Published in J Alzheimers Dis on January 01, 2012
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Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene. J Alzheimers Dis (2010) 1.54
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Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci (2003) 1.50
Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels. J Neurosci (2007) 1.47
Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice. Neurobiol Dis (2006) 1.45
Progesterone reverses the spatial memory enhancements initiated by tonic and cyclic oestrogen therapy in middle-aged ovariectomized female rats. Eur J Neurosci (2006) 1.44
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Tracking Alzheimer's disease in transgenic mice using fluorodeoxyglucose autoradiography. Neuroreport (2000) 1.31
Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment. Mitochondrion (2006) 1.25
Docosahexaenoic acid reduces amyloid beta production via multiple pleiotropic mechanisms. J Biol Chem (2011) 1.10
Sex differences in β-amyloid accumulation in 3xTg-AD mice: role of neonatal sex steroid hormone exposure. Brain Res (2010) 1.08
Medroxyprogesterone acetate impairs memory and alters the GABAergic system in aged surgically menopausal rats. Neurobiol Learn Mem (2010) 1.06
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Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models. PLoS One (2011) 1.01
Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models. Brain Res (2010) 1.00
DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice. PLoS One (2011) 0.98
Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice. Brain Res (2006) 0.97
Can nutrients prevent or delay onset of Alzheimer's disease? J Alzheimers Dis (2010) 0.94
Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease. PLoS One (2010) 0.93
FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice. Int J Dev Neurosci (2008) 0.87
Zyflamend in men with high-grade prostatic intraepithelial neoplasia: results of a phase I clinical trial. J Soc Integr Oncol (2009) 0.86
Dietary supplementation with S-adenosyl methionine delayed amyloid-β and tau pathology in 3xTg-AD mice. J Alzheimers Dis (2012) 0.82
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J Clin Psychiatry (2007) 7.23
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science (2004) 4.81
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Increased islet apoptosis in Pdx1+/- mice. J Clin Invest (2003) 2.91
Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders. Acta Neuropathol (2010) 2.73
Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction. Acta Neuropathol (2009) 2.67
Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. Proc Natl Acad Sci U S A (2008) 2.59
RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice. EMBO J (2004) 2.08
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics (2006) 1.88
TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes (2009) 1.83
Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma. Blood (2008) 1.71
SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase. J Immunol (2007) 1.68
Circle of Willis atherosclerosis: association with Alzheimer's disease, neuritic plaques and neurofibrillary tangles. Acta Neuropathol (2006) 1.64
Three-dimensional geometry of the tricuspid annulus in healthy subjects and in patients with functional tricuspid regurgitation: a real-time, 3-dimensional echocardiographic study. Circulation (2006) 1.63
Brain biochemistry in autopsied patients with essential tremor. Mov Disord (2011) 1.56
Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene. J Alzheimers Dis (2010) 1.54
Parkinson disease with dementia: comparing patients with and without Alzheimer pathology. Alzheimer Dis Assoc Disord (2009) 1.54
Reduced striatal tyrosine hydroxylase in incidental Lewy body disease. Acta Neuropathol (2007) 1.53
Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation. J Biol Chem (2009) 1.48
Postmortem interval effect on RNA and gene expression in human brain tissue. Cell Tissue Bank (2010) 1.46
High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice. J Neurochem (2008) 1.41
RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease. FASEB J (2009) 1.39
RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease. Curr Mol Med (2007) 1.38
HIV-1 clade-specific differences in the induction of neuropathogenesis. J Neurosci (2008) 1.37
Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease. J Neurosci (2006) 1.35
Atherosclerosis, vascular amyloidosis and brain hypoperfusion in the pathogenesis of sporadic Alzheimer's disease. Neurol Res (2004) 1.28
Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment. Mitochondrion (2006) 1.25
Gene expression correlates of neurofibrillary tangles in Alzheimer's disease. Neurobiol Aging (2005) 1.24
Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus. J Neuropathol Exp Neurol (2006) 1.23
Microglia activation and anti-inflammatory regulation in Alzheimer's disease. Mol Neurobiol (2010) 1.22
Secretory PLA2-IIA: a new inflammatory factor for Alzheimer's disease. J Neuroinflammation (2006) 1.20
Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression. J Neurochem (2007) 1.20
Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production. Neurobiol Dis (2007) 1.20
Submandibular gland needle biopsy for the diagnosis of Parkinson disease. Neurology (2014) 1.19
Interferon-alpha causes neuronal dysfunction in encephalitis. J Neurosci (2009) 1.18
Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology. FASEB J (2006) 1.13
Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues. Exp Cell Res (2006) 1.13
Antimalarial and cytotoxic activities of ethnopharmacologically selected medicinal plants from South Vietnam. J Ethnopharmacol (2006) 1.12
Alzheimer's disease and non-demented high pathology control nonagenarians: comparing and contrasting the biochemistry of cognitively successful aging. PLoS One (2011) 1.12
Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence. Retrovirology (2013) 1.09
Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome. Behav Brain Res (2010) 1.09
