005) 1.13
GigaDB: announcing the GigaScience database. Gigascience (2012) 1.12
Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra. Mov Disord (2005) 1.11
Genome-wide analysis of gene expression in primate taste buds reveals links to diverse processes. PLoS One (2009) 1.11
Impact of global economic disparities on practices and outcomes of chronic peritoneal dialysis in children: insights from the International Pediatric Peritoneal Dialysis Network Registry. Perit Dial Int (2012) 1.10
Fluorescent, superparamagnetic nanospheres for drug storage, targeting, and imaging: a multifunctional nanocarrier system for cancer diagnosis and treatment. ACS Nano (2010) 1.09
Voltage-gated sodium channels in taste bud cells. BMC Neurosci (2009) 1.09
Stromal cell-derived factor-1 antagonizes slit/robo signaling in vivo. J Neurosci (2007) 1.08
Girdin protein: a new potential distant metastasis predictor of breast cancer. Med Oncol (2011) 1.07
Bone marrow transplantation temporarily improves pancreatic function in streptozotocin-induced diabetes: potential involvement of very small embryonic-like cells. Transplantation (2010) 1.07
Ethyl 8-chloro-1-cyclo-propyl-6,7-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxyl-ate. Acta Crystallogr Sect E Struct Rep Online (2011) 1.07
CD8α+ plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo. Blood (2010) 1.07
Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma. Cancer (2011) 1.07
X-ray repair cross-complementing group 1 (XRCC1) genetic polymorphisms and gastric cancer risk: A HuGE review and meta-analysis. Am J Epidemiol (2011) 1.06
EST pipeline system: detailed and automated EST data processing and mining. Genomics Proteomics Bioinformatics (2003) 1.06
Flt3-ligand treatment prevents diabetes in NOD mice. Diabetes (2004) 1.06
Damage-induced localized hypermutability. Cell Cycle (2011) 1.05
Science of composite tissue allotransplantation. Transplantation (2008) 1.05
Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis. J Clin Invest (2013) 1.03
Endoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expression. BMC Cell Biol (2004) 1.03
Vitamin D supplementation for depressive symptoms: a systematic review and meta-analysis of randomized controlled trials. Psychosom Med (2014) 1.02
A label-free optical technique for detecting small molecule interactions. Biosens Bioelectron (2002) 1.02
Receiver-operating characteristic analyses of body mass index, waist circumference and waist-to-hip ratio for obesity: Screening in young adults in central south of China. Clin Nutr (2006) 1.02
Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. Neurobiol Dis (2005) 1.02
Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles. Biomaterials (2012) 1.02
Optimization of medium for one-step fermentation of inulin extract from Jerusalem artichoke tubers using Paenibacillus polymyxa ZJ-9 to produce R,R-2,3-butanediol. Bioresour Technol (2010) 1.02
The detection and quantification of growth cone collapsing activities. Nat Protoc (2007) 1.01
Nuclear factor kappa B signaling initiates early differentiation of neural stem cells. Stem Cells (2012) 0.99
A controlled trial of Chinese herbal medicine for premenstrual syndrome. J Psychosom Obstet Gynaecol (2008) 0.99
Proteomics, pathway array and signaling network-based medicine in cancer. Cell Div (2009) 0.99
Relative expression of 1,25-dihydroxyvitamin D3 receptor, vitamin D 1 alpha-hydroxylase, vitamin D 24-hydroxylase, and vitamin D 25-hydroxylase in endometriosis and gynecologic cancers. Reprod Sci (2007) 0.98
Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5. Bioorg Med Chem Lett (2010) 0.98
[Chlamydia-like and coronavirus-like agents found in dead cases of atypical pneumonia by electron microscopy]. Zhonghua Yi Xue Za Zhi (2003) 0.98