Turning of nerve growth cones induced by neurotransmitters.

Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid. Mol Cell Biol (1997) 3.44

The dynamic effects of nicotine on the developing brain. Pharmacol Ther (2009) 3.01

Biomolecular gradients in cell culture systems. Lab Chip (2007) 2.96

GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex. Neuron (2007) 2.23

Guiding neuronal growth cones using Ca2+ signals. Trends Cell Biol (2004) 1.97

BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin. J Cell Biol (2007) 1.66

Wnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanisms. J Neurosci (2009) 1.59

Activity-dependent development of inhibitory synapses and innervation pattern: role of GABA signalling and beyond. J Physiol (2009) 1.53

Calcium signaling in neuronal development. Cold Spring Harb Perspect Biol (2011) 1.52

Transient receptor potential canonical 5 channels activate Ca2+/calmodulin kinase Igamma to promote axon formation in hippocampal neurons. J Neurosci (2009) 1.48

Ena/VASP: proteins at the tip of the nervous system. Curr Opin Neurobiol (2008) 1.37

Wiring the brain: the biology of neuronal guidance. Cold Spring Harb Perspect Biol (2010) 1.33

Second messengers and membrane trafficking direct and organize growth cone steering. Nat Rev Neurosci (2011) 1.32

Asymmetric redistribution of GABA receptors during GABA gradient sensing by nerve growth cones analyzed by single quantum dot imaging. Proc Natl Acad Sci U S A (2007) 1.30

Phosphorylation of zipcode binding protein 1 is required for brain-derived neurotrophic factor signaling of local beta-actin synthesis and growth cone turning. J Neurosci (2010) 1.29

Nicotine-induced plasticity during development: modulation of the cholinergic system and long-term consequences for circuits involved in attention and sensory processing. Neuropharmacology (2008) 1.26

A hybrid microfluidic-vacuum device for direct interfacing with conventional cell culture methods. BMC Biotechnol (2007) 1.25

Dynamics of axonal microtubules regulate the topology of new membrane insertion into the growing neurites. J Cell Biol (1998) 1.23

GABA and neuroligin signaling: linking synaptic activity and adhesion in inhibitory synapse development. Curr Opin Neurobiol (2008) 1.23

Requirement of dendritic Akt degradation by the ubiquitin-proteasome system for neuronal polarity. J Cell Biol (2006) 1.20

Calcium mediates bidirectional growth cone turning induced by myelin-associated glycoprotein. Neuron (2004) 1.20

beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones. Mol Brain (2008) 1.19

Actin dynamics in growth cone motility and navigation. J Neurochem (2013) 1.16

Ca(2+) signaling evoked by activation of Na(+) channels and Na(+)/Ca(2+) exchangers is required for GABA-induced NG2 cell migration. J Cell Biol (2009) 1.14

Role of IGF signaling in olfactory sensory map formation and axon guidance. Neuron (2008) 1.04

CRYP-2/cPTPRO is a neurite inhibitory repulsive guidance cue for retinal neurons in vitro. J Cell Biol (2001) 1.04

Neurotransmitter secretion along growing nerve processes: comparison with synaptic vesicle exocytosis. J Cell Biol (1999) 1.02

Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning. J Neurosci (2009) 1.02

Wnt/calcium signaling mediates axon growth and guidance in the developing corpus callosum. Dev Neurobiol (2011) 1.01

Asymmetric endocytosis and remodeling of beta1-integrin adhesions during growth cone chemorepulsion by MAG. Nat Neurosci (2010) 1.00

Spatial targeting of type II protein kinase A to filopodia mediates the regulation of growth cone guidance by cAMP. J Cell Biol (2007) 0.99

Novel signaling pathways mediating reciprocal control of keratinocyte migration and wound epithelialization through M3 and M4 muscarinic receptors. J Cell Biol (2004) 0.99

Regulation of axonal development by natriuretic peptide hormones. Proc Natl Acad Sci U S A (2009) 0.98

Cell-autonomous inhibition of alpha 7-containing nicotinic acetylcholine receptors prevents death of parasympathetic neurons during development. J Neurosci (2007) 0.98

Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening. Neuron (2009) 0.96

Axon guidance by growth-rate modulation. Proc Natl Acad Sci U S A (2010) 0.96

Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms. Proc Natl Acad Sci U S A (2010) 0.95

Models of axon guidance and bundling during development. Proc Biol Sci (1999) 0.95

GABA signaling promotes synapse elimination and axon pruning in developing cortical inhibitory interneurons. J Neurosci (2012) 0.95

