Published in J Biol Chem on March 17, 2006
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem (2009) 2.12
Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors. BMC Genomics (2007) 1.80
Decorin core protein (decoron) shape complements collagen fibril surface structure and mediates its binding. PLoS One (2009) 1.18
Human primary corneal fibroblasts synthesize and deposit proteoglycans in long-term 3-D cultures. Dev Dyn (2008) 1.08
The crystal structure of the tumor suppressor protein pp32 (Anp32a): structural insights into Anp32 family of proteins. Protein Sci (2007) 0.97
The injury response of aged tendons in the absence of biglycan and decorin. Matrix Biol (2013) 0.96
FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development. Neuron (2014) 0.92
LRRCE: a leucine-rich repeat cysteine capping motif unique to the chordate lineage. BMC Genomics (2008) 0.89
Proteoglycan and collagen expression during human air conducting system development. Eur J Histochem (2012) 0.88
ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro. J Histochem Cytochem (2013) 0.85
Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase. J Biol Chem (2016) 0.83
The concave face of decorin mediates reversible dimerization and collagen binding. J Biol Chem (2013) 0.78
Proteoglycans and their heterogeneous glycosaminoglycans at the atomic scale. Biomacromolecules (2015) 0.78
Synthetic covalently linked dimeric form of H2 relaxin retains native RXFP1 activity and has improved in vitro serum stability. Biomed Res Int (2015) 0.77
Atomic force microscopy and transmission electron microscopy analyses of low-temperature laser welding of the cornea. Lasers Med Sci (2008) 0.77
Topological analysis of small leucine-rich repeat proteoglycan nyctalopin. PLoS One (2012) 0.76
Absence of the dermatan sulfate chain of decorin does not affect mouse development. J Negat Results Biomed (2017) 0.75
Detection of coronary atherosclerotic plaques with superficial proteoglycans and foam cells using real-time intrinsic fluorescence spectroscopy. Atherosclerosis (2010) 0.75
Grape seed extracts inhibit dentin matrix degradation by MMP-3. Front Physiol (2014) 0.75
The small leucine-rich repeat proteoglycans in tissue repair and atherosclerosis. J Intern Med (2015) 0.75
Purification, crystallization and preliminary X-ray diffraction analysis of human chondroadherin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.75
Comparative Geometrical Analysis of Leucine-Rich Repeat Structures in the Nod-Like and Toll-Like Receptors in Vertebrate Innate Immunity. Biomolecules (2015) 0.75
Decorin inhibits the proliferation of HepG2 cells by elevating the expression of transforming growth factor-β receptor II. Exp Ther Med (2016) 0.75
Biglycan Inhibits Capsaicin-Induced Substance P Release by Cultured Dorsal Root Ganglion Neurons. Am J Phys Med Rehabil (2016) 0.75
Small leucine-rich repeat proteoglycans in corneal inflammation and wound healing. Exp Eye Res (2016) 0.75
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia. Science (2012) 2.98
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. FASEB J (2009) 2.07
Vision impairment and dual sensory problems in middle age. Ophthalmic Physiol Opt (2014) 2.04
Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B. Biochem J (2002) 2.02
From mucins to mucus: toward a more coherent understanding of this essential barrier. Proc Am Thorac Soc (2004) 2.02
Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan. Proc Natl Acad Sci U S A (2004) 1.81
Structural correlations in the family of small leucine-rich repeat proteins and proteoglycans. J Struct Biol (2006) 1.66
Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? Am J Physiol Lung Cell Mol Physiol (2008) 1.55
Unpacking a gel-forming mucin: a view of MUC5B organization after granular release. Am J Physiol Lung Cell Mol Physiol (2009) 1.52
Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces. J Immunol (2005) 1.38
Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina. J Biol Chem (2010) 1.36
Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways. J Physiol (2008) 1.33
Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure. J Clin Invest (2014) 1.26
Mucins and their O-Glycans from human bronchial epithelial cell cultures. Am J Physiol Lung Cell Mol Physiol (2004) 1.20
Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3. Hum Mol Genet (2012) 1.18
Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis. Am J Pathol (2005) 1.14
Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus. J Biol Chem (2003) 1.14
Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA). Genome Med (2012) 1.11
Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions. J Immunol (2013) 1.06
The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A. J Biol Chem (2005) 1.06
Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology. Biochem Soc Trans (2010) 1.05
Missense and nonsense mutations in the alternatively-spliced exon 2 of COL2A1 cause the ocular variant of Stickler syndrome. Hum Mutat (2008) 1.04
Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia. Hum Mutat (2007) 1.03
