Stephen D Hursting

Author PubWeight™ 83.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Adult-onset calorie restriction and fasting delay spontaneous tumorigenesis in p53-deficient mice. Carcinogenesis 2002 1.52
2 Evaluating research training outcomes: experience from the cancer prevention fellowship program at the National Cancer Institute. Acad Med 2006 1.50
3 Environmental exposure, DNA methylation, and gene regulation: lessons from diethylstilbesterol-induced cancers. Ann N Y Acad Sci 2003 1.50
4 Obesity accelerates mouse mammary tumor growth in the absence of ovarian hormones. Nutr Cancer 2008 1.49
5 The growing challenge of obesity and cancer: an inflammatory issue. Ann N Y Acad Sci 2011 1.47
6 Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones. Endocrinology 2006 1.44
7 Dietary energy balance modulates signaling through the Akt/mammalian target of rapamycin pathways in multiple epithelial tissues. Cancer Prev Res (Phila) 2008 1.41
8 Associations between time spent sitting and cancer-related biomarkers in postmenopausal women: an exploration of effect modifiers. Cancer Causes Control 2014 1.37
9 Calorie restriction and diet composition modulate spontaneous intestinal tumorigenesis in Apc(Min) mice through different mechanisms. Cancer Res 2003 1.37
10 Physical activity and cancer prevention : pathways and targets for intervention. Sports Med 2008 1.24
11 Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival. Endocr Relat Cancer 2011 1.23
12 Adapting postdoctoral training to interdisciplinary science in the 21st century: the Cancer Prevention Fellowship Program at the National Cancer Institute. Acad Med 2005 1.22
13 Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models. Clin Cancer Res 2007 1.22
14 Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells. Int J Cancer 2008 1.19
15 Extreme obesity reduces bone mineral density: complementary evidence from mice and women. Obesity (Silver Spring) 2007 1.16
16 Inhibition of prostate cancer growth by muscadine grape skin extract and resveratrol through distinct mechanisms. Cancer Res 2007 1.14
17 The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001. Mol Carcinog 2012 1.12
18 Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity. Endocr Relat Cancer 2012 1.12
19 Intestinal microbiota: a potential diet-responsive prevention target in ApcMin mice. Mol Carcinog 2007 1.07
20 Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells. Endocr Relat Cancer 2013 1.06
21 Accelerated tumor formation in a fatless mouse with type 2 diabetes and inflammation. Cancer Res 2006 1.06
22 Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines. Cancer Epidemiol Biomarkers Prev 2005 1.03
23 Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line. Carcinogenesis 2006 1.03
24 Negative energy balance induced by voluntary wheel running inhibits polyp development in APCMin mice. Carcinogenesis 2006 1.03
25 Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer. Cancer Prev Res (Phila) 2011 1.01
26 Dietary energy balance modulates epithelial-to-mesenchymal transition and tumor progression in murine claudin-low and basal-like mammary tumor models. Cancer Prev Res (Phila) 2012 1.01
27 Race/ethnic variation in serum levels of IGF-I and IGFBP-3 in US adults. Growth Horm IGF Res 2008 1.01
28 Reduced susceptibility to two-stage skin carcinogenesis in mice with low circulating insulin-like growth factor I levels. Cancer Res 2008 1.00
29 Phenotypic effects of calorie restriction and insulin-like growth factor-1 treatment on body composition and bone mineral density of C57BL/6 mice: implications for cancer prevention. In Vivo 2005 0.99
30 Low-carbohydrate diet versus caloric restriction: effects on weight loss, hormones, and colon tumor growth in obese mice. Nutr Cancer 2008 0.99
31 Antitumor effects of ursolic acid in a mouse model of postmenopausal breast cancer. Nutr Cancer 2010 0.98
32 Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia. Cancer Prev Res (Phila) 2011 0.97
33 Differential effects of resveratrol on androgen-responsive LNCaP human prostate cancer cells in vitro and in vivo. Carcinogenesis 2008 0.95
34 C/EBPbeta regulates body composition, energy balance-related hormones and tumor growth. Carcinogenesis 2008 0.94
35 Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice. Mol Carcinog 2009 0.94
36 Combination of a poxvirus-based vaccine with a cyclooxygenase-2 inhibitor (celecoxib) elicits antitumor immunity and long-term survival in CEA.Tg/MIN mice. Cancer Res 2004 0.93
37 Effects of energy balance on cancer in genetically altered mice. J Nutr 2004 0.92
38 Exercise effects on tumorigenesis in a p53-deficient mouse model of breast cancer. Med Sci Sports Exerc 2009 0.91
39 Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1. Cancer Med 2012 0.91
40 Distinct effects of calorie restriction and exercise on mammary gland gene expression in C57BL/6 mice. Cancer Prev Res (Phila) 2009 0.90
41 Effect of intermittent fasting with or without caloric restriction on prostate cancer growth and survival in SCID mice. Prostate 2010 0.88
42 Metformin inhibits skin tumor promotion in overweight and obese mice. Cancer Prev Res (Phila) 2013 0.88
43 Carbohydrate versus energy restriction: effects on weight loss, body composition and metabolism. Ann Nutr Metab 2007 0.88
44 Differential effects of calorie restriction and exercise on the adipose transcriptome in diet-induced obese mice. J Obes 2011 0.88
45 P53 genotype as a determinant of ER expression and tamoxifen response in the MMTV-Wnt-1 model of mammary carcinogenesis. Breast Cancer Res Treat 2010 0.88
46 IGF1 dependence of dietary energy balance effects on murine Met1 mammary tumor progression, epithelial-to-mesenchymal transition, and chemokine expression. Endocr Relat Cancer 2013 0.88