Synaptogenesis in the CNS: an odyssey from wiring together to firing together. J Physiol (2003) 0.93

A mathematical framework for modeling axon guidance. Bull Math Biol (2006) 0.93

Asymmetric PI(3,4,5)P3 and Akt signaling mediates chemotaxis of axonal growth cones. J Neurosci (2011) 0.92

Outgrowth of neurites from NIE-115 neuroblastoma cells is prevented on repulsive substrates through the action of PAK. Mol Cell Biol (2005) 0.92

alpha3alpha5beta2-Nicotinic acetylcholine receptor contributes to the wound repair of the respiratory epithelium by modulating intracellular calcium in migrating cells. Am J Pathol (2006) 0.92

Ca2+ influx and activation of a cation current are coupled to intracellular Ca2+ release in peptidergic neurons of Aplysia californica. J Physiol (1996) 0.90

Growth cone collapse through coincident loss of actin bundles and leading edge actin without actin depolymerization. J Cell Biol (2001) 0.89

Primary neuron culture for nerve growth and axon guidance studies in zebrafish (Danio rerio). PLoS One (2013) 0.89

The influence of in utero exposure to smoking on sleep patterns in preterm neonates. Sleep (2008) 0.88

A subset of signal transduction pathways is required for hippocampal growth cone collapse induced by ephrin-A5. Dev Neurobiol (2008) 0.88

Uncoupling nicotine mediated motoneuron axonal pathfinding errors and muscle degeneration in zebrafish. Toxicol Appl Pharmacol (2008) 0.87

Acute synaptic modulation by nicotinic agonists in developing cerebellar Purkinje cells of the rat. J Physiol (2002) 0.87

Modeling the role of myosin 1c in neuronal growth cone turning. Biophys J (2003) 0.87

Investigating dynamic structural and mechanical changes of neuroblastoma cells associated with glutamate-mediated neurodegeneration. Sci Rep (2014) 0.86

Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex. Nat Methods (2014) 0.85

Smoking during pregnancy: postnatal effects on arousal and attentional brain systems. Neurotoxicology (2007) 0.85

Regulation of chemotropic guidance of nerve growth cones by microRNA. Mol Brain (2011) 0.85

Effects of surface asymmetry on neuronal growth. PLoS One (2014) 0.85

Secondary motoneurons in juvenile and adult zebrafish: axonal pathfinding errors caused by embryonic nicotine exposure. J Comp Neurol (2009) 0.85

Cloning and spatiotemporal expression of zebrafish neuronal nicotinic acetylcholine receptor alpha 6 and alpha 4 subunit RNAs. Dev Dyn (2009) 0.85

Anesthetics interfere with axon guidance in developing mouse neocortical neurons in vitro via a γ-aminobutyric acid type A receptor mechanism. Anesthesiology (2013) 0.84

Wnt5a evokes cortical axon outgrowth and repulsive guidance by tau mediated reorganization of dynamic microtubules. Dev Neurobiol (2013) 0.84

Nonvesicular release of acetylcholine is required for axon targeting in the Drosophila visual system. Proc Natl Acad Sci U S A (2004) 0.84

Astrocytic Ca(2+) waves guide CNS growth cones to remote regions of neuronal activity. PLoS One (2008) 0.84

High-content neurite development study using optically patterned substrates. PLoS One (2012) 0.83

A mechanism for the polarity formation of chemoreceptors at the growth cone membrane for gradient amplification during directional sensing. PLoS One (2010) 0.83

Calcium-dependent glutamate release during neuronal development and synaptogenesis: different involvement of omega-agatoxin IVA- and omega-conotoxin GVIA-sensitive channels. Proc Natl Acad Sci U S A (1995) 0.82

Distribution of neuronal growth-promoting factors and cytoskeletal proteins in altered neurites in Alzheimer's disease and non-demented elderly. Acta Neuropathol (1995) 0.82

Amplification and temporal filtering during gradient sensing by nerve growth cones probed with a microfluidic assay. Biophys J (2012) 0.80

Enabling systems biology approaches through microfabricated systems. Anal Chem (2013) 0.80

Early exposure to nicotine during critical periods of brain development: Mechanisms and consequences. J Pediatr Biochem (2010) 0.80

Axon response to guidance cues is stimulated by acetylcholine in Caenorhabditis elegans. Genetics (2011) 0.80

Release of acetylcholine from embryonic myocytes in Xenopus cell cultures. J Physiol (1998) 0.79

Crosstalk between second messengers predicts the motility of the growth cone. Sci Rep (2013) 0.79