Discovery and functional analysis of a retinitis pigmentosa gene, C2ORF71. Am J Hum Genet (2010) 1.03
Species specific membrane anchoring of nyctalopin, a small leucine-rich repeat protein. Hum Mol Genet (2005) 1.00
Concentrated solutions of salivary MUC5B mucin do not replicate the gel-forming properties of saliva. Biochem J (2002) 0.99
The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status. Sci Rep (2012) 0.98
Light and X-ray scattering show decorin to be a dimer in solution. J Biol Chem (2003) 0.97
Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration. Hum Mol Genet (2013) 0.97
The role of complement in age-related macular degeneration: heparan sulphate, a ZIP code for complement factor H? J Innate Immun (2013) 0.96
Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera. Invest Ophthalmol Vis Sci (2011) 0.96
No evidence of association between complement factor I genetic variant rs10033900 and age-related macular degeneration. Eur J Hum Genet (2011) 0.94
Characterization of opticin and evidence of stable dimerization in solution. J Biol Chem (2003) 0.93
Predicting the molecular shape of polysaccharides from dynamic interactions with water. Glycobiology (2002) 0.93
Opticin binds to heparan and chondroitin sulfate proteoglycans. Invest Ophthalmol Vis Sci (2005) 0.92
Age-dependent changes in the basal retinovitreous adhesion. Invest Ophthalmol Vis Sci (2003) 0.92
Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site. J Mol Biol (2005) 0.91
Mapping the protein domain structures of the respiratory mucins: a mucin proteome coverage study. J Proteome Res (2012) 0.90
Analyzing the functions of large glycoconjugates through the dissipative properties of their absorbed layers using the gel-forming mucin MUC5B as an example. Glycobiology (2008) 0.90
Investigating the molecular basis for the virulence of Escherichia coli K5 by nuclear magnetic resonance analysis of the capsule polysaccharide. J Mol Microbiol Biotechnol (2009) 0.90
Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2. Mol Vis (2011) 0.89
LRRCE: a leucine-rich repeat cysteine capping motif unique to the chordate lineage. BMC Genomics (2008) 0.89
Regulation of eye size by the retinal basement membrane and vitreous body. Invest Ophthalmol Vis Sci (2006) 0.88
Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii. BMC Microbiol (2009) 0.88
Mass spectrometric analysis of mucin core proteins. Methods Mol Biol (2012) 0.87
Iron, zinc, and copper in retinal physiology and disease. Surv Ophthalmol (2013) 0.87
The vitreous glycoprotein opticin inhibits preretinal neovascularization. Invest Ophthalmol Vis Sci (2012) 0.86
Making More MUCS. Am J Respir Cell Mol Biol (2003) 0.85
Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera. Invest Ophthalmol Vis Sci (2012) 0.85
Mucociliary interactions and mucus dynamics in ciliated human bronchial epithelial cell cultures. Am J Physiol Lung Cell Mol Physiol (2011) 0.85
The proteoglycan glycomatrix: a sugar microenvironment essential for complement regulation. Front Immunol (2013) 0.84
Studying mucin secretion from human bronchial epithelial cell primary cultures. Methods Mol Biol (2012) 0.84
Structural effects of fibulin 5 missense mutations associated with age-related macular degeneration and cutis laxa. Invest Ophthalmol Vis Sci (2009) 0.83
Opticin exerts its anti-angiogenic activity by regulating extracellular matrix adhesiveness. J Biol Chem (2012) 0.83
An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors. J Mol Biol (2006) 0.83
Fibulin 5 forms a compact dimer in physiological solutions. J Biol Chem (2009) 0.83
Biochemical and immunohistochemical studies of the protein expression and localization of decorin and biglycan in the temporomandibular joint disc of growing rats. Arch Oral Biol (2002) 0.82
Partial characterisation of high-molecular weight glycoconjugates in the trail mucus of the freshwater pond snail Lymnaea stagnalis. Comp Biochem Physiol B Biochem Mol Biol (2004) 0.82
De novo synthesis of human dermis in vitro in the absence of a three-dimensional scaffold. In Vitro Cell Dev Biol Anim (2009) 0.82
Repeatability of visual function measures in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol (2013) 0.80
Concentration of various trace elements in the rat retina and their distribution in different structures. Metallomics (2012) 0.80
Focus on molecules: opticin. Exp Eye Res (2006) 0.80
On the calculation of the binding force between decorin and collagen. J Biomech (2006) 0.79
Vitreous phenotype: genotype correlation in Stickler syndrome. Graefes Arch Clin Exp Ophthalmol (2002) 0.78
Neoplastic transformation of ciliary body epithelium is associated with loss of opticin expression. Br J Ophthalmol (2006) 0.77
Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells. Exp Hematol Oncol (2013) 0.77
The molecular structure of Rv1873, a conserved hypothetical protein from Mycobacterium tuberculosis, at 1.38 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.75
Interaction of mucus with freshly neutralised aluminium in freshwater. J Inorg Biochem (2002) 0.75