Published in Neuron on March 27, 2008
Activity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10. Cell (2011) 2.52
The many faces of insulin-like peptide signalling in the brain. Nat Rev Neurosci (2012) 1.87
The cell biology of smell. J Cell Biol (2010) 1.40
IGF-1 Induces GHRH Neuronal Axon Elongation during Early Postnatal Life in Mice. PLoS One (2017) 1.39
Awake intranasal insulin delivery modifies protein complexes and alters memory, anxiety, and olfactory behaviors. J Neurosci (2009) 1.35
Cellular strategies of axonal pathfinding. Cold Spring Harb Perspect Biol (2010) 1.33
A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories. EMBO J (2011) 1.20
Topographic mapping--the olfactory system. Cold Spring Harb Perspect Biol (2010) 1.08
Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1. J Gerontol A Biol Sci Med Sci (2012) 1.06
Insulin-like growth factors in the peripheral nervous system. Endocrinology (2008) 1.00
Complexin activates exocytosis of distinct secretory vesicles controlled by different synaptotagmins. J Neurosci (2013) 0.96
Activation of ERK1/2 and PI3K/Akt by IGF-1 on GAP-43 expression in DRG neurons with excitotoxicity induced by glutamate in vitro. Cell Mol Neurobiol (2011) 0.91
A Drosophila model for fetal alcohol syndrome disorders: role for the insulin pathway. Dis Model Mech (2011) 0.90
Insulin-like growth factor-1 in CNS and cerebrovascular aging. Front Aging Neurosci (2013) 0.88
Growth hormone, insulin-like growth factor-1 and the aging brain. Exp Gerontol (2014) 0.86
Developmental Coordination of Gene Expression between Synaptic Partners During GABAergic Circuit Assembly in Cerebellar Cortex. Front Neural Circuits (2012) 0.86
GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling. Hum Mol Genet (2009) 0.85
Wiring Olfaction: The Cellular and Molecular Mechanisms that Guide the Development of Synaptic Connections from the Nose to the Cortex. Front Neurosci (2009) 0.83
The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain. J Neurosci (2010) 0.81
The role of insulin-like growth factor-I in the physiopathology of hearing. Front Mol Neurosci (2011) 0.79
IGF-I: A Key Growth Factor that Regulates Neurogenesis and Synaptogenesis from Embryonic to Adult Stages of the Brain. Front Neurosci (2016) 0.79
Divergent and convergent roles for insulin-like peptides in the worm, fly and mammalian nervous systems. Invert Neurosci (2014) 0.78
Ipsilateral and Contralateral Retinal Ganglion Cells Express Distinct Genes during Decussation at the Optic Chiasm. eNeuro (2016) 0.76
Primary Postnatal Dorsal Root Ganglion Culture from Conventionally Slaughtered Calves. PLoS One (2016) 0.75
Alcohol enhances the psychostimulant and conditioning effects of mephedrone in adolescent mice; postulation of unique roles of D3 receptors and BDNF in place preference acquisition. Br J Pharmacol (2015) 0.75
How membrane dysfunction influences neuronal survival pathways in sphingolipid storage disorders. J Neurosci Res (2016) 0.75
IGF1-Dependent Synaptic Plasticity of Mitral Cells in Olfactory Memory during Social Learning. Neuron (2017) 0.75
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell (1993) 10.36
Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev (1995) 9.54
Visualizing an olfactory sensory map. Cell (1996) 8.79
Role of insulin-like growth factors in embryonic and postnatal growth. Cell (1993) 8.22
Allelic inactivation regulates olfactory receptor gene expression. Cell (1994) 5.93
A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature (1990) 5.47
Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell (1994) 4.79
Topographic organization of sensory projections to the olfactory bulb. Cell (1994) 4.74
A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell (1993) 4.42
The olfactory bulb: coding and processing of odor molecule information. Science (1999) 3.69
Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell (1993) 3.53
A neuronal identity code for the odorant receptor-specific and activity-dependent axon sorting. Cell (2006) 3.15
Auditory system development: primary auditory neurons and their targets. Annu Rev Neurosci (2002) 3.09
Turning of nerve growth cones induced by neurotransmitters. Nature (1994) 3.06
Odorant receptor-derived cAMP signals direct axonal targeting. Science (2006) 3.03
Molecular gradients and development of retinotopic maps. Annu Rev Neurosci (2005) 2.92
Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping. Nature (2006) 2.92
IGF-I specifically enhances axon outgrowth of corticospinal motor neurons. Nat Neurosci (2006) 2.82
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature (2005) 2.78
