Published in Autoimmunity on January 01, 1991
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A (1994) 1.76
Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. J Clin Invest (1994) 1.48
Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells. J Exp Med (1996) 1.39
On the pathogenesis of IDDM. Diabetologia (1994) 1.02
Excessive food intake, obesity and inflammation process in Zucker fa/fa rat pancreatic islets. PLoS One (2011) 0.88
Regulation of electrolyte transport with IL-1beta in rabbit distal colon. Mediators Inflamm (1995) 0.77
Interaction of the islet nitric oxide system with L-arginine-induced secretion of insulin and glucagon in mice. Br J Pharmacol (1996) 0.77
Characterization of mixed syngeneic-allogeneic and syngeneic-xenogeneic islet-graft rejections in mice. Evidence of functional impairment of the remaining syngeneic islets in xenograft rejections. J Clin Invest (1994) 0.75
A protein interaction map of Drosophila melanogaster. Science (2003) 20.06
Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer. Ann Oncol (1997) 4.69
Sexually transmitted infection as a cause of anal cancer. N Engl J Med (1997) 4.05
Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer. Ann Oncol (1996) 4.00
Ventroposterior medial pallidotomy in patients with advanced Parkinson's disease. Neurosurgery (1995) 3.10
Adenovirus 2 early region 1A stimulates expression of both viral and cellular genes. EMBO J (1984) 3.03
Crystal structure of the NG domain from the signal-recognition particle receptor FtsY. Nature (1997) 2.51
The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. Diabetologia (2007) 2.48
Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. Diabetes (2001) 2.20
Adenovirus VA RNAI: a positive regulator of mRNA translation. Mol Cell Biol (1984) 2.09
Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability. J Biol Chem (1985) 2.09
Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA. J Biol Chem (1985) 1.95
Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents. Proc Natl Acad Sci U S A (2006) 1.85
Splicing of adenovirus 2 early region 1A mRNAs is non-sequential. J Mol Biol (1983) 1.82
Adenovirus VA RNAI mediates a translational stimulation which is not restricted to the viral mRNAs. EMBO J (1985) 1.80
Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase. Circulation (2001) 1.79
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A (1994) 1.76
VEGFA and tumour angiogenesis. J Intern Med (2013) 1.74
The advanced health and disaster aid network: a light-weight wireless medical system for triage. IEEE Trans Biomed Circuits Syst (2007) 1.73
Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose. Biochem J (1986) 1.71
An automated flinch detecting system for use in the formalin nociceptive bioassay. J Appl Physiol (1985) (2001) 1.68
Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis. Diabetes (2001) 1.66
Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD. Proc Natl Acad Sci U S A (1998) 1.66
Coronary heart disease mortality and risk among Hispanics and non-Hispanics in Orange County, California. Public Health Rep (1981) 1.65
Prevalence of nasal symptoms and their relation to self-reported asthma and chronic bronchitis/emphysema. Eur Respir J (2001) 1.61
A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells. J Biol Chem (2001) 1.60
The carboxy-terminal region of adenovirus E1A activates transcription through targeting of a C-terminal binding protein-histone deacetylase complex. FEBS Lett (1998) 1.55
Androgen action in the masculinization programming window and development of male reproductive organs. Int J Androl (2009) 1.53
A mechanism by which adenovirus virus-associated RNAI controls translation in a transient expression assay. Mol Cell Biol (1987) 1.53
A genomic-based approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gammaa as a pancreatic beta cell-specific biomarker. Diabetologia (2010) 1.53
Interleukin-1 beta-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase. Endocrinology (1991) 1.52
Plasma exudation as a first line respiratory mucosal defence. Clin Exp Allergy (1991) 1.52
Environmental tobacco smoke and lung cancer in nonsmokers: does time since exposure play a role? Epidemiology (1998) 1.51
Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. J Clin Invest (1994) 1.48
The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells. Diabetologia (1996) 1.48
Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes. Diabetologia (2010) 1.48
Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis. Cell Death Differ (2009) 1.47
Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis. Blood (2000) 1.45
Inhibitory effects of interleukin 1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets. Endocrinology (1987) 1.45
Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays. Diabetes (2001) 1.43
Dose-dependent effects of budesonide aqueous nasal spray on symptoms in a daily nasal allergen challenge model. Ann Allergy Asthma Immunol (2000) 1.42
IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice. Diabetologia (2003) 1.41
The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1. J Neurosci (2001) 1.41
Identification of sequences in Epstein-Barr virus DNA required for the expression of the second Epstein-Barr virus-determined nuclear antigen in COS-1 cells. J Gen Virol (1987) 1.40
Antibiotic Therapy. Can J Comp Med Vet Sci (1949) 1.38
Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells. Diabetologia (2008) 1.34
Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes. Diabetes (1999) 1.34
Final results of a randomised trial comparing 'Tomudex' (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer. "Tomudex" Colorectal Cancer Study Group. Ann Oncol (1996) 1.33
The CtBP binding domain in the adenovirus E1A protein controls CR1-dependent transactivation. Nucleic Acids Res (1996) 1.33
Sodium palmitate induces partial mitochondrial uncoupling and reactive oxygen species in rat pancreatic islets in vitro. Endocrinology (1999) 1.32
Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis. Cell Death Differ (2010) 1.30
Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology (1997) 1.30
Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma. J Biol Chem (1998) 1.30
Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs. Diabetologia (2007) 1.29
Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells. Diabetologia (2001) 1.28
Residential radon exposure and lung cancer in Swedish women. Health Phys (1992) 1.27
Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes. Diabetologia (2012) 1.27
Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-). Diabetes (2000) 1.27
Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells. Diabetologia (1998) 1.25
Abnormalities by pulmonary regions studied with computer tomography following local or local-regional radiotherapy for breast cancer. Int J Radiat Oncol Biol Phys (1999) 1.25
Defective RNA splicing in the absence of adenovirus-associated RNAI. Proc Natl Acad Sci U S A (1986) 1.23
Rapid deposition of amyloid in human islets transplanted into nude mice. Diabetologia (1995) 1.23
The use of the nose to study the inflammatory response of the respiratory tract. Thorax (1992) 1.22
Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis. Diabetes Obes Metab (2013) 1.21
Beta cell proliferation and growth factors. J Mol Med (Berl) (1999) 1.20
Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels. Proc Natl Acad Sci U S A (1989) 1.19
Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis. Diabetologia (2010) 1.16
Background factors in patients with schizoaffective disorder as compared with patients with diabetes and healthy individuals. Eur Arch Psychiatry Clin Neurosci (1996) 1.16
Human pancreatic beta-cell deoxyribonucleic acid-synthesis in islet grafts decreases with increasing organ donor age but increases in response to glucose stimulation in vitro. Endocrinology (1996) 1.16
Volumetric modulated Arc therapy and conventional intensity-modulated radiotherapy for simultaneous maximal intraprostatic boost: a planning comparison study. Clin Oncol (R Coll Radiol) (2009) 1.14
Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets. Diabetologia (2005) 1.13
Crystal structure of phosphoadenylyl sulphate (PAPS) reductase: a new family of adenine nucleotide alpha hydrolases. Structure (1997) 1.13
MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma. Eur J Cancer (2008) 1.12
Generation of CD8(+) T-cell responses to Mycobacterium bovis and mycobacterial antigen in experimental bovine tuberculosis. Infect Immun (1999) 1.12
'Tomudex' (ZD1694): results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia. The 'Tomudex' Colorectal Cancer Study Group. Eur J Cancer (1995) 1.12
Randomized trial of Lichtenstein versus Shouldice hernia repair in general surgical practice. Br J Surg (2002) 1.11
Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas. Cell Death Dis (2013) 1.11
IL-1 receptor antagonist inhibits recurrence of disease after syngeneic pancreatic islet transplantation to spontaneously diabetic non-obese diabetic (NOD) mice. Clin Exp Immunol (1997) 1.10
C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells. Cell Death Differ (2012) 1.10
The social network of patients with schizoaffective disorder as compared to healthy individuals. Soc Sci Med (1995) 1.09
Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis. Diabetologia (2012) 1.09
Cytokines activate the nuclear factor kappa B (NF-kappa B) and induce nitric oxide production in human pancreatic islets. FEBS Lett (1996) 1.09
Mechanisms of coxsackievirus-induced damage to human pancreatic beta-cells. J Clin Endocrinol Metab (2000) 1.09
TNF-alpha and IFN-gamma potentiate the deleterious effects of IL-1 beta on mouse pancreatic islets mainly via generation of nitric oxide. Cytokine (1994) 1.09
Control of adenovirus major late gene expression at multiple levels. J Mol Biol (1992) 1.08
Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice. J Clin Invest (1995) 1.08
Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro. Endocrinology (1990) 1.08
Reversal of beta-cell suppression in vitro in pancreatic islets isolated from nonobese diabetic mice during the phase preceding insulin-dependent diabetes mellitus. J Clin Invest (1990) 1.07
Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis. Biochem Pharmacol (2001) 1.06
Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic beta-cells. Biochem J (1989) 1.06
Enhanced invasive properties of rat embryo fibroblasts transformed by adenovirus E1A mutants with deletions in the carboxy-terminal exon. Oncogene (1992) 1.06
Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms. Diabetologia (2006) 1.06
The future of testis research is turning 6! Six years of international network for young researchers in male fertility. Int J Androl (2012) 1.06
Effect of seasonal allergic rhinitis on airway mucosal absorption of chromium-51 labelled EDTA. Thorax (1993) 1.05