Published in Int J Neuropsychopharmacol on April 01, 2008
Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies. Addict Biol (2011) 1.75
Metabotropic glutamate receptor ligands as potential therapeutics for addiction. Curr Drug Abuse Rev (2009) 1.66
Preclinical studies of alcohol binge drinking. Ann N Y Acad Sci (2011) 1.56
Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism. J Neurosci (2009) 1.47
Neurobiology of alcohol dependence: focus on motivational mechanisms. Alcohol Res Health (2008) 1.29
Differential effects of chronic ethanol consumption and withdrawal on homer/glutamate receptor expression in subregions of the accumbens and amygdala of P rats. Alcohol Clin Exp Res (2009) 1.23
Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intake. Biol Psychiatry (2009) 1.22
Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures. Alcohol Clin Exp Res (2012) 1.19
Pharmacotherapy of alcohol use disorders: seventy-five years of progress. J Stud Alcohol Drugs Suppl (2014) 1.14
Glutamatergic targets for new alcohol medications. Psychopharmacology (Berl) (2013) 1.10
Glutamate transporter 1: target for the treatment of alcohol dependence. Curr Med Chem (2012) 1.09
Accumbens Homer2-mediated signaling: a factor contributing to mouse strain differences in alcohol drinking? Genes Brain Behav (2010) 1.09
Ghrelin receptor antagonism decreases alcohol consumption and activation of perioculomotor urocortin-containing neurons. Alcohol Clin Exp Res (2010) 1.08
Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors. J Pharmacol Exp Ther (2010) 1.07
New insights on neurobiological mechanisms underlying alcohol addiction. Neuropharmacology (2012) 1.07
The central amygdala and alcohol: role of γ-aminobutyric acid, glutamate, and neuropeptides. Cold Spring Harb Perspect Med (2012) 1.04
Neuropeptide modulation of central amygdala neuroplasticity is a key mediator of alcohol dependence. Neurosci Biobehav Rev (2011) 1.04
Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence. BMC Genomics (2013) 1.03
Behavioral actions of alcohol: phenotypic relations from multivariate analysis of mutant mouse data. Genes Brain Behav (2012) 1.00
Brief report: acamprosate in fragile X syndrome. J Autism Dev Disord (2010) 0.99
How adaptation of the brain to alcohol leads to dependence: a pharmacological perspective. Alcohol Res Health (2008) 0.96
Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. Alcohol Clin Exp Res (2014) 0.95
Enhanced sensitivity to attenuation of conditioned reinstatement by the mGluR 2/3 agonist LY379268 and increased functional activity of mGluR 2/3 in rats with a history of ethanol dependence. Neuropsychopharmacology (2011) 0.95
Critical thoughts on current rodent models for evaluating potential treatments of alcohol addiction and withdrawal. Br J Pharmacol (2011) 0.94
The nicotinic acetylcholine receptor partial agonist varenicline increases the ataxic and sedative-hypnotic effects of acute ethanol administration in C57BL/6J mice. Alcohol Clin Exp Res (2010) 0.94
Impact of acamprosate on behavior and brain-derived neurotrophic factor: an open-label study in youth with fragile X syndrome. Psychopharmacology (Berl) (2013) 0.92
Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J mice. Front Neurosci (2014) 0.88
Pharmacological management of binge eating disorder: current and emerging treatment options. Ther Clin Risk Manag (2012) 0.88
The clinical pharmacology of acamprosate. Br J Clin Pharmacol (2014) 0.86
Pharmacological approaches to reducing craving in patients with alcohol use disorders. CNS Drugs (2014) 0.86
Therapeutic potential of metabotropic glutamate receptor modulators. Curr Neuropharmacol (2012) 0.85
Mice lacking Gad2 show altered behavioral effects of ethanol, flurazepam and gabaxadol. Addict Biol (2010) 0.83
An open-label naturalistic pilot study of acamprosate in youth with autistic disorder. J Child Adolesc Psychopharmacol (2011) 0.82
Impact of acamprosate on plasma amyloid-β precursor protein in youth: a pilot analysis in fragile X syndrome-associated and idiopathic autism spectrum disorder suggests a pharmacodynamic protein marker. J Psychiatr Res (2014) 0.82
Molecular Advances Leading to Treatment Implications for Fragile X Premutation Carriers. Brain Disord Ther (2014) 0.81
Effects of alcohol on the membrane excitability and synaptic transmission of medium spiny neurons in the nucleus accumbens. Alcohol (2012) 0.80