Fluorescence imaging of local membrane electric fields during the excitation of single neurons in culture. Biophys J (1995) 0.79

Differential role of PTEN phosphatase in chemotactic growth cone guidance. J Biol Chem (2013) 0.79

Live cell imaging of neuronal growth cone motility and guidance in vitro. Methods Mol Biol (2011) 0.79

Autocatalytic loop, amplification and diffusion: a mathematical and computational model of cell polarization in neural chemotaxis. PLoS Comput Biol (2009) 0.79

Covalently immobilized biomolecule gradient on hydrogel surface using a gradient generating microfluidic device for a quantitative mesenchymal stem cell study. Biomicrofluidics (2012) 0.79

Elevated kynurenine pathway metabolism during neurodevelopment: Implications for brain and behavior. Neuropharmacology (2016) 0.79

A critical role for STIM1 in filopodial calcium entry and axon guidance. Mol Brain (2013) 0.78

X-linked microtubule-associated protein, Mid1, regulates axon development. Proc Natl Acad Sci U S A (2013) 0.78

Acetylcholine influences growth cone motility and morphology of developing thalamic axons. Cell Adh Migr (2008) 0.77

Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using Parkinsonian α6(∗) nAChR gain-of-function mice. Neuroscience (2015) 0.77

A simple method for using silicone elastomer masks for quantitative analysis of cell migration without cellular damage or substrate disruption. Cell Adh Migr (2013) 0.77

Netrin-1 stimulates developing GnRH neurons to extend neurites to the median eminence in a calcium- dependent manner. PLoS One (2012) 0.77

Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines. Front Cell Neurosci (2015) 0.76

In vivo Calcium Signaling during Synaptic Refinement at the Drosophila Neuromuscular Junction. J Neurosci (2017) 0.76

Optogenetic activation of axon guidance receptors controls direction of neurite outgrowth. Sci Rep (2016) 0.75

Temporal analysis of protozoan lysis in a microfluidic device. Lab Chip (2009) 0.75

An Automated Strategy for Unbiased Morphometric Analyses and Classifications of Growth Cones In Vitro. PLoS One (2015) 0.75

Constitutive secretion of exogenous neurotransmitter by nonneuronal cells: implications for neuronal secretion. Biophys J (1998) 0.75

Multi-phasic bi-directional chemotactic responses of the growth cone. Sci Rep (2016) 0.75

A hybrid computational model to predict chemotactic guidance of growth cones. Sci Rep (2015) 0.75

Neurobiology. Just a chemical attraction. Nature (1994) 0.75

Low-level laser irradiation modulates brain-derived neurotrophic factor mRNA transcription through calcium-dependent activation of the ERK/CREB pathway. Lasers Med Sci (2016) 0.75

Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type. J Neurosci (1998) 11.63

Voltage clamp studies of a transient outward membrane current in gastropod neural somata. J Physiol (1971) 9.27

The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18

Inward and delayed outward membrane currents in isolated neural somata under voltage clamp. J Physiol (1971) 6.86

Prediction of repetitive firing behaviour from voltage clamp data on an isolated neurone soma. J Physiol (1971) 4.85

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion. Cell (1999) 4.25

Lateral diffusion of phodopsin in Necturus rods. Exp Eye Res (1973) 4.02

Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature (1993) 3.09

cAMP-induced switching in turning direction of nerve growth cones. Nature (1997) 2.90

Calcium stores regulate the polarity and input specificity of synaptic modification. Nature (2000) 2.84

The role of electro-osmosis in the electric-field-induced movement of charged macromolecules on the surfaces of cells. Biophys J (1981) 2.81

Electrical activity and development of neural circuits. Nat Neurosci (2001) 2.79

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron (1994) 2.65

cAMP-dependent growth cone guidance by netrin-1. Neuron (1997) 2.60

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions. Proc Natl Acad Sci U S A (1989) 2.53

Spatially resolved calcium dynamics of mammalian Purkinje cells in cerebellar slice. Science (1988) 2.48

Measurement of calcium influx under voltage clamp in molluscan neurones using the metallochromic dye arsenazo III. J Physiol (1979) 2.36

Calcium current in molluscan neurones: measurement under conditions which maximize its visibility. J Physiol (1979) 2.27

A study of pace-maker activity in intestinal smooth muscle. J Physiol (1974) 2.24

Asymmetric modulation of cytosolic cAMP activity induces growth cone turning. J Neurosci (1992) 2.18

Propagation of activity-dependent synaptic depression in simple neural networks. Nature (1997) 2.07

