Published in Int J Dev Neurosci on February 15, 2008
Estrogen: a master regulator of bioenergetic systems in the brain and body. Front Neuroendocrinol (2013) 1.10
Increased regional cerebral glucose uptake in an APP/PS1 model of Alzheimer's disease. Neurobiol Aging (2011) 1.06
Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models. Brain Res (2010) 1.00
The role of glucose transporters in brain disease: diabetes and Alzheimer’s Disease. Int J Mol Sci (2012) 0.96
Early detection of cerebral glucose uptake changes in the 5XFAD mouse. Curr Alzheimer Res (2014) 0.81
In vivo molecular neuroimaging of glucose utilization and its association with fibrillar amyloid-β load in aged APPPS1-21 mice. Alzheimers Res Ther (2015) 0.80
In vivo imaging biomarkers in mouse models of Alzheimer's disease: are we lost in translation or breaking through? Int J Alzheimers Dis (2010) 0.78
Broad-based nutritional supplementation in 3xTg mice corrects mitochondrial function and indicates sex-specificity in response to Alzheimer's disease intervention. J Alzheimers Dis (2012) 0.77
A review of β-amyloid neuroimaging in Alzheimer's disease. Front Neurosci (2014) 0.77
Down-Regulated Drebrin Aggravates Cognitive Impairments in a Mouse Model of Alzheimer's Disease. Int J Mol Sci (2017) 0.75
Brain energy metabolism and neuroinflammation in ageing APP/PS1-21 mice using longitudinal 18F-FDG and 18F-DPA-714 PET imaging. J Cereb Blood Flow Metab (2016) 0.75
A default mode of brain function. Proc Natl Acad Sci U S A (2001) 50.73
Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N Engl J Med (1996) 10.60
Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Ann Neurol (1997) 10.06
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med (1998) 5.78
Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees. J Neurosci (2007) 3.91
A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease. Nature (2001) 3.28
Age-related differences in neural activity during memory encoding and retrieval: a positron emission tomography study. J Neurosci (1997) 2.85
Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664. Proc Natl Acad Sci U S A (2006) 2.45
Posterior cingulate cortex in Alzheimer's disease. Lancet (1994) 2.11
Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease. Neurobiol Aging (2005) 2.06
Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: superficial laminar cytochrome oxidase associated with disease duration. J Neurosci (2001) 1.88
The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo. J Neurosci (2003) 1.50
Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model. Proc Natl Acad Sci U S A (2003) 1.37
Tracking Alzheimer's disease in transgenic mice using fluorodeoxyglucose autoradiography. Neuroreport (2000) 1.31
Early regional cerebral glucose hypometabolism in transgenic mice overexpressing the V717F beta-amyloid precursor protein. Neurosci Lett (1999) 1.11
Network analysis of positron emission tomography regional cerebral blood flow data: ensemble inhibition during episodic memory retrieval. J Neurosci (1996) 1.07
Hippocampal control of cingulate cortical and anterior thalamic information processing during learning in rabbits. Exp Brain Res (1987) 1.04
Fos expression in the rostral thalamic nuclei and associated cortical regions in response to different spatial memory tests. Neuroscience (2000) 1.04
Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice. Brain Res (2006) 0.97
Reduced corpus callosum, fornix and hippocampus in PDAPP transgenic mouse model of Alzheimer's disease. Neuroreport (2001) 0.93
Nonprogressive transgene-related callosal and hippocampal changes in PDAPP mice. Neuroreport (2006) 0.88
Postnatal development of cytochrome oxidase activity in fiber tracts of the rat brain. Brain Res Dev Brain Res (1999) 0.80
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.02
A survey of genetic human cortical gene expression. Nat Genet (2007) 12.04
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J Clin Psychiatry (2007) 7.23
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect. N Engl J Med (2009) 4.45
Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI. Neurobiol Aging (2009) 3.97
Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies. Am J Hum Genet (2006) 3.67
Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study. Lancet Neurol (2012) 3.66
Genetic control of human brain transcript expression in Alzheimer disease. Am J Hum Genet (2009) 3.35
Common Kibra alleles are associated with human memory performance. Science (2006) 3.30
The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core. Alzheimers Dement (2010) 3.30
Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. Am J Psychiatry (2002) 3.20
Brain abnormalities in human obesity: a voxel-based morphometric study. Neuroimage (2006) 2.94
Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias. J Nucl Med (2008) 2.92
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
The role of biomarkers in clinical trials for Alzheimer disease. Alzheimer Dis Assoc Disord (2006) 2.86
Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease. Arch Neurol (2011) 2.81
Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Neuroimage (2009) 2.80
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science (2011) 2.66
Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study. Lancet Neurol (2012) 2.65
Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. Proc Natl Acad Sci U S A (2008) 2.59
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet (2010) 2.51
Antidepressant-like effects of medial prefrontal cortex deep brain stimulation in rats. Biol Psychiatry (2010) 2.36
Optimizing power to track brain degeneration in Alzheimer's disease and mild cognitive impairment with tensor-based morphometry: an ADNI study of 515 subjects. Neuroimage (2009) 2.28
Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study. Neurology (2012) 2.26
Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. Physiol Genomics (2008) 2.11
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol (2011) 2.02
Neural correlates of heart rate variability during emotion. Neuroimage (2008) 1.99
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics (2006) 1.88
Genetics, transcriptomics, and proteomics of Alzheimer's disease. J Clin Psychiatry (2006) 1.81
Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging. Alzheimers Dement (2013) 1.77
Imaging markers for Alzheimer disease: which vs how. Neurology (2013) 1.76
Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease. JAMA Neurol (2013) 1.75
Alzheimer's disease a century later. J Clin Psychiatry (2006) 1.74
Mapping Alzheimer's disease progression in 1309 MRI scans: power estimates for different inter-scan intervals. Neuroimage (2010) 1.69
Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates. Am J Psychiatry (2007) 1.68
Altered default mode network connectivity in Alzheimer's disease--a resting functional MRI and Bayesian network study. Hum Brain Mapp (2011) 1.67
Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment. Arch Neurol (2007) 1.61
Comparing 3 T and 1.5 T MRI for tracking Alzheimer's disease progression with tensor-based morphometry. Hum Brain Mapp (2010) 1.55
Characterizing Alzheimer's disease using a hypometabolic convergence index. Neuroimage (2011) 1.54
Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene. J Alzheimers Dis (2010) 1.54
A genome-wide association study of aging. Neurobiol Aging (2011) 1.54
A preliminary fluorodeoxyglucose positron emission tomography study in healthy adults reporting dream-enactment behavior. Sleep (2006) 1.54
Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease. Neurobiol Aging (2013) 1.53
Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease. Neurobiol Aging (2012) 1.49
Accurate measurement of brain changes in longitudinal MRI scans using tensor-based morphometry. Neuroimage (2011) 1.44
Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals. Neurobiol Aging (2012) 1.43
Association between trait emotional awareness and dorsal anterior cingulate activity during emotion is arousal-dependent. Neuroimage (2008) 1.31
Arithmetic processing in the brain shaped by cultures. Proc Natl Acad Sci U S A (2006) 1.31
Sorl1 as an Alzheimer's disease predisposition gene? Neurodegener Dis (2007) 1.31
Sensory experience of food and obesity: a positron emission tomography study of the brain regions affected by tasting a liquid meal after a prolonged fast. Neuroimage (2005) 1.28
Blood pressure is associated with higher brain amyloid burden and lower glucose metabolism in healthy late middle-age persons. Neurobiol Aging (2011) 1.27
Regional network of magnetic resonance imaging gray matter volume in healthy aging. Neuroreport (2006) 1.27
Less activation of the left dorsolateral prefrontal cortex in response to a meal: a feature of obesity. Am J Clin Nutr (2006) 1.27
A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging (2011) 1.27
Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment. Mitochondrion (2006) 1.25
The Alzheimer's prevention initiative composite cognitive test score: sample size estimates for the evaluation of preclinical Alzheimer's disease treatments in presenilin 1 E280A mutation carriers. J Clin Psychiatry (2014) 1.25