Acamprosate-responsive brain sites for suppression of ethanol intake and preference. Am J Physiol Regul Integr Comp Physiol (2011) 0.79
Brief report: Pilot single-blind placebo lead-in study of acamprosate in youth with autistic disorder. J Autism Dev Disord (2014) 0.78
Molecular basis of alcoholism. Handb Clin Neurol (2014) 0.78
Genes and Alcohol Consumption: Studies with Mutant Mice. Int Rev Neurobiol (2016) 0.78
Combined Effects of Acamprosate and Escitalopram on Ethanol Consumption in Mice. Alcohol Clin Exp Res (2016) 0.77
Group 1 mGlu-family proteins promote neuroadaptation to ethanol and withdrawal-associated hippocampal damage. Drug Alcohol Depend (2015) 0.76
The development of acamprosate as a treatment against alcohol relapse. Expert Opin Drug Discov (2014) 0.76
The metabotropic glutamate receptor subtype 5 mediates sensitivity to the sedative properties of ethanol. Pharmacogenet Genomics (2010) 0.76
mGlu receptors and drug addiction. Wiley Interdiscip Rev Membr Transp Signal (2012) 0.76
Frequency of alcohol consumption in humans; the role of metabotropic glutamate receptors and downstream signaling pathways. Transl Psychiatry (2015) 0.76
Pharmacotherapies for Overeating and Obesity. J Genet Syndr Gene Ther (2013) 0.76
Ethanol Consumption in Mice Lacking CD14, TLR2, TLR4, or MyD88. Alcohol Clin Exp Res (2017) 0.76
Alcohol use dependence in fragile X syndrome. Intractable Rare Dis Res (2016) 0.75
Metabotropic and ionotropic glutamate receptors as potential targets for the treatment of alcohol use disorder. Neurosci Biobehav Rev (2017) 0.75
Neurotransmitters in alcoholism: A review of neurobiological and genetic studies. Indian J Hum Genet (2014) 0.75
Glutamate plasticity woven through the progression to alcohol use disorder: a multi-circuit perspective. F1000Res (2017) 0.75
Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice. Physiol Behav (2005) 4.79
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Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice. Nat Neurosci (2001) 3.09
Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J Neurosci (1997) 2.89
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacol Ther (2006) 2.44
Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon. Nat Neurosci (1999) 2.17
Homer2 is necessary for EtOH-induced neuroplasticity. J Neurosci (2005) 2.17
Alcohol-related genes: contributions from studies with genetically engineered mice. Addict Biol (2006) 1.95
Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP. CNS Drug Rev (2006) 1.86
Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking. Neuropsychopharmacology (2006) 1.84
The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice. Psychopharmacology (Berl) (2003) 1.83
mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior. Neuropsychopharmacology (2004) 1.83
Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5. Learn Mem (1999) 1.59
The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice. Psychopharmacology (Berl) (2005) 1.51
The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism. Mol Pharmacol (2004) 1.50
The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats. Psychopharmacology (Berl) (2005) 1.49
Potassium channels as targets for ethanol: studies of G-protein-coupled inwardly rectifying potassium channel 2 (GIRK2) null mutant mice. J Pharmacol Exp Ther (2001) 1.42
A procedure to produce high alcohol intake in mice. Psychopharmacology (Berl) (2004) 1.38
Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors. J Neurosci (2006) 1.35
In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine). Eur J Pharmacol (2003) 1.33
Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties. Drug Alcohol Depend (2006) 1.33
Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J mice. Alcohol Clin Exp Res (2005) 1.27
Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism. Br J Pharmacol (2000) 1.26
The metabotropic glutamate 5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine reduces ethanol self-administration in multiple strains of alcohol-preferring rats and regulates olfactory glutamatergic systems. J Pharmacol Exp Ther (2005) 1.26
Acute dependence on depressant drugs is determined by common genes in mice. J Pharmacol Exp Ther (1991) 1.26
Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice. J Pharmacol Exp Ther (2006) 1.25
Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist. Neuropharmacology (2002) 1.24
Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice. J Neurosci (2005) 1.24
Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol. Neuropsychopharmacology (2005) 1.21
Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes. Mol Pharmacol (1998) 1.19
Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes. Trends Pharmacol Sci (1997) 1.19
Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems. Nat Neurosci (1999) 1.17
Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors. Alcohol Clin Exp Res (2002) 1.11
mGlu5 receptors are involved in the discriminative stimulus effects of self-administered ethanol in rats. Eur J Pharmacol (2006) 1.11
mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors. J Pharmacol Exp Ther (2001) 1.10
Anxiolytic-like activity of the mGluR5 antagonist MPEP: a comparison with diazepam and buspirone. Pharmacol Biochem Behav (2002) 1.08
Alcohol withdrawal reactions and reserpine effects in inbred strains of mice. Life Sci (1974) 0.98
GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilon. Synapse (2006) 0.92
Habituation to test procedure modulates the involvement of dopamine D2- but not D1-receptors in ethanol-induced locomotor stimulation in mice. Psychopharmacology (Berl) (2005) 0.92
The noncompetitive N-methyl-D-aspartate antagonists, MK-801, phencyclidine and ketamine, increase the potency of general anesthetics. Pharmacol Biochem Behav (1990) 0.91
Effects of acamprosate on neuronal receptors and ion channels expressed in Xenopus oocytes. Alcohol Clin Exp Res (2008) 0.89
Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol. Alcohol (2005) 0.89
Effects of 5-HT3, D1 and D2 receptor antagonists on ethanol- and cocaine-induced locomotion. Pharmacol Biochem Behav (1997) 0.88
Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice. Alcohol Clin Exp Res (2007) 0.87
Effects of a metabotropic, mglu5, glutamate receptor antagonist on ethanol consumption by genetic drinking rats. Alcohol Alcohol (2005) 0.86
Loss of flexibility in alcohol-taking rats: promoting factors. Eur Addict Res (2006) 0.85
Ethanol-induced effects on opioid peptides in adult male Wistar rats are dependent on early environmental factors. Neuroscience (2007) 0.84
Effects of D1 dopamine receptor agonists on oral ethanol self-administration in rats: comparison with their efficacy to produce grooming and hyperactivity. Psychopharmacology (Berl) (1999) 0.83
Ethanol dependence and the pituitary-adrenal axis in mice. I. Genotypic differences in hormone levels. Life Sci (1983) 0.79
Biometrical genetic analysis of ethanol's psychomotor stimulant effect. Alcohol Clin Exp Res (1994) 0.78
The anesthetic mechanism of urethane: the effects on neurotransmitter-gated ion channels. Anesth Analg (2002) 3.41
Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proc Natl Acad Sci U S A (2006) 3.04
Nicotine addiction and comorbidity with alcohol abuse and mental illness. Nat Neurosci (2005) 2.59
Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence. J Neurosci (2012) 2.46
Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration. Anesth Analg (2003) 2.41
Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. Neuropsychopharmacology (2005) 2.16
Alcohol-related genes: contributions from studies with genetically engineered mice. Addict Biol (2006) 1.95
Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. J Neurochem (2002) 1.91
The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. J Pharmacol Exp Ther (2005) 1.82
Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies. Addict Biol (2011) 1.75
Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Arch Gen Psychiatry (2006) 1.66
Preclinical studies of alcohol binge drinking. Ann N Y Acad Sci (2011) 1.56
Structural basis for alcohol modulation of a pentameric ligand-gated ion channel. Proc Natl Acad Sci U S A (2011) 1.52
gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions. Biochem Pharmacol (2004) 1.52
Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol. Behav Brain Res (2005) 1.45
Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther (2006) 1.41
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun (2013) 1.35
Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors. J Neurosci (2006) 1.35
Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain. J Neurochem (2004) 1.32
Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J mice. Alcohol Clin Exp Res (2005) 1.27
GABA(A) receptors and alcohol. Pharmacol Biochem Behav (2008) 1.27
Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice. Alcohol Clin Exp Res (2011) 1.27
Up-regulation of microRNAs in brain of human alcoholics. Alcohol Clin Exp Res (2011) 1.26
Studies of ethanol actions on recombinant delta-containing gamma-aminobutyric acid type A receptors yield contradictory results. Alcohol (2007) 1.20
Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. Anesth Analg (2005) 1.19
Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system. PLoS One (2007) 1.19
Effects of alcohols and anesthetics on recombinant voltage-gated Na+ channels. J Pharmacol Exp Ther (2004) 1.18
Sites of excitatory and inhibitory actions of alcohols on neuronal alpha2beta4 nicotinic acetylcholine receptors. J Pharmacol Exp Ther (2003) 1.14
Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. J Pharmacol Exp Ther (2006) 1.14
Role of endocannabinoids in alcohol consumption and intoxication: studies of mice lacking fatty acid amide hydrolase. Neuropsychopharmacology (2006) 1.13
Neuroimmune signaling: a key component of alcohol abuse. Curr Opin Neurobiol (2013) 1.13
Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics. J Biol Chem (2004) 1.10
Amygdala transcriptome and cellular mechanisms underlying stress-enhanced fear learning in a rat model of posttraumatic stress disorder. Neuropsychopharmacology (2010) 1.10
Accessibility to residues in transmembrane segment four of the glycine receptor. Neuropharmacology (2005) 1.08
Cross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activation. J Neurochem (2007) 1.08
Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane. Anesthesiology (2007) 1.07
Sites of alcohol and volatile anesthetic action on glycine receptors. Int Rev Neurobiol (2005) 1.06
The application of proteomics to the human alcoholic brain. Ann N Y Acad Sci (2004) 1.05
Altered gene expression profiles in the frontal cortex of cirrhotic alcoholics. Alcohol Clin Exp Res (2007) 1.05
Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. J Neurosci (2003) 1.04
General anesthetics have additive actions on three ligand gated ion channels. Anesth Analg (2008) 1.03
Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence. BMC Genomics (2013) 1.03
Wheel running, voluntary ethanol consumption, and hedonic substitution. Alcohol (2008) 1.02
delta-Subunit containing GABAA receptor knockout mice are less sensitive to the actions of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol. Eur J Pharmacol (2006) 1.00
Zinc enhances ethanol modulation of the alpha1 glycine receptor. Neuropharmacology (2009) 0.99
Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution. Alcohol Clin Exp Res (2011) 0.99
Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols. J Pharmacol Exp Ther (2011) 0.99
Reduced alcohol consumption in mice lacking preprodynorphin. Alcohol (2006) 0.99
Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs. J Pharmacol Exp Ther (2003) 0.98
Alcohol's effects on brain and behavior. Alcohol Res Health (2010) 0.97
Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit. J Pharmacol Exp Ther (2011) 0.97
Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening. J Neurochem (2004) 0.97
Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation. J Biol Chem (2004) 0.97
n-Alcohols inhibit voltage-gated Na+ channels expressed in Xenopus oocytes. J Pharmacol Exp Ther (2008) 0.97
Gene expression in brain and liver produced by three different regimens of alcohol consumption in mice: comparison with immune activation. PLoS One (2013) 0.96
Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane. Anesth Analg (2004) 0.96
Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. Alcohol Clin Exp Res (2014) 0.95
Molecular mechanism for the dual alcohol modulation of Cys-loop receptors. PLoS Comput Biol (2012) 0.95
Glycine receptors mediate part of the immobility produced by inhaled anesthetics. Anesth Analg (2003) 0.95
Sites in TM2 and 3 are critical for alcohol-induced conformational changes in GABA receptors. J Neurochem (2006) 0.94
A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics. J Pharmacol Exp Ther (2010) 0.94
Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes. FEBS Lett (2010) 0.93
