Analyzing the functions of large glycoconjugates through the dissipative properties of their absorbed layers using the gel-forming mucin MUC5B as an example.

Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure. J Clin Invest (2014) 1.26

Shedding of the mucin-like flocculin Flo11p reveals a new aspect of fungal adhesion regulation. Curr Biol (2010) 1.16

Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways. Mucosal Immunol (2012) 1.10

Unfolding dynamics of the mucin SEA domain probed by force spectroscopy suggest that it acts as a cell-protective device. FEBS J (2013) 0.81

Interfacial interaction between transmembrane ocular mucins and adhesive polymers and dendrimers analyzed by surface plasmon resonance. Pharm Res (2012) 0.79

The innate immune properties of airway mucosal surfaces are regulated by dynamic interactions between mucins and interacting proteins: the mucin interactome. Mucosal Immunol (2016) 0.78

Cell patterning with mucin biopolymers. Biomacromolecules (2013) 0.76

A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia. Science (2012) 2.98

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. FASEB J (2009) 2.07

Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B. Biochem J (2002) 2.02

From mucins to mucus: toward a more coherent understanding of this essential barrier. Proc Am Thorac Soc (2004) 2.02

Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? Am J Physiol Lung Cell Mol Physiol (2008) 1.55

Unpacking a gel-forming mucin: a view of MUC5B organization after granular release. Am J Physiol Lung Cell Mol Physiol (2009) 1.52

Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces. J Immunol (2005) 1.38

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways. J Physiol (2008) 1.33

Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure. J Clin Invest (2014) 1.26

Mucins and their O-Glycans from human bronchial epithelial cell cultures. Am J Physiol Lung Cell Mol Physiol (2004) 1.20

Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment. J Immunol (2009) 1.17

Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus. J Biol Chem (2003) 1.14

Crystal structure of the biglycan dimer and evidence that dimerization is essential for folding and stability of class I small leucine-rich repeat proteoglycans. J Biol Chem (2006) 1.12

The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A. J Biol Chem (2005) 1.06

Concentrated solutions of salivary MUC5B mucin do not replicate the gel-forming properties of saliva. Biochem J (2002) 0.99

The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status. Sci Rep (2012) 0.98

Light and X-ray scattering show decorin to be a dimer in solution. J Biol Chem (2003) 0.97

Predicting the molecular shape of polysaccharides from dynamic interactions with water. Glycobiology (2002) 0.93

Mapping the protein domain structures of the respiratory mucins: a mucin proteome coverage study. J Proteome Res (2012) 0.90

Investigating the molecular basis for the virulence of Escherichia coli K5 by nuclear magnetic resonance analysis of the capsule polysaccharide. J Mol Microbiol Biotechnol (2009) 0.90

Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii. BMC Microbiol (2009) 0.88

Mass spectrometric analysis of mucin core proteins. Methods Mol Biol (2012) 0.87

Making More MUCS. Am J Respir Cell Mol Biol (2003) 0.85

Mucociliary interactions and mucus dynamics in ciliated human bronchial epithelial cell cultures. Am J Physiol Lung Cell Mol Physiol (2011) 0.85

Studying mucin secretion from human bronchial epithelial cell primary cultures. Methods Mol Biol (2012) 0.84

Partial characterisation of high-molecular weight glycoconjugates in the trail mucus of the freshwater pond snail Lymnaea stagnalis. Comp Biochem Physiol B Biochem Mol Biol (2004) 0.82

Interaction of mucus with freshly neutralised aluminium in freshwater. J Inorg Biochem (2002) 0.75