Quantitation of heteroplasmy of mtDNA sequence variants identified in a population of AD patients and controls by array-based resequencing. Mitochondrion (2006) 1.07
Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model. Exp Neurol (2008) 1.06
Age-related differences in white matter integrity and cognitive function are related to APOE status. Neuroimage (2010) 1.04
Striatal amyloid plaque density predicts Braak neurofibrillary stage and clinicopathological Alzheimer's disease: implications for amyloid imaging. J Alzheimers Dis (2012) 1.04
Suppressed insulin signaling and increased apoptosis in CD38-null islets. Diabetes (2006) 1.02
Effects of estrogen treatment on glutamate uptake in cultured human astrocytes derived from cortex of Alzheimer's disease patients. J Neurochem (2002) 1.02
Modeling Alzheimer's disease immune therapy mechanisms: interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide. J Neurosci Res (2002) 1.02
Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes. J Clin Invest (2010) 1.02
Biochemical increase in phosphorylated alpha-synuclein precedes histopathology of Lewy-type synucleinopathies. Brain Pathol (2012) 1.01
Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism. J Biol Chem (2010) 1.00
Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models. Brain Res (2010) 1.00
Substantia nigra Marinesco bodies are associated with decreased striatal expression of dopaminergic markers. J Neuropathol Exp Neurol (2004) 1.00
Validation of a 2-day water maze protocol in mice. Behav Brain Res (2008) 0.99
Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood-brain barrier: An in situ cerebral perfusion study. Neurochem Int (2009) 0.98
Geometry of the proximal isovelocity surface area in mitral regurgitation by 3-dimensional color Doppler echocardiography: difference between functional mitral regurgitation and prolapse regurgitation. Am Heart J (2007) 0.98
Marked microglial reaction in normal aging human substantia nigra: correlation with extraneuronal neuromelanin pigment deposits. Acta Neuropathol (2007) 0.98
Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations. Mol Neurodegener (2008) 0.96
Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease. Neuropharmacology (2009) 0.95
Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer's disease. Acta Neuropathol (2011) 0.94
Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy. Am J Pathol (2008) 0.93
Parkinson's disease, cortical dysfunction, and alpha-synuclein. Mov Disord (2011) 0.92
Continuous estrone treatment impairs spatial memory and does not impact number of basal forebrain cholinergic neurons in the surgically menopausal middle-aged rat. Horm Behav (2012) 0.92
Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome. Neurosci Res (2003) 0.92
Cerebral blood flow in Alzheimer's disease. Vasc Health Risk Manag (2012) 0.91
The cognitive effects of conjugated equine estrogens depend on whether menopause etiology is transitional or surgical. Endocrinology (2010) 0.90
Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice. J Neurochem (2013) 0.89
Cognitive-impairing effects of medroxyprogesterone acetate in the rat: independent and interactive effects across time. Psychopharmacology (Berl) (2011) 0.88
APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease. Neurobiol Aging (2012) 0.88
Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson's disease subjects. Neurol Res (2012) 0.87
Increased Alzheimer's disease neuropathology is associated with type 2 diabetes and ApoE ε.4 carrier status. Curr Alzheimer Res (2013) 0.87
Analysis of alkaloids in Lotus (Nelumbo nucifera Gaertn.) leaves by non-aqueous capillary electrophoresis using ultraviolet and mass spectrometric detection. J Chromatogr A (2013) 0.86
Competing molecular interactions of aPKC isoforms regulate neuronal polarity. Proc Natl Acad Sci U S A (2013) 0.86
Elucidating the role of 5-HT(1A) and 5-HT(7) receptors on 8-OH-DPAT-induced behavioral recovery after experimental traumatic brain injury. Neurosci Lett (2012) 0.86
Parkinson's disease dementia and potential therapeutic strategies. CNS Neurosci Ther (2010) 0.86
Relationship between left atrial and left ventricular function in hypertrophic cardiomyopathy: a real-time 3-dimensional echocardiographic study. J Am Soc Echocardiogr (2006) 0.86
Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samples. Biotechnol Prog (2013) 0.85
Construction, crystal structure and application of a recombinant protein that lacks the collagen-like region of BclA from Bacillus anthracis spores. Biotechnol Bioeng (2008) 0.85
Converging mediators from immune and trophic pathways to identify Parkinson disease dementia. Neurol Neuroimmunol Neuroinflamm (2016) 0.84
Reduced clinical and postmortem measures of cardiac pathology in subjects with advanced Alzheimer's Disease. BMC Geriatr (2011) 0.83
In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease. Lasers Surg Med (2013) 0.83
Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging. J Parkinsons Dis (2012) 0.82
Perturbations in calcium-mediated signal transduction in microglia from Alzheimer's disease patients. J Neurosci Res (2005) 0.82
Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease. Neurosci Lett (2009) 0.80
Diagnostic value of left ventricular outflow area in patients with hypertrophic cardiomyopathy: a real-time three-dimensional echocardiographic study. J Am Soc Echocardiogr (2008) 0.80
Isolation, kinetic analysis, and structural characterization of an antibody targeting the Bacillus anthracis major spore surface protein BclA. Proteins (2011) 0.80
Vietnamese traditional medicine from a pharmacist's perspective. Expert Rev Clin Pharmacol (2012) 0.79
The influence of Apolipoprotein E genotype on regional pathology in Alzheimer's disease. BMC Neurol (2013) 0.79
Determination of regurgitant orifice area with the use of a new three-dimensional flow convergence geometric assumption in functional mitral regurgitation. J Am Soc Echocardiogr (2008) 0.79
Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease. J Alzheimers Dis (2011) 0.78
BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains. Curr Alzheimer Res (2013) 0.78