From gene to behavior and back again: new perspectives on GABAA receptor subunit selectivity of alcohol actions. Adv Pharmacol (2006) 0.93
Deletion of the fyn-kinase gene alters sensitivity to GABAergic drugs: dependence on beta2/beta3 GABAA receptor subunits. J Pharmacol Exp Ther (2004) 0.91
Acetylcholine and alcohol sensitivity of neuronal nicotinic acetylcholine receptors: mutations in transmembrane domains. Alcohol Clin Exp Res (2002) 0.91
Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics. Pharmacol Rev (2014) 0.90
Deletion of the fyn-kinase gene alters behavioral sensitivity to ethanol. Alcohol Clin Exp Res (2003) 0.90
Over-expression of the fyn-kinase gene reduces hypnotic sensitivity to ethanol in mice. Neurosci Lett (2004) 0.89
Effects of acamprosate on neuronal receptors and ion channels expressed in Xenopus oocytes. Alcohol Clin Exp Res (2008) 0.89
Are sobriety and consciousness determined by water in protein cavities? Alcohol Clin Exp Res (2004) 0.89
Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol. Alcohol (2005) 0.89
GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites. J Neurochem (2013) 0.88
Synaptic proteome changes in the superior frontal gyrus and occipital cortex of the alcoholic brain. Proteomics Clin Appl (2009) 0.88
Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details. Alcohol Clin Exp Res (2011) 0.88
The effects of volatile aromatic anesthetics on voltage-gated Na+ channels expressed in Xenopus oocytes. Anesth Analg (2008) 0.88
Blockade of the leptin-sensitive pathway markedly reduces alcohol consumption in mice. Alcohol Clin Exp Res (2004) 0.88
Intrathecal veratridine administration increases minimum alveolar concentration in rats. Anesth Analg (2008) 0.87
Nonhalogenated alkanes cyclopropane and butane affect neurotransmitter-gated ion channel and G-protein-coupled receptors: differential actions on GABAA and glycine receptors. Anesthesiology (2002) 0.87
Mutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivo. J Pharmacol Exp Ther (2012) 0.86
Alzheimer's disease and anesthesia: out of body, out of mind...or not? Ann Neurol (2008) 0.86
Proteomic approaches and identification of novel therapeutic targets for alcoholism. Neuropsychopharmacology (2013) 0.85
Inhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sites. Structure (2013) 0.85
Intron 4 containing novel GABAB1 isoforms impair GABAB receptor function. PLoS One (2010) 0.85
Zinc-dependent modulation of α2- and α3-glycine receptor subunits by ethanol. Alcohol Clin Exp Res (2013) 0.85
Ethanol-sensitive sites on the human dopamine transporter. J Biol Chem (2002) 0.84
The TM2 6' position of GABA(A) receptors mediates alcohol inhibition. J Pharmacol Exp Ther (2011) 0.82
Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation. Alcohol (2013) 0.81
Gene expression profiling in blood: new diagnostics in alcoholism and addiction? Neuropsychopharmacology (2009) 0.81
Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels. Mol Pharmacol (2013) 0.81
RNaseIII and T4 polynucleotide Kinase sequence biases and solutions during RNA-seq library construction. Biol Direct (2013) 0.80
Mutation in neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes blocks ethanol action. Addict Biol (2003) 0.79
How Should Addiction-Related Research at the National Institutes of Health be Reorganized? Front Psychiatry (2011) 0.79
Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice. Anesthesiology (2012) 0.78
Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits: Insights from Humans and Mice. Alcohol Res (2012) 0.78
Chronic voluntary alcohol consumption results in tolerance to sedative/hypnotic and hypothermic effects of alcohol in hybrid mice. Pharmacol Biochem Behav (2013) 0.77
Anesthetic-induced immobility: neuronal nicotinic acetylcholine receptors are no longer in the picture. Anesth Analg (2002) 0.76
The minimum alveolar anesthetic concentration of 2-, 3-, and 4-alcohols and ketones in rats: relevance to anesthetic mechanisms. Anesth Analg (2006) 0.76
Using genetically engineered animal models in the postgenomic era to understand gene function in alcoholism. Alcohol Res (2012) 0.76
The effects of anesthetics and ethanol on alpha2 adrenoceptor subtypes expressed with G protein-coupled inwardly rectifying potassium channels in Xenopus oocytes. Anesth Analg (2005) 0.76
Methods for the identification of differentially expressed genes in human post-mortem brain. Methods (2003) 0.76