Odorant receptors govern the formation of a precise topographic map. Cell (1998) 2.60
Maps of odorant molecular features in the Mammalian olfactory bulb. Physiol Rev (2006) 2.43
Axonal wiring in the mouse olfactory system. Annu Rev Cell Dev Biol (2006) 2.41
A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell (2004) 2.24
Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons. Neuron (1995) 2.19
Genetics of mouse growth. Int J Dev Biol (1998) 2.08
Signal transduction underlying growth cone guidance by diffusible factors. Curr Opin Neurobiol (1999) 1.92
Axonal ephrin-As and odorant receptors: coordinate determination of the olfactory sensory map. Cell (2003) 1.77
An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons. Neuron (1998) 1.76
Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance. Neuron (1999) 1.65
Continuous and overlapping expression domains of odorant receptor genes in the olfactory epithelium determine the dorsal/ventral positioning of glomeruli in the olfactory bulb. J Neurosci (2005) 1.64
Functional identification of a goldfish odorant receptor. Neuron (1999) 1.62
Nerve growth cone guidance mediated by G protein-coupled receptors. Nat Neurosci (2002) 1.39
Misguided axonal projections, neural cell adhesion molecule 180 mRNA upregulation, and altered behavior in mice deficient for the close homolog of L1. Mol Cell Biol (2002) 1.36
IGF-1 receptor is essential for the establishment of hippocampal neuronal polarity. Nat Neurosci (2006) 1.31
Development of P2 olfactory glomeruli in P2-internal ribosome entry site-tau-LacZ transgenic mice. J Neurosci (1999) 1.29
Aberrant sensory innervation of the olfactory bulb in neuropilin-2 mutant mice. J Neurosci (2002) 1.21
In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: evidence that IGF-I increases proliferation of granule cell progenitors. Brain Res Dev Brain Res (1996) 1.20
Semaphorin 3A is required for guidance of olfactory axons in mice. J Neurosci (2000) 1.20
The formation of a cortical somatotopic map. Trends Neurosci (1995) 1.18
PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone. J Cell Sci (2005) 1.17
Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb. J Neurosci (2007) 1.08
Role of galectin-1 in the developing mouse olfactory system. Dev Biol (1996) 1.06
Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner. J Neurosci (2001) 1.05
Distorted odor maps in the olfactory bulb of semaphorin 3A-deficient mice. J Neurosci (2003) 1.04
Sorting and convergence of primary olfactory axons are independent of the olfactory bulb. J Comp Neurol (2003) 1.02
Spatial patterns of gene expression in the olfactory bulb. Proc Natl Acad Sci U S A (2004) 1.01
Disrupted compartmental organization of axons and dendrites within olfactory glomeruli of mice deficient in the olfactory cell adhesion molecule, OCAM. Mol Cell Neurosci (2006) 0.99
Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system. Proc Natl Acad Sci U S A (1988) 0.98
Roles of odorant receptors in projecting axons in the mouse olfactory system. Curr Opin Neurobiol (2007) 0.95
Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor. Endocrinology (1992) 0.94
The central pathway of primary olfactory axons is abnormal in mice lacking the N-CAM-180 isoform. J Neurobiol (1997) 0.91
Two mirror-image sensory maps with domain organization in the mouse main olfactory bulb. Neuroreport (2000) 0.90
Adeno-associated viral-mediated insulin-like growth factor delivery protects motor neurons in vitro. Neuromolecular Med (2004) 0.90
Primary olfactory axons form ectopic glomeruli in mice lacking p75NTR. J Comp Neurol (2000) 0.87
Subzonal organization of olfactory sensory neurons projecting to distinct glomeruli within the mouse olfactory bulb. J Comp Neurol (2003) 0.86
Multiple axon guidance cues establish the olfactory topographic map: how do these cues interact? Int J Dev Biol (2002) 0.85
Development of the vertebrate main olfactory system. Curr Opin Neurobiol (1999) 0.84
Spatiotemporal distribution of the insulin-like growth factor receptor in the rat olfactory bulb. Neurochem Res (2003) 0.81
Laminar disorganisation of mitral cells in the olfactory bulb does not affect topographic targeting of primary olfactory axons. Brain Res (2002) 0.79
Expression of insulin-like growth factor family in the rat olfactory epithelium. Anat Embryol (Berl) (2002) 0.78
Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res (2002) 40.03
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia. Nature (2011) 5.78
Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cell (2008) 5.04
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell (2012) 4.88
