Published in Am J Respir Crit Care Med on March 20, 2008
Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol (2009) 2.31
BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis. Lancet Respir Med (2016) 1.51
Pathobiology of pulmonary arterial hypertension and right ventricular failure. Eur Respir J (2012) 1.39
Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects. Hum Mutat (2015) 1.38
Pulmonary arterial hypertension: an update. Neth Heart J (2011) 1.26
Truncating and missense BMPR2 mutations differentially affect the severity of heritable pulmonary arterial hypertension. Respir Res (2009) 1.24
Absence of influence of gender and BMPR2 mutation type on clinical phenotypes of pulmonary arterial hypertension. Respir Res (2010) 1.19
A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. Am J Physiol Lung Cell Mol Physiol (2012) 1.18
Pulmonary arterial hypertension. Orphanet J Rare Dis (2013) 1.18
The genetic basis of pulmonary arterial hypertension. Hum Genet (2014) 1.14
Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension. Nat Genet (2013) 1.11
Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension. Eur Respir J (2009) 1.11
Future perspectives for the treatment of pulmonary arterial hypertension. J Am Coll Cardiol (2009) 1.08
Novel loci interacting epistatically with bone morphogenetic protein receptor 2 cause familial pulmonary arterial hypertension. J Heart Lung Transplant (2009) 1.08
Genetics of pulmonary arterial hypertension. Semin Respir Crit Care Med (2009) 1.07
Hemodynamic and clinical onset in patients with hereditary pulmonary arterial hypertension and BMPR2 mutations. Respir Res (2011) 1.01
Correction of nonsense BMPR2 and SMAD9 mutations by ataluren in pulmonary arterial hypertension. Am J Respir Cell Mol Biol (2013) 0.96
The genetics of pulmonary arterial hypertension. Circ Res (2014) 0.95
Development of pulmonary arterial hypertension in women: interplay of sex hormones and pulmonary vascular disease. Womens Health (Lond Engl) (2010) 0.92
BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension. Am J Physiol Lung Cell Mol Physiol (2010) 0.89
Recent progress in understanding pediatric pulmonary hypertension. Curr Opin Pediatr (2011) 0.89
The genetics of pulmonary arterial hypertension in the post-BMPR2 era. Pulm Circ (2011) 0.87
Variations in CRHR1 are associated with persistent pulmonary hypertension of the newborn. Pediatr Res (2011) 0.87
Chronic allergic inflammation causes vascular remodeling and pulmonary hypertension in BMPR2 hypomorph and wild-type mice. PLoS One (2012) 0.85
Hemodynamic and genetic analysis in children with idiopathic, heritable, and congenital heart disease associated pulmonary arterial hypertension. Respir Res (2013) 0.85
Pulmonary arterial hypertension: insights from genetic studies. Proc Am Thorac Soc (2011) 0.84
Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle. Am J Respir Crit Care Med (2016) 0.83
Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene. PLoS One (2013) 0.82
A Functional Variant rs6435156C > T in BMPR2 is Associated With Increased Risk of Chronic Obstructive Pulmonary Disease (COPD) in Southern Chinese Population. EBioMedicine (2016) 0.81
Heritable forms of pulmonary arterial hypertension. Semin Respir Crit Care Med (2013) 0.81
Molecular pathogenesis and current pathology of pulmonary hypertension. Heart Fail Rev (2016) 0.80
BMPR2 mutation and outcome in pulmonary arterial hypertension: clinical relevance to physicians and patients. Am J Respir Crit Care Med (2008) 0.78
A host-guest relationship in bone morphogenetic protein receptor-II defines specificity in ligand-receptor recognition. Biochemistry (2012) 0.78
2014 Guidelines of Taiwan Society of Cardiology (TSOC) for the Management of Pulmonary Arterial Hypertension. Zhonghua Minguo Xin Zang Xue Hui Za Zhi (2014) 0.77
Programmatic change: lung disease research in the era of induced pluripotency. Am J Physiol Lung Cell Mol Physiol (2011) 0.77
Functional changes in pulmonary arterial endothelial cells associated with BMPR2 mutations. PLoS One (2014) 0.77
A novel BMPR2 mutation associated with pulmonary arterial hypertension in an octogenarian. Lung (2010) 0.77
Associated pulmonary arterial hypertension in connective tissue diseases. Maedica (Buchar) (2011) 0.76
Genetic counselling for pulmonary arterial hypertension: a matter of variable variability. Neth Heart J (2011) 0.75
The role of genetics in pulmonary arterial hypertension. J Pathol (2016) 0.75
Genotype-phenotype effects of Bmpr2 mutations on disease severity in mouse models of pulmonary hypertension. Pulm Circ (2016) 0.75
Kidney dysfunction in patients with pulmonary arterial hypertension. Pulm Circ (2017) 0.75
Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol (2009) 12.05
Bosentan therapy for pulmonary arterial hypertension. N Engl J Med (2002) 11.18
A hemodynamic study of pulmonary hypertension in sickle cell disease. N Engl J Med (2011) 7.21
Treatment of pulmonary arterial hypertension. N Engl J Med (2004) 6.88
2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J (2014) 6.32
Pulmonary arterial hypertension in France: results from a national registry. Am J Respir Crit Care Med (2006) 6.06
Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation (2010) 5.87
Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med (2013) 5.60
Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. N Engl J Med (2013) 5.22
Macitentan and morbidity and mortality in pulmonary arterial hypertension. N Engl J Med (2013) 4.98
Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. J Am Coll Cardiol (2002) 4.79
Inhaled iloprost for severe pulmonary hypertension. N Engl J Med (2002) 3.90
Inflammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol (2009) 3.75
Diagnosis and differential assessment of pulmonary arterial hypertension. J Am Coll Cardiol (2004) 3.63
Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology. Eur Heart J (2004) 3.51
Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med (2014) 3.50
Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study. Arthritis Rheum (2005) 3.44
Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med (2008) 3.13
Tadalafil therapy for pulmonary arterial hypertension. Circulation (2009) 2.98
Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation (2005) 2.98
Pathologic assessment of vasculopathies in pulmonary hypertension. J Am Coll Cardiol (2004) 2.93
Pulmonary arterial hypertension in patients treated by dasatinib. Circulation (2012) 2.87
Role of truncating mutations in MME gene in fetomaternal alloimmunisation and antenatal glomerulopathies. Lancet (2004) 2.82
Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines. Chest (2007) 2.67
Updated evidence-based treatment algorithm in pulmonary arterial hypertension. J Am Coll Cardiol (2009) 2.57
Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension. Am J Respir Crit Care Med (2012) 2.52
Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med (2008) 2.48
New formula for predicting mean pulmonary artery pressure using systolic pulmonary artery pressure. Chest (2004) 2.47
Is pulmonary arterial hypertension really a late complication of systemic sclerosis? Chest (2009) 2.40
Long-term outcome with first-line bosentan therapy in idiopathic pulmonary arterial hypertension. Eur Heart J (2006) 2.34
Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol (2009) 2.31
Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension. Hum Mutat (2006) 2.30
CX(3)C chemokine fractalkine in pulmonary arterial hypertension. Am J Respir Crit Care Med (2002) 2.15
C-kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med (2011) 2.12
T-helper 17 cell polarization in pulmonary arterial hypertension. Chest (2015) 2.09
Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest (2004) 2.00
Retrospective institutional study of 31 patients treated for pulmonary artery sarcoma. Eur J Cardiothorac Surg (2012) 1.97
Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension. Circ Res (2004) 1.92
Proinflammatory cytokine levels are linked to death in pulmonary arterial hypertension. Eur Respir J (2013) 1.92
Severe pulmonary hypertension during pregnancy: mode of delivery and anesthetic management of 15 consecutive cases. Anesthesiology (2005) 1.88
Severe asthma in adults: what are the important questions? J Allergy Clin Immunol (2007) 1.85
Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia. Circulation (2006) 1.79
Diagnosis, assessment, and treatment of non-pulmonary arterial hypertension pulmonary hypertension. J Am Coll Cardiol (2009) 1.78
Guidelines for splicing analysis in molecular diagnosis derived from a set of 327 combined in silico/in vitro studies on BRCA1 and BRCA2 variants. Hum Mutat (2012) 1.77
Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol (2002) 1.77
Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers. J Am Coll Cardiol (2006) 1.76
Survival and prognostic factors in systemic sclerosis-associated pulmonary hypertension: a systematic review and meta-analysis. Arthritis Rheum (2013) 1.73
Portopulmonary hypertension: survival and prognostic factors. Am J Respir Crit Care Med (2008) 1.71
BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension. Hum Mutat (2006) 1.69
Pulmonary Langerhans cell histiocytosis-associated pulmonary hypertension: clinical characteristics and impact of pulmonary arterial hypertension therapies. Chest (2012) 1.68
Surgical management and outcome of patients with chronic thromboembolic pulmonary hypertension: results from an international prospective registry. J Thorac Cardiovasc Surg (2011) 1.66
Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis. Circ Res (2008) 1.65
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. J Clin Invest (2009) 1.65
Pregnancy outcomes in pulmonary arterial hypertension in the modern management era. Eur Respir J (2012) 1.63
End points and clinical trial design in pulmonary arterial hypertension. J Am Coll Cardiol (2009) 1.63
Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and doppler measures in patients with pulmonary arterial hypertension. J Am Coll Cardiol (2003) 1.62
2015 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension. Rev Esp Cardiol (Engl Ed) (2016) 1.61
Intravenous epoprostenol in inoperable chronic thromboembolic pulmonary hypertension. J Heart Lung Transplant (2007) 1.58
The role of imaging techniques in the assessment of pulmonary circulation. J Bras Pneumol (2011) 1.58
Potts shunt in children with idiopathic pulmonary arterial hypertension: long-term results. Ann Thorac Surg (2012) 1.54