Spontaneous release of transmitter from growth cones of embryonic neurones. Nature (1983) 2.06

Protein diffusion in cell membranes: some biological implications. Int Rev Cytol (1984) 2.03

Digital imaging of free calcium changes and of spatial gradients in growing processes in single, mammalian central nervous system cells. Proc Natl Acad Sci U S A (1986) 2.01

Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC. Neuron (1997) 2.00

Dendritic spines as individual neuronal compartments for synaptic Ca2+ responses. Nature (1991) 1.98

Signal transduction underlying growth cone guidance by diffusible factors. Curr Opin Neurobiol (1999) 1.92

Orientation of neurite growth by extracellular electric fields. J Neurosci (1982) 1.92

A long-term depression of AMPA currents in cultured cerebellar Purkinje neurons. Neuron (1991) 1.90

Rates of membrane-associated reactions: reduction of dimensionality revisited. J Cell Biol (1986) 1.85

Essential role of filopodia in chemotropic turning of nerve growth cone induced by a glutamate gradient. J Neurosci (1996) 1.83

Neural repetitive firing: modifications of the Hodgkin-Huxley axon suggested by experimental results from crustacean axons. Biophys J (1977) 1.77

Intracellular pH changes induced by calcium influx during electrical activity in molluscan neurons. J Gen Physiol (1980) 1.75

Optical imaging of calcium accumulation in hippocampal pyramidal cells during synaptic activation. Nature (1989) 1.61

Neurites grow faster towards the cathode than the anode in a steady field. J Exp Zool (1979) 1.60

Participation of postsynaptic PKC in cerebellar long-term depression in culture. Science (1991) 1.55

Time course separation of two inward currents in molluscan neurons. Brain Res (1977) 1.53

Calcium regulation by and buffer capacity of molluscan neurons during calcium transients. Cell Calcium (1988) 1.52

Diffusional transport of macromolecules in developing nerve processes. J Neurosci (1992) 1.51

Efficacy and safety of radiation synovectomy with Yttrium-90: a retrospective long-term analysis of 164 applications in 82 patients. Br J Rheumatol (1993) 1.46

Long-term synaptic depression. Annu Rev Neurosci (1995) 1.44

Electrophoretic movement and localisation of acetylcholine receptors in the embryonic muscle cell membrane. Nature (1978) 1.44

Stoichiometry and apparent dissociation constant of the calcium-arsenazo III reaction under physiological conditions. Biophys J (1980) 1.41

Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses. Neuron (1992) 1.41

HCV genotype 1 subtypes (1a and 1b): similarities and differences in clinical features and therapeutic outcome. Hepatol Int (2014) 1.41

Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury. J Neurosci (2001) 1.39

Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil. J Neurosci (1997) 1.39

Contact-induced redistribution of specific membrane components: local accumulation and development of adhesion. J Cell Biol (1986) 1.38

Lateral electromigration and diffusion of Fc epsilon receptors on rat basophilic leukemia cells: effects of IgE binding. J Cell Biol (1984) 1.34

Localization of cell membrane components by surface diffusion into a "trap". Biophys J (1981) 1.34

Presynaptic depolarization facilitates neurotrophin-induced synaptic potentiation. Nat Neurosci (1999) 1.32

Cloning, sequencing, and expression of the genes encoding the adenosylcobalamin-dependent ethanolamine ammonia-lyase of Salmonella typhimurium. J Biol Chem (1990) 1.31

Micromolar Ca2+ transients in dendritic spines of hippocampal pyramidal neurons in brain slice. Neuron (1995) 1.31

Dissociated neurons from normal and mutant Drosophila larval central nervous system in cell culture. J Neurosci (1983) 1.30

Synaptotagmin: a calcium-sensitive inhibitor of exocytosis? Cell (1993) 1.30

Initial events in the formation of neuromuscular synapse: rapid induction of acetylcholine release from embryonic neuron. Proc Natl Acad Sci U S A (1986) 1.29

Forward plasma membrane flow in growing nerve processes. Science (1993) 1.28

Slow repetitive activity from fast conductance changes in neurons. Fed Proc (1978) 1.27

Relations between ameboid movement and membrane-controlled electrical currents. J Gen Physiol (1977) 1.27

Retrograde signaling in the development and modification of synapses. Physiol Rev (1998) 1.26

Potentiation of developing synapses by postsynaptic release of neurotrophin-4. Neuron (1997) 1.26

Depolarization- and transmitter-induced changes in intracellular Ca2+ of rat cerebellar granule cells in explant cultures. J Neurosci (1987) 1.23

