Published in Med Sci Sports Exerc on August 01, 2009
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Modulation of blood flow, hypoxia, and vascular function in orthotopic prostate tumors during exercise. J Natl Cancer Inst (2014) 1.02
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Physical activity and cancer prevention--mechanisms. Med Sci Sports Exerc (2003) 1.36
Exercise intensity dependent inhibition of 1-methyl-1-nitrosourea induced mammary carcinogenesis in female F-344 rats. Carcinogenesis (1995) 1.05
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Effects of dietary calorie restriction or exercise on the PI3K and Ras signaling pathways in the skin of mice. J Biol Chem (2007) 0.98
Weight control and breast cancer prevention: are the effects of reduced energy intake equivalent to those of increased energy expenditure? J Nutr (2004) 0.96
Exercise and tumor development in a mouse predisposed to multiple intestinal adenomas. Med Sci Sports Exerc (2000) 0.95
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The effect of exercise on systemic and bone concentrations of growth factors in rats. J Orthop Res (2001) 0.89
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Exercise and intestinal polyp development in APCMin mice. Med Sci Sports Exerc (2003) 0.87
Moderate exercise training slows mammary tumour growth in adolescent rats. Eur J Cancer Prev (2003) 0.87
Modulation of N-nitrosomethylurea induced mammary tumorigenesis by dietary fat and voluntary exercise. In Vivo (1992) 0.86
Different gene expression of skin tissues between mice with weight controlled by either calorie restriction or physical exercise. Exp Biol Med (Maywood) (2007) 0.85
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Physical activity in the United States measured by accelerometer. Med Sci Sports Exerc (2008) 38.10
p53 mutant mice that display early ageing-associated phenotypes. Nature (2002) 10.05
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol (2007) 5.48
Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice. Blood (2002) 4.88
Bethesda proposals for classification of lymphoid neoplasms in mice. Blood (2002) 4.07
Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium. Cancer Res (2004) 3.43
Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med (2001) 3.22
Assessing the value of team science: a study comparing center- and investigator-initiated grants. Am J Prev Med (2012) 3.00
Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res (2010) 2.99
PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints. Genes Dev (2005) 2.85
Sedentary activity associated with metabolic syndrome independent of physical activity. Diabetes Care (2011) 2.72
Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer. J Natl Cancer Inst (2005) 2.60
The National Collaborative on Childhood Obesity Research catalogue of surveillance systems and measures registry: new tools to spur innovation and increase productivity in childhood obesity research. Am J Prev Med (2012) 2.56
Levels and patterns of objectively assessed physical activity--a comparison between Sweden and the United States. Am J Epidemiol (2010) 2.35
The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop. Cancer Cell (2007) 2.32
Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2. Proc Natl Acad Sci U S A (2009) 2.28
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. J Natl Cancer Inst (2008) 2.25
Thermodynamics constrains the evolution of insect population growth rates: "warmer is better". Am Nat (2006) 2.23
Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation. Mol Cell Biol (2003) 2.22
Association of sedentary time with mortality independent of moderate to vigorous physical activity. PLoS One (2012) 2.21
Relationship between urban sprawl and weight of United States youth. Am J Prev Med (2006) 2.20
The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood (2006) 2.10
The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways. Cancer Metastasis Rev (2008) 2.06
Self-reported and objectively measured activity related to biomarkers using NHANES. Med Sci Sports Exerc (2011) 1.87
Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155. Nat Med (2011) 1.79
Physical activity in US youth: effect of race/ethnicity, age, gender, and weight status. Med Sci Sports Exerc (2010) 1.75
Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research. Carcinogenesis (2009) 1.72
Notch signaling contributes to the pathogenesis of human osteosarcomas. Hum Mol Genet (2009) 1.56
Prevalence of transportation and leisure walking among U.S. adults. Prev Med (2008) 1.53
Adult-onset calorie restriction and fasting delay spontaneous tumorigenesis in p53-deficient mice. Carcinogenesis (2002) 1.52
Employment and physical activity in the U.S. Am J Prev Med (2011) 1.51
Evaluating research training outcomes: experience from the cancer prevention fellowship program at the National Cancer Institute. Acad Med (2006) 1.50
Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1. Cancer Res (2005) 1.50
Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D. J Neurooncol (2007) 1.50
