Stem cell sources and therapeutic approaches for central nervous system and neural retinal disorders.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 2647750)

Published in Neurosurg Focus on January 01, 2008

Authors

Diana Yu1, Gabriel A Silva

Author Affiliations

1: Department of Bioengineering, University of California, San Diego, USA.

Articles cited by this

(truncated to the top 100)

Embryonic stem cell lines derived from human blastocysts. Science (1998) 65.53

Core transcriptional regulatory circuitry in human embryonic stem cells. Cell (2005) 34.93

Establishment in culture of pluripotential cells from mouse embryos. Nature (1981) 30.49

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A (1993) 20.33

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A (1981) 18.96

Mammalian neural stem cells. Science (2000) 16.09

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell (2003) 13.47

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotechnol (2000) 12.41

Feeder-free growth of undifferentiated human embryonic stem cells. Nat Biotechnol (2001) 11.53

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol (1965) 9.18

Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol (2005) 9.12

In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol (2001) 9.04

Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci (2006) 8.09

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature (1988) 7.61

Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci U S A (2004) 7.51

Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature (2002) 7.28

Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat Med (2006) 7.21

Retinal repair by transplantation of photoreceptor precursors. Nature (2006) 6.73

From marrow to brain: expression of neuronal phenotypes in adult mice. Science (2000) 6.53

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature (2002) 6.51

Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods (2005) 6.37

Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science (2003) 6.35

Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest (2005) 5.90

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A (2000) 5.49

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci U S A (2004) 4.70

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev (1996) 4.61

Neural progenitors from human embryonic stem cells. Nat Biotechnol (2001) 4.48

Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat. Hum Mol Genet (2000) 4.42

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci U S A (2002) 4.20

The adult rat hippocampus contains primordial neural stem cells. Mol Cell Neurosci (1997) 4.07

Hematopoietic colony-forming cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2001) 4.07

Retinal stem cells in the adult mammalian eye. Science (2000) 3.97

Neural stem cells and neurospheres--re-evaluating the relationship. Nat Methods (2005) 3.92

Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell (1992) 3.82

Nuclear reprogramming and pluripotency. Nature (2006) 3.68

Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2002) 3.66

Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2000) 3.62

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol (2003) 3.43

Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells (2005) 3.38

Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J Neurosci (1996) 3.31

Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nat Biotechnol (1998) 3.28

Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci (1988) 3.13

Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol (2003) 3.09

Derivation of multipotent mesenchymal precursors from human embryonic stem cells. PLoS Med (2005) 3.04

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J Neurosci (1996) 3.04

Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: a long-term follow-up study. Lancet Neurol (2006) 2.99

Persistent production of neurons from adult brain stem cells during recovery after stroke. Stem Cells (2005) 2.88

Cell replacement therapies for central nervous system disorders. Nat Neurosci (2000) 2.84

Surface antigens of human embryonic stem cells: changes upon differentiation in culture. J Anat (2002) 2.52

Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens. Stem Cells (2002) 2.50

Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons. Nat Biotechnol (2002) 2.50

Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke. Stroke (2004) 2.49

Stem cell treatment in Amyotrophic Lateral Sclerosis. J Neurol Sci (2007) 2.48

Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology. Nat Methods (2006) 2.43

LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells. Stem Cells (2004) 2.37

Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics. Cloning Stem Cells (2004) 2.32

Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow. FASEB J (2004) 2.30

Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model. J Clin Invest (2005) 2.25

In vitro expansion of a multipotent population of human neural progenitor cells. Exp Neurol (1999) 2.24

Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats. Cloning Stem Cells (2006) 2.23

Cellular remodeling in mammalian retina: results from studies of experimental retinal detachment. Prog Retin Eye Res (2005) 2.21

Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex. Proc Natl Acad Sci U S A (1997) 2.20

Insulin production by human embryonic stem cells. Diabetes (2001) 2.20

Facile isolation and the characterization of human retinal stem cells. Proc Natl Acad Sci U S A (2004) 2.18

Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nat Biotechnol (1999) 2.18

Neuro-glial differentiation of human bone marrow stem cells in vitro. Exp Neurol (2005) 2.17

Neuronal diversity in the retina. Curr Opin Neurobiol (2001) 2.16

Induced neuronal differentiation of human embryonic stem cells. Brain Res (2001) 2.12

Transplantation of a novel cell line population of umbilical cord blood stem cells ameliorates neurological deficits associated with ischemic brain injury. Stem Cells Dev (2005) 2.07

Neural stem cell isolation and characterization. Methods Enzymol (2006) 2.03

Human mesenchymal stem cells: from basic biology to clinical applications. Gene Ther (2007) 2.00

Human feeder layers for human embryonic stem cells. Biol Reprod (2003) 1.94

Cell therapy in Parkinson's disease. NeuroRx (2004) 1.93

Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model. Mol Ther (2005) 1.91

In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons. J Neurochem (2005) 1.86

Plasticity of cultured mesenchymal stem cells: switch from nestin-positive to excitable neuron-like phenotype. Stem Cells (2005) 1.85

Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats. Transplantation (2006) 1.80

Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. J Neurobiol (1999) 1.79

Neuronal cell types. Curr Biol (2004) 1.77

Autoradiographic and histological studies of postnatal neurogenesis. I. A longitudinal investigation of the kinetics, migration and transformation of cells incorporating tritiated thymidine in neonate rats, with special reference to postnatal neurogenesis in some brain regions. J Comp Neurol (1966) 1.76