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. J Biol Chem (2002) 4.52
Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Mol Cell Biol (2005) 4.00
Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Cell Stem Cell (2008) 3.15
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice. Proc Natl Acad Sci U S A (2006) 2.92
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature (2005) 2.78
Generation of functional insulin-producing cells in the gut by Foxo1 ablation. Nat Genet (2012) 2.75
Functional genomic analysis of oligodendrocyte differentiation. J Neurosci (2006) 2.64
A heterozygous moth genome provides insights into herbivory and detoxification. Nat Genet (2013) 2.13
The Sp1-related transcription factors sp5 and sp5-like act downstream of Wnt/beta-catenin signaling in mesoderm and neuroectoderm patterning. Curr Biol (2005) 2.09
Proliferation and migration of label-retaining cells of the kidney papilla. J Am Soc Nephrol (2009) 1.99
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature (2009) 1.94
Testis determination requires insulin receptor family function in mice. Nature (2003) 1.94
Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor. J Clin Invest (2002) 1.93
Semaphorin-3A guides radial migration of cortical neurons during development. Nat Neurosci (2007) 1.89
The molecular basis for water taste in Drosophila. Nature (2010) 1.81
Learned recognition of maternal signature odors mediates the first suckling episode in mice. Curr Biol (2012) 1.63
Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium. Am J Pathol (2004) 1.59
Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation. J Biol Chem (2008) 1.58
Long-range Ca2+ signaling from growth cone to soma mediates reversal of neuronal migration induced by slit-2. Cell (2007) 1.50
The odorant receptor repertoire of teleost fish. BMC Genomics (2005) 1.46
Igf1r as a therapeutic target in a mouse model of basal-like breast cancer. Proc Natl Acad Sci U S A (2009) 1.45
The cell biology of smell. J Cell Biol (2010) 1.40
Nerve growth cone guidance mediated by G protein-coupled receptors. Nat Neurosci (2002) 1.39
Molecular analysis of gene expression in the developing pontocerebellar projection system. Neuron (2002) 1.37
Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination. J Neurosci (2003) 1.31
The hormonal action of IGF1 in postnatal mouse growth. Proc Natl Acad Sci U S A (2008) 1.31
Ca2+-dependent regulation of rho GTPases triggers turning of nerve growth cones. J Neurosci (2005) 1.25
Using microarrays to facilitate positional cloning: identification of tomosyn as an inhibitor of neurosecretion. PLoS Genet (2005) 1.25
Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling. Dev Biol (2002) 1.24
Interconnected carbon nanosheets derived from hemp for ultrafast supercapacitors with high energy. ACS Nano (2013) 1.24
Neuronostatin encoded by the somatostatin gene regulates neuronal, cardiovascular, and metabolic functions. J Biol Chem (2008) 1.19
Molecular determinants of ligand selectivity in a vertebrate odorant receptor. J Neurosci (2004) 1.15
Effects and action mechanisms of berberine and Rhizoma coptidis on gut microbes and obesity in high-fat diet-fed C57BL/6J mice. PLoS One (2011) 1.14
High-density sodium and lithium ion battery anodes from banana peels. ACS Nano (2014) 1.14
Developmental and insecticide-resistant insights from the de novo assembled transcriptome of the diamondback moth, Plutella xylostella. Genomics (2012) 1.11
The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids. BMC Genomics (2006) 1.10
Analysis of gene expression in the developing mouse retina. Proc Natl Acad Sci U S A (2003) 1.09
Odorant receptor gene regulation: implications from genomic organization. Trends Genet (2002) 1.08
Evasion mechanisms to Igf1r inhibition in rhabdomyosarcoma. Mol Cancer Ther (2011) 1.07
p63 regulates olfactory stem cell self-renewal and differentiation. Neuron (2011) 1.06
Foxg1 is required for development of the vertebrate olfactory system. J Neurosci (2008) 1.05
A dominant-negative form of mouse SOX2 induces trophectoderm differentiation and progressive polyploidy in mouse embryonic stem cells. J Biol Chem (2007) 1.04
Independent regulation of skeletal growth by Ihh and IGF signaling. Dev Biol (2006) 1.03
Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance. J Biol Chem (2002) 1.02
Wafer-level photocatalytic water splitting on GaN nanowire arrays grown by molecular beam epitaxy. Nano Lett (2011) 1.02
Spatial patterns of gene expression in the olfactory bulb. Proc Natl Acad Sci U S A (2004) 1.01
Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis. Diabetes (2012) 1.01
Analysis of gene expression during neurite outgrowth and regeneration. BMC Neurosci (2007) 1.00
The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium. Diabetes (2011) 1.00
Temperature-dependent nonradiative recombination processes in GaN-based nanowire white-light-emitting diodes on silicon. Nanotechnology (2012) 0.99
A mouse model of uterine leiomyosarcoma. Am J Pathol (2004) 0.99
Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase. J Neurosci (2014) 0.98
Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice. Diabetes (2012) 0.97
Transcriptome analysis of microRNAs in developing cerebral cortex of rat. BMC Genomics (2012) 0.96
Carbon nanosheet frameworks derived from peat moss as high performance sodium ion battery anodes. ACS Nano (2013) 0.96
Mosaic analysis of insulin receptor function. J Clin Invest (2004) 0.95
A novel three-dimensional quantitative coronary angiography system: In-vivo comparison with intravascular ultrasound for assessing arterial segment length. Catheter Cardiovasc Interv (2010) 0.95
Prostatic intraepithelial neoplasia and adenocarcinoma in mice expressing a probasin-Neu oncogenic transgene. Carcinogenesis (2006) 0.95
Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells. J Biol Chem (2010) 0.94
Undifferentiated embryonal sarcoma of the liver in a child: A case report and review of the literature. Oncol Lett (2012) 0.94
Next-generation sequencing-based mRNA and microRNA expression profiling analysis revealed pathways involved in the rapid growth of developing culms in Moso bamboo. BMC Plant Biol (2013) 0.94
miRNA-mediated functional changes through co-regulating function related genes. PLoS One (2010) 0.91
'Designer' tumors in mice. Oncogene (2004) 0.90
Role of a ubiquitously expressed receptor in the vertebrate olfactory system. J Neurosci (2013) 0.90
Circulating Tumor Cell Analyses in Patients With Esophageal Squamous Cell Carcinoma Using Epithelial Marker-Dependent and -Independent Approaches. Medicine (Baltimore) (2015) 0.89
Primary squamous cell carcinoma of the liver: A case report and review of the literature. Oncol Lett (2012) 0.89
Nestin is essential for mitogen-stimulated proliferation of neural progenitor cells. Mol Cell Neurosci (2010) 0.88
MicroRNA-126 regulates EPCs function: implications for a role of miR-126 in preeclampsia. J Cell Biochem (2013) 0.88
Low level prenatal exposure to methylmercury disrupts neuronal migration in the developing rat cerebral cortex. Toxicology (2012) 0.88
Early anti-oxidative and anti-proliferative curcumin effects on neuroglioma cells suggest therapeutic targets. Neurochem Res (2008) 0.87
The transcription factor Cux1 regulates dendritic morphology of cortical pyramidal neurons. PLoS One (2010) 0.87
Full-color InGaN/GaN dot-in-a-wire light emitting diodes on silicon. Nanotechnology (2011) 0.86
Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function. PLoS One (2011) 0.86
Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat. PLoS One (2012) 0.86
A new hydrodynamic approach by infusion of drag-reducing polymers to improve left ventricular function in rats with myocardial infarction. Int J Cardiol (2011) 0.85
Pbx homeodomain proteins pattern both the zebrafish retina and tectum. BMC Dev Biol (2007) 0.85
High-potency olfactory receptor agonists discovered by virtual high-throughput screening: molecular probes for receptor structure and olfactory function. Neuron (2008) 0.85
Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development. Hum Mol Genet (2012) 0.85
Anodes for sodium ion batteries based on tin-germanium-antimony alloys. ACS Nano (2014) 0.84
SDF-1 activates papillary label-retaining cells during kidney repair from injury. Am J Physiol Renal Physiol (2012) 0.84
Genome-wide and molecular evolution analysis of the Poplar KT/HAK/KUP potassium transporter gene family. Ecol Evol (2012) 0.83
Role of enolase-1 in response to hypoxia in breast cancer: exploring the mechanisms of action. Oncol Rep (2013) 0.83
Irs2 inactivation suppresses tumor progression in Pten+/- mice. Am J Pathol (2008) 0.83
Controlling electron overflow in phosphor-free InGaN/GaN nanowire white light-emitting diodes. Nano Lett (2012) 0.83
Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci (2011) 0.82
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition. J Cell Sci (2011) 0.82
ALD TiO2 coated silicon nanowires for lithium ion battery anodes with enhanced cycling stability and coulombic efficiency. Phys Chem Chem Phys (2013) 0.82
Scent of a stem cell. Nat Neurosci (2007) 0.81
Genomic imprinting: piece of cake. Nature (2002) 0.81