47 Exercise and intestinal polyp development in APCMin mice. Med Sci Sports Exerc 2003 0.87
48 Energy balance modulates colon tumor growth: Interactive roles of insulin and estrogen. Mol Carcinog 2010 0.87
49 Using DNA microarray analyses to elucidate the effects of genistein in androgen-responsive prostate cancer cells: identification of novel targets. Mol Carcinog 2004 0.87
50 Energy balance modulates mouse skin tumor promotion through altered IGF-1R and EGFR crosstalk. Cancer Prev Res (Phila) 2012 0.87
51 Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion. Mol Carcinog 2008 0.87
52 Biodistribution and in vivo activities of tumor-associated macrophage-targeting nanoparticles incorporated with doxorubicin. Mol Pharm 2014 0.87
53 Effects of alcohol and menstrual cycle on insulin-like growth factor-I and insulin-like growth factor binding protein-3. Cancer Epidemiol Biomarkers Prev 2004 0.86
54 Concentration-dependent effects of genistein on global gene expression in MCF-7 breast cancer cells: an oligo microarray study. Breast Cancer Res Treat 2007 0.86
55 Interacting inflammatory and growth factor signals underlie the obesity-cancer link. J Nutr 2013 0.85
56 Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I. Cancer Prev Res (Phila) 2013 0.85
57 Obesity enhances nongenomic estrogen receptor crosstalk with the PI3K/Akt and MAPK pathways to promote in vitro measures of breast cancer progression. Breast Cancer Res 2013 0.85
58 Host factors and cancer outcome. J Clin Oncol 2010 0.85
59 Obesity, independent of p53 gene dosage, promotes mammary tumor progression and upregulates the p53 regulator microRNA-504. PLoS One 2013 0.84
60 Favorable modulation of benign breast tissue and serum risk biomarkers is associated with > 10 % weight loss in postmenopausal women. Breast Cancer Res Treat 2013 0.84
61 Effects of alcohol on insulin-like growth factor I and insulin-like growth factor binding protein 3 in postmenopausal women. Am J Clin Nutr 2005 0.84
62 Dietary calcium source influences body composition, glucose metabolism and hormone levels in a mouse model of postmenopausal obesity. In Vivo 2009 0.84
63 Genistein affects androgen-responsive genes through both androgen- and estrogen-induced signaling pathways. Mol Carcinog 2006 0.84
64 Relationship between plasma carotenoids and prostate cancer. Nutr Cancer 2005 0.84
65 Deconvoluting the obesity and breast cancer link: secretome, soil and seed interactions. J Mammary Gland Biol Neoplasia 2013 0.83
66 Decreased systemic IGF-1 in response to calorie restriction modulates murine tumor cell growth, nuclear factor-κB activation, and inflammation-related gene expression. Mol Carcinog 2012 0.83
67 Inhibition of androgen-responsive LNCaP prostate cancer cell tumor xenograft growth by dietary phenethyl isothiocyanate correlates with decreased angiogenesis and inhibition of cell attachment. Int J Oncol 2012 0.83
68 Leptin induces an Apc genotype-associated colon epithelial cell chemokine production pattern associated with macrophage chemotaxis and activation. Carcinogenesis 2006 0.82
69 Energy restriction and exercise differentially enhance components of systemic and mucosal immunity in mice. J Nutr 2008 0.82
70 Exercise enhances vaccine-induced antigen-specific T cell responses. Vaccine 2008 0.82
71 Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors. J Cancer Res Clin Oncol 2012 0.81
72 Effect of raloxifene on insulin-like growth factor-I, insulin-like growth factor binding protein-3, and leptin in premenopausal women at high risk for developing breast cancer. Cancer Epidemiol Biomarkers Prev 2003 0.81
73 Solid lipid nanoparticle formulations of docetaxel prepared with high melting point triglycerides: in vitro and in vivo evaluation. Mol Pharm 2014 0.80
74 Combination of physical activity, nutrition, or other metabolic factors and vaccine response. Front Biosci 2007 0.80
75 Obesity provides a permissive milieu in inflammation-associated carcinogenesis: analysis of insulin and IGF pathways. Methods Mol Biol 2009 0.80
76 Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells: a comparison study using DNA microarray. Mol Carcinog 2006 0.80
77 17beta-Estradiol differentially regulates androgen-responsive genes through estrogen receptor-beta- and extracellular-signal regulated kinase-dependent pathways in LNCaP human prostate cancer cells. Mol Carcinog 2007 0.80
78 Effects of the antiestrogen tamoxifen and the aromatase inhibitor letrozole on serum hormones and bone characteristics in a preclinical tumor model for breast cancer. Clin Cancer Res 2004 0.79
79 A weighty problem: metabolic perturbations and the obesity-cancer link. Horm Mol Biol Clin Investig 2015 0.78
80 Mechanistic targets and phytochemical strategies for breaking the obesity-cancer link. Front Oncol 2013 0.78
81 Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development. Transl Oncol 2009 0.77
82 Stearoyl gemcitabine nanoparticles overcome obesity-induced cancer cell resistance to gemcitabine in a mouse postmenopausal breast cancer model. Cancer Biol Ther 2013 0.77
83 The Translational Research Working Group developmental pathway for lifestyle alterations. Clin Cancer Res 2008 0.76
84 Obesity-associated systemic interleukin-6 promotes pre-adipocyte aromatase expression via increased breast cancer cell prostaglandin E2 production. Breast Cancer Res Treat 2014 0.76
85 Cancer risk from extreme stressors: lessons from European Jewish survivors of World War II. J Natl Cancer Inst 2009 0.76
86 The utility of genetically altered mouse models for cancer research. Mutat Res 2005 0.76
87 Bioavailable insulin-like growth factor-I inversely related to weight gain in postmenopausal women regardless of exogenous estrogen. Cancer Epidemiol Biomarkers Prev 2013 0.75