Ca2+ release from intracellular stores induced by afferent stimulation of CA3 pyramidal neurons in hippocampal slices. J Neurophysiol (1996) 1.22

Perturbation of the direction of neurite growth by pulsed and focal electric fields. J Neurosci (1984) 1.22

Quantal transmitter secretion from myocytes loaded with acetylcholine. Nature (1992) 1.21

Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor. J Neurosci (1996) 1.21

Studies of nerve-muscle interactions in Xenopus cell culture: analysis of early synaptic currents. J Neurosci (1989) 1.21

Release of acetylcholine from embryonic neurons upon contact with muscle cell. J Neurosci (1985) 1.19

Synapsin IIa accelerates functional development of neuromuscular synapses. Proc Natl Acad Sci U S A (1994) 1.19

Studies of nerve-muscle interactions in Xenopus cell culture: fine structure of early functional contacts. J Neurosci (1989) 1.18

Evoked release of acetylcholine from the growing embryonic neuron. Proc Natl Acad Sci U S A (1987) 1.17

Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures. J Neurosci (1987) 1.16

Passive signal propagation and membrane properties in median photoreceptors of the giant barnacle. J Physiol (1977) 1.15

Calcium-dependent transmitter secretion from fibroblasts: modulation by synaptotagmin I. Neuron (1995) 1.15

Calcium-dependent transmitter secretion reconstituted in Xenopus oocytes: requirement for synaptophysin. Science (1992) 1.15

Long-term results of a clinical trial of nadolol with or without isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis. Hepatology (2000) 1.13

Involvement of the temporomandibular joints in ankylosing spondylitis (Bechterew's disease). J Craniomaxillofac Surg (1996) 1.10

Bidirectional synaptic plasticity correlated with the magnitude of dendritic calcium transients above a threshold. J Neurophysiol (2001) 1.10

Properties of rat and mouse beta-glucuronidase mRNA and cDNA, including evidence for sequence polymorphism and genetic regulation of mRNA levels. Gene (1985) 1.09

Interaction between longitudinal and circular muscle in intestine of cat. J Physiol (1977) 1.08

The role of Ca2+ entry via synaptically activated NMDA receptors in the induction of long-term potentiation. Neuron (1993) 1.08

Neural repetitive firing: a comparative study of membrane properties of crustacean walking leg axons. J Neurophysiol (1975) 1.07

Topographical rearrangement of acetylcholine receptors alters channel kinetics. Nature (1983) 1.07

Accelerated structural maturation induced by synapsin I at developing neuromuscular synapses of Xenopus laevis. Eur J Neurosci (1995) 1.06

Overexpression of synaptophysin enhances neurotransmitter secretion at Xenopus neuromuscular synapses. J Neurosci (1995) 1.06

Mobility and localization of proteins in excitable membranes. Annu Rev Neurosci (1985) 1.06

Electrically and chemically mediated increases in intracellular calcium in neuronal growth cones. J Neurosci (1987) 1.05

Redistribution of cell surface receptors induced by cell-cell contact. J Cell Biol (1982) 1.05

NIH-3T3 cells transformed by the EJ-ras oncogene exhibit reduced platelet-derived growth factor-mediated Ca2+ mobilization. Proc Natl Acad Sci U S A (1988) 1.04

Non-quantal release of acetylcholine at a developing neuromuscular synapse in culture. J Neurosci (1985) 1.03

Changes in the populations of lymphoid cells in human peripheral blood following physical exercise. Clin Exp Immunol (1984) 1.03

Activity-dependent synaptic competition in vitro: heterosynaptic suppression of developing synapses. Science (1991) 1.03

Synaptic reliability correlates with reduced susceptibility to synaptic potentiation by brain-derived neurotrophic factor. Learn Mem (1999) 1.03

A novel membrane sodium current induced by injection of cyclic nucleotides into gastropod neurones. J Physiol (1984) 1.03

Electrical activity in cerebellar cultures determines Purkinje cell dendritic growth patterns. Neuron (1991) 1.02

Spontaneous pyramidal cell death in organotypic slice cultures from rat hippocampus is prevented by glutamate receptor antagonists. Neuroscience (1994) 1.00

Regulation by insulin of a unique neuronal Ca2+ pool and of neuropeptide secretion. Nature (1997) 1.00

Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons. J Neurosci (2001) 1.00

An equivalent circuit for small atrial trabeculae of frog. Biophys J (1975) 0.99

Potentiation of transmitter release by ciliary neurotrophic factor requires somatic signaling. Science (1995) 0.99