Sex differences in the human brain's response to hunger and satiation. Am J Clin Nutr (2002) 1.25
Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol (2013) 1.25
Gene expression correlates of neurofibrillary tangles in Alzheimer's disease. Neurobiol Aging (2005) 1.24
Evidence for an association between KIBRA and late-onset Alzheimer's disease. Neurobiol Aging (2008) 1.24
A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline. Hum Mol Genet (2012) 1.22
Cognitive performance in older women relative to ApoE-epsilon4 genotype and aerobic fitness. Med Sci Sports Exerc (2007) 1.22
Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment. Arch Neurol (2008) 1.21
Linking functional and structural brain images with multivariate network analyses: a novel application of the partial least square method. Neuroimage (2009) 1.17
Clinical and multimodal biomarker correlates of ADNI neuropathological findings. Acta Neuropathol Commun (2013) 1.15
Vicarious trial-and-error behavior and hippocampal cytochrome oxidase activity during Y-maze discrimination learning in the rat. Int J Neurosci (2006) 1.12
Relationships between plasma leptin concentrations and human brain structure: a voxel-based morphometric study. Neurosci Lett (2006) 1.12
Less activation in the left dorsolateral prefrontal cortex in the reanalysis of the response to a meal in obese than in lean women and its association with successful weight loss. Am J Clin Nutr (2007) 1.10
Quantitation of heteroplasmy of mtDNA sequence variants identified in a population of AD patients and controls by array-based resequencing. Mitochondrion (2006) 1.07
Apolipoprotein E and intellectual achievement. J Am Geriatr Soc (2002) 1.06
Postprandial glucagon-like peptide-1 (GLP-1) response is positively associated with changes in neuronal activity of brain areas implicated in satiety and food intake regulation in humans. Neuroimage (2007) 1.05
Large-scale directional connections among multi resting-state neural networks in human brain: a functional MRI and Bayesian network modeling study. Neuroimage (2011) 1.04
Ushering in the study and treatment of preclinical Alzheimer disease. Nat Rev Neurol (2013) 1.03
A distinctive interaction between memory and chronic daytime somnolence in asymptomatic APOE e4 homozygotes. Sleep (2002) 1.02
Summary metrics to assess Alzheimer disease-related hypometabolic pattern with 18F-FDG PET: head-to-head comparison. J Nucl Med (2012) 1.02
Attention-related networks in Alzheimer's disease: a resting functional MRI study. Hum Brain Mapp (2011) 1.02
Hypometabolism in Alzheimer-affected brain regions in cognitively healthy Latino individuals carrying the apolipoprotein E epsilon4 allele. Arch Neurol (2010) 1.02
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Ann Hum Genet (2013) 1.02
Longitudinal modeling of cognitive aging and the TOMM40 effect. Alzheimers Dement (2012) 1.01
Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition. Acta Neuropathol Commun (2014) 1.01
Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology. Neurobiol Aging (2008) 1.00
Gray matter network associated with risk for Alzheimer's disease in young to middle-aged adults. Neurobiol Aging (2012) 1.00
Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models. Brain Res (2010) 1.00
Peripheral delivery of a ROCK inhibitor improves learning and working memory. Behav Neurosci (2009) 1.00
Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions. Neurology (2013) 0.98
Low-level light therapy improves cortical metabolic capacity and memory retention. J Alzheimers Dis (2012) 0.98
Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice. Brain Res (2006) 0.97
A distinctive interaction between chronic anxiety and problem solving in asymptomatic APOE e4 homozygotes. J Neuropsychiatry Clin Neurosci (2004) 0.97
Characterizing the preclinical stages of Alzheimer's disease and the prospect of presymptomatic intervention. J Alzheimers Dis (2013) 0.95
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A (2012) 0.95
High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation. BMC Genomics (2010) 0.95
Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates. J Neuropathol Exp Neurol (2014) 0.94
Role of biomarkers in studies of presymptomatic Alzheimer's disease. Alzheimers Dement (2005) 0.94
Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers. J Neurol Neurosurg Psychiatry (2012) 0.93
Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance. Hum Mol Genet (2007) 0.93