Remyelination of the rat spinal cord by transplantation of identified bone marrow stromal cells. J Neurosci (2002) 1.75

Maintenance of pluripotency in human embryonic stem cells is STAT3 independent. Stem Cells (2004) 1.73

GDNF delivery using human neural progenitor cells in a rat model of ALS. Hum Gene Ther (2005) 1.72

Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype. Proc Natl Acad Sci U S A (2006) 1.69

In vitro osteogenic differentiation of human ES cells. Cloning Stem Cells (2003) 1.67

Stem cell therapy in amyotrophic lateral sclerosis: a methodological approach in humans. Amyotroph Lateral Scler Other Motor Neuron Disord (2003) 1.67

Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. J Hematother Stem Cell Res (2003) 1.66

HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. Proc Natl Acad Sci U S A (2005) 1.65

Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease. Exp Neurol (2006) 1.64

Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol (1996) 1.64

Derivation of distal airway epithelium from human embryonic stem cells. Tissue Eng (2006) 1.60

Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia. Brain Res (2004) 1.55

Wild-type bone marrow cells ameliorate the phenotype of SOD1-G93A ALS mice and contribute to CNS, heart and skeletal muscle tissues. Brain (2004) 1.52

Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells. Biol Reprod (2005) 1.52

Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential. Prog Retin Eye Res (2004) 1.50

Retinal incorporation and differentiation of neural precursors derived from human embryonic stem cells. Stem Cells (2005) 1.45

Light at the end of the tunnel? Advances in the understanding and treatment of glaucoma and inherited retinal degeneration. Vet J (2007) 1.43

Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease. Stem Cells (2006) 1.43

Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model. PLoS One (2007) 1.41

Functional neuronal differentiation of bone marrow-derived mesenchymal stem cells. Stem Cells (2006) 1.41

Articles by these authors

The role of abnormal vitreomacular adhesion in age-related macular degeneration: spectral optical coherence tomography and surgical results. Am J Ophthalmol (2008) 2.10

In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase. J Neurosci (2013) 1.47

Characterization of the functional binding properties of antibody conjugated quantum dots. Nano Lett (2007) 1.16

Quantum dot applications to neuroscience: new tools for probing neurons and glia. J Neurosci (2006) 1.06

The challenge of connecting the dots in the B.R.A.I.N. Neuron (2013) 0.99

Diffusion modeling of ATP signaling suggests a partially regenerative mechanism underlies astrocyte intercellular calcium waves. Front Neuroeng (2008) 0.98

Amyloid β-peptide directly induces spontaneous calcium transients, delayed intercellular calcium waves and gliosis in rat cortical astrocytes. ASN Neuro (2010) 0.95

Toxicity and intraocular properties of a novel long-acting anti-proliferative and anti-angiogenic compound IMS2186. Curr Eye Res (2008) 0.92

Comparison of standard surface chemistries for culturing mesenchymal stem cells prior to neural differentiation. Biomaterials (2006) 0.87

Nanomedicine: seeing the benefits of ceria. Nat Nanotechnol (2006) 0.86

Characterization of Calcium-Mediated Intracellular and Intercellular Signaling in the rMC-1 Glial Cell Line. Cell Mol Bioeng (2009) 0.82

Nanomedicine: shorting neurons with nanotubes. Nat Nanotechnol (2009) 0.82

Direct inductive stimulation for energy-efficient wireless neural interfaces. Conf Proc IEEE Eng Med Biol Soc (2012) 0.80

Targeting the brain: advances in drug delivery. Curr Pharm Biotechnol (2012) 0.80

The effect of recombinant human hyaluronidase on dexamethasone penetration into the posterior segment of the eye after sub-Tenon's injection. J Ocul Pharmacol Ther (2006) 0.80

Multimodal analysis of PEI-mediated endocytosis of nanoparticles in neural cells. ACS Nano (2011) 0.79

Neuromodulation: selected approaches and challenges. J Neurochem (2012) 0.79

Ultra-high photosensitivity silicon nanophotonics for retinal prosthesis: electrical characteristics. Conf Proc IEEE Eng Med Biol Soc (2011) 0.79

Mapping the spatiotemporal dynamics of calcium signaling in cellular neural networks using optical flow. Ann Biomed Eng (2010) 0.79

A framework for simulating and estimating the state and functional topology of complex dynamic geometric networks. Neural Comput (2010) 0.78

Quantum dot labeling and imaging of glial fibrillary acidic protein intermediate filaments and gliosis in the rat neural retina and dissociated astrocytes. J Nanosci Nanotechnol (2009) 0.78

Automated detection of intercellular signaling in astrocyte networks using the converging squares algorithm. J Neurosci Methods (2008) 0.77

A positive feedback cell signaling nucleation model of astrocyte dynamics. Front Neuroeng (2013) 0.75

Testing of intraocular drugs for clinical use. Invest Ophthalmol Vis Sci (2007) 0.75

Bidirectional neural interface: Closed-loop feedback control for hybrid neural systems. Conf Proc IEEE Eng Med Biol Soc (2015) 0.75

Towards high-resolution retinal prostheses with direct optical addressing and inductive telemetry. J Neural Eng (2016) 0.75

Assembly and Calcium Binding Properties of Quantum Dot-Calmodulin Calcium Sensor. J Nanosci Nanotechnol (2016) 0.75

Visual evoked potential characterization of rabbit animal model for retinal prosthesis research. Conf Proc IEEE Eng Med Biol Soc (2013) 0.75