Environmental exposure, DNA methylation, and gene regulation: lessons from diethylstilbesterol-induced cancers. Ann N Y Acad Sci (2003) 1.50
Obesity accelerates mouse mammary tumor growth in the absence of ovarian hormones. Nutr Cancer (2008) 1.49
The growing challenge of obesity and cancer: an inflammatory issue. Ann N Y Acad Sci (2011) 1.47
Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control. Mol Cell Biol (2002) 1.46
Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. PLoS One (2010) 1.45
Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones. Endocrinology (2006) 1.44
Dietary energy balance modulates signaling through the Akt/mammalian target of rapamycin pathways in multiple epithelial tissues. Cancer Prev Res (Phila) (2008) 1.41
GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier. Proc Natl Acad Sci U S A (2011) 1.41
Associations between time spent sitting and cancer-related biomarkers in postmenopausal women: an exploration of effect modifiers. Cancer Causes Control (2014) 1.37
Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice. Mol Carcinog (2006) 1.37
Calorie restriction and diet composition modulate spontaneous intestinal tumorigenesis in Apc(Min) mice through different mechanisms. Cancer Res (2003) 1.37
The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair. Mol Cell (2004) 1.36
TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types. Cancer Cell (2012) 1.34
Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair. J Biol Chem (2010) 1.34
Reducing the weight of cancer: mechanistic targets for breaking the obesity-carcinogenesis link. Best Pract Res Clin Endocrinol Metab (2008) 1.32
MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression. Cancer Res (2009) 1.30
53BP1 oligomerization is independent of its methylation by PRMT1. Cell Cycle (2005) 1.29
Dietary intake estimates in the National Health Interview Survey, 2000: methodology, results, and interpretation. J Am Diet Assoc (2005) 1.29
Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control. Cell Cycle (2010) 1.27
Host-derived tumor endothelial marker 8 promotes the growth of melanoma. Cancer Res (2009) 1.27
Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34. Cancer Res (2007) 1.27
Transcriptional regulation of estrogen receptor-alpha by p53 in human breast cancer cells. Cancer Res (2009) 1.26
Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D. Cell Cycle (2005) 1.26
Energy balance and carcinogenesis: underlying pathways and targets for intervention. Curr Cancer Drug Targets (2007) 1.26
Loss of Rad51c leads to embryonic lethality and modulation of Trp53-dependent tumorigenesis in mice. Cancer Res (2009) 1.25
Physical activity and cancer prevention : pathways and targets for intervention. Sports Med (2008) 1.24
Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival. Endocr Relat Cancer (2011) 1.23
Adapting postdoctoral training to interdisciplinary science in the 21st century: the Cancer Prevention Fellowship Program at the National Cancer Institute. Acad Med (2005) 1.22
Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor. EMBO J (2006) 1.22
Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models. Clin Cancer Res (2007) 1.22
Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells. Int J Cancer (2008) 1.19
School-based nutrition programs produced a moderate increase in fruit and vegetable consumption: meta and pooling analyses from 7 studies. J Nutr Educ Behav (2007) 1.18
Extreme obesity reduces bone mineral density: complementary evidence from mice and women. Obesity (Silver Spring) (2007) 1.16
Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression. PLoS One (2009) 1.15
Inhibition of prostate cancer growth by muscadine grape skin extract and resveratrol through distinct mechanisms. Cancer Res (2007) 1.14
Probing p53 biological functions through the use of genetically engineered mouse models. Mutat Res (2005) 1.14
Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin. Dev Biol (2011) 1.13
The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001. Mol Carcinog (2012) 1.12
Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity. Endocr Relat Cancer (2012) 1.12
Strategic Priorities for Physical Activity Surveillance in the United States. Med Sci Sports Exerc (2016) 1.09
Insulin-like growth factors and subsequent risk of mortality in the United States. Am J Epidemiol (2007) 1.08
Intestinal microbiota: a potential diet-responsive prevention target in ApcMin mice. Mol Carcinog (2007) 1.07
Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis. Oncogene (2003) 1.07
Loss of heterozygosity occurs via mitotic recombination in Trp53+/- mice and associates with mammary tumor susceptibility of the BALB/c strain. Cancer Res (2004) 1.07
Association between neighborhood walkability, cardiorespiratory fitness and body-mass index. Soc Sci Med (2011) 1.06
Accelerated tumor formation in a fatless mouse with type 2 diabetes and inflammation. Cancer Res (2006) 1.06
Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells. Endocr Relat Cancer (2013) 1.06
Itch genetically interacts with Notch1 in a mouse autoimmune disease model. Hum Mol Genet (2006) 1.06